Title: Santa Fe de Antioquia Holidays 2025 from $571 | Expedia.co.uk [Hotels in Santa Fe de Antioquia](https://expedia.co.uk/Santa-Fe-De-Antioquia-Hotels.d6143343.Travel-Guide-Hotels)[Holiday Rentals in Santa Fe de Antioquia](https://expedia.co.uk/Santa-Fe-De-Antioquia-Holiday-Rentals.d6143343.Travel-Guide-HolidayRentals)[Things to do in Santa Fe de Antioquia](https://expedia.co.uk/Things-To-Do-In-Santa-Fe-De-Antioquia.d6143343.Travel-Guide-Activities)[Santa Fe de Antioquia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Fe-De-Antioquia.d6143343.Car-Hire-Guide) ![](https://images.trvl-media.com/place/6143343/29cd441c-37d2-4bc5-a439-b1f1c5081a7c.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Fe de Antioquia Holidays from £910 ## Book a Hotel + Flight or Car together to unlock savings Photo by Tahino2000 - ## Plan, book, travel with confidence ### Better together Save up to £335 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Packages with flights are ATOL protected #### Your Santa Fe de Antioquia Holiday Lock in a Santa Fe de Antioquia holiday package and get set to experience all this city has to offer. Think about staying in the neighbourhood of Zona Colonial, which is great for shopping, history and bars and pubs. Make your trip to Santa Fe de Antioquia even more fulfilling by including some sightseeing. [Bridge of the West](https://www.expedia.co.uk/Bridge-Of-The-West-Santa-Fe-de-Antioquia.d553248634304588117.Attraction), [Cathedral of Santa Fe de Antioquia](https://www.expedia.co.uk/Cathedral-Of-Santa-Fe-De-Antioquia-Zona-Colonial.d6264612.Attraction) and [Iglesia de Santa Bárbara](https://www.expedia.co.uk/Iglesia-De-Santa-Barbara-Zona-Colonial.d553248621532376358.Attraction) are some of the popular attractions worth exploring. Stop daydreaming and start doing. Browse the many options on Expedia today and put your Santa Fe de Antioquia holiday plans into action! ## Top Santa Fe de Antioquia Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Hotel Park 10](https://images.trvl-media.com/lodging/1000000/30000/28700/28652/20155102_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Park 10 El Poblado £910 per person 30 Oct - 6 Nov found 1 day ago Additional charges may apply Return direct flight included London (LON) to Medellín (MDE) 9.2/10 Wonderful! (1,062 reviews) I like everything about this hotel. The people who work there are so friendly and welcoming. Alejandro is Awesome! Also, I had small concern which I talked to the manager about and she handled it like a boss. Definitely, I will be there when I come back. Thanks Hotel Park 10 Reviewed on 15 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-10-30/2025-11-06/?FromAirport=LON&Destination=MDE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=28652&paandie=true&dealMarker=hY4jPQxZ3_w-N4XsirwCEnFQWzFs-ImvqBsYYwbfe-yNPzgVS6i38az85q5tLTri) ![The Charlee Hotel](https://images.trvl-media.com/lodging/5000000/4130000/4129400/4129341/232f02be_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Charlee Hotel El Poblado £1,099 per person 30 Oct - 6 Nov found 1 day ago Additional charges may apply Return direct flight included London (LON) to Medellín (MDE) 8.8/10 Excellent! (1,004 reviews) First and foremost, every staff member gave such a welcoming vibe. From reception, concierge, garage, and all other staff, they were friendly and their willingness to help really created great impressions throughout the stay. The double room I shared with my cousin was also great to walk into. The two beds (I think queens) were comfortable and felt fresh. There was also the extra lounging space with a panoramic view of the city. The window opens up to let in fresh air if you want some. The area is very close to Lleras so there is noise that goes on throughout the night, but between the bedroom and the extra room there is a sliding door. We never felt that we needed to close it, though and were still able to sleep fine. There is private parking below the hotel. There aren't many spaces for cars, but we only saw one other car a day or two during our stay. The Real restaurant had breakfast included in our rate. The food is delicious! A beef broth soup served daily, and two other dishes that rotate and always include at least one vegetarian option. Fresh fruit that rotates a couple selections daily. Breads, cereals, cheese and meat platter, salad, some pastries, and eggs your way. The omelets... so good. The gym has variety and plenty of equipment. It does get busy in the morning, but we still had no problem working out. And the Envy rooftop area was relaxing and the staff was attentive. Overall, it was a great decision to come here. Reviewed on 13 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-10-30/2025-11-06/?FromAirport=LON&Destination=MDE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=4129341&paandie=true&dealMarker=5NSW5RbLs4apvu7cSDSefF_zgx-22KFRNZgZPo-UC3UABzbjq0ef0f0lId8ULnAM) ![Hotel Du Parc](https://images.trvl-media.com/lodging/7000000/6660000/6658100/6658070/dd698d91_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Du Parc El Poblado £991 per person 30 Oct - 6 Nov found 1 day ago Additional charges may apply Return direct flight included London (LON) to Medellín (MDE) 9.4/10 Exceptional! (1,018 reviews) Such an amazing hotel with so many wonderful staff that go out of their ways to help in any way possible Superb location near pretty much everything in el poblado Reviewed on 14 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-10-30/2025-11-06/?FromAirport=LON&Destination=MDE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=6658070&paandie=true&dealMarker=hY4jPQxZ3_w-N4XsirwCEnFQWzFs-ImvqBsYYwbfe-xRyN1nHNxvUjdhJIOozkNS) ![Hotel El Zarzo](https://images.trvl-media.com/lodging/91000000/90160000/90155600/90155544/f83c1792_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel El Zarzo El Poblado £1,082 per person 30 Oct - 6 Nov found 1 day ago Additional charges may apply Return direct flight included London (LON) to Medellín (MDE) 9.6/10 Exceptional! (218 reviews) El Zarzo staff is the greatest part of the hotel. Extremely attentive, friendly, and informative. Rooftop bar was the highlight for us great drinks and vibes. Down side rooms are smaller then other rooms you can find for this price and the bed was on the firm side. Also while we were there(8/23/25) they are working on expanding so they had construction going on and they like to start at 7am and if your a light sleeper you can hear music/ traffic all night till 3am. Reviewed on 26 Aug 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-10-30/2025-11-06/?FromAirport=LON&Destination=MDE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=90155544&paandie=true&dealMarker=5NSW5RbLs4apvu7cSDSefF_zgx-22KFRNZgZPo-UC3Uyb31DQQOql_XT-7XhK0hg) ![York Luxury Suites Medellín](https://images.trvl-media.com/lodging/50000000/49090000/49084200/49084142/5840e468_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### York Luxury Suites Medellín El Poblado £1,002 per person 30 Oct - 6 Nov found 1 day ago Additional charges may apply Return direct flight included London (LON) to Medellín (MDE) 9.6/10 Exceptional! (1,302 reviews) excelente! la atención súper rápida y buena!! Reviewed on 15 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-10-30/2025-11-06/?FromAirport=LON&Destination=MDE&NumRoom=1&NumAdult=2&NumChild=0&hotelId=49084142&paandie=true&dealMarker=hY4jPQxZ3_w-N4XsirwCEvlDRn7smoSHKQKIYJcYZcMkaGHnahEpwOKWMWS_n2Cz) ## Santa Fe de Antioquia Essential Information | Language | Spanish | | --- | --- | | Currency | Colombian pesos | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Closest Airport | Enrique Olaya Herrera Airport (EOH) | | Population | 11,800 | | Max Temp Winter | 21ºC | | Max Temp Summer | 24ºC | | Top Sights | [Cathedral of Santa Fe de Antioquia](https://www.expedia.co.uk/Cathedral-Of-Santa-Fe-De-Antioquia-Zona-Colonial.d6264612.Attraction), [Museo Juan del Corral](https://www.expedia.co.uk/Museo-Juan-Del-Corral-Zona-Colonial.d553248621532376354.Attraction) and [San Jeronimo Park](https://www.expedia.co.uk/San-Jeronimo-Park-San-Jeronimo.d553248621583444248.Attraction) | ## Top hotels in Santa Fe de Antioquia ![Hotel Boutique Al Alma](https://images.trvl-media.com/lodging/97000000/96670000/96661800/96661794/185fd206_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Boutique Al Alma #9-50 Cra. 8, Santa Fe de Antioquia, Antioquia 9.4/10 Exceptional! (45 reviews) Small and charming hotel "Amazing hotel, we loved every corner. Quiet street and great ambiance." Reviewed on 3 Sept 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=30%2F09%2F2025&endDate=01%2F10%2F2025&selected=96661794&PinnedHotelID=96661794&HadPinnedHotel=true®ionId=6143343) [](https://expedia.co.uk/Hotel-Search?startDate=30%2F09%2F2025&endDate=01%2F10%2F2025&selected=96661794&PinnedHotelID=96661794&HadPinnedHotel=true®ionId=6143343) ![Arde La Selva](https://images.trvl-media.com/lodging/109000000/108290000/108283700/108283692/38d256db_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Arde La Selva km 1 via anza vereda obregon, Santa Fe de Antioquia, Antioquia Fully refundableReserve now, pay when you stay £101 22 Sept - 23 Sept additional charges may apply 9.8/10 Exceptional! (14 reviews) "Everything at Arde la Selva was amazing, the staff is super friendly, food and drinks are great, the premises are really comfortable, pools are great, but ... the music is unnecessarily loud. I understand the afternoons and evenings are more vibrant, but having loud music from 8 am to 12 m prevents ..." Reviewed on 2 Sept 2025 [](https://expedia.co.uk/Hotel-Search?startDate=22%2F09%2F2025&endDate=23%2F09%2F2025&selected=108283692&PinnedHotelID=108283692&HadPinnedHotel=true®ionId=6143343) ![Hotel San Sebastian del Tonusco](https://images.trvl-media.com/lodging/90000000/89940000/89933300/89933227/4fdd9de9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel San Sebastian del Tonusco Carrera 9, Santa Fe de Antioquia Fully refundableReserve now, pay when you stay 8.8/10 Excellent! (38 reviews) A Wonderful and Economical Experience "I was welcomed by three employees of the hotel with such warmth, I immediately felt at home. Laura, in particular, was so attentive to me during my entire stay. I was sad to leave. A wonderful experience. The only caveat is that it's a little far from the main town, but the hotel can arrange for ..." Reviewed on 2 Sept 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=30%2F09%2F2025&endDate=01%2F10%2F2025&selected=89933227&PinnedHotelID=89933227&HadPinnedHotel=true®ionId=6143343) [](https://expedia.co.uk/Hotel-Search?startDate=30%2F09%2F2025&endDate=01%2F10%2F2025&selected=89933227&PinnedHotelID=89933227&HadPinnedHotel=true®ionId=6143343) [See all 490 properties in Santa Fe de Antioquia](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=17%2F09%2F2025&endDate=18%2F09%2F2025®ionId=6143343) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### What to do in Santa Fe de Antioquia ![Live Santa Fe de Antioquia Guided Tour of the Colonial City](https://mediaim.expedia.com/localexpert/49729125/eb29b7e0-a48d-4473-8a7d-2d17a0f7a703.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Meet "The Mother City", Santa Fe de Antioquia £64 per adult [](https://expedia.co.uk/things-to-do/meet-the-mother-city.a49729125.activity-details) ![Tour Santa Fe De Antioquia](https://mediaim.expedia.com/localexpert/2116423/fadf707b-a2b6-410c-ac62-66d234d74874.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Tour Santa Fe De Antioquia £181 per traveller [](https://expedia.co.uk/things-to-do/tour-santa-fe-de-antioquia.a2116423.activity-details) ![Santa Fe de Antioquia Tour with Western Bridge Visit](https://mediaim.expedia.com/localexpert/4228231/74b99ee1-9016-4644-94fe-12a3c57f2d3e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe de Antioquia Tour with Western Bridge Visit £28 per adult [](https://expedia.co.uk/things-to-do/santa-fe-de-antioquia-tour-with-western-bridge-visit.a4228231.activity-details) [See all activities in Santa Fe de Antioquia](https://expedia.co.uk/things-to-do/search?rid=6143343) ## More trip options - 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