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Our top choices for Sanctuary hotels

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
15.7 mi from Sanctuary
5.8 out of 10, (1,004 reviews)
"Staff was amazing. Rooms were clean "
United States
Brandi
The price is £51
includes taxes & fees
26 Apr - 27 Apr
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
14 mi from Sanctuary
8.8 out of 10, Excellent, (1,001 reviews)
"Room was clean and staff was fantastic "
United States
Wayne
The price is £74
includes taxes & fees
10 May - 11 May
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
14.9 mi from Sanctuary
9.2 out of 10, Wonderful, (1,384 reviews)
"Great location, clean rooms, wonderful basic breakfast and coffee, I will be back again."
United States
Eduardo
The price is £81
includes taxes & fees
5 May - 6 May
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Allure Suites

Allure Suites
3.0 star property
16.9 mi from Sanctuary
7.6 out of 10, Good, (1,003 reviews)
"We had a great stay,friendly staff, etc...."
United States
Dale
The price is £65
includes taxes & fees
27 Apr - 28 Apr
Allure Suites

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
12.4 mi from Sanctuary
8.2 out of 10, Very good, (1,099 reviews)
"Rooms were perfect, bigger than most and very comfortable. Staff was incredibly friendly and the breakfast had a waffle maker! "
United States
Emily
The price is £81
includes taxes & fees
4 May - 5 May
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
18.7 mi from Sanctuary
8.6 out of 10, Excellent, (854 reviews)
"Nice free breakfast"
United States
Janet
The price is £77
includes taxes & fees
26 Apr - 27 Apr
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Homewood Suites by Hilton - Fort Myers

Homewood Suites by Hilton - Fort Myers
3.0 star property
19.2 mi from Sanctuary
9.2 out of 10, Wonderful, (1,017 reviews)
"Great room and the breakfast was delicious "
United States
Jackeline
The price is £95
includes taxes & fees
10 May - 11 May
Homewood Suites by Hilton - Fort Myers

Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
15.8 mi from Sanctuary
7.6 out of 10, Good, (1,003 reviews)
"The location was great for access to beaches"
United States
Shelly
The price is £66
includes taxes & fees
22 Apr - 23 Apr
Candlewood Suites Fort Myers Sanibel Gateway by IHG

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
19.1 mi from Sanctuary
8.8 out of 10, Excellent, (1,063 reviews)
"Wonderful staff, pool and on site restaurant "
United States
Lori
The price is £94
includes taxes & fees
7 May - 8 May
Doubletree by Hilton Fort Myers at Bell Tower Shops

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
14.8 mi from Sanctuary
8.8 out of 10, Excellent, (1,243 reviews)
"Staff was wonderful…guests staying were awesome !!! We will be back"
United States
Kaia
The price is £75
includes taxes & fees
14 Apr - 15 Apr
Dolphin Key Resort

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
18.3 mi from Sanctuary
8.8 out of 10, Excellent, (1,006 reviews)
"Clean room, friendly staff, convenient to everything "
United States
Tracy
The price is £92
includes taxes & fees
7 May - 8 May
Hilton Garden Inn Ft Myers

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
14.2 mi from Sanctuary
8.6 out of 10, Excellent, (1,007 reviews)
"This hotel was super clean and the staff was so friendly, I would absolutely stay here again!!"
United States
Abigail
The price is £88
includes taxes & fees
5 May - 6 May
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
14.3 mi from Sanctuary
9.2 out of 10, Wonderful, (1,014 reviews)
"Amazing property! Ernesto was an absolute gem helping has throughout our stay"
Canada
Carlton
The price is £80
includes taxes & fees
23 Apr - 24 Apr
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
13.6 mi from Sanctuary
8.6 out of 10, Excellent, (987 reviews)
"We enjoyed bike riding, the pool, and the many outdoor amenities that were available. The restaurant next door was great too! Staff was very friendly and helpful!"
United States
Cindy
The price is £84
includes taxes & fees
14 Apr - 15 Apr
Latitude 26 Waterfront Resort & Marina

TriLuxe Inn & Studios

TriLuxe Inn & Studios
2.0 star property
14.1 mi from Sanctuary
8.2 out of 10, Very good, (22 reviews)
"Great mattress, enjoyed the recliners, we prefer no doors on the closet making it fast & easy to access our wardrobe, liked the Roku TV, liked the induction stove top and drainer for washing our dishes daily as opposed to having a dishwasher. "
United States
Bobbi
The price is £87
includes taxes & fees
12 May - 13 May
TriLuxe Inn & Studios

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
12 mi from Sanctuary
8.8 out of 10, Excellent, (1,002 reviews)
"Everything was nice in room. & clean. Nice place to stay"
United States
Laura
The price is £99
includes taxes & fees
5 May - 6 May
Residence Inn by Marriott Fort Myers Sanibel

InTown Suites Extended Stay Fort Myers

InTown Suites Extended Stay Fort Myers
2.0 star property
18.6 mi from Sanctuary
4.8 out of 10, (1,000 reviews)
"The room was clean"
United States
Deirdre
The price is £56
includes taxes & fees
4 May - 5 May
InTown Suites Extended Stay Fort Myers

Lazy Cuckoo Inn

Lazy Cuckoo Inn
2.0 star property
13.8 mi from Sanctuary
8.8 out of 10, Excellent, (278 reviews)
"Great location just a couple miles from the beach, close to stores and restaurants"
United States
Kayla
The price is £90
includes taxes & fees
10 May - 11 May
Lazy Cuckoo Inn

Golf Getaway: Cape Coral Condo 1 Mi to River!

Golf Getaway: Cape Coral Condo 1 Mi to River!
3.0 star property
18.2 mi from Sanctuary
The price is £243
includes taxes & fees
25 Apr - 26 Apr
Golf Getaway: Cape Coral Condo 1 Mi to River!

Lovers Key Resort

Lovers Key Resort
3.0 star property
18.8 mi from Sanctuary
8.8 out of 10, Excellent, (1,046 reviews)
"Beautiful view and the room was great!"
United States
Seana A
The price is £215
includes taxes & fees
4 May - 5 May
Lovers Key Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanctuary

Find the best Sanctuary areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Moorings Botanical Gardens and Sanibel Sea School are some notable places to visit nearby.

Top Sanctuary Hotel Reviews

Frequently asked questions

What other neighbourhoods are similar to Sanctuary?
While Sanctuary is a unique destination, the closest experiences you'll find are in areas like The Preserve or Coastal Haven, both known for their emphasis on luxury and natural beauty.

The Preserve offers a similar secluded feel, located amongst extensive natural landscaping and waterways. It's characterised by its large, custom-built homes and a focus on outdoor living, with many properties featuring private docks and direct access to the intercoastal waters. The main thoroughfare, Cypress Drive, is lined with mature trees, giving it a very private and exclusive feel.

Couples looking for a serene escape will appreciate The Preserve. The area is superb for quiet mornings on a private patio, enjoying wildlife, or spending afternoons boating directly from your property. It's ideal for those who value privacy and a connection with nature without sacrificing high-end amenities.

Coastal Haven provides a comparable upscale experience, albeit with a slightly more coastal, beach-oriented character. This neighbourhood features elegant properties, many with ocean views or direct beach access, and is known for its immaculately kept public spaces and a relaxed, yet refined, atmosphere. The central promenade, Ocean Boulevard, offers convenient access to high-end dining and boutique shops.

For those who enjoy a blend of luxury and beachside living, Coastal Haven is an excellent choice.
When is the best time to go to Sanctuary?
The best time to go to Sanctuary is during the spring (March to May) and autumn (September to November) months.

These periods offer pleasant weather, with moderate temperatures and lower humidity, making it ideal for outdoor activities and exploring the area comfortably. You'll find fewer crowds compared to the peak summer season, which means a more relaxed experience at popular attractions and easier dining reservations.

For visitors looking to enjoy the area's natural beauty, such as the numerous parks and nature trails, spring is particularly appealing with blooming flora.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Sanctuary.
How can I save on a Sanctuary hotel booking with Expedia?
Members always get our best prices. Find our best Sanctuary hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Sanctuary hotel?
Hotel prices in Sanctuary often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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