A concrete structure with a sign reading "Melvin Price Locks and Dam" and a clear blue sky.

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Check prices for these dates

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

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Our top choices for National Great Rivers Museum hotels

A modern lobby with patterned armchairs, a fireplace, and a large TV on the wall.

1. Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
10.8 mi from National Great Rivers Museum
9.2 out of 10, Wonderful, (930 reviews)
"Love the coffee machine grinds beans fresh!"
United States
Kelly
The price is £105
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express & Suites Edwardsville by IHG
A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

2. Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
10.8 mi from National Great Rivers Museum
8.4 out of 10, Very good, (978 reviews)
"Very clean, nice breakfast and friendly staff"
United States
Christina
The price is £70
includes taxes & fees
29 Nov - 30 Nov
Comfort Inn Edwardsville - St. Louis
Breakfast area

3. Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton
2.5 star property
3.4 mi from National Great Rivers Museum
9.0 out of 10, Wonderful, (720 reviews)
"Welcome Kimberley on the TV when we walked in the room made us smile! The food was delicious! The staff were all so friendly and professional! We had a great stay!"
United States
kimberley
The price is £104
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn & Suites St. Louis/Alton
A modern living room with a stone fireplace, a reception desk, and a large window.

4. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
3.0 star property
9.3 mi from National Great Rivers Museum
9.2 out of 10, Wonderful, (536 reviews)
"Nice stay. Enjoyed my room."
United States
Sabra
The price is £115
includes taxes & fees
22 Nov - 23 Nov
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
An outdoor patio with a circular fire pit, seating, and a grill area.

5. TownePlace Suites by Marriott St. Louis Edwardsville, IL

TownePlace Suites by Marriott St. Louis Edwardsville, IL
3.5 star property
10.9 mi from National Great Rivers Museum
9.0 out of 10, Wonderful, (214 reviews)
"Clean room, decent breakfast, excellent location!"
United States
Jamie
The price is £131
includes taxes & fees
29 Nov - 30 Nov
TownePlace Suites by Marriott St. Louis Edwardsville, IL
A cozy lounge area with leather seating, a wooden coffee table, and a fireplace.

6. Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach
3.0 star property
9.6 mi from National Great Rivers Museum
8.4 out of 10, Very good, (918 reviews)
"The everything was so clean and nice we will stay again"
United States
venissa
The price is £86
includes taxes & fees
8 Nov - 9 Nov
Best Western Plus Pontoon Beach
A brick building with a wooden gazebo in front.

7. Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
10.9 mi from National Great Rivers Museum
8.6 out of 10, Excellent, (763 reviews)
"We loved our stay here. It is a family owned hotel and it feels very homey. We will stay here every time we travel to Edwardsville."
United States
Kristy
The price is £111
includes taxes & fees
3 Nov - 4 Nov
Country Hearth Inn & Suites Edwardsville St. Louis
A modern bathroom with a red bathtub, a white sink, and a shower. There is a bed with a white mattress and a grey curtain in the adjacent room.

8. Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
8.9 mi from National Great Rivers Museum
7.8 out of 10, Good, (745 reviews)
"Great place to stay recommend"
United States
Darrien
The price is £59
includes taxes & fees
3 Nov - 4 Nov
Red Lion Inn & Suites Pontoon Beach
A modern lobby with a stone wall, seating area, and a fireplace.

9. The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel
3.0 star property
2.4 mi from National Great Rivers Museum
7.8 out of 10, Good, (818 reviews)
"It was quiet and comfortable."
United States
Jo Ann
The price is £74
includes taxes & fees
29 Nov - 30 Nov
The Great Rivers, an Ascend Collection Hotel
A multi-story hotel with balconies, a parking lot with marked spaces, and a clear sky.

10. Bel Air Motel

Bel Air Motel
3.5 star property
2.5 mi from National Great Rivers Museum
8.6 out of 10, Excellent, (246 reviews)
"Nice stay very convenient"
United States
Sherry
The price is £70
includes taxes & fees
3 Nov - 4 Nov
Bel Air Motel
A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and a landscaped area with trees.

11. Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG
2.5 star property
3.2 mi from National Great Rivers Museum
9.0 out of 10, Wonderful, (248 reviews)
"Staff was very friendly and helpful."
United States
Emily
The price is £105
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express and Suites Alton St Louis Area by IHG
A bathroom with a white sink, a red-framed mirror, and a toilet.

12. Hampton Inn & Suites St. Louis-Edwardsville

Hampton Inn & Suites St. Louis-Edwardsville
2.5 star property
11.4 mi from National Great Rivers Museum
7.8 out of 10, Good, (114 reviews)
"Nice property enjoyed the complementary breakfast and the swimming pool"
United States
Tashae
The price is £80
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites St. Louis-Edwardsville
A reception area with a Comfort Inn sign, a reception desk, a framed picture on the wall, and a welcome mat.

13. Comfort Inn Alton near I-255

Comfort Inn Alton near I-255
2.5 star property
2.4 mi from National Great Rivers Museum
7.4 out of 10, Good, (637 reviews)
"Awesome hotel with great breakfast choices in a great location. Very clean and comfortable."
United States
Audrey
The price is £70
includes taxes & fees
4 Nov - 5 Nov
Comfort Inn Alton near I-255
A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

14. Quality Inn Florissant - St Louis

Quality Inn Florissant - St Louis
2.5 star property
12 mi from National Great Rivers Museum
7.4 out of 10, Good, (999 reviews)
"Good location, friendly staff"
Canada
Annalyn
The price is £54
includes taxes & fees
22 Nov - 23 Nov
Quality Inn Florissant - St Louis
A lobby with a blue sofa, patterned cushions, a reception desk, and a mural of a moon and arch.

15. La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
3.0 star property
9.7 mi from National Great Rivers Museum
7.6 out of 10, Good, (561 reviews)
"Very clean and nice. Price was very affordable and convenient for us. We were there for ball tournaments but it was also my wife’s birthday. We were 15 minutes from the field and 10 minutes from a very nice place I took her for her birthday"
United States
Walter
The price is £85
includes taxes & fees
15 Nov - 16 Nov
La Quinta Inn & Suites by Wyndham Pontoon Beach
A hotel entrance with a covered driveway and a parking area.

16. Best Western Plus Parkway Hotel

Best Western Plus Parkway Hotel
2.5 star property
3.3 mi from National Great Rivers Museum
8.2 out of 10, Very good, (1,001 reviews)
"Great place to stay"
United States
Missy
The price is £95
includes taxes & fees
15 Nov - 16 Nov
Best Western Plus Parkway Hotel
A compact room with a wooden desk, a black chair, a round wooden table, a black sofa, a flat-screen TV mounted on the wall, and a microwave on a black cabinet.

17. Budget Motel Granite City/St Louis Area

Budget Motel Granite City/St Louis Area
2.0 star property
7.7 mi from National Great Rivers Museum
7.0 out of 10, Good, (27 reviews)
"It's relatively decent & clean roo"
United States
Austin
The price is £51
includes taxes & fees
3 Nov - 4 Nov
Budget Motel Granite City/St Louis Area
A hotel room with a large bathtub, a small table with two chairs, a minibar, and a large mirror.

18. Econo Lodge Inn & Suites Granite City - St. Louis

Econo Lodge Inn & Suites Granite City - St. Louis
2.0 star property
7.7 mi from National Great Rivers Museum
6.4 out of 10, (288 reviews)
"THis place was OK but not great. I found another place in the area that was fantastic and at a cheaper price."
United States
Brian
The price is £51
includes taxes & fees
29 Nov - 30 Nov
Econo Lodge Inn & Suites Granite City - St. Louis
Lobby

19. Days Inn by Wyndham Pontoon Beach

Days Inn by Wyndham Pontoon Beach
2.0 star property
9.5 mi from National Great Rivers Museum
6.2 out of 10, (606 reviews)
"Property is old and tired but is kept clean and maintained as best as possible. Staff were friendly and helpful. Good value for the price, location not the best."
United Kingdom
Kelly
The price is £56
includes taxes & fees
4 Nov - 5 Nov
Days Inn by Wyndham Pontoon Beach
A hotel with a sign for AmeriViu Inn & Suites, a parking lot, and a well-lit building facade.

20. amerivu inn & suites alton

amerivu inn & suites alton
2.0 star property
3.4 mi from National Great Rivers Museum
8.0 out of 10, Very good, (1 review)
"The manager was very helpful. I thought that he couldn’t find my second room reservation, but it turned out that when Expedia asked me for the person name for the second room, they actually put that person‘s name on the reservation, even though I was making the reservation and paying for both rooms. So a note – if you’re reserving more than 1 room for traveling companions or family members, put your name on all of the rooms."
United States
Katherine
The price is £62
includes taxes & fees
3 Nov - 4 Nov
amerivu inn & suites alton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to National Great Rivers Museum

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern lobby with patterned armchairs, a fireplace, and a large TV on the wall.
Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
9.2
Wonderful
930 reviews
View
A hotel lobby with blue seating, a flat-screen TV, and a fireplace.
Comfort Inn Edwardsville - St. Louis
2.5 star property
8.4
Very good
978 reviews
View
Breakfast area
Hampton Inn & Suites St. Louis/Alton
2.5 star property
9.0
Wonderful
720 reviews
View
A modern living room with a stone fireplace, a reception desk, and a large window.
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
3.0 star property
9.2
Wonderful
536 reviews
View
An outdoor patio with a circular fire pit, seating, and a grill area.
TownePlace Suites by Marriott St. Louis Edwardsville, IL
3.5 star property
9.0
Wonderful
214 reviews
View

Top National Great Rivers Museum Hotel Reviews

21C Museum Hotel St Louis

21C Museum Hotel St Louis

10/10 Excellent
"My boyfriend & I stayed here for our anniversary since we usually spend them at home, and this was the best hotel for a staycation! From the hotel, to even restaurant staff, everyone was so pleasant. We had a Luxury King Suite and it was absolutely beautiful. We decided this hotel will become a place we start to return to for future anniversaries and I couldn’t be more excited! While we went out for Halloween and only stayed for 1 night, we never got to actually take a moment to enjoy some the of the main hotel amenities but still had the best time and we have already recommended it to others!"
Mckenna 1-night trip
Posted 6 hours ago
21C Museum Hotel St Louis

Other attractions near National Great Rivers Museum

Lincoln Douglas Square

8.4/10 (12 reviews)
Stand in the presence of U.S. history, on the spot where Lincoln and Douglas debated as statesmen two years prior to a presidential race that changed everything.
See properties

Frequently asked questions

What's the area like around National Great Rivers Museum?
National Great Rivers Museum is located in an area of Alton that travellers like for its university setting. You'll find 21 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay close to National Great Rivers Museum?
Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an indoor pool. You'll find it 14.3 mi (23 km) from National Great Rivers Museum. Other good choices around the area include Pear Tree Inn St. Louis Airport and Super 8 by Wyndham St. Louis North.
How many hotels will I be able to find close to National Great Rivers Museum?
Expedia has 21 hotels and other accommodation options a few miles from National Great Rivers Museum.
If I need to cancel the hotel reservation for my stay near National Great Rivers Museum, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the top deals on offer near National Great Rivers Museum.
What can I see and do near National Great Rivers Museum?
You'll want to browse the exhibits at Alton Prison and Historic Museum of Torture Devices. You can enjoy nature at Ellis Island, Jones-Confluence Point State Park or Columbia Bottom Conservation Area. Looking for a little shopping break? A trip to Fast Eddie's Bon Air, Mineral Springs Mall and Alton Square Mall might be just the ticket while you're in the area around National Great Rivers Museum.