Title: Hotels in Effingham, SC - Best Effingham Hotels from £41 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Effingham](https://expedia.co.uk/Effingham-Holiday-Rentals.d553248635975849973.Travel-Guide-HolidayRentals)[Effingham Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Effingham.d553248635975849973.Car-Hire-Guide)[Effingham Holidays](https://expedia.co.uk/Effingham.d553248635975849973.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Effingham Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Effingham%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975849973&latLong=34.057571%2C-79.75341&adults=2&startDate=2026-02-27&d1=2026-02-27&endDate=2026-03-01&d2=2026-03-01&amenities=POOL) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Effingham%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975849973&latLong=34.057571%2C-79.75341&adults=2&startDate=2026-02-27&d1=2026-02-27&endDate=2026-03-01&d2=2026-03-01&amenities=HOT_TUB) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Effingham%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975849973&latLong=34.057571%2C-79.75341&adults=2&startDate=2026-02-27&d1=2026-02-27&endDate=2026-03-01&d2=2026-03-01&amenities=PETS) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Effingham%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975849973&latLong=34.057571%2C-79.75341&adults=2&startDate=2026-02-27&d1=2026-02-27&endDate=2026-03-01&d2=2026-03-01&travelerType=family_friendly) ## Check prices for these dates Tonight [13 Feb - 14 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975849973&startDate=2026-02-13&endDate=2026-02-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [14 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975849973&startDate=2026-02-14&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975849973&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975849973&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Effingham hotels ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/a93e569b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/0e00b7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/e2ea309a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Florence Downtown [](https://www.expedia.co.uk/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) Florence 9.0/10 Wonderful (1,000 reviews) "Great location and well maintained property. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen £82 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/89338f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, Tempur-Pedic beds, in-room safe, desk](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/861e9f4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/042032ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/b2e2f539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Florence - Civic Center by IHG [](https://www.expedia.co.uk/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) Florence 9.4/10 Exceptional (957 reviews) "Room clean, bed good, breakfast good choices, front desk excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mona £118 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fefdad76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fad493a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/6df606aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area [](https://www.expedia.co.uk/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) Florence 9.2/10 Wonderful (1,224 reviews) "Room was very nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew £79 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/ddbd2495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/8b770330.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/825507c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/68010423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Florence [](https://www.expedia.co.uk/Florence-Hotels-Hilton-Garden-Inn-Florence.h1367205.Hotel-Information) Florence 8.6/10 Excellent (282 reviews) "The hotel is very pet friendly. Close to stores and restaurants. Clean, friendly, for is great in the restaurant in the hotel as well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle £94 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Florence-Hotels-Hilton-Garden-Inn-Florence.h1367205.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/9c0353ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/07b3e89f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/6c72c859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/fb5956cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG [](https://www.expedia.co.uk/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) Florence 9.2/10 Wonderful (1,001 reviews) "Clean rooms and nice breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adam £97 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/7e5ec8df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/05885eec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/59da7dea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at the Crossroads [](https://www.expedia.co.uk/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) Lake City 9.4/10 Exceptional (854 reviews) "We always enjoy our stay at the Inn. Food at the Bistro never disappoints and the bartender is always friendly and remembers us from past visits. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara £88 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/2dfd6373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/72e5d4f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/6986f055.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/a6fa48ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Mullins - Marion [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn.h24816.Hotel-Information) Marion 7.8/10 Good (387 reviews) "It was ok clean would stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) jeff £79 includes taxes & fees 7 Mar - 8 Mar [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn.h24816.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d1f8ba02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d2976b97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1f011cac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence Near Civic Center [](https://www.expedia.co.uk/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) Florence 6.8/10 (1,001 reviews) "Love this room dearly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andre £54 includes taxes & fees 18 Feb - 19 Feb [](https://www.expedia.co.uk/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/88f4ba4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/1e0c4eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/f287bfc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence Center [](https://www.expedia.co.uk/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) Florence 9.0/10 Wonderful (855 reviews) "Staff was very kind and conscious of our needs" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £90 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/e5aa7c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/af0558b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/9a944163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/91a83018.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Florence, Tapestry Collection by Hilton [](https://www.expedia.co.uk/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) Florence 8.8/10 Excellent (618 reviews) "Special place. Great staff with an outstanding restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John D £107 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/e08b1bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/4aae214d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/7c55894f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/de3f1188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Marriott Florence [](https://www.expedia.co.uk/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) Florence 8.8/10 Excellent (513 reviews) "Clean room, great location, easy check-in & check-out, friendly service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shaun £82 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/da6adbe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/f276d90d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/0724af0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/831257e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Florence [](https://www.expedia.co.uk/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) Florence 8.6/10 Excellent (279 reviews) "Room was new, clean and spacious and had a great blue tooth speaker for music. Bathrooms were very clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Defelicio £81 includes taxes & fees 18 Feb - 19 Feb [](https://www.expedia.co.uk/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/25cb76ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/c42cf41b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/2132b0fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/41091644.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Florence North I-95, SC [](https://www.expedia.co.uk/Florence-Hotels-Spark-By-Hilton-Florence-North-I-95.h42602.Hotel-Information) Florence 7.8/10 Good (46 reviews) "Wonderful staff and very clean room and facilities , " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) catherine £64 includes taxes & fees 24 Feb - 25 Feb [](https://www.expedia.co.uk/Florence-Hotels-Spark-By-Hilton-Florence-North-I-95.h42602.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/c68ab7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/5054dc3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/67a43c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/d963a865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Florence I-95 [](https://www.expedia.co.uk/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) Florence 8.4/10 Very good (1,002 reviews) "Great accommodations and courteous staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie £80 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0c64863b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC [](https://www.expedia.co.uk/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) Florence 9.0/10 Wonderful (2,237 reviews) "Room was clean, staff friendly, and the includes breakfast was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha £70 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2544034c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/fcf4fdd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/2a6d6c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds | Free cots/infant beds, free rollaway beds, bed sheets](https://images.trvl-media.com/lodging/59000000/58990000/58985600/58985556/949b4986.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Latta by IHG [](https://www.expedia.co.uk/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information) Latta 9.4/10 Exceptional (550 reviews) "Front desk is amazing! Rooms are clean and quiet. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly £94 includes taxes & fees 16 Mar - 17 Mar [](https://www.expedia.co.uk/Florence-Hotels-Holiday-Inn-Express-Suites-Latta.h58985556.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/8dae8685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/1c348a37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/dc8d999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/f82666ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) Florence 7.8/10 Good (1,265 reviews) "Quiet clean and many options local for food etc Good for a night or two stay Bed was comfortable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Louis £69 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/5b7b6acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/d5b1a48f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/8339db76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Florence I-95 [](https://www.expedia.co.uk/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) Florence 8.4/10 Very good (1,000 reviews) "We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marita £79 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/6ea04fee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite | Private kitchen | Coffee/tea maker](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/bca415cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/d32e89e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/b658ab38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Affordable Suites Florence [](https://www.expedia.co.uk/Florence-Hotels-Affordable-Suites-Florence.h57719723.Hotel-Information) Florence 9.2/10 Wonderful (137 reviews) "Nice clean room; friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angelo [](https://www.expedia.co.uk/Florence-Hotels-Affordable-Suites-Florence.h57719723.Hotel-Information) ![Desk, laptop workspace, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/868ff462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/8d075bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/6673044c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/ada13811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Florence - Civic Center [](https://www.expedia.co.uk/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) Florence 6.8/10 (1,001 reviews) "Room was good. No microwave tho. Staff was very courteous and helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £46 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-27&endDate=2026-02-28®ionId=553248635975849973&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_SPRING_PROMO_553248635975849973) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEffingham-Hotels.d553248635975849973.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEffingham-Hotels.d553248635975849973.Travel-Guide-Hotels) ## Top Effingham Hotel Reviews ![Hampton Inn & Suites Florence-North-I-95](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e_y.jpg) ### Hampton Inn & Suites Florence-North-I-95 10/10 Excellent "This has to be the cleanest Hampton Inn we’ve ever stayed at! We usually only book at Hampton Inns. The staff were all very friendly. The pool & hot tub very nice!" [](https://expedia.co.uk/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/17df73d5_y.jpg) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG 10/10 Excellent "Room was spotless!!" [](https://expedia.co.uk/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Room was great and clean, staff friendly and helpful. " [](https://expedia.co.uk/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![TownePlace Suites by Marriott Florence](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6_y.jpg) ### TownePlace Suites by Marriott Florence 10/10 Excellent "The cleanliness of the rooms, lobby, and the grounds. Staff was very helpful." [](https://expedia.co.uk/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Hampton Inn & Suites Florence Center](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003_y.jpg) ### Hampton Inn & Suites Florence Center 10/10 Excellent "Friendly staff and clean" [](https://expedia.co.uk/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Hilton Garden Inn Florence](https://images.trvl-media.com/lodging/2000000/1370000/1367300/1367205/8b770330_y.jpg) ### Hilton Garden Inn Florence 10/10 Excellent "Very clean and great customer service. " [](https://expedia.co.uk/Florence-Hotels-Hilton-Garden-Inn-Florence.h1367205.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg) ### La Quinta Inn & Suites by Wyndham Florence 10/10 Excellent "Great breakfast, friendly staff. " [](https://expedia.co.uk/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Microtel Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/cbd95825_y.jpg) ### Microtel Inn & Suites by Wyndham Florence 10/10 Excellent "The staff was amazing. The front receptionist went above and beyond to help us out. Definitely will stay again. " [](https://expedia.co.uk/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Residence Inn Marriott Florence](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/a45dedcb_y.jpg) ### Residence Inn Marriott Florence 10/10 Excellent "The room was large and clean. New. The breakfast was great. I've stayed at Residence Inns a few times and have always had excellent experiences." [](https://expedia.co.uk/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ## More cheap stays in Effingham ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Howard Johnson by Wyndham Florence 2038 W Lucas Street Florence SC £55 25 Feb - 26 Feb includes taxes & fees 8.6/10 Excellent! (2,565 reviews) [](https://expedia.co.uk/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Florence Civic Center 150 Dunbarton Dr Florence SC £69 15 Mar - 16 Mar includes taxes & fees 7.8/10 Good! (1,264 reviews) [](https://expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Park Inn by Radisson Florence, SC 1729 Mandeville Road Florence SC £70 22 Feb - 23 Feb includes taxes & fees 8.8/10 Excellent! (2,235 reviews) [](https://expedia.co.uk/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Best Western Inn](https://images.trvl-media.com/lodging/1000000/10000/500/455/344e3fdf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Inn 1808 W Lucas Street Florence SC £73 19 Feb - 20 Feb includes taxes & fees 7.6/10 Good! (1,006 reviews) [](https://expedia.co.uk/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites Florence Center Area 527 Woody Jones Blvd Florence SC £79 15 Feb - 16 Feb includes taxes & fees 9/10 Wonderful! (1,223 reviews) [](https://expedia.co.uk/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Hampton Inn & Suites Florence-North-I-95](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn & Suites Florence-North-I-95 1735 Stokes Road Florence SC £84 24 Feb - 25 Feb includes taxes & fees 8.8/10 Excellent! (859 reviews) [](https://expedia.co.uk/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Effingham? > This area, often referred to as the Florence-Effingham commercial corridor, is characterised by a concentration of hotels, restaurants, and petrol stations just off the main highways. It's designed for convenience, especially for those travelling through or using Effingham as a base for exploring the wider region. You'll find most services clustered along these two major roads. > > > For solo travellers or couples on a road trip, this area is ideal. Its primary benefit is the ease of getting on and off the highways, simplifying onward journeys. There are also several dining options ranging from casual eateries to sit-down restaurants, making it easy to grab a meal after a day of driving. ### When is the best time to go to Effingham? > During these periods, the weather is pleasantly mild, with comfortable temperatures and lower humidity compared to the peak summer months. This makes it ideal for enjoying outdoor activities and exploring the local area without the intense heat. You'll find it's a great time for leisurely drives through the countryside or visiting nearby attractions. > > > For those planning to attend local events or simply enjoy the comfortable weather, these seasons offer the best conditions. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Effingham hotel booking with Expedia? ### How much is the nightly rate at a Effingham hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Bishopville Hotels ](https://www.expedia.co.uk/Bishopville-Hotels.d6938.Travel-Guide-Hotels) - [Hilton Hotels in Blenheim ](https://www.expedia.co.uk/Blenheim-Hotels-Hilton-Hotels.0-0-d3000353092--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Blenheim Hotels ](https://www.expedia.co.uk/Blenheim-Hotels.d3000353092.Travel-Guide-Hotels) - [Cades Hotels ](https://www.expedia.co.uk/Cades-Hotels.d3000353095.Travel-Guide-Hotels) - [Centenary Hotels ](https://www.expedia.co.uk/Centenary-Hotels.d3000353100.Travel-Guide-Hotels) - 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