Title: Hotels in Effingham, SC - Best Effingham Hotels from £45 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Effingham](https://expedia.co.uk/Effingham-Holiday-Rentals.d553248635975849973.Travel-Guide-HolidayRentals)[Effingham Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Effingham.d553248635975849973.Car-Hire-Guide)[Effingham Holidays](https://expedia.co.uk/Effingham.d553248635975849973.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Effingham, SC from £45 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Effingham Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Effingham%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975849973&latLong=34.057571%2C-79.75341&adults=2&startDate=2025-11-26&d1=2025-11-26&endDate=2025-11-28&d2=2025-11-28&amenities=POOL) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Effingham%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975849973&latLong=34.057571%2C-79.75341&adults=2&startDate=2025-11-26&d1=2025-11-26&endDate=2025-11-28&d2=2025-11-28&amenities=HOT_TUB) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Effingham%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975849973&latLong=34.057571%2C-79.75341&adults=2&startDate=2025-11-26&d1=2025-11-26&endDate=2025-11-28&d2=2025-11-28&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Effingham%2C+South+Carolina%2C+United+States+of+America®ionId=553248635975849973&latLong=34.057571%2C-79.75341&adults=2&startDate=2025-11-26&d1=2025-11-26&endDate=2025-11-28&d2=2025-11-28&amenities=PETS) ## Check prices for these dates Tonight [12 Nov - 13 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975849973&startDate=2025-11-12&endDate=2025-11-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Nov - 14 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975849973&startDate=2025-11-13&endDate=2025-11-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975849973&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975849973&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Effingham hotels and places to stay ![Lobby](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/0da1bc1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/25ba1b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/6fee16b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1210000/1202800/1202776/da02b608.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Executive Inn Latta 8.2/10 Very good (917) "Check in pleasant. Second day no towels in room. Filthy. So bad we left and went elsewhere. Never again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles Belmont £81 includes taxes & fees 19 Nov - 20 Nov [](https://www.expedia.co.uk/Florence-Hotels-Best-Western-Executive-Inn.h1202776.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/06692e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/60008f7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/f75cb7bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9150000/9142300/9142228/8f02222f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at the Crossroads Lake City 9.4/10 Exceptional (807) "Extremely courteous staff; very clean and spacious room. Convenient to downtown shops and eateries. Definitely would stay again and recommend to friends and family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charlie £104 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Florence-Hotels-The-Inn-At-The-Crossroads.h9142228.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/22e67acb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/0ea8f0b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking | Pillow-top beds, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/83187168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area Florence 9.2/10 Wonderful (1138) "Friendly staff, clean, great location near retail, restaurants and the highway." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn £85 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/a2c60bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/22eb9cd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/59604fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 Florence 9.0/10 Wonderful (777) "The room was spotless, check-in was courteous wonderful breakfast great hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roberta £88 includes taxes & fees 19 Nov - 20 Nov [](https://www.expedia.co.uk/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/5abcf1ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/1aa3f791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/b2e2f539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/3bae1a69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Florence - Civic Center by IHG Florence 9.4/10 Exceptional (913) "Friendly staff, great breakfast, beautiful ammenities!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandi £114 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/a45dedcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/9afe242f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/cfe51644.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/dad4ec3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Marriott Florence Florence 8.8/10 Excellent (451) "Everything was very nice and the staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £81 includes taxes & fees 3 Dec - 4 Dec [](https://www.expedia.co.uk/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/51d8f371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC Florence 9.0/10 Wonderful (2188) "Friendly and efficient staff and a nice room for my overnight stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carole £80 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | 1 bedroom, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/b5687a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/ebea43b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence Florence 8.6/10 Excellent (2432) "Room clean, nice hot water in tub and friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon £55 includes taxes & fees 17 Nov - 18 Nov [](https://www.expedia.co.uk/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/38be55ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/824b9567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/f63ba12c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Florence Florence 8.0/10 Very good (1678) "Friendly staff, clean just what I was looking for!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bradford £84 includes taxes & fees 21 Nov - 22 Nov [](https://www.expedia.co.uk/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d2976b97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/bac50e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d1f8ba02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence Near Civic Center Florence 6.8/10 (1003) "Great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sedrin £55 includes taxes & fees 17 Nov - 18 Nov [](https://www.expedia.co.uk/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/024086db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/dc8d999b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/258371f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Florence Civic Center Florence 7.8/10 Good (1246) "Room was spotless, bed extremely comfortable and staff was very helpful and courteous. Would DEFINITELY stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tim £72 includes taxes & fees 11 Dec - 12 Dec [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5a5d3612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/90789704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/86912dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Florence I-20 Florence 9.0/10 Wonderful (531) "Always enjoy their breakfasts Clean rooms Comfy bed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stacie £88 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/a86309c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed | Desk, iron/ironing board, free cots/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/w4000h2663x0y0-4c6e3b9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cots/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/44d17659.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cots/infant beds, free rollaway beds](https://images.trvl-media.com/lodging/1000000/90000/84600/84519/67e23cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Florence Florence 7.8/10 Good (689) " Wry nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy £83 includes taxes & fees 20 Nov - 21 Nov [](https://www.expedia.co.uk/Florence-Hotels-Courtyard-By-Marriott-Florence.h84519.Hotel-Information) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/90a03799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/b467d613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/0d9737a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/ad99b77d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Florence Florence 8.6/10 Excellent (958) "Staff was very welcoming, friendly and professional. Very nice room, comfortable and clean. Great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Krystal £90 includes taxes & fees 27 Nov - 28 Nov [](https://www.expedia.co.uk/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/25ce2409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/23e97d90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/5cafd746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Queen Beds | Premium bedding, in-room safe, individually furnished, desk](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/b510c653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Florence, SC Florence 8.2/10 Very good (1002) "great check in lady Kendra so nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda £88 includes taxes & fees 19 Nov - 20 Nov [](https://www.expedia.co.uk/Florence-Hotels-Home2-Suites-By-Hilton-Florence.h7271220.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/618b4a3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/a6fa48ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/72e5d4f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/2dfd6373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Mullins - Marion Marion 7.6/10 Good (368) "Staff is always helpful and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Connie £66 includes taxes & fees 21 Nov - 22 Nov [](https://www.expedia.co.uk/Florence-Hotels-Quality-Inn.h24816.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/0724af0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/a0ec666e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/e765049f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76030000/76026200/76026194/da6adbe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Florence Florence 8.4/10 Very good (233) "good stay " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Joanne £86 includes taxes & fees 17 Nov - 18 Nov [](https://www.expedia.co.uk/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/2aa0d516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/8f49f2ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/1c7273f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/37047013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Florence Inn and Suites Florence 6.4/10 (323) "Clean and acceptable " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benjamin £45 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Florence-Hotels-Florence-Inn-And-Suites.h20253.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/bdf580c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/37f52847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/94573105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG Florence 8.6/10 Excellent (1002) "Room was spacious, clean and very bleachy smell. Staff was helpful. Morning staff very pleasant to deal with" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Curtis £91 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![Desk, laptop workspace, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/a269d3f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed (Smoke Free) | Room amenity](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/3d1c0a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/222a1b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/8d075bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Florence - Civic Center Florence 6.8/10 (1001) "Very clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £46 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-26&endDate=2025-11-27®ionId=553248635975849973&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEffingham-Hotels.d553248635975849973.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEffingham-Hotels.d553248635975849973.Travel-Guide-Hotels) ## Top Effingham Hotel Reviews ![TownePlace Suites by Marriott Florence](//images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6_y.jpg) ### TownePlace Suites by Marriott Florence 10/10 Excellent "We are repeat customers. We find the hotel customer friendly with friendly staff, clean rooms and a breakfast that is good & filling to start the next if our trip." [](https://expedia.co.uk/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Hampton Inn & Suites Florence-North-I-95](//images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e_y.jpg) ### Hampton Inn & Suites Florence-North-I-95 10/10 Excellent "Gladys at the reception was very friendly and very helpful!" [](https://expedia.co.uk/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Florence](//images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg) ### La Quinta Inn & Suites by Wyndham Florence 10/10 Excellent "Yes - spotless- staff excellent " [](https://expedia.co.uk/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Tru by Hilton Florence I-95](//images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg) ### Tru by Hilton Florence I-95 10/10 Excellent "Everything was FANTASTIC. Clean, spacious room, nice decor, games in the lobby and outside a big connect four board. Lots of fun available. Breakfast had something unique and INCREDIBLE. They had a vanilla yogurt machine dispensing farm fresh yogurt that tasted incredible!!!! I WILL be back!!! Oh- the bed was wonderful as well" [](https://expedia.co.uk/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG](//images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31_y.jpg) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG 10/10 Excellent "Room was clean and very comfortable I can’t wait to return this weekend but the only problem I had is the heater not working I was freezing in my room all night but I slept good though " [](https://expedia.co.uk/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![Hyatt Place Florence Downtown](//images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321_y.jpg) ### Hyatt Place Florence Downtown 10/10 Excellent "Everything was great. The room were clean and staff was courteous." [](https://expedia.co.uk/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Days Inn by Wyndham Florence Near Civic Center](//images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0_y.jpg) ### Days Inn by Wyndham Florence Near Civic Center 10/10 Excellent "Friendly staff and a well lit parking. " [](https://expedia.co.uk/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Courtyard by Marriott Florence](//images.trvl-media.com/lodging/1000000/90000/84600/84519/a86309c4_y.jpg) ### Courtyard by Marriott Florence 10/10 Excellent "This is a great hotel. The rooms are clean and up to date. The staff was friendly and helpful. And the food was good. I liked the way the room was arranged with sofa and side table with lots of room. We will stay here again ❤️ " [](https://expedia.co.uk/Florence-Hotels-Courtyard-By-Marriott-Florence.h84519.Hotel-Information) ## More cheap stays in Effingham ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Park Inn by Radisson Florence, SC 1729 Mandeville Road, Florence, SC £80 7 Dec - 8 Dec includes taxes & fees 8.8/10 Excellent! (2,183 reviews) [](https://expedia.co.uk/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Howard Johnson by Wyndham Florence 2038 W Lucas Street, I-95 Exit 164, Florence, SC £55 17 Nov - 18 Nov includes taxes & fees 8.6/10 Excellent! (2,425 reviews) [](https://expedia.co.uk/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Comfort Inn & Suites](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites 527 Woody Jones Blvd, Florence, SC £85 16 Nov - 17 Nov includes taxes & fees 9/10 Wonderful! (1,138 reviews) [](https://expedia.co.uk/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Quality Inn & Suites Florence Civic Center](https://images.trvl-media.com/lodging/1000000/20000/11600/11535/74f401dc_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Florence Civic Center 150 Dunbarton Dr, Florence, SC £72 11 Dec - 12 Dec includes taxes & fees 7.6/10 Good! (1,248 reviews) [](https://expedia.co.uk/Florence-Hotels-Quality-Inn-And-Suites-Civic.h11535.Hotel-Information) ![Hampton Inn & Suites Florence Center](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn & Suites Florence Center 3000 W Radio Dr, Florence, SC £81 30 Nov - 1 Dec includes taxes & fees 9/10 Wonderful! (799 reviews) [](https://expedia.co.uk/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG 2101 Florence Harllee Blvd, Florence, SC £91 16 Nov - 17 Nov includes taxes & fees 8.4/10 Very Good! (1,001 reviews) [](https://expedia.co.uk/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ## Frequently asked questions ### Where is the best place to stay in Effingham? > [Park Inn by Radisson Florence, SC](https://www.expedia.co.uk/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information), located 12.2 mi (19.6 km) from the heart of Effingham, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are [Howard Johnson by Wyndham Florence](https://www.expedia.co.uk/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) and [Comfort Inn & Suites Florence Center Area](https://www.expedia.co.uk/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information). See all available [top hotels](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975849973), or [vacation rentals in Effingham](https://www.expedia.co.uk/Effingham-Holiday-Rentals.d553248635975849973.Travel-Guide-HolidayRentals). ### What are some of the best holiday rentals that Effingham has to offer? > [Walking distance from one of South Carolina's top Medical centers.](https://www.expedia.co.uk/Florence-Hotels-Walking-Distance-From-One-Of-South-Carolinas-Top-Medical-Centers.h79668437.Hotel-Information): This holiday home rental outside of Effingham offers a garden, a selection of games and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all [vacation rentals in Effingham](https://www.expedia.co.uk/Effingham-Holiday-Rentals.d553248635975849973.Travel-Guide-HolidayRentals). ### If I need to cancel my hotel reservation in Effingham, will I receive a refund? > Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975849973&paymentType=FREE_CANCELLATION) to find flexible hotel deals in Effingham. ### What's it like to stay in Effingham? > Travellers to Effingham will find plenty to explore and enjoy. There are 129 hotels and other accommodation options in the surrounding area. Find out more about [Effingham](https://www.expedia.co.uk/Effingham.dx553248635975849973). ### What should I see while I'm in Effingham? > A favourite place to visit is [Lynches River State Park](https://www.expedia.co.uk/Lynches-River-State-Park-South-Carolina.d630146808421969920.Attraction). You'll also find [Florence National Cemetery](https://www.expedia.co.uk/Florence-National-Cemetery-Florence.d553248621532657341.Attraction) and [Florence Museum](https://www.expedia.co.uk/Florence-Museum-Florence.d6162137.Attraction) in the area. Take a look at what more there is to see and do in Expedia's [Effingham guide](https://www.expedia.co.uk/Effingham.dx553248635975849973). ### What's the seasonal weather in Effingham? > The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. 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