Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Stay near popular Medical Center District attractions
Things to do
San Antonio: Fredericksburg Wineries Day Trip with Tastings
£133
per adult
100% of travellers recommend
San Antonio: Discovery Tour at Natural Bridge Caverns
£28
per adult
98% of travellers recommend
San Antonio: Botanical Garden Admission Ticket
£13
per adult
100% of travellers recommend
The Undead: Zombie Apocalypse Escape Room at Extreme Escape
£24
per adult
The Haunted Ghost Bus Tour in San Antonio
£43
per adult
96% of travellers recommend
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is £80 per night from 5 Jul to 6 Jul
£80
5 Jul - 6 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very good! (3,451 reviews)
"Decent stay"
Reviewed on 28 Jun 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is £96 per night from 12 Jul to 13 Jul
£96
12 Jul - 13 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,093 reviews)
"Great location nice room for family"
Reviewed on 28 Jun 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is £81 per night from 5 Jul to 6 Jul
£81
5 Jul - 6 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,364 reviews)
"My stay at Drury Inn & Suites was absolutely outstanding! From the moment I checked in, the staff made me feel genuinely welcome with their warm, friendly, and professional service. Every employee I encountered went above and beyond to make sure my stay was comfortable. The hotel was spotless, from ..."
Reviewed on 28 Jun 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
The price is £80 per night from 25 Jul to 26 Jul
£80
25 Jul - 26 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is £115 per night from 9 Jul to 10 Jul
£115
9 Jul - 10 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,815 reviews)
"The stay was great. Derek was great at check in & throughout the stay when we needed assistance. The food was great. Our room was very cozy. We will return."
Reviewed on 28 Jun 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
The price is £80 per night from 5 Jul to 6 Jul
£80
5 Jul - 6 Jul
includes taxes & fees
Stay at this family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the helpful ...
8/10 Very good! (6,450 reviews)
"Staff was very friendly and helpful"
Reviewed on 28 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from San Antonio River to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Stone Ridge Market and Shops at Hardy Oak while you're in town.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
