Sant' Ambrogio Holidays from £234

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Your Sant Ambrogio Holiday

Make planning your travels stress-free by booking a holiday package to Sant Ambrogio. We'll handle all the details, so you can concentrate on soaking up everything this neighbourhood has to offer. Some nearby attractions to check out during your trip to Sant Ambrogio include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Stop dreaming and start doing. When it's time to lock in your dream holiday to Sant Ambrogio, Expedia will help you get there.

Price found within the past 48 hours. Click for updated prices.
Aurum Uffizi

Aurum Uffizi

Historic Centre of Florence
Save 100% on your flight
£234
per person
4 Dec - 7 Dec
found 1 day ago
Return flight included
London (LON) to Florence (FLR)
7.6/10 Good! (1,001 reviews)
Great location, clean room and wonderful staff

Reviewed on 9 Sept 2026

EXE Toscana

EXE Toscana

Mugnano
Save 100% on your flight
£986
per person
26 Oct - 31 Oct
found 3 hours ago
Return direct flight included
London (LHR) to Florence (FLR)
8.4/10 Very good! (853 reviews)
The hotel is located very near the autostrade and outside the walled city. Access is easy and direct. Staff were multi lingual and friendly. English was not a problem. Parking is free. Breakfast is served as a buffet and you do need to notify if you intend to partake. It is 13euros. There is a good variety, but it is the same every day. There is an espresso/coffee machine. Nothing available to order. Amenities. There aren’t any (like fitness room or pool). There are meeting rooms up from the lobby. The restaurant isn’t open beyond breakfast and they only offer the buffet. The bar is only open weekdays in the evening. There is a supermarket next door and a McDonald’s around the corner, both easy walking distance. A bit further are a couple of sit-down restaurants and a very good pizzeria. There are more pizzerias here than Starbucks in Seattle! We would stay there again. The lack of amenities isn’t important to us.

Reviewed on 2 Aug 2026

Palace Hotel

Palace Hotel

Marco Polo
Save 100% on your flight
£560
per person
26 Oct - 31 Oct
found 3 hours ago
Return direct flight included
London (LHR) to Florence (FLR)
9/10 Wonderful! (139 reviews)
Hotel Centro

Hotel Centro

Historic Centre of Florence
Save 100% on your flight
£427
per person
19 Oct - 23 Oct
found 20 hours ago
Return flight included
London (LON) to Florence (FLR)
8.2/10 Very good! (62 reviews)
Dimora Palanca Boutique & SPA

Dimora Palanca Boutique & SPA

Historic Centre of Florence
Save 100% on your flight
£896
per person
15 Oct - 20 Oct
found 2 hours ago
Return flight included
London (LGW) to Florence (FLR)
9.2/10 Wonderful! (69 reviews)
The accommodation very much complimented our wonderful experience and love for Florence. Our room, the connected amenities and the wonderful attentive service made our trip very memorable.

Reviewed on 7 Sept 2026

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most. Learn more about Sant' Ambrogio
A river with buildings on the right bank.

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

A historic building with ornate carvings and statues, featuring large wooden doors and steps leading up to it.

Duomo

Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Piazza del Duomo or Piazza di Santa Maria Novella while you're exploring the neighbourhood.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

A stone bridge with green shutters over a river.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

A bustling European square with historic buildings, shops, and a prominent clock tower.

Santa Croce

Santa Croce is known for its interesting museums, and you can plan a trip to Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top hotels in Sant' Ambrogio

Hotel Regency

Hotel Regency

Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
£484
11 Oct - 12 Oct
includes taxes & fees
Hotel Regency
Hotel Bodoni

Hotel Bodoni

Via Martiri del Popolo, 27 Florence FI
£100
27 Sept - 28 Sept
includes taxes & fees
8.2/10 Very good! (867 reviews)
"This is a clear case of getting what you paid for as the rates in this hotel was cheap so we ended up very disappointed. My party occupied 6 rooms and only 2 had complete baths. The others had only a partition in the washroom area with water escaping into the room when a bath was taken. There is ..."

Reviewed on 9 Sept 2026

Hotel Bodoni
Hotel Bavaria

Hotel Bavaria

Borgo Albizi 26 Florence FI
£94
14 Sept - 15 Sept
includes taxes & fees
8.2/10 Very good! (454 reviews)
"We really enjoyed our stay at Hotel Bavaria! The rooms were clean and organized, the staff were extremely helpful and provided lots of recommendations for activities and food. The best part of this hotel is by far the location everything you could need is in walking distance! We would definitely ..."

Reviewed on 9 Sept 2026

Hotel Bavaria
See all 534 properties in Sant' Ambrogio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sant Ambrogio travel package cost?
From as little as £234, you can handcraft your own Sant Ambrogio package. Simply bundle hotels, flights and rental cars and we'll reward you with discounts.
If I'm not able to travel, can I cancel my Sant Ambrogio travel package?
Yes, you can. We totally understand that things don't always go to plan, so we're here to help if you need to make changes to your Sant Ambrogio travel package. You may be able to cancel or change your itinerary at no cost if you've booked within 24 hours. Your airline, hotel or car rental company may impose a fee if you booked more than 24 hours ago. Head to our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.
How do I get a cheap travel package to Sant' Ambrogio?
Combining your flight and hotel with Expedia won't just save valuable time — it'll save you dollars too. A Sant' Ambrogio travel package makes it a breeze to arrange your ideal trip. With more than 550 airlines around the world to pick from, finding flights that fit your schedule won't be hard. In addition to that, we have over 1,000,000 hotel options globally to take your pick of. Now that's what we call choice. Whatever your budget, Expedia can show you the world.
Does Expedia offer Book Now, Pay Later Sant' Ambrogio holidays?
Expedia has teamed up with online lender Klarna to make booking your next break easier on the purse strings. Paying by instalment means you can spread the costs of your next dream escape, leaving you with more cash to splash while you're away. Klarna has several payment plans to pick from, so you're sure to find one that works with your budget. Consider these flexible payment options:
  • Pay monthly holidays: Make your holiday dreams come true sooner with Klarna's monthly instalment plans. If making small repayments each month sounds right for you, choose this option at checkout.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay for your holiday over multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to hit that "book now" button, opt for a low deposit holiday payment plan from Klarna.
Where should I stay in Sant Ambrogio?
Make sightseeing easy by staying close to Sant Ambrogio's fantastic attractions. Ponte Vecchio and Cathedral of Santa Maria del Fiore are two which top many visitors' bucket lists.
What are the top hotels in Sant Ambrogio?
Get your trip off to a fantastic start by reserving a room at Hotel LOrologio. It's one of most sought-after hotels in Sant Ambrogio. Another top option is Palazzo Graziani.
How far in advance should I book my Sant Ambrogio holiday?
Travellers are normally able to look up international flights on Expedia within 12 months of departure. Booking at the last minute? With a little bit of luck, it's still possible to purchase a cheap ticket only weeks before your journey.
What does an Expedia Sant Ambrogio travel package include?
It all depends on what type of getaway you're contemplating. Sant Ambrogio travel deals can include car rentals, flights and hotels. You can mix and match to find the bundle that suits your budget and style. You can also add on experiences and activities after you've booked to score even bigger discounts.
What should I know before booking a Sant Ambrogio travel package?
Whether it's relaxation or adventure you're seeking, a Sant Ambrogio travel package lets you plan your escape your way. Plus, you'll get access to great discounts when you combine your hotel with your flights and rental car. The more you bundle, the more you'll save!
Can I choose my airline with a Sant Ambrogio Expedia travel package?
Yes, you sure can. Expedia has access to more than 550 partner airlines globally, so choose the carrier that's a good fit for your budget and travelling style.

Stay near popular Sant' Ambrogio attractions

Great Synagogue of Florence

9.0/10 (6 reviews)
Great Synagogue of Florence is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed art galleries in this vibrant area.
See properties

Church of Sant'Ambrogio

9.0/10 (13 reviews)
After visiting Church of Sant'Ambrogio, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or visit the notable monuments in this vibrant area.
See properties

Mercato di Sant'Ambrogio

10.0/10 (1 review)
You can find the perfect gifts to bring home at Mercato di Sant'Ambrogio during your visit to Florence. Discover the fascinating museums and notable monuments in this vibrant area.
See properties

Piazza Massimo D'Azeglio

Find out about the history of Florence when you take a trip to Piazza Massimo D'Azeglio. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
See properties

Church of Santa Maria Maddalena dei Pazzi

8.0/10 (2 reviews)
You can learn about the history of Florence when you stop by Church of Santa Maria Maddalena dei Pazzi. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
See properties

Piazza Donatello

You can learn about the history of Florence with a visit to Piazza Donatello. Stroll along the riverfront or visit the notable monuments in this vibrant area.
See properties

Jewish Museum

8.8/10 (16 reviews)
You can study the exhibits at Jewish Museum, a museum with a story of its own, during your holiday in Florence. Experience the fascinating museums and acclaimed art galleries in this vibrant area.
See properties

FiesoleBike Day Tours

You can take time to visit FiesoleBike Day Tours during your travels to Florence. Stroll along the riverfront or experience the acclaimed art galleries in this vibrant area.
See properties

Things to do

City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

£21
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Florence: Pasta Cooking Class with Unlimited Wine

Florence: Pasta Cooking Class with Unlimited Wine

£14
per adult
94% of travellers recommend
Florence: Pasta Cooking Class with Unlimited Wine
Best of Florence Tour with Fast Track Accademia & Duomo

Best of Florence Tour with David at Accademia & Duomo (with VIP option)

£74
per adult
96% of travellers recommend
Best of Florence Tour with David at Accademia & Duomo (with VIP option)
See all activities in Florence

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.