Medical Center District Travel Guide

San Antonio

River walk in San Antonio
Riverboat on the San Antonio River Walk, San Antonio, Texas, United States of America.
River walk in San Antonio
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Popular places to visit

Things to do


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is £77 per night from 12 May to 13 May
£77
12 May - 13 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,349 reviews)
Good hotel

Reviewed on 11 May 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is £88 per night from 29 May to 30 May
£88
29 May - 30 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,062 reviews)
The hotel’s location is great. The reception staff was welcoming and friendly, and the rooms are always clean.

Reviewed on 11 May 2026

San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is £85 per night from 18 May to 19 May
£85
18 May - 19 May
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,009 reviews)
When I checked for a week and payed CASH IN TOWN FOR A MILITARY EVENT AT LACKLAND AFB DRIVE 25 hours, NO ONE INFORMED ME IF I HAD TO LEAVE EARLY I NEED TO GIVE A NOTICE OR THE HOTEL WOULD RETAIN A FEE OF 129.00. It just not a way to handle playing customers of over 25 years!

Reviewed on 8 May 2026

Courtyard by Marriott Medical Center San Antonio
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
The price is £77 per night from 12 May to 13 May
£77
12 May - 13 May
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (6,474 reviews)
The TV in the room did not work. they were not able to fix it

Reviewed on 11 May 2026

Riverwalk Plaza
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3 out of 5
105 S Saint Marys Street San Antonio TX
The price is £130 per night from 7 Jun to 8 Jun
£130
7 Jun - 8 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,624 reviews)
Wonderful in every way!

Reviewed on 11 May 2026

Drury Plaza Hotel San Antonio Riverwalk
Menger Hotel

Menger Hotel

3.5 out of 5
204 Alamo Plaza San Antonio TX
The price is £71 per night from 12 May to 13 May
£71
12 May - 13 May
includes taxes & fees
Stay at this historic hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the bar in their reviews. ...
8.8/10 Excellent! (3,996 reviews)
We were disappointed in the front desk staff and the valet staff. After our first night (at 9:00 am) we asked for fresh towels (spilled coffee) and another roll of toilet paper (only provided 1 and we were already out). They said it would be brought to us shortly. We left and came back about 2:00 ...

Reviewed on 11 May 2026

Menger Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

SanAntonio_UniversityofTexasSanAntonio_502634_03

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Shearer Hills - Ridgeview

While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and San Pedro Driving Range & Par 3 Course.

Shearer Hills - Ridgeview
River Walk in San Antonio, Texas

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or San Antonio River while you're exploring the area.

Midtown
Historic architecture Spanish San Antonio Texas Mission San Jose on a cloudy day

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
Tobin Hill

Tobin Hill

Tobin Hill might not have many top sights, but San Antonio Zoo and Aquarium and San Antonio Museum of Art are two attractions nearby that you can check out.

Tobin Hill
Dallas Skyline Reflection on Trinity River During Sunset, Dallas, Texas.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Uptown


Medical Center District Travel Guide

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