Medical Center District Travel Guide
San Antonio





Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do

San Antonio: Zoo Entry & Zoorassic Park Dinosaur Experience
£22
per adult
96% of travellers recommend

San Antonio: Discovery Tour at Natural Bridge Caverns
£29
per adult
98% of travellers recommend

San Antonio: Twisted Trails Zip Rails, Ropes & Climbing Wall
£31
per adult

San Antonio: Botanical Garden Admission Ticket
£14
per adult
100% of travellers recommend

The Undead: Zombie Apocalypse Escape Room at Extreme Escape
£24
per adult

Dining at Hard Rock Cafe San Antonio
£30
per traveller
76% of travellers recommend
Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is £78 per night from 16 Aug to 17 Aug
£78
16 Aug - 17 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...

Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is £74 per night from 21 Aug to 22 Aug
£74
21 Aug - 22 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
"The friendly staff"
Reviewed on 10 Aug 2026

Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is £79 per night from 18 Aug to 19 Aug
£79
18 Aug - 19 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,403 reviews)
"Nice Quiet place to stay clean. Very good service."
Reviewed on 13 Aug 2026

San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is £88 per night from 13 Sept to 14 Sept
£88
13 Sept - 14 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...

Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is £119 per night from 18 Aug to 19 Aug
£119
18 Aug - 19 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (5,070 reviews)
"Fantastic rooftop pool, beautiful room, great historical building, super helpful and friendly staff, great complimentary happy hour drinks and free breakfast, and great access to Riverwalk. Drury Plaza Riverwalk hotel is our new go to stay in San Antonio. Just wish the parking was more ..."
Reviewed on 13 Aug 2026

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
The price is £77 per night from 7 Sept to 8 Sept
£77
7 Sept - 8 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a fitness centre and parking (surcharge). Our guests praise the breakfast and the ...
8/10 Very good! (4,054 reviews)
"."
Reviewed on 13 Aug 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Medical Center District hotel availability
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.

Downtown San Antonio
A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.

Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, Alamo Quarry Market and San Antonio Zoo and Aquarium are top sights worth seeing.

Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.


















