Title: The Best Hotels Closest to North Knoxville Medical Center in Powell - 2026 Updated Prices | Expedia.co.uk [Holiday Rentals in Powell](https://expedia.co.uk/Powell-Holiday-Rentals.d6249.Travel-Guide-HolidayRentals)[North Knoxville Medical Center Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-North-Knoxville-Medical-Center.d624557001838235648.Car-Hire-Guide)[North Knoxville Medical Center Holidays](https://expedia.co.uk/North-Knoxville-Medical-Center-Powell.d624557001838235648.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [21 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624557001838235648&startDate=2026-02-21&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [22 Feb - 23 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=624557001838235648&startDate=2026-02-22&endDate=2026-02-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=624557001838235648&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=624557001838235648&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for North Knoxville Medical Center hotels ![Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/2000000/1880000/1876400/1876339/79cd4ce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/2000000/1880000/1876400/1876339/a3bfd174.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/2000000/1880000/1876400/1876339/0ff0368b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/2000000/1880000/1876400/1876339/b29138c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Powell - Knoxville North [](https://www.expedia.co.uk/Knoxville-Hotels-Comfort-Inn-Powell-Knoxville-North.h1876339.Hotel-Information) 0.2 mi from North Knoxville Medical Center 8.8/10 Excellent (1,001 reviews) "Friendly staff, quiet, good breakfast. Really enjoyed our stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) antonio £77 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Comfort-Inn-Powell-Knoxville-North.h1876339.Hotel-Information) ![Free buffet breakfast on weekends ](https://images.trvl-media.com/lodging/1000000/70000/64300/64232/47414c52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Accessible (Communication, Accessible Tub) | Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/70000/64300/64232/7cf21864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/64300/64232/1e9523c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/70000/64300/64232/2eda0cf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Knoxville-North-I-75 Exit 112 by IHG [](https://www.expedia.co.uk/Knoxville-Hotels-Holiday-Inn-Express-Suites-Knoxville-North-I-75-Exit-112.h64232.Hotel-Information) 0.2 mi from North Knoxville Medical Center 8.4/10 Very good (928 reviews) "Room was very clean, staff very awesome, I love Holiday Inn express but I definitely recommend this Holiday Inn express..." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jayne £83 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Holiday-Inn-Express-Suites-Knoxville-North-I-75-Exit-112.h64232.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116400/116389/4bbdc2fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking | Premium bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/120000/116400/116389/a026a4cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/120000/116400/116389/62a74946.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/120000/116400/116389/ceb39065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Knoxville North I-75 [](https://www.expedia.co.uk/Knoxville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Knoxville-North-I-75.h116389.Hotel-Information) 0.1 mi from North Knoxville Medical Center 7.4/10 Good (1,000 reviews) "For a quick stop off the highway to spend a night, this hotel was fine for the value. Friendly staff, room was ok and clean and breakfast in the morning was fine too. All you really need for a quick night's stay." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Steven £76 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Knoxville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Knoxville-North-I-75.h116389.Hotel-Information) ![Suite, 1 Bedroom, Non Smoking | Jetted bathtub](https://images.trvl-media.com/lodging/1000000/30000/20600/20549/7ec564c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20549/7f22ccac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/20600/20549/23bc77c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20549/893c58ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Knoxville I-75 [](https://www.expedia.co.uk/Knoxville-Hotels-Baymont-By-Wyndham-Knoxville-I-75.h20549.Hotel-Information) 1.9 mi from North Knoxville Medical Center 6.8/10 (1,001 reviews) "For a one night stay it was worth it" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel £52 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Baymont-By-Wyndham-Knoxville-I-75.h20549.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/31000000/30350000/30345500/30345409/2849f715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/31000000/30350000/30345500/30345409/bce117ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/31000000/30350000/30345500/30345409/5cacd37d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/31000000/30350000/30345500/30345409/bb1ac38d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Knoxville North [](https://www.expedia.co.uk/Knoxville-Hotels-Days-Inn-By-Wyndham-Knoxville-North.h30345409.Hotel-Information) 1.8 mi from North Knoxville Medical Center 7.0/10 Good (604 reviews) "Room was okay, there was a yellow spot on the mattress. Overall, I think It’s good for one night stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Georgina £49 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Days-Inn-By-Wyndham-Knoxville-North.h30345409.Hotel-Information) ![Blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/12800/12755/9de65485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/12800/12755/c9416ed8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/12800/12755/db097f9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/12800/12755/45146ae7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Knoxville North/Powell [](https://www.expedia.co.uk/Knoxville-Hotels-Super-8-By-Wyndham-Knoxville-NorthPowell.h12755.Hotel-Information) 0.4 mi from North Knoxville Medical Center 6.4/10 (723 reviews) "The room was terrible. Smelled like smoke. Multiple areas of unrepaired drywall from water damage " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joe £54 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Super-8-By-Wyndham-Knoxville-NorthPowell.h12755.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/37000000/36060000/36050500/36050488/2f479a88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/37000000/36060000/36050500/36050488/99812f75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36060000/36050500/36050488/c240c253.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible (Roll-In Shower, Mobiity & Hearing) | Hypo-allergenic bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/37000000/36060000/36050500/36050488/db6f2004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Knoxville North I75 [](https://www.expedia.co.uk/Knoxville-Hotels-Tru-By-Hilton-Knoxville-North-I75.h36050488.Hotel-Information) 3 mi from North Knoxville Medical Center 9.4/10 Exceptional (1,007 reviews) "Great hotel, friendly staff and a great breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa £86 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Tru-By-Hilton-Knoxville-North-I75.h36050488.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2230000/2221400/2221381/8a506e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2230000/2221400/2221381/4c94cc06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two queen beds non smoking | In-room safe, iron/ironing board, free cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/3000000/2230000/2221400/2221381/ee2cd241.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/3000000/2230000/2221400/2221381/c4e03473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites-Knoxville/North I-75 [](https://www.expedia.co.uk/Knoxville-Hotels-Hampton-Inn-Suites-Knoxville-North-I-75.h2221381.Hotel-Information) 3.1 mi from North Knoxville Medical Center 9.4/10 Exceptional (1,000 reviews) "Friendly staff, clean rooms, nice breakfast, comfortable bed." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lucy £94 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Hampton-Inn-Suites-Knoxville-North-I-75.h2221381.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/70000000/69280000/69271800/69271710/6021e869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/70000000/69280000/69271800/69271710/5dd03e28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/70000000/69280000/69271800/69271710/df32137f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free full breakfast ](https://images.trvl-media.com/lodging/70000000/69280000/69271800/69271710/e3d7c4d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Knoxville Northwest [](https://www.expedia.co.uk/Knoxville-Hotels-Fairfield-Inn-Suites-By-Marriott-Knoxville-Northwest.h69271710.Hotel-Information) 3.2 mi from North Knoxville Medical Center 9.4/10 Exceptional (467 reviews) "Room was spotless! Staff was very pleasant, and the breakfast was delicious! Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christy £94 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Fairfield-Inn-Suites-By-Marriott-Knoxville-Northwest.h69271710.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/40000/34300/34253/w3836h2556x4y4-01a58e11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/40000/34300/34253/66fb4217.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/40000/34300/34253/w3840h2556x0y4-fcbfd574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/40000/34300/34253/w3840h2556x0y4-e6cc10f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Knoxville North I-75 [](https://www.expedia.co.uk/Knoxville-Hotels-Spark-By-Hilton-Knoxville-North-I-75.h34253.Hotel-Information) 3.2 mi from North Knoxville Medical Center 8.8/10 Excellent (163 reviews) "Great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Connie £64 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Spark-By-Hilton-Knoxville-North-I-75.h34253.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1770000/1760200/1760110/0c53c3d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1770000/1760200/1760110/d67c16ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Living area | 32-inch LED TV with digital channels, TV](https://images.trvl-media.com/lodging/2000000/1770000/1760200/1760110/daf55acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking | Living area | 32-inch LED TV with digital channels, TV](https://images.trvl-media.com/lodging/2000000/1770000/1760200/1760110/5768c9c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Knoxville North [](https://www.expedia.co.uk/Knoxville-Hotels-Comfort-Suites-North.h1760110.Hotel-Information) 3.1 mi from North Knoxville Medical Center 9.0/10 Wonderful (1,002 reviews) "We had a great stay, exactly as listed and had everything we needed. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lori £78 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Comfort-Suites-North.h1760110.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/18000000/17970000/17968500/17968407/8b0be458.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/18000000/17970000/17968500/17968407/a1861225.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/18000000/17970000/17968500/17968407/a39d46f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/18000000/17970000/17968500/17968407/dd66fd49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Knoxville N - Merchant Drive by IHG [](https://www.expedia.co.uk/Knoxville-Hotels-Holiday-Inn-Knoxville-N-Merchant-Drive.h17968407.Hotel-Information) 3.1 mi from North Knoxville Medical Center 8.8/10 Excellent (1,000 reviews) "Good staff, good room, good breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darby £80 includes taxes & fees 24 Feb - 25 Feb [](https://www.expedia.co.uk/Knoxville-Hotels-Holiday-Inn-Knoxville-N-Merchant-Drive.h17968407.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/30000/26300/26234/c12de79c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/26300/26234/1433660e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/26300/26234/9f22bb5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26300/26234/3bfa9dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Knoxville North - Merchants Drive [](https://www.expedia.co.uk/Knoxville-Hotels-Red-Roof-Inn-Knoxville-North-Merchants-Drive.h26234.Hotel-Information) 3.2 mi from North Knoxville Medical Center 6.6/10 (1,002 reviews) "Only minutes from downtown and UT. Also convenient to all major thoroughfares in and around Knoxville. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason D £53 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Knoxville-Hotels-Red-Roof-Inn-Knoxville-North-Merchants-Drive.h26234.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19900/19874/348e168b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/20000/19900/19874/a0233eca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/19900/19874/b0ad573c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/19900/19874/9423c11e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Knoxville Suites - Downtown [](https://www.expedia.co.uk/Knoxville-Hotels-Best-Western-Knoxville-Suites-Downtown.h19874.Hotel-Information) 3.2 mi from North Knoxville Medical Center 7.8/10 Good (1,004 reviews) "Clean hotel and room, great place to stay if you are in town for a Vols Game. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jess £74 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Knoxville-Hotels-Best-Western-Knoxville-Suites-Downtown.h19874.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12700/12643/e59e8d01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/20000/12700/12643/8d9b0bc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/1000000/20000/12700/12643/5555f3bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/12700/12643/ff2ec19b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Suites – Knoxville, TN [](https://www.expedia.co.uk/Knoxville-Hotels-Studio-6-Suites-Knoxville.h12643.Hotel-Information) 3.1 mi from North Knoxville Medical Center 6.4/10 (580 reviews) "Pet friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jas £57 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/Knoxville-Hotels-Studio-6-Suites-Knoxville.h12643.Hotel-Information) ![Desk, blackout curtains, free cots/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/60000/51300/51257/9e1de0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/51300/51257/0552073c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/60000/51300/51257/5d24faef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/51300/51257/1abcbc86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Knoxville Downtown Area [](https://www.expedia.co.uk/Knoxville-Hotels-Super-8-By-Wyndham-Knoxville-Downtown-Area.h51257.Hotel-Information) 3.3 mi from North Knoxville Medical Center 6.2/10 (1,005 reviews) "The clerk was very friendly. The room was clean & comfortable. I would highly recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vikki £45 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Super-8-By-Wyndham-Knoxville-Downtown-Area.h51257.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/20000/11600/11560/094f1f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11560/0f1199a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11600/11560/053324cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/11600/11560/ff402ec0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Knoxville East [](https://www.expedia.co.uk/Knoxville-Hotels-Days-Inn-By-Wyndham-Knoxville-East.h11560.Hotel-Information) 9.1 mi from North Knoxville Medical Center 6.8/10 (1,145 reviews) "They have some roaches but it really was better then some other stuff i have seen at that price. Quiet" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kendra £48 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Days-Inn-By-Wyndham-Knoxville-East.h11560.Hotel-Information) ![Hypo-allergenic bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/3000000/2240000/2239900/2239860/6565ee67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/3000000/2240000/2239900/2239860/49efa7ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2240000/2239900/2239860/d63c6943.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2240000/2239900/2239860/f85fc150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites Knoxville North I-75 [](https://www.expedia.co.uk/Knoxville-Hotels-Mainstay-Suites.h2239860.Hotel-Information) 3.3 mi from North Knoxville Medical Center 7.6/10 Good (758 reviews) "Very nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dorothy £62 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Mainstay-Suites.h2239860.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/20900/20829/d33982a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/20900/20829/50d11138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/20900/20829/a7f4fdf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/20900/20829/cd9a4989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Knoxville N - Merchant Drive [](https://www.expedia.co.uk/Knoxville-Hotels-Holiday-Inn-Knoxville-N-Merchant-Drive.h20829.Hotel-Information) 3.1 mi from North Knoxville Medical Center 7.6/10 Good (569 reviews) "Overnight on the way to destination. Slept well. All the three of us needed or wanted." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/Knoxville-Hotels-Holiday-Inn-Knoxville-N-Merchant-Drive.h20829.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/470000/461200/461196/930b891a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/470000/461200/461196/c2e124f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Jetted bathtub](https://images.trvl-media.com/lodging/1000000/470000/461200/461196/74ef0d5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/470000/461200/461196/bf7b704a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Clinton [](https://www.expedia.co.uk/Knoxville-Hotels-Baymont-By-Wyndham-Clinton.h461196.Hotel-Information) 9 mi from North Knoxville Medical Center 6.8/10 (1,002 reviews) "Rooms were decently clean and the staff was courteous. The pool area was decent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Glynton £54 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Knoxville-Hotels-Baymont-By-Wyndham-Clinton.h461196.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-08&endDate=2026-03-09®ionId=624557001838235648&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to North Knoxville Medical Center | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Suite, 1 King Bed with Sofa bed, Non Smoking \| Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/2000000/1880000/1876400/1876339/79cd4ce6.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Comfort Inn Powell - Knoxville North | 2.5 star property | 8.8Excellent1,001 reviews | View | | | | | | | ![Free buffet breakfast on weekends ](https://images.trvl-media.com/lodging/1000000/70000/64300/64232/47414c52.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Holiday Inn Express & Suites Knoxville-North-I-75 Exit 112 by IHG | 2.5 star property | 8.4Very good928 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/116400/116389/4bbdc2fc.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)La Quinta Inn & Suites by Wyndham Knoxville North I-75 | 3.0 star property | 7.4Good1,000 reviews | View | | | | | | | ![Suite, 1 Bedroom, Non Smoking \| Jetted bathtub](https://images.trvl-media.com/lodging/1000000/30000/20600/20549/7ec564c2.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Baymont by Wyndham Knoxville I-75 | 2.5 star property | 6.81,001 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/31000000/30350000/30345500/30345409/2849f715.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Days Inn by Wyndham Knoxville North | 2.5 star property | 7.0Good604 reviews | View | | | | | | ## Top North Knoxville Medical Center Hotel Reviews ![Tru by Hilton Knoxville North I75](https://images.trvl-media.com/lodging/37000000/36060000/36050500/36050488/2f479a88_y.jpg) ### Tru by Hilton Knoxville North I75 10/10 Excellent "The roo. Was very nice !! The staff was excellent. Especially Sue at checkin. She was the best!! Everyone was very nice!!" [](https://expedia.co.uk/Knoxville-Hotels-Tru-By-Hilton-Knoxville-North-I75.h36050488.Hotel-Information) ![Comfort Suites Knoxville North](https://images.trvl-media.com/lodging/2000000/1770000/1760200/1760110/dbb7cd5e_y.jpg) ### Comfort Suites Knoxville North 10/10 Excellent "Simple, clean." [](https://expedia.co.uk/Knoxville-Hotels-Comfort-Suites-North.h1760110.Hotel-Information) ![Baymont by Wyndham Knoxville I-75](https://images.trvl-media.com/lodging/1000000/30000/20600/20549/1dea93c8_y.jpg) ### Baymont by Wyndham Knoxville I-75 10/10 Excellent "Nice" [](https://expedia.co.uk/Knoxville-Hotels-Baymont-By-Wyndham-Knoxville-I-75.h20549.Hotel-Information) ![Comfort Inn Powell - Knoxville North](https://images.trvl-media.com/lodging/2000000/1880000/1876400/1876339/01741993_y.jpg) ### Comfort Inn Powell - Knoxville North 10/10 Excellent "The staff the clean rooms and the breakfast" [](https://expedia.co.uk/Knoxville-Hotels-Comfort-Inn-Powell-Knoxville-North.h1876339.Hotel-Information) ![Holiday Inn Knoxville N - Merchant Drive by IHG](https://images.trvl-media.com/lodging/18000000/17970000/17968500/17968407/c0da6867_y.jpg) ### Holiday Inn Knoxville N - Merchant Drive by IHG 10/10 Excellent "Yes, it was spotless " [](https://expedia.co.uk/Knoxville-Hotels-Holiday-Inn-Knoxville-N-Merchant-Drive.h17968407.Hotel-Information) ![Cozy 1-BR Guesthouse Knoxville - Pet Friendly/Hot Tub//Private Patio/Quiet](https://images.trvl-media.com/lodging/116000000/115500000/115493400/115493364/6b4afa4c_y.jpg) ### Cozy 1-BR Guesthouse Knoxville - Pet Friendly/Hot Tub//Private Patio/Quiet 10/10 Excellent "Host was very responsive and welcoming. The home was super cute and clean. I would definitely recommend this place and most certainly would stay there again! " [](https://expedia.co.uk/Knoxville-Hotels-Modern-1-BR-Guesthouse-Knoxville-Hot-TubPet-FriendlyPrivate-PatioQuiet.h115493364.Hotel-Information) ![Spark by Hilton Knoxville North I-75](https://images.trvl-media.com/lodging/1000000/40000/34300/34253/f519910b_y.jpg) ### Spark by Hilton Knoxville North I-75 10/10 Excellent "The rooms were very clean and spotless. The staff was very nice and very helpful when asked questions breakfast was just OK." [](https://expedia.co.uk/Knoxville-Hotels-Spark-By-Hilton-Knoxville-North-I-75.h34253.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Knoxville North I-75](https://images.trvl-media.com/lodging/1000000/120000/116400/116389/12388827_y.jpg) ### La Quinta Inn & Suites by Wyndham Knoxville North I-75 10/10 Excellent "Great rooms" [](https://expedia.co.uk/Knoxville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Knoxville-North-I-75.h116389.Hotel-Information) ![Days Inn by Wyndham Knoxville North](https://images.trvl-media.com/lodging/31000000/30350000/30345500/30345409/cb8cf498_y.jpg) ### Days Inn by Wyndham Knoxville North 10/10 Excellent "The staff was amazing extremely helpful and nice. Room was clean and just overall great stay " [](https://expedia.co.uk/Knoxville-Hotels-Days-Inn-By-Wyndham-Knoxville-North.h30345409.Hotel-Information) ## Hotels near other North Knoxville Medical Center attractions ### Knoxville Zoo 4.3/5 (333 reviews) Why not see the exotic and native animals who call Knoxville Zoo home during your holiday in Knoxville? Attend a sporting event or simply enjoy the lively bars while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621571049640) ### Max Air Trampoline Park You can take time to visit Max Air Trampoline Park during your travels to Powell. Attend a sporting event or simply enjoy the lively bars while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621571049656) ### Knoxville Expo Center 4.4/5 (20 reviews) Learn about the events happening in Knoxville Expo Center during your trip to Knoxville. Attend a sporting event or simply enjoy the lively bars while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6230527) ### Knoxville Children's Theatre You can enjoy a show at Knoxville Children's Theatre during your trip to Knoxville. Attend a sporting event or simply enjoy the lively bars while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561867320) ### Central United Methodist Church Central United Methodist Church is just one of the places to see in Knoxville, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the lively bars while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561867241) ### A1 Lab Arts You can spend an afternoon exploring the galleries in A1 Lab Arts during your travels in Knoxville. Attend a sporting event or simply enjoy the lively bars while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621569948790) ### Knoxville Center You can do some window-shopping at Knoxville Center during your stay in Knoxville. Attend a sporting event or simply enjoy the lively bars while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621569948780) ### Historic Southern Railway Station You can learn about the history of Knoxville with a trip to Historic Southern Railway Station. Attend a sporting event or simply enjoy the lively bars while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621569948791) ## Frequently asked questions ### What's the area like around North Knoxville Medical Center? ### What's the best place to stay near North Knoxville Medical Center? ### How many hotels are there close to North Knoxville Medical Center? ### If I need to cancel the hotel reservation for my stay near North Knoxville Medical Center, will I receive a refund?