TOP Business Hotels in Quad Cities for 2026

A historic building with a clock tower and a modern glass building with a US Bank sign.

Change your mind
Book hotels with free cancellation
Treat yourself
Save instantly and earn perks with One Key
Learn about One Key
Be picky
Search almost a million properties worldwide

Check availability on Quad Cities Business Hotels

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Quad Cities business-friendly hotels

Premium bedding, pillow-top beds, in-room safe, desk

North Executive Suite, 1 King, Non-Smoking | Premium bedding, pillow-top beds, in-room safe, desk

1. Isle Casino Hotel Bettendorf - A Caesars Rewards Destination

Bettendorf

Nicholas

£82

includes taxes & fees

27 Sept - 28 Sept

Standard Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi

2. Comfort Inn & Suites Davenport - Quad Cities

Davenport

Rada

£66

includes taxes & fees

20 Sept - 21 Sept

Suite, 1 King Bed | Living area | TV, pay films

3. DoubleTree by Hilton Davenport

Downtown Davenport

Kathy

£69

includes taxes & fees

20 Sept - 21 Sept

Standard Room, 2 Queen Beds, Balcony (Feature) | Premium bedding, down duvets, in-room safe, desk

Suite, 1 Bedroom, River View | Premium bedding, down duvets, in-room safe, desk

Premium bedding, down duvets, in-room safe, desk

4. Holiday Inn Express Le Claire Riverfront-Davenport by IHG

Le Claire

Jennifer

£91

includes taxes & fees

20 Sept - 21 Sept

Premium bedding, in-room safe, desk, iron/ironing board

5. Rhythm City Casino Resort

Davenport

JAMES

£99

includes taxes & fees

21 Sept - 22 Sept

6. Wyndham Moline on John Deere Commons

Moline

Joshua Adam

£83

includes taxes & fees

20 Sept - 21 Sept

Desk, blackout curtains, iron/ironing board, free WiFi

7. Hyatt House East Moline Quad Cities

East Moline

Thomas

£86

includes taxes & fees

4 Oct - 5 Oct

8. Hyatt Place East Moline Quad Cities

East Moline

Patricia

£83

includes taxes & fees

20 Sept - 21 Sept

View all properties

Top Quad Cities Hotel Reviews

Isle Casino Hotel Bettendorf - A Caesars Rewards Destination

10/10 Excellent

"The check in staff was friendly & excellent, along with the casino staff. The one thing we really missed was no hand or body cream, no eye makeup remover samples in bathrooms. One of us had forgotten a toothbrush. We could purchase them from check in area but at a premium cost."

Sleep Inn & Suites Davenport - Quad Cities

10/10 Excellent

"Very comfortable beds and pillows"

Frequently asked questions

How much do business hotels in Quad Cities cost?

Business hotels in Quad Cities range between £66 and £116 per night. This means you can book a property with perks like WiFi and workspaces at a price that won't break the bank. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business hotels in Quad Cities?

Quad Cities has multiple business hotels with a total average guest review rating of 8.9. One of the most popular is Hotel Blackhawk, Autograph Collection. Get the job done from this 4-star option, which includes a swimming pool and a pillowtop mattress. Another highly rated stay among corporate travellers is Holiday Inn Hotel & Suites Davenport, an IHG Hotel. It has a 3-star rating and amenities such as premium bedding and a terrace.

How many business hotels are there in Quad Cities?

Quad Cities has 36 hotels that cater to business travellers. Whether your ideal base is having a location close to the city centre or amenities such as conference rooms and workspaces, you'll find a well-suited property with Expedia.

What are the best cheap business hotels in Quad Cities?

Business hotels in Quad Cities start from £66 per night, so your next work-related trip doesn't need to stretch the finances. My Place Hotel - Davenport/Quad Cities IA is an affordable property that comes with many amenities, like front desk services and free self parking. Hampton Inn & Suites Davenport is another budget stay that's popular with corporate guests. Conveniences here include a swimming pool and free use of a nearby fitness centre. However, your Quad Cities visit shouldn't be all work and no play. Head out and discover some fun and free attractions, such as Rhythm City Casino and Isle Casino Bettendorf. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Are there any family-friendly hotels in Quad Cities that are also business friendly?

Element Moline appeals to both corporate and leisure guests. A swimming pool and a nearby beach are just two of the amenities available at this 3-star Quad Cities escape. Alternatively, book a break with the kids and make deals on the go at The Axis Moline Hotel, Tapestry Collection by Hilton. You'll have use of conveniences such as room service and laundry facilities at this comfortable 3.5-star option. Of course, there's more to do in Quad Cities apart from work! Round up the kids and explore popular family-friendly attractions, such as The TBK Bank Sports Complex and John Deere Pavilion.

Why book your business hotel in Quad Cities with Expedia?

At Expedia, it's our job to help you find an excellent stay at the right price. From 5-star corporate-friendly escapes to affordable motor inns filled with all the amenities you need, you'll have your next work trip planned in just a few clicks.

How can I find cheap business hotels in Quad Cities?

When work takes you on the road in Quad Cities, our "business friendly" filter will help you find the perfect hotel. From free WiFi to workspaces and meeting rooms, they have the amenities you need to get down to business. Another tip? Refine your search by your budget and preferred star rating to see the most affordable options.

What is there to do in Quad Cities near my business hotel?

There are loads of wonderful things to see and experience in Quad Cities. Don't miss major attractions like Adler Theatre, Circa 21 Dinner Playhouse and Putnam Museum. Figge Art Museum, German American Heritage Centre and TaxSlayer Centre also lure many visitors.

Explore a world of travel with Expedia

Historic Route 66 Holidays

Book Business Hotels in Quad Cities on Expedia.com

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Quad Cities Business Hotels

Our top choices for Quad Cities business-friendly hotels

1. Isle Casino Hotel Bettendorf - A Caesars Rewards Destination