Title: Hotels in Perryville, MO - Best Perryville Hotels from £53 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Perryville](https://expedia.co.uk/Perryville-Holiday-Rentals.d6134448.Travel-Guide-HolidayRentals)[Perryville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Perryville.d6134448.Car-Hire-Guide)[Perryville Holidays](https://expedia.co.uk/Perryville.d6134448.Holidays-City-Breaks) ![Arched train bridge](https://images.trvl-media.com/place/6134448/9dc94c46-c0ab-4d3f-b5fe-2d6ecd4d81c3.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Perryville, MO from £53 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Perryville Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Perryville%2C+Missouri%2C+United+States+of+America®ionId=6134448&latLong=37.722755%2C-89.877479&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=POOL) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Perryville%2C+Missouri%2C+United+States+of+America®ionId=6134448&latLong=37.722755%2C-89.877479&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=PETS) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Perryville%2C+Missouri%2C+United+States+of+America®ionId=6134448&latLong=37.722755%2C-89.877479&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&lodging=CABIN) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Perryville%2C+Missouri%2C+United+States+of+America®ionId=6134448&latLong=37.722755%2C-89.877479&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=HOT_TUB) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Perryville%2C+Missouri%2C+United+States+of+America®ionId=6134448&latLong=37.722755%2C-89.877479&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&travelerType=family_friendly) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Perryville%2C+Missouri%2C+United+States+of+America®ionId=6134448&latLong=37.722755%2C-89.877479&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&lodging=APARTMENT) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Perryville%2C+Missouri%2C+United+States+of+America®ionId=6134448&latLong=37.722755%2C-89.877479&adults=2&startDate=2026-01-23&d1=2026-01-23&endDate=2026-01-25&d2=2026-01-25&amenities=WATER_PARK) ## Check prices for these dates Tonight [9 Jan - 10 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6134448&startDate=2026-01-09&endDate=2026-01-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [10 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6134448&startDate=2026-01-10&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6134448&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6134448&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Perryville hotels ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/469821a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/ab22ad5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/0c87c756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Perryville by IHG [](https://www.expedia.co.uk/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) Perryville 9.2/10 Wonderful (551 reviews) "lean, updated rooms, friendly staff and great breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda £77 includes taxes & fees 22 Jan - 23 Jan [](https://www.expedia.co.uk/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/e270ba08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/badbf4c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville [](https://www.expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) Perryville 8.4/10 Very good (945 reviews) "Great beds Temperature control " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alan £56 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/0d3bba3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/26f852d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/01a032b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Perryville I-55 [](https://www.expedia.co.uk/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) Perryville 6.6/10 (124 reviews) "Nice place would recommend Mary Jane’s if you’re looking for good food " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew £64 includes taxes & fees 15 Jan - 16 Jan [](https://www.expedia.co.uk/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ![Room, 1 King Bed | Jetted bathtub](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/6caf4858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/0ac21fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/19d8e2e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Perryville [](https://www.expedia.co.uk/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) Perryville 6.8/10 (417 reviews) "Was a nice place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lesliee £53 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/ccad2677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8447c54f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) Jackson 9.0/10 Wonderful (684 reviews) "Conveniently located, clean, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Philip £68 includes taxes & fees 13 Jan - 14 Jan [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/cb237759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/b6dd70b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/4bb6ced6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/c8196a4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Murphysboro - Carbondale by IHG [](https://www.expedia.co.uk/Carbondale-Hotels-Holiday-Inn-Express-Suites-Murphysboro-Carbondale.h63308723.Hotel-Information) Murphysboro 9.4/10 Exceptional (513 reviews) "Room was clean and amenities are fantastic. My family will certainly make this our top hotel choice in the area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christian £92 includes taxes & fees 15 Jan - 16 Jan [](https://www.expedia.co.uk/Carbondale-Hotels-Holiday-Inn-Express-Suites-Murphysboro-Carbondale.h63308723.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) Jackson 9.6/10 Exceptional (1,002 reviews) "Breakfast was great- staff was welcoming. Will stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura £65 includes taxes & fees 13 Jan - 14 Jan [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/1aa84b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, Accessible, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/46ce3d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) Jackson 7.6/10 Good (428 reviews) "The staff member Tim was very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie £53 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/8a502333.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) Jackson 8.2/10 Very good (740 reviews) "Room was clean and affordable for one night. The morning person could have been more attentive to me being there for breakfast. No greeting at all and sat on her phone. I was the only one down in the breakfast area. Be more aware of her surroundings while working alone. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori £64 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Standard Room, 2 Double Beds | Blackout curtains, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/30000000/29380000/29373400/29373308/416a5c39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Blackout curtains, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/30000000/29380000/29373400/29373308/72d26ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Blackout curtains, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/30000000/29380000/29373400/29373308/3b572bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/30000000/29380000/29373400/29373308/41fbb4bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Triangle Inn Motel [](https://www.expedia.co.uk/Perryville-Hotels-Triangle-Inn-Motel.h29373308.Hotel-Information) Ste Genevieve 8.0/10 Very good (42 reviews) "The staff was very accommodating." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Herbert [](https://www.expedia.co.uk/Perryville-Hotels-Triangle-Inn-Motel.h29373308.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/a262c28f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/2880668c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![New Orleans Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/0af50b09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/35000000/34900000/34893300/34893294/354a7163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Conner House B&B [](https://www.expedia.co.uk/Chester-Hotels-The-Conner-House-Bed-And-Breakfast.h34893294.Hotel-Information) Prairie du Rocher 10/10 Exceptional (19 reviews) "Wonderful folks that work there. Nice b&b in a quiet , scenic area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bradley £117 includes taxes & fees 22 Jan - 23 Jan [](https://www.expedia.co.uk/Chester-Hotels-The-Conner-House-Bed-And-Breakfast.h34893294.Hotel-Information) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2f374258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/5aa6a52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/1ca0c293.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2e166a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (104 reviews) "It was a nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas £76 includes taxes & fees 15 Jan - 16 Jan [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted bathtub](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/19091438.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/ddade665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/333ae023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/50566fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Chester IL [](https://www.expedia.co.uk/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information) Chester 8.6/10 Excellent (352 reviews) "The room was clean and the staff were friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) RODNEY £62 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/430000/426000/425932/96e79bac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/426000/425932/46991f0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/426000/425932/7601c384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/430000/426000/425932/d63c0a0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Sainte Genevieve [](https://www.expedia.co.uk/Ste-Genevieve-Hotels-Microtel-Inn-Suites-By-Wyndham-Sainte-Genevieve.h425932.Hotel-Information) Ste Genevieve 8.8/10 Excellent (614 reviews) "Excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £62 includes taxes & fees 15 Jan - 16 Jan [](https://www.expedia.co.uk/Ste-Genevieve-Hotels-Microtel-Inn-Suites-By-Wyndham-Sainte-Genevieve.h425932.Hotel-Information) ![Classic Room, 1 King Bed | Down duvets, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/700000/692700/692668/d1c4344d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/700000/692700/692668/372ece1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, 2 Double Beds | Down duvets, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/700000/692700/692668/0a8d19e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/700000/692700/692668/d669a1ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Briarwood Inn of Sparta [](https://www.expedia.co.uk/Chester-Hotels-Briarwood-Inn-Of-Sparta.h692668.Hotel-Information) Sparta 7.6/10 Good (124 reviews) "My stay was excellent. The owner even gave me a ride to church and I am very thankful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LaQuana £54 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Chester-Hotels-Briarwood-Inn-Of-Sparta.h692668.Hotel-Information) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/331aa35f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/93f13efc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/86fc789b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/22f66a67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Sparta by IHG [](https://www.expedia.co.uk/Chester-Hotels-Holiday-Inn-Express-Hotel-Suites-Sparta.h1691121.Hotel-Information) Sparta 9.2/10 Wonderful (377 reviews) "Great place! And excellent stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Casey £83 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Chester-Hotels-Holiday-Inn-Express-Hotel-Suites-Sparta.h1691121.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11250000/11249000/11249000/bdf880f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11250000/11249000/11249000/17e335b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/12000000/11250000/11249000/11249000/282a5f73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, towels](https://images.trvl-media.com/lodging/12000000/11250000/11249000/11249000/7b2530e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sparta Motel [](https://www.expedia.co.uk/Chester-Hotels-Sparta-Motel.h11249000.Hotel-Information) Sparta 4.4/10 (67 reviews) "Nice hotel, clean, huge pool" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacey £56 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Chester-Hotels-Sparta-Motel.h11249000.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/db122c9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/5f391186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/622c9d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/bca42102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madison Inn Lodge [](https://www.expedia.co.uk/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) Fredericktown 7.6/10 Good (297 reviews) "Room was not exactly smelling nice, but room was clean and comfortable. The lodge was close to expressway and shopping. Staff was very friendly. I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve £63 includes taxes & fees 31 Jan - 1 Feb [](https://www.expedia.co.uk/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-23&endDate=2026-01-24®ionId=6134448&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPerryville-Hotels.d6134448.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPerryville-Hotels.d6134448.Travel-Guide-Hotels) ## Stay near popular Perryville attractions ### National Shrine of Our Lady of the Miraculous Medal 4.5/5 (12 reviews) Find out about the history of Perryville with a stop at National Shrine of Our Lady of the Miraculous Medal. Take in the festivals while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561876731) ### Perryville Country Club Enjoy a round of golf in Perryville at Perryville Country Club. Take in the festivals while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564822920) ### Saint Marys Lake Commune with nature and explore the great outdoors at Saint Marys Lake during your travels in Perryville. Amble around the area's parks or experience its festivals. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911400198643994624) ### Missouri's National Veterans Memorial Learn about the local history of Perryville when you spend time at Missouri's National Veterans Memorial. Amble around the area's parks or experience its festivals. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=620724250067501056) ### County Lake State Wildlife Management Area Explore the great outdoors at County Lake State Wildlife Management Area, a lovely green space in Perryville. Amble around the area's parks or experience its festivals. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911401124440145920) ### James M. Eddleman Millitary Museum You can spend an afternoon browsing the exhibits at James M. Eddleman Millitary Museum during your trip to Perryville. Amble around the area's parks or experience its festivals. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911403679970856960) ### Perryville City Hall Perryville City Hall is just one of the places to see in Perryville, so why not enjoy the other things to explore during your travels? Amble around the area's parks or experience its festivals. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911405288056512512) ### Feltz Street Park Explore the great outdoors at Feltz Street Park, a lovely green space in Perryville. Amble around the area's parks or experience its festivals. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911404486273372160) ## Perryville and related destinations - Perryville - Fergus Falls - Kewanee - Camden Historic battlefields and the charming city centre district tell stories of Missouri's Civil War past. Visit Perry County Heritage Tourism Centre and enjoy local wineries along the Mississippi Hills Wine Trail for a perfect weekend. [See all hotels in Perryville](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-23&endDate=2026-01-24&adults=2®ionId=6134448) ![Arched train bridge](https://images.trvl-media.com/place/6134448/9dc94c46-c0ab-4d3f-b5fe-2d6ecd4d81c3.jpg?impolicy=fcrop&w=899&h=599&p=1&q=high) ## Top Perryville Hotel Reviews ![Hot Tub & Creek Views: Secluded Perryville Cabin](https://images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/762b23c1_y.jpg) ### Hot Tub & Creek Views: Secluded Perryville Cabin 10/10 Excellent "Host was super helpful and the stay was top notch. What a unique old home to get to stay in!" [](https://expedia.co.uk/Perryville-Hotels-Hot-Tub-Creek-Views-Secluded-Perryville-Cabin.h115013833.Hotel-Information) ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent " It was so wonderful. I really enjoyed my time there. My children enjoyed their time there. The workers was all nice and very sweet and caring and help me with so much that I need to help with. I definitely would like to come back." [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Days Inn by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4_y.jpg) ### Days Inn by Wyndham Perryville 10/10 Excellent "No" [](https://expedia.co.uk/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "They were great " [](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Silo Farm Haus- located in the heart of wine country!](https://images.trvl-media.com/lodging/40000000/39500000/39493900/39493801/bc6052c1_y.jpg) ### Silo Farm Haus- located in the heart of wine country! 10/10 Excellent "This house was immaculate. The attention to every detail in the decor was amazing and adorable. Hosts were great. A fantastic place to stay. " [](https://expedia.co.uk/Ste-Genevieve-Hotels-Silo-Farm-Haus-Located-In-The-Heart-Of-Wine-Country.h39493801.Hotel-Information) ![New! Luxury Meets Nature - TreeRise at BaseCamp](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298154/w1258h1656x22y0-446293be_y.jpg) ### New! Luxury Meets Nature - TreeRise at BaseCamp 10/10 Excellent "We REALLY enjoyed our stay and everything was good! Very nice and clean!The fireplace didn't work flawlessly for us but that was a minor bump.Communication with the hosts was quick and responsive. Thanks to the hosts for providing such a beautiful place to unwind and reset!" [](https://expedia.co.uk/Perryville-Hotels-New-Luxury-Meets-Nature-TreeRise-At-BaseCamp.h106298154.Hotel-Information) ![Baymont by Wyndham Chester IL](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/19091438_y.jpg) ### Baymont by Wyndham Chester IL 10/10 Excellent "The hotel has been declining in recent years but the new management is working to make things better and they are doing a great job. Our room was very comfortable and clean. The staff were very friendly and helpful. It was an enjoyable experience and we will stay here again. " [](https://expedia.co.uk/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9_y.jpg) ### Super 8 by Wyndham Perryville 10/10 Excellent "The room and common area was very clean and attractive. But breakfast was a big disapp ointment. Maybe they ran out of bacon or sausage but it wasn't refilled so all of this left and 8:30 was waffles cereal and scrambled eggs." [](https://expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Beautiful location in the secluded woods ](https://images.trvl-media.com/lodging/104000000/103090000/103080200/103080140/193ecf29_y.jpg) ### Beautiful location in the secluded woods 10/10 Excellent "Great host. Secluded location. Very nice house that was spotless." [](https://expedia.co.uk/Pomona-Hotels-Beautiful-Location-In-The-Secluded-Woods.h103080140.Hotel-Information) ## More cheap stays in Perryville ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Perryville 1119 Vincent Dr Perryville MO £56 25 Jan - 26 Jan includes taxes & fees 8.4/10 Very Good! (945 reviews) [](https://expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Baymont by Wyndham Chester IL](https://images.trvl-media.com/lodging/1000000/10000/1700/1699/19091438_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Chester IL 2150 State Street Chester IL £62 11 Jan - 12 Jan includes taxes & fees 8.4/10 Very Good! (352 reviews) [](https://expedia.co.uk/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information) ![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Cape Girardeau 2520 Veterans Memorial Dr Cape Girardeau MO £76 15 Jan - 16 Jan includes taxes & fees 9.4/10 Exceptional! (104 reviews) [](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Perryville by IHG 2020 Jefferson St Perryville MO £77 22 Jan - 23 Jan includes taxes & fees 9.2/10 Wonderful! (550 reviews) [](https://expedia.co.uk/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Holiday Inn Express Hotel & Suites Sparta by IHG](https://images.trvl-media.com/lodging/2000000/1700000/1691200/1691121/331aa35f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Sparta by IHG 1301 N Market St Sparta IL £83 25 Jan - 26 Jan includes taxes & fees 9.2/10 Wonderful! (377 reviews) [](https://expedia.co.uk/Chester-Hotels-Holiday-Inn-Express-Hotel-Suites-Sparta.h1691121.Hotel-Information) ![Holiday Inn Express & Suites Murphysboro - Carbondale by IHG](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/2785ae14_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Murphysboro - Carbondale by IHG 120 MUDDY MONSTER ROAD Murphysboro IL £92 15 Jan - 16 Jan includes taxes & fees 9.4/10 Exceptional! (513 reviews) [](https://expedia.co.uk/Carbondale-Hotels-Holiday-Inn-Express-Suites-Murphysboro-Carbondale.h63308723.Hotel-Information) ## Find out more about Perryville ### Top reasons to visit Perryville - **Scenic Outdoor Adventures:** Perryville boasts stunning landscapes perfect for hiking, golfing, and exploring recreational areas. - **Cultural Attractions:** Visit shrines, museums, and memorials that showcase the town's rich heritage and history. - **Charming City Centre:** Experience the welcoming atmosphere of the city centre, full of friendly locals and quaint shops. - **Diverse Accommodation Options:** Enjoy a range of lodging, from historic hotels to pet-friendly stays, catering to all travellers. - **Romantic Getaways:** The picturesque scenery provides an ideal backdrop for couples seeking a romantic retreat. ### Find great hotels in and around Perryville Perryville, Missouri offers a delightful selection of accommodation options to suit every traveller's needs. From historic-themed hotels to pet-friendly stays, you’ll find a variety of lodging that caters to both leisure and business visitors. Whether you're seeking a comfortable suite or a unique agritourism experience, Perryville's hotels provide a charming blend of convenience and hospitality, ensuring a memorable visit to this quaint American town. - **[Super 8 by Wyndham Perryville: ](https://www.expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information)** Nestled in the heart of Perryville, Super 8 by Wyndham presents a comfortable and practical lodging option for both business and leisure travellers. This motel emphasises a business-friendly atmosphere with amenities such as a well-equipped Business Centre and Meeting Room, making it ideal for corporate needs. Its pet-friendly policy allows certain pets, ensuring that your furry companions can join you on your travels. Enjoy a hassle-free stay where essential comforts meet functionality, perfect for those seeking convenience without compromising on comfort. - **[Baymont by Wyndham Chester IL: ](https://www.expedia.co.uk/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information)** Located a mere 8.7km from Perryville, Baymont by Wyndham Chester offers a welcoming retreat for both business and leisure visitors. Known for its pet-friendly environment, this hotel provides a 24-hour Business Centre to cater to your professional requirements. Guests appreciate the relaxed atmosphere paired with essential amenities, ensuring a comfortable stay. With its convenient location and focus on service, this hotel is an excellent choice for those travelling with pets while balancing work and leisure. - **[Days Inn by Wyndham Perryville: ](https://www.expedia.co.uk/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information)** Days Inn by Wyndham Perryville is another excellent lodging option situated in Perryville, catering specifically to business travellers and pet owners. The hotel boasts a well-appointed Business Centre, ensuring that guests can efficiently manage their work tasks. With a pet-friendly policy allowing pets on-site, it guarantees a pleasant stay for all family members. The inviting atmosphere and practical amenities make Days Inn a reliable choice for travellers seeking both comfort and convenience. ### Where to stay in and around Perryville Perryville, Missouri, offers a delightful mix of outdoor adventure and romantic scenery, perfect for a memorable getaway. Explore the charming city centre, where friendly locals welcome you with open arms. Nearby attractions promise a variety of excursions, allowing you to immerse yourself in the region's vibrant atmosphere. Don't miss the chance to visit popular destinations that showcase the unique character of Perryville and its surrounding areas, making your trip truly unforgettable. - **[Longtown: ](https://www.expedia.co.uk/Longtown-Hotels.d553248634983409987.Travel-Guide-Hotels)** Nestled within the Perryville area, Longtown is a quaint village that offers a unique blend of romantic and cultural experiences. With traveller arrivals peaking in March and the summer months, it serves as a charming getaway, particularly for couples seeking an intimate escape. Visitors can explore the local historic landmarks, which provide a glimpse into the region's rich heritage. While the colder months see a slight dip in tourist numbers, Longtown's warm community spirit and entertainment-themed events ensure that there is always something to enjoy. - **[Lithium: ](https://www.expedia.co.uk/Lithium-Hotels.d553248634983113033.Travel-Guide-Hotels)** Located a mere 5.0km from Perryville, Lithium shines as a vibrant city that captures the hearts of visitors looking for entertainment and cultural immersion. The peak tourist season occurs during the summer and late autumn, making it an ideal time to visit. The city boasts an array of historic attractions that showcase its storied past, while romantic venues make it a fantastic destination for couples. With a variety of activities available year-round, including festivals and local events, Lithium promises a delightful travel experience for all. - **[Chester: ](https://www.expedia.co.uk/Chester-Hotels.d6139861.Travel-Guide-Hotels)** Situated 8.7km away from Perryville, Chester is an outdoor enthusiast's dream, offering stunning scenery and adventure at every turn. With peak visitor numbers in the summer and late autumn, Chester attracts those keen on exploring its recreational areas, golf courses, and breathtaking natural parks. The proximity to lakes and national parks makes it perfect for hiking, fishing, and enjoying the great outdoors. Whether you're seeking relaxation or adventure, Chester provides an unforgettable experience in a picturesque setting. ### Things to do in and around Perryville Perryville, Missouri, is a delightful destination for outdoor enthusiasts and couples seeking a scenic getaway. Visitors can enjoy a variety of activities, including exploring recreational areas and playing a round of golf at local courses. With its charming landscapes, Perryville provides the perfect backdrop for a romantic holiday or an adventurous outdoor excursion. **Shopping** Perryville offers quaint shops like the local gift boutiques, perfect for unique souvenirs. If you're up for a drive, visit the nearby Cape Girardeau Shopping Centre, where you’ll discover a variety of retail stores and eateries to enhance your shopping experience. **Recreation** At Perryville Country Club, enjoy a round of golf amidst lush landscapes, perfect for relaxation and sport. Nearby, Chester Skating Rink offers thrilling ice skating for adventure seekers. For a tranquil escape, explore Pickle Springs Natural Area, where nature’s serenity invites you to unwind and rejuvenate. **Adventure** In Perryville, explore the scenic trails at the nearby Trail of Tears State Park, perfect for hiking and wildlife spotting. For a thrill, visit the local escape rooms, where you can test your wits and teamwork skills in a fun, challenging environment. **Nightlife** Perryville offers a charming nightlife with venues like the lively McGowan’s Pub, perfect for enjoying local brews and live music. For a more laid-back experience, visit the Perryville Community Center, where events and gatherings create a welcoming atmosphere for all visitors. ### Booking tips and Expedia advantages for Perryville To save money during your visit to Perryville, consider travelling between November and January, when accommodation prices are at their lowest. Take advantage of free attractions like the National Shrine of Our Lady of the Miraculous Medal and explore on foot or use public transport for budget-friendly travel. Book your stay on a Wednesday for the best rates and utilise Expedia to compare hotel deals and package savings on flights and activities. Don't forget to filter for eco-certified options for sustainable stays. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Perryville are November to January, where the prices are slightly lower. This is in comparison to April to May and July, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Perryville is Wednesday. The most expensive day to stay in Perryville is Saturday. - **Find cheap hotels on Expedia:** Utilise Expedia's search tool to refine your preferences, such as budget, desired location, and the type of hotel you wish to stay in. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels currently available. To discover the best prices and offers, simply sort the price filter from lowest to highest. - **Consider bundling your trip:** You can save money by combining your hotel stay in Perryville with your flights and activities through an Expedia package deal. ### Find the best attractions in and around Perryville Perryville, Missouri, offers a delightful blend of outdoor activities and romantic scenery, making it an ideal destination for a memorable getaway. Visitors can explore a variety of attractions, including shrines, museums, and memorials that cater to those seeking cultural and family experiences. Don't miss the historic sites and popular attractions that highlight Perryville's unique charm and heritage, ensuring a fulfilling visit to this quaint American town. - **National Shrine of Our Lady of the Miraculous Medal:** Nestled in Perryville, this serene shrine is a beacon of peace and spirituality. Visitors can explore its beautiful gardens and chapels, immersing themselves in a reflective atmosphere steeped in cultural significance. - **Popeye Museum:** Located 8.1km from Perryville, this charming museum celebrates the beloved cartoon character, Popeye. Guests can enjoy an array of memorabilia and exhibits that highlight the character's cultural impact, making it a delightful stop for fans of all ages. - **Missouri's National Veterans Memorial:** Situated in Perryville, this poignant memorial honours the sacrifices of veterans. Its thoughtful design and serene surroundings provide a space for contemplation and respect, showcasing the deep cultural appreciation for those who served. ### Best time to go to Perryville The best time to visit Perryville is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 33.3°F (0.7°C) | Light Rain | Mostly Sunny | Moderately Low | Average | | February | 36.5°F (2.5°C) | Light Rain | Mostly Sunny | Moderately Low | Average | | March | 47.3°F (8.5°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | April | 56.5°F (13.6°C) | Light Rain | Mostly Sunny | Average | Average | | May | 66.4°F (19.1°C) | Light Rain | Mostly Sunny | Average | Average | | June | 75.7°F (24.3°C) | Light Rain | Mostly Sunny | Moderately High | Slightly High | | July | 78.6°F (25.9°C) | Light Rain | Mostly Sunny | Moderately High | Slightly High | | August | 76.6°F (24.8°C) | Light Rain | Mostly Sunny | Average | Slightly High | | September | 70.5°F (21.4°C) | Light Rain | Mostly Sunny | Average | Average | | October | 58.8°F (14.9°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | November | 46.4°F (8.0°C) | Light Rain | Mostly Sunny | Moderately High | Slightly Low | | December | 38.8°F (3.8°C) | Light Rain | Mostly Sunny | Moderately Low | Average | ### The nearest major airports for your trip to Perryville Accessing Perryville, Missouri, is convenient via several nearby airports. Marion, IL (MWA-Williamson County Regional) is located 29.2km away, with good hotel options such as [Drury Inn & Suites Marion](https://www.expedia.co.uk/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information), just 1.2km from the airport, and [Best Western Marion Hotel](https://www.expedia.co.uk/Carbondale-Hotels-Best-Western-Marion-Hotel.h97975.Hotel-Information), 1.9km away. Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is situated 23.6km from Perryville, hosting hotels like [Drury Plaza Hotel Cape Girardeau Conference Center](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information), 3.7km from the airport, and [Drury Inn & Suites Cape Girardeau](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information), 3.1km away. Cairo, IL (CIR-Cairo Regional) lies 36.0km from Perryville, featuring accommodations like Quality Inn Cairo I-57, merely 1.2km from the airport. ## Frequently asked questions ### What are the best hotels in Perryville that travellers recommend? ### What are the top pet-friendly hotels in Perryville? ### What are the best budget hotels in Perryville? > Another excellent option is Urban Lofts, which boasts a traveller review score of 9.2\. This hotel offers a unique stay with family-friendly amenities like a kitchen for in-room dining and pet-friendly options, making it ideal for those traveling with furry friends. Guests appreciate the comfort of Egyptian cotton sheets and the convenience of free WiFi, ensuring a relaxed and enjoyable experience. > > > For those looking for more budget options, [Super 8 by Wyndham Perryville](https://www.expedia.co.uk/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) provides an affordable stay with an indoor pool and free breakfast, rated 8.4 by travellers. This property welcomes families with its accessible parking and 24-hour fitness facilities, making it a practical choice for those seeking value. > > > If you're traveling as a couple or solo, [Days Inn by Wyndham Perryville](https://www.expedia.co.uk/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) offers a cozy atmosphere with an outdoor seasonal pool and a business centre for those needing to catch up on work. Quality Inn Perryville I-55 features an inviting outdoor pool and hot tub, superb for leisurely afternoons, making it a nice retreat for couples or travellers looking to unwind. View all [budget hotels in Perryville](https://www.expedia.co.uk/Perryville-Hotels-Budget-Hotels.0-0-d6134448-tBudgetHotels.Travel-Guide-Filter-Hotels). ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Perryville hotel booking with Expedia? ### How much is the nightly rate at a Perryville hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Allenville Hotels ](https://www.expedia.co.uk/Allenville-Hotels.d553248634983340903.Travel-Guide-Hotels) - [Arcadia Hotels ](https://www.expedia.co.uk/Arcadia-Hotels.d6346857.Travel-Guide-Hotels) - [Bismarck Hotels ](https://www.expedia.co.uk/Bismarck-Hotels.d553248634983538264.Travel-Guide-Hotels) - [Bloomsdale Hotels ](https://www.expedia.co.uk/Bloomsdale-Hotels.d3000444549.Travel-Guide-Hotels) - [Bonne Terre Hotels ](https://www.expedia.co.uk/Bonne-Terre-Hotels.d55598.Travel-Guide-Hotels) - [Adults Only Resorts & in Cape Girardeau ](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Adults-Only-Resorts.0-0-d820-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Historic Hotels in Cape Girardeau ](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Historic-Hotel.0-0-d820-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Cape Girardeau Hotels ](https://www.expedia.co.uk/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels) - [Desloge Hotels ](https://www.expedia.co.uk/Desloge-Hotels.d55671.Travel-Guide-Hotels) - [Doe Run Hotels ](https://www.expedia.co.uk/Doe-Run-Hotels.d3000349343.Travel-Guide-Hotels) - [Farmington Hotels ](https://www.expedia.co.uk/Farmington-Hotels.d6058764.Travel-Guide-Hotels) - [Flat River Hotels ](https://www.expedia.co.uk/Flat-River-Hotels.d183474.Travel-Guide-Hotels) - [Fredericktown Hotels ](https://www.expedia.co.uk/Fredericktown-Hotels.d55114.Travel-Guide-Hotels) - [French Village Hotels ](https://www.expedia.co.uk/French-Village-Hotels.d553248635975849064.Travel-Guide-Hotels) - [Friedheim Hotels ](https://www.expedia.co.uk/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels) - [Glen Allen Hotels ](https://www.expedia.co.uk/Glen-Allen-Hotels.d553248634983455025.Travel-Guide-Hotels) - [Ironton Hotels ](https://www.expedia.co.uk/Ironton-Hotels.d6053585.Travel-Guide-Hotels) - [Jackson Hotels ](https://www.expedia.co.uk/Jackson-Hotels.d55765.Travel-Guide-Hotels) - [Junction City Hotels ](https://www.expedia.co.uk/Junction-City-Hotels.d553248634983410095.Travel-Guide-Hotels) - [Leadwood Hotels ](https://www.expedia.co.uk/Leadwood-Hotels.d3000349432.Travel-Guide-Hotels) - [Marble Hill Hotels ](https://www.expedia.co.uk/Marble-Hill-Hotels.d3000445212.Travel-Guide-Hotels) - [Marquand Hotels ](https://www.expedia.co.uk/Marquand-Hotels.d553248634983260789.Travel-Guide-Hotels) - [Middle Brook Hotels ](https://www.expedia.co.uk/Middle-Brook-Hotels.d3000445241.Travel-Guide-Hotels) - [New Offenburg Hotels ](https://www.expedia.co.uk/New-Offenburg-Hotels.d3000349478.Travel-Guide-Hotels) - [Park Hills Hotels ](https://www.expedia.co.uk/Park-Hills-Hotels.d183485.Travel-Guide-Hotels) - [Sedgewickville Hotels ](https://www.expedia.co.uk/Sedgewickville-Hotels.d3000349537.Travel-Guide-Hotels) - [Resorts in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotel-Resorts.d6058763-aaHotelResorts.Travel-Guide-Accommodation) - [Golf Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Golf-Hotels.0-0-d6058763-tGolfHotels.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Hotel-With-Connecting-Rooms.0-0-d6058763-thotelwithconnectingrooms.Travel-Guide-Filter-Hotels) - [Hotels with smoking rooms in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Hotels-With-Smoking-Rooms.0-0-d6058763-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [La Quinta Inn & Suites Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-La-Quinta-Inn-Suites.0-0-d6058763--bLaQuintaInnSuites.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Luxury-Hotel.0-0-d6058763-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Pet-Friendly-Hotel.0-0-d6058763-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Romantic-Hotel.0-0-d6058763-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri-Hotels-Spa-Hotels.0-0-d6058763-tSpaHotels.Travel-Guide-Filter-Hotels) - [Southeast Missouri Hotels ](https://www.expedia.co.uk/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels) - [Hotels near Southeast Missouri State University ](https://www.expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) - [St Mary Hotels ](https://www.expedia.co.uk/St-Mary-Hotels.d3000445480.Travel-Guide-Hotels) - [Ste Genevieve Hotels ](https://www.expedia.co.uk/Ste-Genevieve-Hotels.d183502.Travel-Guide-Hotels) - [Valles Mines Hotels ](https://www.expedia.co.uk/Valles-Mines-Hotels.d3000349575.Travel-Guide-Hotels) - [Weingarten Hotels ](https://www.expedia.co.uk/Weingarten-Hotels.d553248635975847364.Travel-Guide-Hotels) - [Flights to Bonne Terre ](https://www.expedia.co.uk/Cheap-Flights-To-Bonne-Terre.d55598.Travel-Guide-Flights) - [Flights to Cape Girardeau ](https://www.expedia.co.uk/Cheap-Flights-To-Cape-Girardeau.d820.Travel-Guide-Flights) - [Flights to Desloge ](https://www.expedia.co.uk/Cheap-Flights-To-Desloge.d55671.Travel-Guide-Flights) - [Flights to Festus ](https://www.expedia.co.uk/Cheap-Flights-To-Festus.d8094.Travel-Guide-Flights) - [Flights to Park Hills ](https://www.expedia.co.uk/Cheap-Flights-To-Park-Hills.d183485.Travel-Guide-Flights) - [Flights from Cape Girardeau Municipal ](https://www.expedia.co.uk/lp/airports/cgi/flights-from-cape-girardeau-municipal-airport) - [Flights from Park Hills ](https://www.expedia.co.uk/lp/flights/183485/flights-from-park-hills) - [Flights from Ste Genevieve ](https://www.expedia.co.uk/lp/flights/183502/flights-from-ste-genevieve) - [Flights from Pilot Knob ](https://www.expedia.co.uk/lp/flights/3000008143/flights-from-pilot-knob) - [Flights from Doe Run ](https://www.expedia.co.uk/lp/flights/3000349343/flights-from-doe-run) - [Flights from Herculaneum ](https://www.expedia.co.uk/lp/flights/3000349395/flights-from-herculaneum) - [Flights from Tiff ](https://www.expedia.co.uk/lp/flights/3000349564/flights-from-tiff) - [Flights from Fredericktown ](https://www.expedia.co.uk/lp/flights/55114/flights-from-fredericktown) - [Flights from Marquand ](https://www.expedia.co.uk/lp/flights/553248634983260789/flights-from-marquand) - [Flights from Altenburg ](https://www.expedia.co.uk/lp/flights/553248634983289075/flights-from-altenburg) - [Flights from Zalma ](https://www.expedia.co.uk/lp/flights/553248634983373716/flights-from-zalma) - [Flights from Frohna ](https://www.expedia.co.uk/lp/flights/553248634983521632/flights-from-frohna) - [Flights from Scott City ](https://www.expedia.co.uk/lp/flights/553248634983544376/flights-from-scott-city) - [Flights from Bonne Terre ](https://www.expedia.co.uk/lp/flights/55598/flights-from-bonne-terre) - [Flights from Jackson ](https://www.expedia.co.uk/lp/flights/55765/flights-from-jackson) - [Flights from Farmington ](https://www.expedia.co.uk/lp/flights/6058764/flights-from-farmington) - [Flights from De Soto ](https://www.expedia.co.uk/lp/flights/6085105/flights-from-de-soto) - [Flights from Arcadia ](https://www.expedia.co.uk/lp/flights/6346857/flights-from-arcadia) - [Flights from Cape Girardeau ](https://www.expedia.co.uk/lp/flights/820/flights-from-cape-girardeau) - [Flights from Atlanta (ATL) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/atl/cgi/atlanta-to-cape-girardeau) - [Flights from Birmingham (BHM) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/bhm/cgi/birmingham-to-cape-girardeau) - [Flights from Mumbai (BOM) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/bom/cgi/mumbai-to-cape-girardeau) - [Flights from Sedalia (DMO) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/dmo/cgi/sedalia-to-cape-girardeau) - [Flights from Dublin (DUB) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/dub/cgi/dublin-to-cape-girardeau) - [Flights from New York (JFK) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/jfk/cgi/new-york-to-cape-girardeau) - [Flights from London (LHR) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/lhr/cgi/london-to-cape-girardeau) - [Flights from Lewiston (LWS) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/lws/cgi/lewiston-to-cape-girardeau) - [Flights from Chicago (MDW) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/mdw/cgi/chicago-to-cape-girardeau) - [Flights from Stow (MMN) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/mmn/cgi/stow-to-cape-girardeau) - [Flights from Pasco (PSC) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/psc/cgi/pasco-to-cape-girardeau) - [Flights from St. Louis (STL) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/stl/cgi/st-louis-to-cape-girardeau) - [Flights from Tijuana (TIJ) to Cape Girardeau (CGI) ](https://www.expedia.co.uk/lp/flights/tij/cgi/tijuana-to-cape-girardeau) - [Visit Bonne Terre ](https://www.expedia.co.uk/Bonne-Terre.dx55598) - [Cadet Holidays ](https://www.expedia.co.uk/Cadet.d3000349308.Holidays-City-Breaks) - [Visit Crystal City ](https://www.expedia.co.uk/Crystal-City.dx553248634983519265) - [Visit Farmington ](https://www.expedia.co.uk/Farmington.dx6058764) - [Festus Holidays ](https://www.expedia.co.uk/Festus.d8094.Holidays-City-Breaks) - [Visit Fredericktown ](https://www.expedia.co.uk/Fredericktown.dx55114) - [Herculaneum Holidays ](https://www.expedia.co.uk/Herculaneum.d3000349395.Holidays-City-Breaks) - [Leadwood Holidays ](https://www.expedia.co.uk/Leadwood.d3000349432.Holidays-City-Breaks) - [Visit Southeast Missouri ](https://www.expedia.co.uk/Southeast-Missouri.dx6058763) - [Ste Genevieve Holidays ](https://www.expedia.co.uk/Ste-Genevieve.d183502.Holidays-City-Breaks) - [Ski Holiday Packages Southeast Missouri ](https://www.expedia.co.uk/lp/theme-holidays/ski-holidays/6058763/Southeast-Missouri) - [Rental cars Cape Girardeau Municipal airport ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau-Municipal.d6026978.Car-Hire-Guide) - [Car hire Cape Girardeau ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Cape-Girardeau.d820.Car-Hire-Guide) - [Car hire Ste Genevieve ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Ste-Genevieve.d183502.Car-Hire-Guide) - [Car hire Tiff ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Tiff.d3000349564.Car-Hire-Guide) - [Island Car Rentals Rental Cars in Cobalt ](https://www.expedia.co.uk/Island-Car-Rentals-Car-Rentals-In-Cobalt.d553248634983153223-c1132.Car-Rental-Guide-Suppliers) - [Offer Car Hire Rental Cars in Herculaneum ](https://www.expedia.co.uk/Offer-Car-Hire-Car-Rentals-In-Herculaneum.d3000349395-c1141.Car-Rental-Guide-Suppliers) - [Redspot Rental Cars in Oran ](https://www.expedia.co.uk/Redspot-Car-Rentals-In-Oran.d3000445386-c1078.Car-Rental-Guide-Suppliers) - [United Rental Cars in Southeast Missouri ](https://www.expedia.co.uk/United-Car-Rentals-In-Southeast-Missouri.d6058763-c1088.Car-Rental-Guide-Suppliers) - [Doe Run Holiday Rentals ](https://www.expedia.co.uk/Doe-Run-Holiday-Rentals.d3000349343.Travel-Guide-HolidayRentals) - [Pilot Knob Holiday Rentals ](https://www.expedia.co.uk/Pilot-Knob-Holiday-Rentals.d3000008143.Travel-Guide-HolidayRentals) - [Things to do in Southeast Missouri ](https://www.expedia.co.uk/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities) - [Book Hotels in Perryville on Expedia.com ](https://www.expedia.com/Perryville-Hotels.d6134448.Travel-Guide-Hotels) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app