Find hotels in Effingham, SC from £47

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Effingham hotels

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,653 reviews)
"Great stay"
United States
Priscila
The price is £55
includes taxes & fees
24 May - 25 May
Howard Johnson by Wyndham Florence

Quality Inn Mullins - Marion

Quality Inn Mullins - Marion
2.5 star property
Marion
7.8 out of 10, Good, (398 reviews)
"It was ok clean would stay there again. "
United States
jeff
The price is £79
includes taxes & fees
21 May - 22 May
Quality Inn Mullins - Marion

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.4 out of 10, Exceptional, (582 reviews)
"Great stay"
United States
Nicole
The price is £89
includes taxes & fees
17 May - 18 May
Holiday Inn Express & Suites Latta by IHG

Best Western Executive Inn

Best Western Executive Inn
2.5 star property
Latta
8.2 out of 10, Very good, (987 reviews)
"I had a wonderful stay at the hotel, where the staff was incredibly friendly and attentive. The clean and comfortable rooms, along with the convenient location, made my experience truly enjoyable!"
United States
Taras
The price is £86
includes taxes & fees
3 May - 4 May
Best Western Executive Inn

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (899 reviews)
"Great staff. Great place to stay!"
United States
Debra
The price is £85
includes taxes & fees
10 May - 11 May
Hampton Inn & Suites Florence-North-I-95

Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence
2.0 star property
Florence
6.8 out of 10, (1,001 reviews)
"It was ok no frills had to ask for towel replacements breakfast was minimal,bed comfortable "
United States
Teresa
The price is £50
includes taxes & fees
28 Apr - 29 Apr
Microtel Inn & Suites by Wyndham Florence

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,266 reviews)
"I love this place I would stay again "
United States
Shunicee
The price is £82
includes taxes & fees
11 May - 12 May
Comfort Inn & Suites Florence Center Area

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,265 reviews)
"Great stay!"
United States
Lisa
The price is £63
includes taxes & fees
25 May - 26 May
Park Inn by Radisson Florence, SC

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,005 reviews)
"Excellent hotel so clean, friendy staff "
United States
Fanny
The price is £101
includes taxes & fees
4 May - 5 May
Hyatt Place Florence Downtown

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1,002 reviews)
"It was clean and breakfast was good "
United States
Samina
The price is £83
includes taxes & fees
3 May - 4 May
Tru by Hilton Florence I-95

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very good, (82 reviews)
"Clean rooms. Helpful staff good location. It will be better if they offer better options in breakfast."
United States
TORAL
The price is £77
includes taxes & fees
3 May - 4 May
Spark by Hilton Florence North I-95, SC

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
7.0 out of 10, Good, (1,009 reviews)
"Clean, very quiet , staff very friendly, safe place. "
United States
María
The price is £55
includes taxes & fees
28 Apr - 29 Apr
Days Inn by Wyndham Florence Near Civic Center

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1,002 reviews)
"One night stay"
United States
Dalet
The price is £101
includes taxes & fees
30 Apr - 1 May
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Super 8 by Wyndham Florence

Super 8 by Wyndham Florence
2.0 star property
Florence
7.0 out of 10, Good, (1,002 reviews)
"Clean room and great staff."
United States
Sameer
The price is £48
includes taxes & fees
4 May - 5 May
Super 8 by Wyndham Florence

Sleep Inn Florence North

Sleep Inn Florence North
2.5 star property
Florence
7.4 out of 10, Good, (715 reviews)
"Clean, friendly staff. Good breakfast (typical kind). Good overnight stop on the way back home."
Canada
Jeff and Marlene
The price is £56
includes taxes & fees
18 May - 19 May
Sleep Inn Florence North

Florence Inn and Suites

Florence Inn and Suites
2.5 star property
Florence
6.4 out of 10, (359 reviews)
"Needed a good bed to sleep in and we rested well."
United States
David
The price is £51
includes taxes & fees
28 Apr - 29 Apr
Florence Inn and Suites

Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1,003 reviews)
"The breakfast was great and the rooms were super comfortable "
United States
Jessica
The price is £82
includes taxes & fees
26 May - 27 May
Comfort Suites Florence I-95

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (985 reviews)
"Nice room and great breakfast "
United States
David
The price is £112
includes taxes & fees
10 May - 11 May
Staybridge Suites Florence - Civic Center by IHG

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.8 out of 10, Good, (1,000 reviews)
"For a roadside hotel it felt clean and pleasant. "
United States
Marianna
The price is £82
includes taxes & fees
28 Apr - 29 Apr
Best Western Inn

Clarion Inn & Suites Florence - Darlington

Clarion Inn & Suites Florence - Darlington
2.5 star property
Florence
4.4 out of 10, (322 reviews)
"This place is terrible"
United States
Gary
The price is £39
includes taxes & fees
13 May - 14 May
Clarion Inn & Suites Florence - Darlington
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Effingham Hotel Reviews

More cheap stays in Effingham

Frequently asked questions

What is the best area to stay in Effingham?
The best area to stay in Effingham is near the intersection of US-301 and US-52, as this offers the most convenient access to amenities and the main travel routes.

This area, often referred to as the Florence-Effingham commercial corridor, is characterised by a concentration of hotels, restaurants, and petrol stations just off the main highways. It's designed for convenience, especially for those travelling through or using Effingham as a base for exploring the wider region. You'll find most services clustered along these two major roads.

For solo travellers or couples on a road trip, this area is ideal. Its primary benefit is the ease of getting on and off the highways, simplifying onward journeys. There are also several dining options ranging from casual eateries to sit-down restaurants, making it easy to grab a meal after a day of driving.
When is the best time to go to Effingham?
The best time to visit Effingham, South Carolina, is during the spring (March to May) and autumn (September to November) months.

During these periods, the weather is pleasantly mild, with comfortable temperatures and lower humidity compared to the peak summer months. This makes it ideal for enjoying outdoor activities and exploring the local area without the intense heat. You'll find it's a great time for leisurely drives through the countryside or visiting nearby attractions.

For those planning to attend local events or simply enjoy the comfortable weather, these seasons offer the best conditions.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Effingham.
How can I save on a Effingham hotel booking with Expedia?
Members always get our best prices. Find our best Effingham hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Effingham hotel?
Prices for hotels in Effingham often vary, but you can find a great deal from £47 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia