Santa Fe de Antioquia Holidays from £929
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Santa Fe de Antioquia Holiday
Lock in a Santa Fe de Antioquia holiday package and get set to experience all this city has to offer. Think about staying in the neighbourhood of Zona Colonial, which is great for shopping, history and bars and pubs. Make your trip to Santa Fe de Antioquia even more fulfilling by including some sightseeing. Bridge of the West, Cathedral of Santa Fe de Antioquia and Iglesia de Santa Bárbara are some of the popular attractions worth exploring. Stop daydreaming and start doing. Browse the many options on Expedia today and put your Santa Fe de Antioquia holiday plans into action!
Top Santa Fe de Antioquia Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
Hotel Casa 10 Medellin
El Poblado
£947
per person
3 Nov - 8 Nov
found 1 day ago
Additional charges may apply
Return direct flight included
London (LHR) to Medellín (MDE)
8/10 Very good! (34 reviews)
Buenas tardes los cuartos son incomodos(chiquitos), los matres duros y las fotos que están para uno escogerlo no son iguales a cuando uno llega
Reviewed on 9 Aug 2026
Santa Fe de Antioquia Essential Information
Language | Spanish |
|---|---|
Currency | Colombian pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Enrique Olaya Herrera Airport (EOH) |
Population | 11,800 |
Max Temp Winter | 21ºC |
Max Temp Summer | 24ºC |
Top Sights | Cathedral of Santa Fe de Antioquia, Museo Juan del Corral and San Jeronimo Park |
Top hotels in Santa Fe de Antioquia
Arde La Selva
km 1 via anza vereda obregon Santa Fe de Antioquia Antioquia
Fully refundableReserve now, pay when you stay
£122
15 Oct - 16 Oct
additional charges may apply
Ivanna Hotel Campestre - Santa Fe de Antioquia
Via Anza Vereda, KM 1, Obregon Santa Fe de Antioquia Antioquia
Fully refundable
£52
21 Sept - 22 Sept
additional charges may apply
7.6/10 Good! (9 reviews)
"Amazing staff, Swimming pool and spa Hot tub Wonderful area secluded Relaxing atmosphere with all the amenities"
Reviewed on 30 Aug 2026
Entrecielos
Carrera 9 Santa Fe de Antioquia
Fully refundableReserve now, pay when you stay
£54
16 Sept - 17 Sept
additional charges may apply
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Fe de Antioquia attractions
Cathedral of Santa Fe de Antioquia
9.0/10 (28 reviews)
You can learn about the history of Santa Fe de Antioquia when you stop by Cathedral of Santa Fe de Antioquia. Make time to visit the monuments and cathedral while you're in the area.
Bridge of the West
9.0/10 (19 reviews)
After visiting Bridge of the West, make a plan to see the other sights and activities in Santa Fe de Antioquia. Make time to visit the cathedral and monuments while you're in the area.
Iglesia de Santa Bárbara
9.4/10 (17 reviews)
After visiting Iglesia de Santa Bárbara, make a plan to see the other sights and activities in Santa Fe de Antioquia. Wander the riverfront and parks while you're in the area.
Bolivar Square
9.2/10 (30 reviews)
Learn about the local history of Santa Fe de Antioquia when you spend time at Bolivar Square. Stroll along the riverfront or experience the area's festivals.
Church of Our Lady of Chinquinquira
9.2/10 (19 reviews)
Church of Our Lady of Chinquinquira is just one of the places to see in Santa Fe de Antioquia, so why not enjoy the other things to explore during your travels? Amble around the area's riverfront or visit its monuments.
Casa Atanasio Girardot
8.6/10 (9 reviews)
You can spend an afternoon studying the exhibits at Casa Atanasio Girardot in Santa Fe de Antioquia.
Museo Juan del Corral
9.4/10 (10 reviews)
You can browse the exhibits at Museo Juan del Corral, a museum with a story of its own, during your travels to Santa Fe de Antioquia. Stroll along the riverfront or experience the area's festivals.
Catedral Basílica Metropolitana de la Inmaculada Concepción
9.2/10 (19 reviews)
Catedral Basílica Metropolitana de la Inmaculada Concepción is just one of the places to see in Santa Fe de Antioquia, so why not enjoy the other things to explore during your travels?
What to do in Santa Fe de Antioquia
Horseback Riding Tour and Coffee Tour with Lunch and Refreshment
£67
per adult
Coffee tour in Medellín with tastings and transportation
£55
per adult
100% of travellers recommend
Frequently asked questions
Why should I book my Santa Fe de Antioquia holiday with Expedia?
Choose Expedia to plan your next escape simply and all in the same place. Our insider tip for getting a great deal on a Santa Fe de Antioquia retreat? Bundle your flights, accommodation and/or hire car into a package holiday. Then add a few awesome tours and activities. Most bookings also include flexible cancellation policies, so there's no need to worry if you have to switch up your travel plans. Round-the-clock assistance with making changes to your trip is on-hand via our Customer Service Portal link.
When is the best time of year to holiday in Santa Fe de Antioquia?
Santa Fe de Antioquia is at its busiest in January, August and November. If you're hoping for a more relaxed getaway, visit in June, July and October. To get an idea of what type of weather you can experience, the average temperature during the day in January, the coolest month in Santa Fe de Antioquia, is 17ºC. The warmest month here is July, when temperatures are around 19ºC.
What are the top hotels for my holiday in Santa Fe de Antioquia?
Many people opt to stay at Pura Vida Eco Hotel in Zona Colonial. If it's your first time in Santa Fe de Antioquia, you're guaranteed a warm welcome here.
How do I get a cheap holiday to Santa Fe de Antioquia?
Combine your hotel and flight bookings, throw in extras such as activities, and save with a Santa Fe de Antioquia holiday. You won't just score awesome discounts on your escape — you'll have a world of choice too. When you book through Expedia, you can select from more than 400 partner airlines and 321,000 hotels around the globe. Your next affordable holiday begins right here, right now! Learn more about how you can save money on your holiday when you combine your hotel and flight bookings with Expedia.
What should I do on my Santa Fe de Antioquia holiday?
Ensure your holiday in Santa Fe de Antioquia is an unforgettable one by taking in its leading attractions. Bridge of the West, Cathedral of Santa Fe de Antioquia, Iglesia de Santa Bárbara and Church of Our Lady of Chinquinquira are a few of the things you should see while you're in this city.
What is the best area to stay in when on holiday in Santa Fe de Antioquia?
There's loads to do in Santa Fe de Antioquia, so stay near its best attractions and maximise your time sightseeing. Bridge of the West is one place to put on your itinerary.
Do I need a visa for my Santa Fe de Antioquia holiday?
Visa requirements for Santa Fe de Antioquia vary depending on your nationality and reason for your visit. Make sure you check official government websites to determine if you need a visa for your trip. They'll give you the most up-to-date information, including details about application procedures or supporting documentation you might need. Research your visa requirements well ahead of time to ensure a smooth travel experience. Finally, check to see that your passport has at least six months validity from your planned date of return.
What should I wear on my Santa Fe de Antioquia holiday?
Although everyone's fashion style differs, it can be helpful to have some guidelines for what to bring during your holiday in Santa Fe de Antioquia. Think about looking up style blogs before leaving for inspiration on local dress codes or fashion trends. Pack your bags with confidence by checking the weather forecast in Santa Fe de Antioquia. July brings the warmest temperatures, with daytime averages of 19ºC, while January days average 17ºC, making it the coolest month.
What does an Expedia Santa Fe de Antioquia holiday include?
Flights, hotels and a reliable car for all your road trip adventures. Simply choose your preferred bundle and gain access to great discounts. Once you've made your booking, add on some sightseeing tours and watch your savings stack up. When it comes to planning your Santa Fe de Antioquia holiday, you're in charge! Discover an excellent range of property types and pick one that matches your group size. The most in-demand rentals here are hotels and villas. With Expedia, you can easily tailor your Santa Fe de Antioquia escape just the way you like.
Does Expedia offer Book Now, Pay Later Santa Fe de Antioquia holidays?
We do. Expedia has teamed up with online lender Klarna to help you easily pay for your holiday in manageable instalments. Simply click on the payment plan best suited to your needs during checkout and take the stress out of budgeting for your next trip. Remember to bundle your flights, car hire and hotel with Expedia to get the biggest bang for your travel buck. Take a look at our flexible payment options below:
- Pay monthly holidays: Realise your holiday dreams sooner with Klarna's easy monthly instalment plans. If paying in multiple instalments sounds right for you, choose this option at checkout.
- No-deposit holidays: When you want to grab an unbeatable deal but your budget doesn't quite cover it yet, Klarna's no-deposit holiday plan will allow you to Book Now, Pay Later to get what you want.
Can I choose my airline with a Santa Fe de Antioquia Expedia holiday?
Yes — and it's easy too. Expedia has access to more than 400 partner airlines all over the world. Our packages give you the freedom to take your pick of available flights, hotels and activities that fit your needs.
Explore a world of travel with Expedia
- 5 Star Hotels in Laureles
- 5 Star Hotels in Medellín
- Bella Luz Hotels
- Castilla Hotels
- Libertg Hotels Spa Medellin
- Spacious 8
- El Poblado Hotels
- La Candelaria Hotels
- Laureles - Estadio Hotels
- Laureles Hotels
- Apartments in Medellín
- Hostels in Medellín
- Ac
- Adults Only Resorts & in Medellín
- The Art Hotel Medellin
- Hotel Midas
- Beach Resorts & in Medellín
- Beautiful house in one of the most beauty places in Jerico
- City Express Plus by Marriott Medellin Colombia
- El Poblado 3 Bedroom Luxury Apartment with Breathtaking Views
- Elemont Hotel
- Espectacular Finca en Tierra Caliente cerca a Medellin
- Luxury Apartment with A/C at Energy Living
- Gay-Friendly Hotels in Medellín
- Historic Hotels in Medellín
- Hostal Experience B&B Estadio
- Heiss Hotel By Jalo
- Hotel Greenview Medellin
- Hotel Verony San Joaquín
- Hotels with Babysitting Services in Medellín
- Hotels with Gym in Medellín
- Hotels with Hot Tubs in Medellín
- Tribe Medellín
- La Mansion Lleras
- Loslan Real Estate
- Luxury Hotels in Medellín
- Luxury Penthouse with awesome view and jacuzzi
- Luxury Room with Jacuzzi
- Manila House
- Masaya Medellin
- Mountain Hotels in Medellín
- Parque Lleras Luxury 4br apartment
- Royal Living Poblado
- Socialtel Provenza Medellin
- Sites Hotel
- Spa Hotels in Medellín
- The Cut Hotel
- The Fortress @ LLeras Park (5 Bedrooms)
- The Icon Resort
- The MYNT @ Lleras Park [10 Master Bedrooms]
- The Somos Loho Hotel
- The Somos Beats Hotel & Rooftop
- Unique Duplex penthouse w / Jacuzzi & Large Terrace. Great Location
- Loma
- Wedding Hotels in Medellín
- Medellín Hotels
- Villas in Medellín
- Morro de Moravia Hotels
- Robledo Hotels
- Escápate a una Finca acogedora en San Jerónimo con piscina
- Paradise in San Jeronimo With Air Conditioning and Pool
- Ab del Sol Campestre
- Gay-Friendly Hotels in Santa Fe de Antioquia
- Hotel y Spa Santa Fe Colonial
- Casa Candela
- Kairos Finca de lujo en Sopetrán con piscina
- Antioquia Holidays
- Visit Bello
- Botero Plaza
- Carlos Vieco Theatre
- El Poblado Holidays
- Girardota Holidays
- Itagüí Holidays
- Visit Castilla
- Visit Corazon de Jesus
- Visit La Candelaria
- Visit Laureles - Estadio
- Visit Laureles
- Visit Manrique
- Visit Robledo
- Medellín Holidays
- Visit Medellín
- Pueblito Paisa
- Visit San Jerónimo
- Santa Elena Holidays
- Santafé Mall
- Visit Sopetrán
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
