Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio: Fredericksburg Wineries Day Trip with Tastings
£133
per adult
100% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
£28
per adult
98% of travellers recommend
San Antonio: Botanical Garden Admission Ticket
£13
per adult
100% of travellers recommend
The Undead: Zombie Apocalypse Escape Room at Extreme Escape
£24
per adult
The Haunted Ghost Bus Tour in San Antonio
£43
per adult
96% of travellers recommend
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is £80 per night from 5 Jul to 6 Jul
£80
5 Jul - 6 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,446 reviews)
"Provides bare neccesities. Had to pay extra $11 for parking which wasn’t disclosed. Lastly, everyday i had to go back to the front desk to get my key reprogrammed. Smh."
Reviewed on 28 Jun 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is £96 per night from 12 Jul to 13 Jul
£96
12 Jul - 13 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,091 reviews)
"I urge any future traveler to skip this hotel. I called the hotel to make sure they had a crib for newborn, which they confirmed and so I proceeded with the reservation. When we arrived, at almost midnight, the front desk guy checked us in, and then said that they didn’t have any cribs and all they ..."
Reviewed on 25 Jun 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is £81 per night from 5 Jul to 6 Jul
£81
5 Jul - 6 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,361 reviews)
"Great staff even the managers were helping clean and pick up during breakfast and dinner."
Reviewed on 27 Jun 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is £80 per night from 11 Jul to 12 Jul
£80
11 Jul - 12 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is £115 per night from 12 Jul to 13 Jul
£115
12 Jul - 13 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,810 reviews)
"The free breakfast and happy hour dinner was great"
Reviewed on 28 Jun 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
The price is £80 per night from 5 Jul to 6 Jul
£80
5 Jul - 6 Jul
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very good! (6,447 reviews)
"Staff was very friendly and helpful"
Reviewed on 28 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from San Antonio River to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Stone Creek Village and Stone Ridge Market while you're in town.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
