Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio: Zoo Entry & Zoorassic Park Dinosaur Experience
£22
per adult
96% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
£29
per adult
98% of travellers recommend
San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall
£31
per adult
San Antonio: Botanical Garden Admission Ticket
£14
per adult
100% of travellers recommend
The Undead: Zombie Apocalypse Escape Room at Extreme Escape
£24
per adult
Dining at Hard Rock Cafe San Antonio
£30
per traveller
76% of travellers recommend
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is £78 per night from 16 Aug to 17 Aug
£78
16 Aug - 17 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,563 reviews)
"I stayed at the hotel on 8-7-2026 and the morning of 8-8-2026 my truck windows had been broken and several of other vehicles as well I was told I’ll receive a refund for the stay but haven’t received it"
Reviewed on 14 Aug 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is £74 per night from 22 Aug to 23 Aug
£74
22 Aug - 23 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
"The friendly staff"
Reviewed on 10 Aug 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is £79 per night from 18 Aug to 19 Aug
£79
18 Aug - 19 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,403 reviews)
"Nice Quiet place to stay clean. Very good service."
Reviewed on 13 Aug 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is £97 per night from 22 Aug to 23 Aug
£97
22 Aug - 23 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,139 reviews)
"I stayed here three times in the past 3 months and it was excellent! The bar was great the only complaint I have is that it's not opened earlier. Food was excellent and it was very clean. We also took advantage of the pool which was great! Would definitely stay there again when I travel back to San ..."
Reviewed on 13 Aug 2026
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is £112 per night from 23 Aug to 24 Aug
£112
23 Aug - 24 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (5,070 reviews)
"Fantastic rooftop pool, beautiful room, great historical building, super helpful and friendly staff, great complimentary happy hour drinks and free breakfast, and great access to Riverwalk. Drury Plaza Riverwalk hotel is our new go to stay in San Antonio. Just wish the parking was more ..."
Reviewed on 13 Aug 2026
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
The price is £77 per night from 7 Sept to 8 Sept
£77
7 Sept - 8 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a fitness centre and parking (surcharge). Our guests praise the breakfast and the ...
8/10 Very good! (4,055 reviews)
"The ac wasn’t working the had to move us rooms and still problem with ac"
Reviewed on 13 Aug 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, Alamo Quarry Market and San Antonio Zoo and Aquarium are top sights worth seeing.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
