Title: Santa Cruz Travel Guide: Best of Santa Cruz, O'Higgins Region Travel 2026 | Expedia.co.uk [Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d6047957.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6047957.Travel-Guide-HolidayRentals)[Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6047957.Travel-Guide-Flights)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d6047957.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6047957.Holidays-City-Breaks) # Santa Cruz Travel Guide ## Tourist Guide ![Rows of vineyards, Santa Cruz, Chile](https://images.trvl-media.com/place/6047957/e58d3014-ef10-4c60-9e03-08890e2f5494.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Rows of vineyards, Santa Cruz, Chile](https://images.trvl-media.com/place/6047957/e58d3014-ef10-4c60-9e03-08890e2f5494.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Chilean Wine - Vineyards - Chile](https://images.trvl-media.com/place/6047957/cdb9eb51-9321-43be-93a7-cc61dddb971b.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Vineyards in the Colchagua Valley - Chile](https://images.trvl-media.com/place/6047957/a319a664-b489-4d8b-88b2-e380b1fe83ec.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Amazing place to relax and enjoy the view after tasting good wine...](https://images.trvl-media.com/place/6047957/3f6f573a-78af-41a2-967b-d9399720ea19.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santa Cruz Things to do - Top hotels in Santa Cruz - Top Holiday Rentals in Santa Cruz ![Santa Cruz Plaza](https://images.trvl-media.com/lodging/2000000/1410000/1406700/1406642/3fe1c8d9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Santa Cruz Plaza Plaza De Armas 286 Santa Cruz O'Higgins £101 1 Mar - 2 Mar Stay at this spa hotel in Santa Cruz. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular attractions ... 8.6/10 Excellent! (341 reviews) Very clean and staff very courteous Reviewed on 4 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=01%2F03%2F2026&endDate=02%2F03%2F2026&selected=1406642&PinnedHotelID=1406642&HadPinnedHotel=true®ionId=6047957) ![Hotel Cava Colchagua](https://images.trvl-media.com/lodging/10000000/9430000/9423000/9422950/47af8d73_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Cava Colchagua Barreales´s Way Santa Cruz O'Higgins Stay at this spa hotel in Santa Cruz. Enjoy free breakfast, a full-service spa and an on-site winery. Popular attractions Laura Hartwig Winery and Colchagua ... 8.8/10 Excellent! (171 reviews) Hermosa localidad y buen servicio. Reviewed on 24 Oct 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=21%2F02%2F2026&endDate=22%2F02%2F2026&selected=9422950&PinnedHotelID=9422950&HadPinnedHotel=true®ionId=6047957) [](https://expedia.co.uk/Hotel-Search?startDate=21%2F02%2F2026&endDate=22%2F02%2F2026&selected=9422950&PinnedHotelID=9422950&HadPinnedHotel=true®ionId=6047957) ![TerraViña](https://images.trvl-media.com/lodging/4000000/3780000/3775300/3775207/08e2ca8e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### TerraViña Camino Los Boldos S/n Santa Cruz O'Higgins Fully refundableReserve now, pay when you stay £100 10 Feb - 11 Feb Stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Laura Hartwig Winery and Plaza de ... 9/10 Wonderful! (208 reviews) Great location, friendly staff . Reviewed on 22 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=10%2F02%2F2026&endDate=11%2F02%2F2026&selected=3775207&PinnedHotelID=3775207&HadPinnedHotel=true®ionId=6047957) [See all 57 properties in Santa Cruz](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=08%2F02%2F2026&endDate=09%2F02%2F2026®ionId=6047957) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Colchagua Tiny Lodge](https://images.trvl-media.com/lodging/113000000/112020000/112019700/112019659/a6261078_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Colchagua Tiny Lodge I-350 kilometro 4,5 Santa Cruz O'Higgins Stay at this cabin in Santa Cruz. Enjoy free Wi-Fi, free parking and private hot tubs. Popular attractions Lapostolle Clos Apalta Winery and Bodega Viña Viu ... 9.8/10 Exceptional! (7 reviews) Very cute spot, extremely easy to access wineries, breakfast basket delicious and whatever time you need. Hot tub was wood fired and heated daily by staff but was actually too hot for use to use for long. A little too close to the road to feel very remote and we had a horrible time trying to sleep ... Reviewed on 4 Jan 2026 [](https://expedia.co.uk/Santa-Cruz-Hotels-Colchagua-Tiny-Lodge.h112019659.Hotel-Information) ![Apalta Lofts, enjoy the vineyards in front of the vineyards](https://images.trvl-media.com/lodging/120000000/120000000/119996000/119995983/b7e7e422_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Apalta Lofts, enjoy the vineyards in front of the vineyards El Condor O'Higgins Stay at this cabin in Santa Cruz. Enjoy air conditioning and a hot tub. Popular attractions Lapostolle Clos Apalta Winery and Colchagua Campo y Vino are located ... [](https://expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h119995983.Hotel-Information) ![The ambush. Field and comfort](https://images.trvl-media.com/lodging/39000000/38120000/38118300/38118253/b9cfe331_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The ambush. Field and comfort Santa Cruz Región del Libertador Gral. Bernardo O’Higgins Stay at this holiday home in Santa Cruz. Enjoy free breakfast, a garden and patios. Popular attractions Laura Hartwig Winery and Plaza de Armas are located ... [](https://expedia.co.uk/Santa-Cruz-Hotels-The-Ambush-Field-And-Comfort.h38118253.Hotel-Information) [See all properties in Santa Cruz](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6047957&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa Cruz hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6047957&startDate=2026-02-07&endDate=2026-02-08)[7 Feb - 8 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6047957&startDate=2026-02-07&endDate=2026-02-08) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6047957&startDate=2026-02-08&endDate=2026-02-09)[8 Feb - 9 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6047957&startDate=2026-02-08&endDate=2026-02-09) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6047957&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026)[13 Feb - 15 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6047957&startDate=13%2F02%2F2026&endDate=15%2F02%2F2026) ### Popular places to visit #### Lapostolle Clos Apalta Winery 4.5/5(3 reviews) You can enjoy a tasting or tour at Lapostolle Clos Apalta Winery during your travels to Santa Cruz. While in this relaxing area, you can savour the wineries and restaurants. [](https://expedia.co.uk/Lapostolle-Clos-Apalta-Winery-San-Fernando.d553248621532463283.Attraction) #### Casino Colchagua Why not roll the dice with a visit to Casino Colchagua during your travels in Santa Cruz? While in this relaxing area, you can savour the wineries and restaurants. [](https://expedia.co.uk/Casino-Colchagua-San-Fernando.d553248621532463282.Attraction) #### Colchagua Campo y Vino Enjoy an outing to Colchagua Campo y Vino during your stay in Santa Cruz. While in this relaxing area, you can savour the wineries and restaurants. [](https://expedia.co.uk/Colchagua-Campo-Y-Vino-San-Fernando.d553248621532463281.Attraction) #### Laura Hartwig Winery 5/5(1 review) You can enjoy a tasting or tour at Laura Hartwig Winery during your travels to Santa Cruz. While in this relaxing area, you can savour the wineries and restaurants. [](https://expedia.co.uk/Laura-Hartwig-Winery-San-Fernando.d553248621532463280.Attraction) #### Bodega Viña Viu Manent You can enjoy a tasting or tour at Bodega Viña Viu Manent during your travels to Santa Cruz. While in this relaxing area, you can savour the wineries and restaurants. [](https://expedia.co.uk/Bodega-Vina-Viu-Manent-Santa-Cruz.d873855731647115264.Attraction) #### Plaza de Armas Find out about the history of Santa Cruz when you take a trip to Plaza de Armas. While in this relaxing area, you can savour the wineries and restaurants. [](https://expedia.co.uk/Plaza-De-Armas-San-Fernando.d6099454.Attraction) ### Things to do ![Peralillo Chapel](https://mediaim.expedia.com/localexpert/45717765/f00a01c2-cae4-419c-98f7-0c1d94b893a8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Moment Tour Tasting £16 per adult [](https://expedia.co.uk/things-to-do/moment-tour-tasting.a45717765.activity-details) ![Customers](https://mediaim.expedia.com/localexpert/45705412/49ec69fb-197e-4efb-a2f3-02236449f694.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Moment Premium Tasting Tour £29 per adult [](https://expedia.co.uk/things-to-do/moment-premium-tasting-tour.a45705412.activity-details) ![Make Your Own Wine & Guided Vineyard Tour ](https://mediaim.expedia.com/localexpert/46200977/2edfdc20-7979-4beb-b97e-2ba00246939c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Make Your Own Wine & Guided Vineyard Tour £35 per adult [](https://expedia.co.uk/things-to-do/make-your-own-wine-guided-vineyard-tour.a46200977.activity-details) ![Viu Manet vineyard](https://mediaim.expedia.com/localexpert/2681376/c4fc5f62-e4b2-4f25-b1c1-59373d0b0b80.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Colchagua Valley Viñas Viu Manet and Montes Alfha £283 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/colchagua-valley-vinas-viu-manet-and-montes-alfha.a2681376.activity-details) ![Biking Colchagua Wine Valley](https://mediaim.expedia.com/localexpert/48848543/dffd567d-ddc5-4d49-b668-cbc0314a6200.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Biking Colchagua Wine Valley (4 DAYS) £2,525 per adult [](https://expedia.co.uk/things-to-do/biking-colchagua-wine-valley-4-days.a48848543.activity-details) ![Viu Manent tour](https://mediaim.expedia.com/localexpert/46790586/8281bde6-a8fc-407d-ba24-3d5b37d230c6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Viu Manent and Montes Winery, Colchagua Valley from semi-private £209 per adult [](https://expedia.co.uk/things-to-do/viu-manent-and-montes-winery.a46790586.activity-details) [See all activities in Santa Cruz](https://expedia.co.uk/Things-To-Do-In-Santa-Cruz.d6047957.Travel-Guide-Activities) ## Cities near Santa Cruz ![Discovered my favorite grape in the vineyards of Chile. What grape is it? Carménère #Culture](https://images.trvl-media.com/place/3000006362/d1f31aae-7d9f-4840-923c-a5919fefcb2b.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Lolol - Cities near Santa Cruz - Places of interest [Nancagua](https://expedia.co.uk/Nancagua.dx3000006338)[Lolol](https://expedia.co.uk/Lolol.dx3000006362) - [Hacienda El Huique ](https://expedia.co.uk/Hacienda-El-Huique-Palmilla.d6099458.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app