Sant' Ambrogio Holidays from £316

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Your Sant Ambrogio Holiday

Make planning your travels stress-free by booking a holiday package to Sant Ambrogio. We'll handle all the details, so you can concentrate on soaking up everything this neighbourhood has to offer. Some nearby attractions to check out during your trip to Sant Ambrogio include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Stop dreaming and start doing. When it's time to lock in your dream holiday to Sant Ambrogio, Expedia will help you get there.

Price found within the past 48 hours. Click for updated prices.
Alfieri9

Alfieri9

3 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was £473, price is now £316 per person
£316
per person
24 Apr - 26 Apr
found 1 day ago
Return flight included
Manchester (MAN) to Florence (FLR)
9.6/10 Exceptional! (156 reviews)
Hotel was in a nice quiet neighborhood, but still only a short walk to main attractions. The breakfast was excellent. Staff interactions were good.

Reviewed on 5 Dec 2025

The Moon Boutique Hotel & Spa

The Moon Boutique Hotel & Spa

4 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was £1,048, price is now £647 per person
£647
per person
20 Apr - 25 Apr
found 1 day ago
Return flight included
London (LGW) to Florence (FLR)
9.6/10 Exceptional! (511 reviews)
Outstanding Boutique Hotel. Friendly Multilingual Staff, Great Breakfast, beautiful and spacious room. Absolutely amazing Wellness Spa! Centrally located for easy access to all of Firenze via public transportation. 30 mins from airport. I highly recommend The Moon Hotel And Spa!

Reviewed on 23 Feb 2026

Residenza Florentia

Residenza Florentia

1 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was £771, price is now £491 per person
£491
per person
15 Apr - 18 Apr
found 1 day ago
Return flight included
London (LGW) to Florence (FLR)
8.4/10 Very Good! (46 reviews)
Location, accommodations, and communication. Simple but comfortable. A basic facilities, and nice AC, elevator, and luggage storage.

Reviewed on 12 Jun 2025

Hotel Alessandra

Hotel Alessandra

2 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was £762, price is now £500 per person
£500
per person
20 Apr - 25 Apr
found 1 day ago
Return flight included
London (LGW) to Florence (FLR)
9.2/10 Wonderful! (849 reviews)
Clean room, amazing staff, location is great

Reviewed on 2 Feb 2026

Hotel Villani

Hotel Villani

2 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was £716, price is now £481 per person
£481
per person
4 May - 7 May
found 1 day ago
Return direct flight included
Birmingham (BHX) to Florence (FLR)
8.6/10 Excellent! (464 reviews)
Room was spotless! Front desk staff was amazing, incredibly helpful. They went above and beyond I was very impressed!!

Reviewed on 19 Feb 2026

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most. Learn more about Sant' Ambrogio
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Top hotels in Sant' Ambrogio

Hotel Bavaria

Hotel Bavaria

1 out of 5
Borgo Albizi 26 Florence FI
The price is £57 per night from 4 Mar to 5 Mar
£57
4 Mar - 5 Mar
includes taxes & fees
8.2/10 Very Good! (421 reviews)
The manager was very nice and efficient. The room was spacious. Very close to the Doumo ( We could see a litte of the dome from our window.)

Reviewed on 23 Feb 2026

Hotel Bavaria
Hotel Bodoni

Hotel Bodoni

2 out of 5
Via Martiri del Popolo, 27 Florence FI
Fully refundableReserve now, pay when you stay
The price is £83 per night from 22 Mar to 23 Mar
£83
22 Mar - 23 Mar
includes taxes & fees
8.2/10 Very Good! (802 reviews)
The bathroom is a little uncomfortable but the location of the hotel is amazing, we had an amazing stay

Reviewed on 1 Mar 2026

Hotel Bodoni
Hotel Regency

Hotel Regency

5 out of 5
Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
The price is £276 per night from 4 Mar to 5 Mar
£276
4 Mar - 5 Mar
includes taxes & fees
9.4/10 Exceptional! (444 reviews)
Amazing staff, great location large rooms

Reviewed on 24 Feb 2026

Hotel Regency
See all 521 properties in Sant' Ambrogio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Sant Ambrogio travel package cost?
From as little as £316, you can handcraft your own Sant Ambrogio package. Simply bundle hotels, flights and rental cars and we'll reward you with discounts.
If I'm not able to travel, can I cancel my Sant Ambrogio travel package?
Yes, you can. We totally understand that things don't always go to plan, so we're here to help if you need to make changes to your Sant Ambrogio travel package. You may be able to cancel or change your itinerary at no cost if you've booked within 24 hours. Your airline, hotel or car rental company may impose a fee if you booked more than 24 hours ago. Head to our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.
How do I get a cheap travel package to Sant' Ambrogio?
Combining your flight and hotel with Expedia won't just save valuable time — it'll save you dollars too. A Sant' Ambrogio travel package makes it a breeze to arrange your ideal trip. With more than 550 airlines around the world to pick from, finding flights that fit your schedule won't be hard. In addition to that, we have over 1,000,000 hotel options globally to take your pick of. Now that's what we call choice. Whatever your budget, Expedia can show you the world.
Does Expedia offer Book Now, Pay Later Sant' Ambrogio holidays?
Expedia has teamed up with online lender Klarna to make booking your next break easier on the purse strings. Paying by instalment means you can spread the costs of your next dream escape, leaving you with more cash to splash while you're away. Klarna has several payment plans to pick from, so you're sure to find one that works with your budget. Consider these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams come true sooner with Klarna's monthly instalment plans. If making small repayments each month sounds right for you, choose this option at checkout.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay for your holiday over multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to hit that "book now" button, opt for a low deposit holiday payment plan from Klarna.

Where should I stay in Sant Ambrogio?
Make sightseeing easy by staying close to Sant Ambrogio's fantastic attractions. Ponte Vecchio and Cathedral of Santa Maria del Fiore are two which top many visitors' bucket lists.
What are the top hotels in Sant Ambrogio?
Get your trip off to a fantastic start by reserving a room at Hotel LOrologio. It's one of most sought-after hotels in Sant Ambrogio. Another top option is Palazzo Graziani.
How far in advance should I book my Sant Ambrogio holiday?
Travellers are normally able to look up international flights on Expedia within 12 months of departure. Booking at the last minute? With a little bit of luck, it's still possible to purchase a cheap ticket only weeks before your journey.
What does an Expedia Sant Ambrogio travel package include?
It all depends on what type of getaway you're contemplating. Sant Ambrogio travel deals can include car rentals, flights and hotels. You can mix and match to find the bundle that suits your budget and style. You can also add on experiences and activities after you've booked to score even bigger discounts.
What should I know before booking a Sant Ambrogio travel package?
Whether it's relaxation or adventure you're seeking, a Sant Ambrogio travel package lets you plan your escape your way. Plus, you'll get access to great discounts when you combine your hotel with your flights and rental car. The more you bundle, the more you'll save!
Can I choose my airline with a Sant Ambrogio Expedia travel package?
Yes, you sure can. Expedia has access to more than 550 partner airlines globally, so choose the carrier that's a good fit for your budget and travelling style.

Popular places to visit

Piazza Massimo D'Azeglio

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Piazza Massimo D'Azeglio

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78% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.