Sant' Ambrogio Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your Sant Ambrogio Holiday

Make planning your travels stress-free by booking a holiday package to Sant Ambrogio. We'll handle all the details, so you can concentrate on soaking up everything this neighbourhood has to offer. Some nearby attractions to check out during your trip to Sant Ambrogio include Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Stop dreaming and start doing. When it's time to lock in your dream holiday to Sant Ambrogio, Expedia will help you get there.

Price found within the past 48 hours. Click for updated prices.
  • Quadruple Room | Premium bedding, minibar, in-room safe, blackout curtains
    Aug 26 - Aug 30

    Aurum Firenze + Flight

    Historic Centre of Florence
    4 nights
    4.0 star property
    7.6/10 - Good (1,025 reviews)
    "Très bien situé, tout près du centre. Terrasse pour le déjeuner très agréable! Chambre bien aménagée et pratique."
    Reviewed June 5, 2026
    Return • Birmingham (BHX) - Rome (FCO)
    BHX - FCO • Direct FCO - BHX • Direct
    Save 100% on your flight
    £631
    £353
    per traveller
    found 2 days ago
    Aurum Firenze
  • Triple Room | Bathroom | Shower, rainfall showerhead, free toiletries, hair dryer
    Aug 30 - Sep 6

    Aurum Uffizi + Flight

    Historic Centre of Florence
    7 nights
    4.0 star property
    7.6/10 - Good (1,012 reviews)
    "The hotel was conveniently located, and the service was good. Overall, it was a pleasant stay. However, I hope the hotel improves its Wi-Fi coverage, as the connection can become unstable when multiple guests are accessing the network."
    Reviewed June 5, 2026
    Return • Birmingham (BHX) - Rome (FCO)
    BHX - FCO • Direct FCO - BHX • Direct
    £1,045
    £400
    per traveller
    found 2 days ago
    Aurum Uffizi
  • Seasonal outdoor pool, pool umbrellas, pool loungers
    Jul 31 - Aug 7

    Rocca Palazzaccio + Flight

    Impruneta
    7 nights
    3.0 star property
    9.0/10 - Wonderful (14 reviews)
    "The apartment is great as is the pool, and marco who looks after it is very nice. There is absolutely nothing in the area, you need to get the 37 bus to Florence if you want to eat or drink anything. The co-op is closed from 8pm and all day Sunday, the only restaurant closed down recently so at 7:30pm on a Saturday we found ourselves with nowhere whatsoever to eat. We had bread that we bought earlier at the shop, and on Sunday we ate in Florence before getting the bus back - be careful, half of..."
    Reviewed August 24, 2023
    Return • London (LGW) - Florence (FLR)
    LGW - FLR • Direct FLR - LGW • Direct
    Save 100% on your flight
    £1,608
    £959
    per traveller
    found 2 days ago
    Rocca Palazzaccio
  • Front of property
    Aug 29 - Sep 2

    Villa Cora + Flight

    Oltrarno
    4 nights
    5.0 star property
    9.8/10 - Exceptional (475 reviews)
    Return • London (LGW) - Florence (FLR)
    LGW - FLR • Direct FLR - LHR • Direct
    Save 100% on your flight
    £2,560
    £1,555
    per traveller
    found 17 hours ago
    Villa Cora
  • Deluxe Room | Terrace/patio
    Aug 14 - Aug 28

    Hotel Villa Liana + Flight

    Historic Centre of Florence
    14 nights
    3.0 star property
    8.6/10 - Excellent (354 reviews)
    Return • London (LHR) - Florence (FLR)
    LHR - FLR • 1 stop FLR - LHR • 1 stop
    Save 100% on your flight
    £1,283
    £782
    per traveller
    found 1 day ago
    Hotel Villa Liana

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most. Learn more about Sant' Ambrogio
Historic Centre of Florence

Historic Centre of Florence

9 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Top hotels in Sant' Ambrogio

Hotel Regency

Hotel Regency

5 out of 5
Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
The price is £426 per night from 10 Jul to 11 Jul
£426
10 Jul - 11 Jul
includes taxes & fees
9.4/10 Exceptional! (450 reviews)
"The breakfast was delicious, a wide variety. Service was excellent, quite responsive and attentive staff."

Reviewed on 12 Apr 2026

Hotel Regency
Hotel Bavaria

Hotel Bavaria

1 out of 5
Borgo Albizi 26 Florence FI
Fully refundableReserve now, pay when you stay
The price is £93 per night from 28 Jun to 29 Jun
£93
28 Jun - 29 Jun
includes taxes & fees
8.2/10 Very Good! (440 reviews)
"The property itself is wonderful—very clean, in a perfect location, and the room was exceptionally spacious for our family of two adults and two teenagers. We truly enjoyed our stay and found the accommodations comfortable and well-maintained. The only downside was our experience with the staff. ..."

Reviewed on 8 Jun 2026

Hotel Bavaria
Hotel Bodoni

Hotel Bodoni

2 out of 5
Via Martiri del Popolo, 27 Florence FI
The price is £93 per night from 3 Jul to 4 Jul
£93
3 Jul - 4 Jul
includes taxes & fees
8.2/10 Very Good! (833 reviews)
"Great location, clean and welcoming. It’s easy to get in, just click labeled button and they’ll let you in. Lovely rooftop, breakfast, etc."

Reviewed on 31 May 2026

Hotel Bodoni
See all 532 properties in Sant' Ambrogio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Sant Ambrogio travel package cost?
From as little as , you can handcraft your own Sant Ambrogio package. Simply bundle hotels, flights and rental cars and we'll reward you with discounts.
If I'm not able to travel, can I cancel my Sant Ambrogio travel package?
Yes, you can. We totally understand that things don't always go to plan, so we're here to help if you need to make changes to your Sant Ambrogio travel package. You may be able to cancel or change your itinerary at no cost if you've booked within 24 hours. Your airline, hotel or car rental company may impose a fee if you booked more than 24 hours ago. Head to our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.
How do I get a cheap travel package to Sant' Ambrogio?
Combining your flight and hotel with Expedia won't just save valuable time — it'll save you dollars too. A Sant' Ambrogio travel package makes it a breeze to arrange your ideal trip. With more than 550 airlines around the world to pick from, finding flights that fit your schedule won't be hard. In addition to that, we have over 1,000,000 hotel options globally to take your pick of. Now that's what we call choice. Whatever your budget, Expedia can show you the world.
Does Expedia offer Book Now, Pay Later Sant' Ambrogio holidays?
Expedia has teamed up with online lender Klarna to make booking your next break easier on the purse strings. Paying by instalment means you can spread the costs of your next dream escape, leaving you with more cash to splash while you're away. Klarna has several payment plans to pick from, so you're sure to find one that works with your budget. Consider these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams come true sooner with Klarna's monthly instalment plans. If making small repayments each month sounds right for you, choose this option at checkout.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay for your holiday over multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to hit that "book now" button, opt for a low deposit holiday payment plan from Klarna.

Where should I stay in Sant Ambrogio?
Make sightseeing easy by staying close to Sant Ambrogio's fantastic attractions. Ponte Vecchio and Cathedral of Santa Maria del Fiore are two which top many visitors' bucket lists.
What are the top hotels in Sant Ambrogio?
Get your trip off to a fantastic start by reserving a room at Hotel LOrologio. It's one of most sought-after hotels in Sant Ambrogio. Another top option is Palazzo Graziani.
How far in advance should I book my Sant Ambrogio holiday?
Travellers are normally able to look up international flights on Expedia within 12 months of departure. Booking at the last minute? With a little bit of luck, it's still possible to purchase a cheap ticket only weeks before your journey.
What does an Expedia Sant Ambrogio travel package include?
It all depends on what type of getaway you're contemplating. Sant Ambrogio travel deals can include car rentals, flights and hotels. You can mix and match to find the bundle that suits your budget and style. You can also add on experiences and activities after you've booked to score even bigger discounts.
What should I know before booking a Sant Ambrogio travel package?
Whether it's relaxation or adventure you're seeking, a Sant Ambrogio travel package lets you plan your escape your way. Plus, you'll get access to great discounts when you combine your hotel with your flights and rental car. The more you bundle, the more you'll save!
Can I choose my airline with a Sant Ambrogio Expedia travel package?
Yes, you sure can. Expedia has access to more than 550 partner airlines globally, so choose the carrier that's a good fit for your budget and travelling style.

Popular places to visit

Piazza Massimo D'Azeglio

Find out about the history of Florence when you take a trip to Piazza Massimo D'Azeglio. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.

Piazza Massimo D'Azeglio

Things to do

City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

£25
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
Small-Group Wine Tasting Experience in the Tuscan Countryside

Small-Group Wine Tasting Experience in the Tuscan Countryside

£77
per adult
98% of travellers recommend
Small-Group Wine Tasting Experience in the Tuscan Countryside
Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

£20
per adult
80% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
See all activities in Florence

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.