Santa Fe de Antioquia Holidays from £188

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Your Santa Fe de Antioquia Holiday

Lock in a Santa Fe de Antioquia holiday package and get set to experience all this city has to offer. Think about staying in the neighbourhood of Zona Colonial, which is great for shopping, history and bars and pubs. Make your trip to Santa Fe de Antioquia even more fulfilling by including some sightseeing. Bridge of the West, Cathedral of Santa Fe de Antioquia and Iglesia de Santa Bárbara are some of the popular attractions worth exploring. Stop daydreaming and start doing. Browse the many options on Expedia today and put your Santa Fe de Antioquia holiday plans into action!

Top Santa Fe de Antioquia Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Golden Valley Hotel

Golden Valley Hotel

3 out of 5
El Poblado
Save 100% on your flight
Price was £316, price is now £188 per person
£188
per person
19 Dec - 22 Dec
found 1 day ago
Additional charges may apply
Return flight included
Cali (CLO) to Medellín (MDE)
9.2/10 Wonderful! (182 reviews)

Aparta Suites Torre Poblado

Aparta Suites Torre Poblado

3 out of 5
El Poblado
Save 100% on your flight
Price was £381, price is now £235 per person
£235
per person
19 Dec - 22 Dec
found 1 day ago
Additional charges may apply
Return flight included
Cali (CLO) to Medellín (MDE)
8.8/10 Excellent! (941 reviews)
Todo excelente y cómodo. Precio muy bueno

Reviewed on 29 Oct 2026

Hotel El Zarzo

Hotel El Zarzo

4 out of 5
El Poblado
Save 100% on your flight
Price was £431, price is now £266 per person
£266
per person
19 Dec - 22 Dec
found 1 day ago
Additional charges may apply
Return flight included
Cali (CLO) to Medellín (MDE)
9.6/10 Exceptional! (321 reviews)
Great clean rooms, attentive staff

Reviewed on 24 Oct 2026

The Charlee Hotel

The Charlee Hotel

5 out of 5
El Poblado
Save 100% on your flight
Price was £451, price is now £281 per person
£281
per person
19 Dec - 22 Dec
found 1 day ago
Additional charges may apply
Return flight included
Cali (CLO) to Medellín (MDE)
8.8/10 Excellent! (1,003 reviews)

Devú

Devú

5 out of 5
El Poblado
Save 100% on your flight
Price was £466, price is now £291 per person
£291
per person
19 Dec - 22 Dec
found 1 day ago
Additional charges may apply
Return flight included
Cali (CLO) to Medellín (MDE)
9.8/10 Exceptional! (43 reviews)

Santa Fe de Antioquia Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Enrique Olaya Herrera Airport (EOH)
Population
11,800
Max Temp Winter
21ºC
Max Temp Summer
24ºC
Top Sights
Cathedral of Santa Fe de Antioquia, Museo Juan del Corral and San Jeronimo Park

Top hotels in Santa Fe de Antioquia

Arde La Selva

Arde La Selva

4 out of 5
km 1 via anza vereda obregon Santa Fe de Antioquia Antioquia
Fully refundableReserve now, pay when you stay
The price is £139 per night from 30 Nov to 1 Dec
£139
30 Nov - 1 Dec
additional charges may apply
9.6/10 Exceptional! (40 reviews)
"Great place, nice environment."

Reviewed on 23 Oct 2026

Arde La Selva
Hotel Mariscal Robledo

Hotel Mariscal Robledo

3 out of 5
Cra 12 No 9 70 Santa Fe de Antioquia Antioquia
The price is £85 per night from 22 Nov to 23 Nov
£85
22 Nov - 23 Nov
additional charges may apply
Hotel Mariscal Robledo
Hotel campestre real

Hotel campestre real

3 out of 5
kilometro 70 via el mar vereda el paso real Santa Fe de Antioquia Antioquia
Fully refundableReserve now, pay when you stay
The price is £49 per night from 2 Nov to 3 Nov
£49
2 Nov - 3 Nov
additional charges may apply
10/10 Exceptional! (1 review)
"Great location near downtown. Quiet area with a nice pool"

Reviewed on 6 May 2026

Hotel campestre real
See all 516 properties in Santa Fe de Antioquia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Stay near popular Santa Fe de Antioquia attractions

Cathedral of Santa Fe de Antioquia

9.0/10 (28 reviews)
You can learn about the history of Santa Fe de Antioquia when you stop by Cathedral of Santa Fe de Antioquia. Make time to visit the monuments and cathedral while you're in the area.
See properties

What to do in Santa Fe de Antioquia

Horseback Riding Tour and Coffee Tour with Lunch and Refreshment

Horseback Riding Tour and Coffee Tour with Lunch and Refreshment

£69
per adult
80% of travellers recommend
Horseback Riding Tour and Coffee Tour with Lunch and Refreshment
Tour Santa Fe de Antioquia

Tour Santa Fe de Antioquia

£116
per adult
Tour Santa Fe de Antioquia
Coffee collection

Coffee tour in Medellín with tastings and transportation

£56
per adult
100% of travellers recommend
Coffee tour in Medellín with tastings and transportation
See all activities in Santa Fe de Antioquia

Frequently asked questions

Why should I book my Santa Fe de Antioquia holiday with Expedia?
Choose Expedia to plan your next escape simply and all in the same place. Our insider tip for getting a great deal on a Santa Fe de Antioquia retreat? Bundle your flights, accommodation and/or hire car into a package holiday. Then add a few awesome tours and activities. Most bookings also include flexible cancellation policies, so there's no need to worry if you have to switch up your travel plans. Round-the-clock assistance with making changes to your trip is on-hand via our Customer Service Portal link.
When is the best time of year to holiday in Santa Fe de Antioquia?
Santa Fe de Antioquia is at its busiest in January, August and November. If you're hoping for a more relaxed getaway, visit in June, July and October. To get an idea of what type of weather you can experience, the average temperature during the day in January, the coolest month in Santa Fe de Antioquia, is 17ºC. The warmest month here is July, when temperatures are around 19ºC.
What are the top hotels for my holiday in Santa Fe de Antioquia?
Many people opt to stay at Pura Vida Eco Hotel in Zona Colonial. If it's your first time in Santa Fe de Antioquia, you're guaranteed a warm welcome here.
How do I get a cheap holiday to Santa Fe de Antioquia?
Combine your hotel and flight bookings, throw in extras such as activities, and save with a Santa Fe de Antioquia holiday. You won't just score awesome discounts on your escape — you'll have a world of choice too. When you book through Expedia, you can select from more than 400 partner airlines and 321,000 hotels around the globe. Your next affordable holiday begins right here, right now! Learn more about how you can save money on your holiday when you combine your hotel and flight bookings with Expedia.
What should I do on my Santa Fe de Antioquia holiday?
Ensure your holiday in Santa Fe de Antioquia is an unforgettable one by taking in its leading attractions. Bridge of the West, Cathedral of Santa Fe de Antioquia, Iglesia de Santa Bárbara and Church of Our Lady of Chinquinquira are a few of the things you should see while you're in this city.
What is the best area to stay in when on holiday in Santa Fe de Antioquia?
There's loads to do in Santa Fe de Antioquia, so stay near its best attractions and maximise your time sightseeing. Bridge of the West is one place to put on your itinerary.
Do I need a visa for my Santa Fe de Antioquia holiday?
Visa requirements for Santa Fe de Antioquia vary depending on your nationality and reason for your visit. Make sure you check official government websites to determine if you need a visa for your trip. They'll give you the most up-to-date information, including details about application procedures or supporting documentation you might need. Research your visa requirements well ahead of time to ensure a smooth travel experience. Finally, check to see that your passport has at least six months validity from your planned date of return.
What should I wear on my Santa Fe de Antioquia holiday?
Although everyone's fashion style differs, it can be helpful to have some guidelines for what to bring during your holiday in Santa Fe de Antioquia. Think about looking up style blogs before leaving for inspiration on local dress codes or fashion trends. Pack your bags with confidence by checking the weather forecast in Santa Fe de Antioquia. July brings the warmest temperatures, with daytime averages of 19ºC, while January days average 17ºC, making it the coolest month.
What does an Expedia Santa Fe de Antioquia holiday include?
Flights, hotels and a reliable car for all your road trip adventures. Simply choose your preferred bundle and gain access to great discounts. Once you've made your booking, add on some sightseeing tours and watch your savings stack up. When it comes to planning your Santa Fe de Antioquia holiday, you're in charge! Discover an excellent range of property types and pick one that matches your group size. The most in-demand rentals here are hotels and villas. With Expedia, you can easily tailor your Santa Fe de Antioquia escape just the way you like.
Does Expedia offer Book Now, Pay Later Santa Fe de Antioquia holidays?
We do. Expedia has teamed up with online lender Klarna to help you easily pay for your holiday in manageable instalments. Simply click on the payment plan best suited to your needs during checkout and take the stress out of budgeting for your next trip. Remember to bundle your flights, car hire and hotel with Expedia to get the biggest bang for your travel buck. Take a look at our flexible payment options below:

  • Pay monthly holidays: Realise your holiday dreams sooner with Klarna's easy monthly instalment plans. If paying in multiple instalments sounds right for you, choose this option at checkout.
  • No-deposit holidays: When you want to grab an unbeatable deal but your budget doesn't quite cover it yet, Klarna's no-deposit holiday plan will allow you to Book Now, Pay Later to get what you want.

Can I choose my airline with a Santa Fe de Antioquia Expedia holiday?
Yes — and it's easy too. Expedia has access to more than 400 partner airlines all over the world. Our packages give you the freedom to take your pick of available flights, hotels and activities that fit your needs.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.