Beginning of main content
Nectar
Collect Nectar points

Book on the go and pay later.

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check Prices on Hotels in Florence

Tonight Tonight 23 May - 24 May
This weekend This weekend 25 May - 27 May
Next weekend Next weekend 1 Jun - 3 Jun

Top 10 Hotels in Florence

Get 200 Nectar points when you book your hotel

Simply enter your Nectar card number when prompted. Your points will be credited 30 days after you return from your trip.

La Quinta Inn & Suites Florence

La Quinta Inn & Suites Florence

2123 W Lucas St, Florence
    2.5 out of 5.0
     
     

    Situated in Florence, this hotel is within 6 miles (10 km) of Mcleod Regional Medical Center, Florence Museum and Florence Civic Center. Magnolia Mall and Darlington ...

    La Quinta Inn & Suites FlorenceGet Rates

    La Quinta Inn & Suites FlorenceGet Rates
    Red Roof Inn Florence - Civic Center

    Red Roof Inn Florence - Civic Center

    2690 David H McLeod Boulevard, Florence
      2.0 out of 5.0
       
       

      Situated near the airport, this hotel is within a 10-minute walk of Magnolia Mall and Florence Civic Center. Florence Museum and Mcleod Regional Medical Center ...

      Red Roof Inn Florence - Civic CenterGet Rates

      Red Roof Inn Florence - Civic CenterGet Rates
      Country Inn & Suites by Radisson, Florence, SC

      Country Inn & Suites by Radisson, Florence, SC

      1739 Mandeville Rd, Florence
        2.5 out of 5.0
         
         

        Situated in Florence, this hotel is within 6 miles (10 km) of Mcleod Regional Medical Center, Florence Museum and Magnolia Mall. Florence Civic Center and Darlington ...

        Country Inn & Suites by Radisson, Florence, SCGet Rates

        Country Inn & Suites by Radisson, Florence, SCGet Rates
        Best Western Inn

        Best Western Inn

        1808 W Lucas Street, Florence
          2.5 out of 5.0
           
           

          Situated in Florence, this hotel is within 6 miles (10 km) of Florence Museum, Mcleod Regional Medical Center and Florence Civic Center. Magnolia Mall and Darlington ...

          Best Western Inn£80

          Best Western Inn£80
          Baymont Inn & Suites Florence by Wyndham

          Baymont Inn & Suites Florence by Wyndham

          1826 W Lucas Street, Florence
            2.0 out of 5.0
             
             

            Situated in Florence, this hotel is within 6 miles (10 km) of Mcleod Regional Medical Center, Florence Museum and Florence Civic Center. Magnolia Mall and Darlington ...

            Baymont Inn & Suites Florence by WyndhamGet Rates

            Baymont Inn & Suites Florence by WyndhamGet Rates
            Hampton Inn Suites FlorenceNorthI95

            Hampton Inn Suites FlorenceNorthI95

            1735 Stokes Road, Florence
               
               

              Situated in Florence, this hotel is 2.8 mi (4.6 km) from Beaver Creek Golf Club and within 6 mi (10 km) of Mcleod Regional Medical Center and Florence Museum. ...

              Hampton Inn Suites FlorenceNorthI95Get Rates

              Hampton Inn Suites FlorenceNorthI95Get Rates
              Fairfield Inn & Suites by Marriott Florence I-20

              Fairfield Inn & Suites by Marriott Florence I-20

              501 Woody Jones Boulevard, Florence
                2.5 out of 5.0
                 
                 

                Situated in Florence, this hotel is within 1 mile (2 km) of Florence Civic Center and Magnolia Mall. Florence Museum and Mcleod Regional Medical Center are also ...

                Fairfield Inn & Suites by Marriott Florence I-20Get Rates

                Fairfield Inn & Suites by Marriott Florence I-20Get Rates
                Holiday Inn Ex Hotel & Suites Florence I-95 & I-20 Civic Ctr

                Holiday Inn Ex Hotel & Suites Florence I-95 & I-20 Civic Ctr

                3440 W Radio Dr, Florence
                  2.5 out of 5.0
                   
                   

                  Located in the heart of Florence, this hotel is within 1 mile (2 km) of Florence Civic Center and Magnolia Mall. The Traces Golf Club and Florence Museum are ...

                  Holiday Inn Ex Hotel & Suites Florence I-95 & I-20 Civic Ctr£95

                  Holiday Inn Ex Hotel & Suites Florence I-95 & I-20 Civic Ctr£95
                  Super 8 by Wyndham Florence

                  Super 8 by Wyndham Florence

                  1832 1/2 Lucas Street, I95 Exit 164, Florence
                    2.0 out of 5.0
                     
                     

                    Situated in Florence, this motel is within 6 miles (10 km) of Mcleod Regional Medical Center, Florence Museum and Florence Civic Center. Magnolia Mall and Darlington ...

                    Super 8 by Wyndham FlorenceGet Rates

                    Super 8 by Wyndham FlorenceGet Rates
                    Days Inn by Wyndham Florence/I-95 North

                    Days Inn by Wyndham Florence/I-95 North

                    2111 West Lucas St/I-95, Florence
                      2.0 out of 5.0
                       
                       

                      Situated in Florence, this motel is within 6 miles (10 km) of Mcleod Regional Medical Center, Florence Museum and Magnolia Mall. Florence Civic Center and Darlington ...

                      Days Inn by Wyndham Florence/I-95 NorthGet Rates

                      Days Inn by Wyndham Florence/I-95 NorthGet Rates
                      Map

                      Florence Hotel Reviews

                      Travel to Florence & Explore


                      Explore Florence with Expedia's Travel Guides to find the best flights, cars, holiday packages and more!