Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio: Botanical Garden Admission Ticket
£13
per adult
100% of travellers recommend
San Antonio: Fredericksburg Wineries Day Trip with Tastings
£134
per adult
100% of travellers recommend
Dining at Hard Rock Cafe San Antonio
£30
per traveller
76% of travellers recommend
The Undead: Zombie Apocalypse Escape Room at Extreme Escape
£24
per adult
The Buckhorn Saloon & Museum and Texas Ranger Museum Admission
£17
per adult
84% of travellers recommend
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is £79 per night from 1 Oct to 2 Oct
£79
1 Oct - 2 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,691 reviews)
"Room was clean and was nice. Property was dated and smelled musty. Breakfast coffee was cold."
Reviewed on 29 Sept 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
Fully refundableReserve now, pay when you stay
The price is £80 per night from 19 Oct to 20 Oct
£80
19 Oct - 20 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,480 reviews)
"It was a great stay, we had breakfast and dinner on the house."
Reviewed on 30 Sept 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is £88 per night from 8 Oct to 9 Oct
£88
8 Oct - 9 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is £77 per night from 30 Oct to 31 Oct
£77
30 Oct - 31 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,170 reviews)
"It was OK. It was comfortable and clean and people were very kind. I will say that the air-conditioning unit was broken and it kept turning on full blast being very loud and rackety for 60 seconds and then completely shutting off it did that for hours and disturbed my sleep when it was maybe 4 o’clock ..."
Reviewed on 27 Sept 2026
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
The price is £151 per night from 25 Oct to 26 Oct
£151
25 Oct - 26 Oct
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (3,161 reviews)
"This place is very nice and has clean rooms. My complaint, housekeeping never cleaned our room even when we put the sign out. We were there 5 days....they only came 1 time and that's because I asked management to have someone clean our room, only for them to throw out our newly purchased dinner we ..."
Reviewed on 30 Sept 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
The price is £79 per night from 1 Oct to 2 Oct
£79
1 Oct - 2 Oct
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Medical Center District hotel availability
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Uptown Central
If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.
