Title: Hotels in Pamplico, SC - Best Pamplico Hotels from £48 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Pamplico](https://expedia.co.uk/Pamplico-Holiday-Rentals.d3000353197.Travel-Guide-HolidayRentals)[Pamplico Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Pamplico.d3000353197.Car-Hire-Guide)[Pamplico Holidays](https://expedia.co.uk/Pamplico.d3000353197.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Pamplico, SC from £48 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Pamplico Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2025-11-20&d1=2025-11-20&endDate=2025-11-22&d2=2025-11-22&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2025-11-20&d1=2025-11-20&endDate=2025-11-22&d2=2025-11-22&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Pamplico%2C+South+Carolina%2C+United+States+of+America®ionId=3000353197&latLong=33.995995%2C-79.570061&adults=2&startDate=2025-11-20&d1=2025-11-20&endDate=2025-11-22&d2=2025-11-22&amenities=PETS) ## Check prices for these dates Tonight [6 Nov - 7 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=3000353197&startDate=2025-11-06&endDate=2025-11-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [7 Nov - 8 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=3000353197&startDate=2025-11-07&endDate=2025-11-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=3000353197&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=3000353197&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Pamplico hotels and places to stay ![Lobby](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/0da1bc1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/da02b608.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/6fee16b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/25ba1b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Executive Inn Latta 8.2/10 Very good (915) "Perfect place to stop for the night while traveling the 95" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Caroline £82 includes taxes & fees 17 Nov - 18 Nov [](https://www.expedia.co.uk/Florence-Hotels-Best-Western-Executive-Inn.h1202776.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/22eb9cd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/a2c60bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/16ca8b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 Florence 9.0/10 Wonderful (768) "The room was spotless, check-in was courteous wonderful breakfast great hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roberta £89 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Pillow-top beds, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/bf604151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/60008f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/8f02222f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at the Crossroads Lake City 9.4/10 Exceptional (800) "We stay here every year on our way to the beach. The local galleries and shops are wonderful. The bakery is top notch. And the people are gracious and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Russell £97 includes taxes & fees 12 Nov - 13 Nov [](https://www.expedia.co.uk/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/0ea8f0b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/22e67acb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/c7afe694.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area Florence 9.2/10 Wonderful (1127) "Friendly staff, clean, great location near retail, restaurants and the highway." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn £88 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/5abcf1ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/bf29fa04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/1aa3f791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/b2e2f539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Florence - Civic Center by IHG Florence 9.4/10 Exceptional (912) "Staybridge Suites was clean and excellent location. Breakfast was excellent. Would stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anne Marie £105 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/51d8f371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0b9239a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC Florence 9.0/10 Wonderful (2176) "We only stayed one night, but honestly our stay as very comfortable, and staff very nice, and welcoming. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Williams £81 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/b5687a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | 1 bedroom, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence Florence 8.8/10 Excellent (2419) "We stayed for one 1 night after a long day of drive. The rooms were clean, " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Humberto £56 includes taxes & fees 11 Nov - 12 Nov [](https://www.expedia.co.uk/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/a45dedcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/7c55894f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/9afe242f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/dad4ec3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Marriott Florence Florence 8.8/10 Excellent (448) "Everything was very nice and the staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £85 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/c105915a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/38be55ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/f63ba12c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Florence Florence 8.0/10 Very good (1708) "Stayed one night. It was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gloria £84 includes taxes & fees 21 Nov - 22 Nov [](https://www.expedia.co.uk/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d1f8ba02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/bac50e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/ffb23f98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence Near Civic Center Florence 6.8/10 (1001) "Great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sedrin £51 includes taxes & fees 10 Nov - 11 Nov [](https://www.expedia.co.uk/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/024086db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/258371f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/6676431c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center Florence 7.8/10 Good (1247) "Room was spotless, bed extremely comfortable and staff was very helpful and courteous. Would DEFINITELY stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim £73 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/7942388a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/90789704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5a5d3612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Florence I-20 Florence 9.0/10 Wonderful (528) "Always enjoy their breakfasts Clean rooms Comfy bed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacie £85 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/a86309c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cots/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/67e23cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cots/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/44d17659.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/719d7bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Florence Florence 7.8/10 Good (685) " Wry nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy £83 includes taxes & fees 20 Nov - 21 Nov [](https://www.expedia.co.uk/Florence-Hotels-Courtyard-By-Marriott-Florence.h84519.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/0724af0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/a0ec666e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/e765049f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/92c4b04d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Florence Florence 8.6/10 Excellent (228) "The hotel was nice, staff were inviting and helpful. Room could’ve been a little cleaner but nothing too bad. I would definitely stay again!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) La'dymond £87 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/83cb7582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/37f52847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/94573105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG Florence 8.6/10 Excellent (1025) "The staff was wonderful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARY C £98 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/90a03799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/b467d613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/0d9737a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/ad99b77d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Florence Florence 8.6/10 Excellent (953) "Staff was very welcoming, friendly and professional. Very nice room, comfortable and clean. Great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Krystal £79 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Desk, laptop workspace, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/a269d3f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/222a1b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/8d075bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/ada13811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Florence - Civic Center Florence 6.8/10 (1001) "Very clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £48 includes taxes & fees 10 Nov - 11 Nov [](https://www.expedia.co.uk/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/618b4a3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/a6fa48ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/72e5d4f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/2dfd6373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Mullins - Marion Marion 7.6/10 Good (367) "Staff is always helpful and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Connie £72 includes taxes & fees 22 Nov - 23 Nov [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn.h24816.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free cots/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/01dca42d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/bccde616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/5b7b6acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Florence I-95 Florence 8.4/10 Very good (1001) "Was very good!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Botirbek £81 includes taxes & fees 12 Nov - 13 Nov [](https://www.expedia.co.uk/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/d963a865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/c68ab7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/43206f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/434898b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Florence I-95 Florence 8.4/10 Very good (1000) "Good place to stay, good price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos £88 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-20&endDate=2025-11-21®ionId=3000353197&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPamplico-Hotels.d3000353197.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPamplico-Hotels.d3000353197.Travel-Guide-Hotels) ## Top Pamplico Hotel Reviews ![Tru by Hilton Florence I-95](//images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg) ### Tru by Hilton Florence I-95 10/10 Excellent "Was very good!" [](https://expedia.co.uk/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![The Inn at the Crossroads](//images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76_y.jpg) ### The Inn at the Crossroads 10/10 Excellent "This hotel is always top notch! I stay here often and they always have great service, rooms are always clean, and it is so beautiful!" [](https://expedia.co.uk/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) ![Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG](//images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31_y.jpg) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG 10/10 Excellent "The toilets are entirely too low for someone over 6’4” tall" [](https://expedia.co.uk/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![TownePlace Suites by Marriott Florence](//images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6_y.jpg) ### TownePlace Suites by Marriott Florence 10/10 Excellent "All was well " [](https://expedia.co.uk/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Hyatt Place Florence Downtown](//images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321_y.jpg) ### Hyatt Place Florence Downtown 10/10 Excellent "Everything was great. The room were clean and staff was courteous." [](https://expedia.co.uk/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Florence](//images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg) ### La Quinta Inn & Suites by Wyndham Florence 10/10 Excellent "All was very good" [](https://expedia.co.uk/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Days Inn by Wyndham Florence Near Civic Center](//images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0_y.jpg) ### Days Inn by Wyndham Florence Near Civic Center 10/10 Excellent "Friendly staff and a well lit parking. " [](https://expedia.co.uk/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Hampton Inn & Suites Florence-North-I-95](//images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e_y.jpg) ### Hampton Inn & Suites Florence-North-I-95 10/10 Excellent "Yes. 100 % satisfaction. " [](https://expedia.co.uk/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ## More cheap stays in Pamplico ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Park Inn by Radisson Florence, SC 1729 Mandeville Road, Florence, SC £81 9 Nov - 10 Nov includes taxes & fees 8.8/10 Excellent! (2,185 reviews) [](https://expedia.co.uk/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Howard Johnson by Wyndham Florence 2038 W Lucas Street, I-95 Exit 164, Florence, SC £56 11 Nov - 12 Nov includes taxes & fees 8.6/10 Excellent! (2,415 reviews) [](https://expedia.co.uk/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Comfort Inn & Suites](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites 527 Woody Jones Blvd, Florence, SC £88 9 Nov - 10 Nov includes taxes & fees 9/10 Wonderful! (1,127 reviews) [](https://expedia.co.uk/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Florence Civic Center 150 Dunbarton Dr, Florence, SC £73 5 Dec - 6 Dec includes taxes & fees 7.6/10 Good! (1,248 reviews) [](https://expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Hampton Inn & Suites Florence Center](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn & Suites Florence Center 3000 W Radio Dr, Florence, SC £82 30 Nov - 1 Dec includes taxes & fees 9/10 Wonderful! (797 reviews) [](https://expedia.co.uk/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG 2101 Florence Harllee Blvd, Florence, SC £98 16 Nov - 17 Nov includes taxes & fees 8.4/10 Very Good! (1,021 reviews) [](https://expedia.co.uk/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ## Frequently asked questions ### When is the best time to go to Pamplico? > The most popular time to visit Pamplico is in April. During this month, the weather is typically warm and pleasant, with temperatures averaging around 22 to 25 Celsius, making it an excellent time for outdoor activities and exploring the scenic surroundings. > > > > As the peak season stretches from March to June, visitors flock to Pamplico to enjoy a variety of events and attractions. This bustling period is superb for those who appreciate vibrant local culture, as you can partake in numerous festivals and community gatherings that highlight the region's rich traditions. The comfortable climate allows for leisurely walks through the charming streets, where you can discover local shops and cafes while soaking in the lively atmosphere. > > > > For families or groups seeking engaging experiences, April is particularly appealing. The longer daylight hours provide ample time for sightseeing, whether it's visiting nearby nature reserves or participating in outdoor sports. The region's lush landscapes and welcoming parks create ideal settings for picnics and relaxation. > > > > If you're looking for a more budget-friendly option, consider visiting in February. During this time, this month offers a unique opportunity to enjoy the local culture without the crowds, and you can still find enjoyable activities, such as exploring historical sites or sampling traditional cuisine at local eateries. ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Pamplico hotel for you. ### How can I save on a Pamplico hotel booking with Expedia? > Members always get our best prices. Find our best Pamplico hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings. ### How much is the nightly rate at a Pamplico hotel? > Prices for hotels in Pamplico often vary, but you can find a great deal from £48 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. 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