Title: TOP Business Hotels in Santa Cruz for 2026 |  Expedia.co.uk

[Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d6047957.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6047957.Travel-Guide-HolidayRentals)[Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6047957.Travel-Guide-Flights)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d6047957.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6047957.Holidays-City-Breaks)

![Rows of vineyards, Santa Cruz, Chile](https://images.trvl-media.com/place/6047957/e58d3014-ef10-4c60-9e03-08890e2f5494.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Search Business Hotels in Santa Cruz

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## Check availability on Santa Cruz Business Hotels

Tonight

[29 Dec - 30 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6047957&startDate=2025-12-29&endDate=2025-12-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Tomorrow

[30 Dec - 31 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6047957&startDate=2025-12-30&endDate=2025-12-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

This weekend

[2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6047957&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

Next weekend

[9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6047957&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly)

## Our top choices for Santa Cruz business-friendly hotels

![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/3fe1c8d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/b6c7442f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Twin Room | Minibar, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/4b01e3a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property – evening/night](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/75df94bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Santa Cruz Plaza

[](https://www.expedia.co.uk/San-Fernando-Hotels-Santa-Cruz-Plaza.h1406642.Hotel-Information)

Santa Cruz

8.6/10

Excellent

(335)

"Yes all great."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barrett

£96

13 Jan - 14 Jan 2026

[](https://www.expedia.co.uk/San-Fernando-Hotels-Santa-Cruz-Plaza.h1406642.Hotel-Information)

![Seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/afe65d1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/3c454a0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free self-parking](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/e7b99456.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/d646bdcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Perla Hotel

[](https://www.expedia.co.uk/San-Fernando-Hotels-La-Perla-Hotel.h18057456.Hotel-Information)

Santa Cruz

9.2/10

Wonderful

(102)

"Nice stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

George

[](https://www.expedia.co.uk/San-Fernando-Hotels-La-Perla-Hotel.h18057456.Hotel-Information)

![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/08e2ca8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite | Living room | TV](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/f87c655e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/7a4b1beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/c669d7a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TerraViña

[](https://www.expedia.co.uk/San-Fernando-Hotels-TerraVina.h3775207.Hotel-Information)

Santa Cruz

9.2/10

Wonderful

(204)

"It is situated in the midfle of a vineyard - so it is certainly quiet. Great base for exploring (by own car or taxi) the Uco Valley. It is a 20 minute walk to the road! Simple but stylish place. Gym is just for show… $300 dollars would sort it out! Staff were very helpful. This is a unique place for a wine aficionado! "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Paul

£120

30 Dec - 31 Dec

[](https://www.expedia.co.uk/San-Fernando-Hotels-TerraVina.h3775207.Hotel-Information)

![Front of property – evening/night](https://images.trvl-media.com/lodging/3000000/2960000/2959500/2959484/e99bf923.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/3000000/2960000/2959500/2959484/e7b15bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Library](https://images.trvl-media.com/lodging/3000000/2960000/2959500/2959484/ea8292f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2960000/2959500/2959484/b2873520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Boutique Vendimia Premium

[](https://www.expedia.co.uk/San-Fernando-Hotels-Hotel-Boutique-Vendimia-Premium.h2959484.Hotel-Information)

Santa Cruz

9.2/10

Wonderful

(136)

"Loved the rustic hotel and Mauricio and Carla are awesome hosts! Great location and an amazing place to stay. Highly recommended. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Orlando

£90

30 Dec - 31 Dec

[](https://www.expedia.co.uk/San-Fernando-Hotels-Hotel-Boutique-Vendimia-Premium.h2959484.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/30000000/29060000/29053800/29053727/10d3ee66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/30000000/29060000/29053800/29053727/d7a30fa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/30000000/29060000/29053800/29053727/9d478df1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/30000000/29060000/29053800/29053727/2f8bdbfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Ontiveros

[](https://www.expedia.co.uk/San-Fernando-Hotels-Hotel-Ontiveros.h29053727.Hotel-Information)

San Fernando

9.6/10

Exceptional

(21)

"Amplia y comoda habitacion. Personal de recepcion muy amable y colaborador "

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

Eileen

[](https://www.expedia.co.uk/San-Fernando-Hotels-Hotel-Ontiveros.h29053727.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/88000000/87720000/87715000/87714974/8ef18f8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/88000000/87720000/87715000/87714974/743ff8ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/88000000/87720000/87715000/87714974/af54bde9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/88000000/87720000/87715000/87714974/3c752c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Boutique Raices

[](https://www.expedia.co.uk/Curico-Hotels-Hotel-Boutique-Raices.h87714974.Hotel-Information)

Curicó

9.4/10

Exceptional

(40)

"I enjoyed my stay here. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Nick

[](https://www.expedia.co.uk/Curico-Hotels-Hotel-Boutique-Raices.h87714974.Hotel-Information)

![Seasonal outdoor pool, open 10:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/6000000/5110000/5103800/5103713/ec1df230.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5110000/5103800/5103713/50405a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Building design](https://images.trvl-media.com/lodging/6000000/5110000/5103800/5103713/da05ff15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/6000000/5110000/5103800/5103713/d8e696aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hacienda Histórica Marchigüe

[](https://www.expedia.co.uk/Marchihue-Hotels-Hacienda-Historica-Marchigue.h5103713.Hotel-Information)

Marchihue

8.0/10

Very good

(13)

"An unusual place to stay. the staff were great and very helpful. Enjoyed the quiet and food"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anonymous traveller

[](https://www.expedia.co.uk/Marchihue-Hotels-Hacienda-Historica-Marchigue.h5103713.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-12&endDate=2026-01-13&regionId=6047957&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true)

## Top Santa Cruz Hotel Reviews

![TerraViña](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/08e2ca8e_y.jpg)

### TerraViña

10/10 Excellent

"Clean and spacious suite, fantastic staff and service and very picturesque location"

[](https://expedia.co.uk/San-Fernando-Hotels-TerraVina.h3775207.Hotel-Information)

![Santa Cruz Plaza](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/3fe1c8d9_y.jpg)

### Santa Cruz Plaza

10/10 Excellent

"Yes all great."

[](https://expedia.co.uk/San-Fernando-Hotels-Santa-Cruz-Plaza.h1406642.Hotel-Information)

![Hotel Cava Colchagua](https://images.trvl-media.com/lodging/10000000/9430000/9423000/9422950/47af8d73_y.jpg)

### Hotel Cava Colchagua

10/10 Excellent

"Hermosa localidad y buen servicio. "

[](https://expedia.co.uk/San-Fernando-Hotels-Hotel-Cava-Colchagua.h9422950.Hotel-Information)

## Frequently asked questions

### How much do business hotels in Santa Cruz cost?

### What are the best business hotels in Santa Cruz?

### How many business hotels are there in Santa Cruz?

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