Title: Santa Fe de Antioquia Holidays 2026 from £363 | Expedia.co.uk [Hotels in Santa Fe de Antioquia](https://expedia.co.uk/Santa-Fe-De-Antioquia-Hotels.d6143343.Travel-Guide-Hotels)[Holiday Rentals in Santa Fe de Antioquia](https://expedia.co.uk/Santa-Fe-De-Antioquia-Holiday-Rentals.d6143343.Travel-Guide-HolidayRentals)[Things to do in Santa Fe de Antioquia](https://expedia.co.uk/Things-To-Do-In-Santa-Fe-De-Antioquia.d6143343.Travel-Guide-Activities)[Santa Fe de Antioquia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Fe-De-Antioquia.d6143343.Car-Hire-Guide) ![](https://images.trvl-media.com/place/6143343/29cd441c-37d2-4bc5-a439-b1f1c5081a7c.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Fe de Antioquia Holidays from £363 ## Book a Hotel + Flight or Car together to unlock savings Photo by Tahino2000 - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected #### Your Santa Fe de Antioquia Holiday Lock in a Santa Fe de Antioquia holiday package and get set to experience all this city has to offer. Think about staying in the neighbourhood of Zona Colonial, which is great for shopping, history and bars and pubs. Make your trip to Santa Fe de Antioquia even more fulfilling by including some sightseeing. [Bridge of the West](https://www.expedia.co.uk/Bridge-Of-The-West-Santa-Fe-de-Antioquia.d553248634304588117.Attraction), [Cathedral of Santa Fe de Antioquia](https://www.expedia.co.uk/Cathedral-Of-Santa-Fe-De-Antioquia-Zona-Colonial.d6264612.Attraction) and [Iglesia de Santa Bárbara](https://www.expedia.co.uk/Iglesia-De-Santa-Barbara-Zona-Colonial.d553248621532376358.Attraction) are some of the popular attractions worth exploring. Stop daydreaming and start doing. Browse the many options on Expedia today and put your Santa Fe de Antioquia holiday plans into action! ## Top Santa Fe de Antioquia Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Hotel Casa 73 Deluxe](https://images.trvl-media.com/lodging/112000000/111550000/111544100/111544099/8ba8cc66_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Casa 73 Deluxe Laureles - Estadio £363 per person 16 Mar - 21 Mar found 12 hours ago Additional charges may apply Return direct flight included New York (NYC) to Medellín (MDE) 9.2/10 Wonderful! (9 reviews) Same breakfast every day Reviewed on 15 Nov 2025 ![Cannúa Lodge](https://images.trvl-media.com/lodging/33000000/32520000/32518200/32518199/710d3edc_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Cannúa Lodge £551 per person 16 Mar - 21 Mar found 12 hours ago Additional charges may apply Return direct flight included New York (NYC) to Medellín (MDE) 9/10 Wonderful! (32 reviews) Amazing nature reserve. Five star food quality! Responsive staff. Reviewed on 17 Sept 2025 ![Movich Hotel Las Lomas](https://images.trvl-media.com/lodging/1000000/520000/519900/519824/4d45af49_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Movich Hotel Las Lomas £619 per person 16 Mar - 21 Mar found 12 hours ago Additional charges may apply Return direct flight included New York (NYC) to Medellín (MDE) 9/10 Wonderful! (1,005 reviews) Room needs some refreshing Staff ok Bell man was good Bar was supposed to be open but they closed it begore Reviewed on 15 Jan 2026 ![Autenthico Sajonia Hotel Aeropuerto](https://images.trvl-media.com/lodging/108000000/107130000/107126600/107126596/14bc5c70_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Autenthico Sajonia Hotel Aeropuerto £434 per person 16 Mar - 21 Mar found 12 hours ago Additional charges may apply Return direct flight included New York (NYC) to Medellín (MDE) 9.2/10 Wonderful! (68 reviews) el lugar es perfecto, todo es hermoso y tranquilo Reviewed on 14 Jan 2026 ![finca hotel zona franca](https://images.trvl-media.com/lodging/91000000/90830000/90820100/90820058/w3280h1668x0y0-bf1554ab_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### finca hotel zona franca £401 per person 16 Mar - 21 Mar found 12 hours ago Additional charges may apply Return direct flight included New York (NYC) to Medellín (MDE) 7/10 Good! (4 reviews) There's a bitter guy at Reception. It should b good 2 find someone who can enjoy life just 4 been alive. If you are leaving before 6am, you won't have shuttle to airport neither breakfast. Reviewed on 18 Jan 2026 ## Santa Fe de Antioquia Essential Information | Language | Spanish | | --------------- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Colombian pesos | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Closest Airport | Enrique Olaya Herrera Airport (EOH) | | Population | 11,800 | | Max Temp Winter | 21ºC | | Max Temp Summer | 24ºC | | Top Sights | [Cathedral of Santa Fe de Antioquia](https://www.expedia.co.uk/Cathedral-Of-Santa-Fe-De-Antioquia-Zona-Colonial.d6264612.Attraction), [Museo Juan del Corral](https://www.expedia.co.uk/Museo-Juan-Del-Corral-Zona-Colonial.d553248621532376354.Attraction) and [San Jeronimo Park](https://www.expedia.co.uk/San-Jeronimo-Park-San-Jeronimo.d553248621583444248.Attraction) | ## Top hotels in Santa Fe de Antioquia ![Arde La Selva](https://images.trvl-media.com/lodging/109000000/108290000/108283700/108283692/38d256db_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Arde La Selva km 1 via anza vereda obregon Santa Fe de Antioquia Antioquia Fully refundableReserve now, pay when you stay £104 9 Feb - 10 Feb additional charges may apply 9.8/10 Exceptional! (24 reviews) The room was clean, the property was absolutely gorgeous, the staff excells in customer service Reviewed on 16 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=09%2F02%2F2026&endDate=10%2F02%2F2026&selected=108283692&PinnedHotelID=108283692&HadPinnedHotel=true®ionId=6143343) ![Hotel San Sebastian del Tonusco](https://images.trvl-media.com/lodging/90000000/89940000/89933300/89933227/4fdd9de9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel San Sebastian del Tonusco Carrera 9 Santa Fe de Antioquia Fully refundableReserve now, pay when you stay 8.8/10 Excellent! (43 reviews) Two nice swimming calls, very friendly staff, safe, walk to town Reviewed on 20 Nov 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=89933227&PinnedHotelID=89933227&HadPinnedHotel=true®ionId=6143343) [](https://expedia.co.uk/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=89933227&PinnedHotelID=89933227&HadPinnedHotel=true®ionId=6143343) ![Hotel Boutique Al Alma](https://images.trvl-media.com/lodging/97000000/96670000/96661800/96661794/185fd206_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Boutique Al Alma #9-50 Cra. 8 Santa Fe de Antioquia Antioquia 9.4/10 Exceptional! (53 reviews) Wonderful place,very confortable,clean and pretty . Very nice,friendly,warm and helpful staff. The included breakfast is a la cart,including eggs Benedict with no time limit. The girl at the front desk,very sweet,explained graciously and in detail all places worth visiting. We were very satisfied ... Reviewed on 28 Jan 2026 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=96661794&PinnedHotelID=96661794&HadPinnedHotel=true®ionId=6143343) [](https://expedia.co.uk/Hotel-Search?startDate=13%2F02%2F2026&endDate=14%2F02%2F2026&selected=96661794&PinnedHotelID=96661794&HadPinnedHotel=true®ionId=6143343) [See all 455 properties in Santa Fe de Antioquia](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=31%2F01%2F2026&endDate=01%2F02%2F2026®ionId=6143343) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### What to do in Santa Fe de Antioquia ![Santa Fe de Antioquia Tour with Western Bridge Visit](https://mediaim.expedia.com/localexpert/4228231/74b99ee1-9016-4644-94fe-12a3c57f2d3e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Santa Fe de Antioquia Tour with Western Bridge Visit £28 per adult [](https://expedia.co.uk/things-to-do/santa-fe-de-antioquia-tour-with-western-bridge-visit.a4228231.activity-details) ![Horseback Riding Tour and Coffee Tour with Lunch and Refreshment](https://mediaim.expedia.com/localexpert/50756334/1f9f6580-6b1d-4aa0-be66-471f1a3eed66.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Horseback Riding Tour and Coffee Tour with Lunch and Refreshment £51 per adult [](https://expedia.co.uk/things-to-do/horseback-riding-tour-and-coffee-tour-with-lunch-and-refreshment.a50756334.activity-details) ![Live Santa Fe de Antioquia Guided Tour of the Colonial City](https://mediaim.expedia.com/localexpert/49729125/eb29b7e0-a48d-4473-8a7d-2d17a0f7a703.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Meet "The Mother City", Santa Fe de Antioquia £65 per adult [](https://expedia.co.uk/things-to-do/meet-the-mother-city.a49729125.activity-details) [See all activities in Santa Fe de Antioquia](https://expedia.co.uk/things-to-do/search?rid=6143343) ## Explore a world of travel with Expedia - 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[Lleras Park ](https://www.expedia.co.uk/Lleras-Park-El-Poblado.d6166214.Attraction) - [Medellin Botanical Garden ](https://www.expedia.co.uk/Medellin-Botanical-Garden-Aranjuez.d6272363.Attraction) - [Visit Castilla ](https://www.expedia.co.uk/Medellin-Castilla.dx553248635976386911) - [Visit Corazon de Jesus ](https://www.expedia.co.uk/Medellin-Corazon-De-Jesus.dx553248635976396980) - [Visit La América ](https://www.expedia.co.uk/Medellin-La-America.dx553248635976387558) - [Visit La Candelaria ](https://www.expedia.co.uk/Medellin-La-Candelaria.dx6270633) - [Visit Laureles - Estadio ](https://www.expedia.co.uk/Medellin-Laureles-Estadio.dx553248635976384376) - [Visit Laureles ](https://www.expedia.co.uk/Medellin-Laureles.dx6270645) - [Visit Robledo ](https://www.expedia.co.uk/Medellin-Robledo.dx553248635976386879) - [Medellin Holidays ](https://www.expedia.co.uk/Medellin.d2246.Holidays-City-Breaks) - [Medellín Holidays ](https://www.expedia.co.uk/Medellin.d6140804.Holidays-City-Breaks) - [Visit Medellin ](https://www.expedia.co.uk/Medellin.dx2246) - [Peñol-Guatapé Reservoir ](https://www.expedia.co.uk/Penol-Guatape-Reservoir-Antioquia.d670728107560771584.Attraction) - [Pueblito Paisa ](https://www.expedia.co.uk/Pueblito-Paisa-Medellin.d6272340.Attraction) - [Rionegro Holidays ](https://www.expedia.co.uk/Rionegro.d181446.Holidays-City-Breaks) - [Rock of Guatapé ](https://www.expedia.co.uk/Rock-Of-Guatape-Guatape.d6292538.Attraction) - [San Diego Holidays ](https://www.expedia.co.uk/San-Diego.d6323725.Holidays-City-Breaks) - [Visit San Jerónimo ](https://www.expedia.co.uk/San-Jeronimo.dx6270869) - [San Nicolás Mall ](https://www.expedia.co.uk/San-Nicolas-Mall-Rionegro.d553248635188837460.Attraction) - [Santa Elena Holidays ](https://www.expedia.co.uk/Santa-Elena.d3000006100.Holidays-City-Breaks) - [Santafé Mall ](https://www.expedia.co.uk/Santafe-Mall-El-Poblado.d6160635.Attraction) - [Sede Atletico Nacional ](https://www.expedia.co.uk/Sede-Atletico-Nacional-Guarne.d644120646892929024.Attraction) - [Somer Clinic ](https://www.expedia.co.uk/Somer-Clinic-Rionegro.d553248635976333500.Attraction) - [Visit Sopetrán ](https://www.expedia.co.uk/Sopetran.dx3000006094) - [Car hire Bello ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Bello.d6245393.Car-Hire-Guide) - [Car hire near Centro Comercial Los Molinos ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Centro-Comercial-Los-Molinos.d688666727383367680.Car-Hire-Guide) - [Car hire near Medellin ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Medellin.d2246.Car-Hire-Guide) - [Things to do in Medellin ](https://www.expedia.co.uk/Things-To-Do-In-Medellin.d2246.Travel-Guide-Activities) - [Things to do in Medellín ](https://www.expedia.co.uk/Things-To-Do-In-Medellin.d6140804.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. 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