Title: TOP Business Hotels in Santa Cruz for 2025 | Expedia.co.uk [Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d6047957.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6047957.Travel-Guide-HolidayRentals)[Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6047957.Travel-Guide-Flights)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d6047957.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6047957.Holidays-City-Breaks) ![Rows of vineyards, Santa Cruz, Chile](https://images.trvl-media.com/place/6047957/e58d3014-ef10-4c60-9e03-08890e2f5494.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Santa Cruz - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Cruz Business Hotels Tonight [8 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6047957&startDate=2025-11-08&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [9 Nov - 10 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6047957&startDate=2025-11-09&endDate=2025-11-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6047957&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6047957&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Santa Cruz Business Hotels ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/3fe1c8d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room, body treatments, hydrotherapy, body wraps](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/2713a051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/75df94bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Twin Room | 1 bedroom, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/4b01e3a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Santa Cruz Plaza Santa Cruz 8.6/10 Excellent (330) "What a gem! We enjoyed the historical building, the wonderful cuisine and comfortable room. Next time we add in massages! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catherine £116 1 Dec - 2 Dec [](https://www.expedia.co.uk/San-Fernando-Hotels-Santa-Cruz-Plaza.h1406642.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/08e2ca8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/337af1b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/7a4b1beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Living room | TV](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/f87c655e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TerraViña Santa Cruz 9.2/10 Wonderful (200) "Pretty" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katie £123 9 Nov - 10 Nov [](https://www.expedia.co.uk/San-Fernando-Hotels-TerraVina.h3775207.Hotel-Information) ![Seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/afe65d1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/3c454a0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/d646bdcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self-parking](https://images.trvl-media.com/lodging/19000000/18060000/18057500/18057456/e7b99456.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Perla Hotel Santa Cruz 9.2/10 Wonderful (99) "Excellent customer service, brand new facilities and delicious breakfast. The hotel staff were genuinely helpful and really made us feel like home! This is the kind of hotel we would gladly come back to when visiting Santa Cruz." ![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg) Anonymous traveller [](https://www.expedia.co.uk/San-Fernando-Hotels-La-Perla-Hotel.h18057456.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/3000000/2960000/2959500/2959484/e99bf923.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/3000000/2960000/2959500/2959484/e7b15bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Library](https://images.trvl-media.com/lodging/3000000/2960000/2959500/2959484/ea8292f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/3000000/2960000/2959500/2959484/04ef74c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Boutique Vendimia Premium Santa Cruz 9.2/10 Wonderful (135) "It’s nice, very close to main atractions such as the Casino, and good restaurants are at walking distance, very safe , I would definitely come back" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) RODOLFO £93 9 Nov - 10 Nov [](https://www.expedia.co.uk/San-Fernando-Hotels-Hotel-Boutique-Vendimia-Premium.h2959484.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/30000000/29060000/29053800/29053727/10d3ee66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/30000000/29060000/29053800/29053727/9d478df1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/30000000/29060000/29053800/29053727/2f8bdbfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/30000000/29060000/29053800/29053727/4caf0d4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Ontiveros San Fernando 9.6/10 Exceptional (21) "Amplia y comoda habitacion. Personal de recepcion muy amable y colaborador " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Eileen [](https://www.expedia.co.uk/San-Fernando-Hotels-Hotel-Ontiveros.h29053727.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/88000000/87720000/87715000/87714974/8ef18f8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/88000000/87720000/87715000/87714974/af54bde9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/88000000/87720000/87715000/87714974/743ff8ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Studio Suite | In-room safe, desk, laptop workspace, travel cot](https://images.trvl-media.com/lodging/88000000/87720000/87715000/87714974/73ef783a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Boutique Raices Curicó 9.6/10 Exceptional (37) "Pleasant hotel, small and well-run, centrally located." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) francois £81 30 Nov - 1 Dec [](https://www.expedia.co.uk/Curico-Hotels-Hotel-Boutique-Raices.h87714974.Hotel-Information) ![Seasonal outdoor pool, open 10:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/6000000/5110000/5103800/5103713/ec1df230.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/6000000/5110000/5103800/5103713/d8e696aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/6000000/5110000/5103800/5103713/da05ff15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5110000/5103800/5103713/50405a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hacienda Histórica Marchigüe Marchihue 8.0/10 Very good (13) "A propriedade é muito bonita … está precisando de reparos e manutenção em toda ela … o quarto , espaçoso , com visual bonito . Porém , necessitando de muitos reparos. Os funcionários e o serviço , impecáveis !!! Nota 10! Para toda a equipe. Desde o checkin , no restaurante , na recepção , atenciosos , gentis . Precisa de um certo investimento !!! " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Adriana [](https://www.expedia.co.uk/Marchihue-Hotels-Hacienda-Historica-Marchigue.h5103713.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-22&endDate=2025-11-23®ionId=6047957&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Cruz Hotel Reviews ![Hotel Cava Colchagua](//images.trvl-media.com/lodging/10000000/9430000/9423000/9422950/47af8d73_y.jpg) ### Hotel Cava Colchagua 10/10 Excellent "Hermosa localidad y buen servicio. " [](https://expedia.co.uk/San-Fernando-Hotels-Hotel-Cava-Colchagua.h9422950.Hotel-Information) ![TerraViña](//images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/08e2ca8e_y.jpg) ### TerraViña 10/10 Excellent "We were greeted by Rosita who was the most lovely hostess ever. She had our rooms ready early and adjusted to our requests. She ALSO made a Dr appointment for one of our party at a great local clinic. AND she let me park my car there for a few days while we made our trip to ski in Chillan. Rosita went over and above our expected hospitality. And her English was amazing. We WILL be back. " [](https://expedia.co.uk/San-Fernando-Hotels-TerraVina.h3775207.Hotel-Information) ![Santa Cruz Plaza](//images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/3fe1c8d9_y.jpg) ### Santa Cruz Plaza 10/10 Excellent "The hotel truly shines with its exceptional cleanliness and a refined design that takes inspiration from the Chilean countryside" [](https://expedia.co.uk/San-Fernando-Hotels-Santa-Cruz-Plaza.h1406642.Hotel-Information) ## Frequently asked questions ### How much do business hotels in Santa Cruz cost? > You can expect to pay between and per night for business hotels in Santa Cruz. Top deals on properties that are suitable for work-related guests are a few clicks away on Expedia. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### What are the best business hotels in Santa Cruz? > Santa Cruz has multiple business hotels with a total average guest review rating of . One of the most popular is [TerraViña](https://www.expedia.co.uk/San-Fernando-Hotels-TerraVina.h3775207.Hotel-Information). Get the job done from this 3-star option, which includes an attached winery and a garden. Many corporate travellers also recommend [Santa Cruz Plaza](https://www.expedia.co.uk/San-Fernando-Hotels-Santa-Cruz-Plaza.h1406642.Hotel-Information). It has a 4-star rating and amenities such as a steam room and a sauna. ### How many business hotels are there in Santa Cruz? > Santa Cruz has hotels that accommodate business travellers. Whether you're looking for a location close to the city centre or conveniences such as conference rooms and workspaces, you'll find a well-suited property on Expedia. ### Are there any family-friendly hotels in Santa Cruz that are also business friendly? > If you're taking the family to Santa Cruz but also need to work remotely, consider [TerraViña](https://www.expedia.co.uk/San-Fernando-Hotels-TerraVina.h3775207.Hotel-Information). This 3-star stay features handy amenities like a swimming pool and complimentary breakfast. [Hotel Boutique Solaz Bella Vista de Colchagua](https://www.expedia.co.uk/San-Fernando-Hotels-Hotel-Boutique-Solaz-Bella-Vista-De-Colchagua.h4248321.Hotel-Information) is another pick that's ideal for both leisure and business guests. It has a 3-star rating and conveniences such as complimentary breakfast and childcare services. Santa Cruz has plenty of family-friendly attractions to check out when you've finished work. Take the kids on an excursion to [Museo de Colchagua](https://www.expedia.co.uk/Museo-De-Colchagua-Santa-Cruz.d6099456.Attraction) and [Hacienda El Huique](https://www.expedia.co.uk/Hacienda-El-Huique-Palmilla.d6099458.Attraction). ### Why book your business hotel in Santa Cruz with Expedia? > At Expedia, we make it our job to help you choose a suitable stay at the right price. From 5-star corporate-friendly escapes to affordable motor inns filled with all the amenities you need, you'll have your next work trip arranged in a few simple clicks. ### How can I find cheap business hotels in Santa Cruz? > When work takes you on the road in Santa Cruz, our "business friendly" filter will help you find the ideal hotel. From included breakfast and free WiFi to concierge services and conference spaces, they come with the amenities you need to be productive. Another tip? Narrow your search by your budget and preferred star rating to see the most affordable options. ### What is there to do in Santa Cruz near my business hotel? > Whatever your interests, Santa Cruz has tons of things to keep you entertained. [Lapostolle Clos Apalta Winery](https://www.expedia.co.uk/Lapostolle-Clos-Apalta-Winery-Santa-Cruz.d553248621532463283.Attraction), [MontGras Winery](https://www.expedia.co.uk/MontGras-Winery-Palmilla.d6283554.Attraction) and [Laura Hartwig Winery](https://www.expedia.co.uk/Laura-Hartwig-Winery-Santa-Cruz.d553248621532463280.Attraction) are on many visitors' sightseeing itineraries. Don't leave without exploring [Museo de Colchagua](https://www.expedia.co.uk/Museo-De-Colchagua-Santa-Cruz.d6099456.Attraction), [Hacienda El Huique](https://www.expedia.co.uk/Hacienda-El-Huique-Palmilla.d6099458.Attraction) and [Casino Colchagua](https://www.expedia.co.uk/Casino-Colchagua-Santa-Cruz.d553248621532463282.Attraction) either. With Expedia's business hotel deals, you can see more renowned attractions like these with the money you save.