Title: TOP Mesopotamia Spa Hotels for 2026 - Spas in Mesopotamia | Expedia.co.uk [Mesopotamia Travel Guide](https://expedia.co.uk/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.co.uk/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Holiday Rentals in Mesopotamia](https://expedia.co.uk/Mesopotamia-Holiday-Rentals.d6208836.Travel-Guide-HolidayRentals)[Flights to Mesopotamia](https://expedia.co.uk/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesopotamia.d6208836.Car-Hire-Guide)[Mesopotamia Holidays](https://expedia.co.uk/Mesopotamia.d6208836.Holidays-City-Breaks) ![Iguazu Falls showing a cascade](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mesopotamia Spa Hotels Tonight [16 Jan - 17 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-01-16&endDate=2026-01-17&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [17 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-01-17&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-01-16&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-01-23&endDate=2026-01-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mesopotamia hotels with a spa ![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/60e3bf31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/7876fff6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/7eec541e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Club Valle Termal Resort [](https://www.expedia.co.uk/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) Federacion 9.2/10 Wonderful (94 reviews) "Lamentablemente el lugar no refleja lo contratado por la plataforma. Cuando llegamos no tenían nuestras reservas, nos enviaron a una habitación con puerta de vidrio que no cerraba, arañas en la habitación, las sábanas viejas y manchadas, colchones vencidos y sin forro. Una experiencia espeluznante. " ![Costa Rica](https://a.travel-assets.com/egds/marks/flags/cr.svg) Pablo £93 1 Feb - 2 Feb [](https://www.expedia.co.uk/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/0e5b5ce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/384ea822.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/9f96608b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/112000000/111550000/111541700/111541690/8d2994c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mayim Hotel Termal & SPA [](https://www.expedia.co.uk/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information) Concordia 9.0/10 Wonderful (6 reviews) "Muy lindo hotel , lástima q se rompió el aire acondicionado y no hay secador de pelo an la habitación " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catalina £81 21 Jan - 22 Jan [](https://www.expedia.co.uk/Concordia-Hotels-Mayim-Hotel-Termal-SPA.h111541690.Hotel-Information) ![Couples treatment room(s), body treatments, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/96c06c0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/908e21a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/f4e90853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/77b70130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Maran Suites & Towers - Hotel & Spa [](https://www.expedia.co.uk/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information) Parana 9.2/10 Wonderful (31 reviews) "Great location and friendly, accommodating staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £71 31 Jan - 1 Feb [](https://www.expedia.co.uk/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/e9f90dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/8b439c14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/5a5e2fdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/16000000/15470000/15462600/15462513/29357765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rio Arriba Suites Apartments y Resto [](https://www.expedia.co.uk/Bella-Vista-Hotels-Rio-Arriba-Suites-Apartments-Y-Resto.h15462513.Hotel-Information) Bella Vista 8.6/10 Excellent (4 reviews) "Pessoal da recepção excelente acolhimento. Hotel bonito, falta manutenção em certos lugares. Quarto ótimo, cama com colchão selado e barulho nos ares condicionados. Café da manhã deixa a desejar. Restaurante muito bonito. " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Anonymous traveller [](https://www.expedia.co.uk/Bella-Vista-Hotels-Rio-Arriba-Suites-Apartments-Y-Resto.h15462513.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cb01ff56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/cdd97d7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/a2d4eb00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/115000000/114110000/114109800/114109755/c1286a77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Intersur Colon [](https://www.expedia.co.uk/Colon-Hotels-Intersur-Colon.h114109755.Hotel-Information) Colón 9.0/10 Wonderful (4 reviews) "Hotel antigo mas conservado. Piscina externa aquecida muito boa. Quartos confortáveis com cama, lençóis e toalhas de boa qualidade. O banheiro é pequeno, mas tem o necessário. Café da manhã com vários pães, mas sem frutas ou frios. " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Adriana £65 25 Jan - 26 Jan [](https://www.expedia.co.uk/Colon-Hotels-Intersur-Colon.h114109755.Hotel-Information) ![Executive Apartment | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/6427ef82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City Apartment | Living area | 40-inch LED TV with cable channels, Netflix, streaming services](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/f34322b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/26003866.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Duplex | Premium bedding, pillow-top beds, individually decorated](https://images.trvl-media.com/lodging/100000000/99270000/99269400/99269311/960ad1f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Agustín 1 Apart [](https://www.expedia.co.uk/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information) Parana 9.0/10 Wonderful (4 reviews) "Meu problema foi só a garagem, o apartamento é ótimo, limpeza estava impecável." ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Jose rodrigo kallas £40 19 Jan - 20 Jan [](https://www.expedia.co.uk/Parana-Hotels-Agustin-1-Apart.h99269311.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/ee9ad702.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/fc0680d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/e90b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/dd41bc20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel y Spa Termas del Este [](https://www.expedia.co.uk/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information) Federacion 8.4/10 Very good (12 reviews) "good for a 1 night stay" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Chase [](https://www.expedia.co.uk/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information) ![Sauna, steam room](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/1c9ec1fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, steam room](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/8965968d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/a0b30be4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/121000000/120520000/120517600/120517502/w1021h683x3y0-b40ed89a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Turismo Hotel Casino [](https://www.expedia.co.uk/Corrientes-Hotels-Turismo-Hotel-Casino.h120517502.Hotel-Information) Corrientes 4.0/10 (1 review) "Quarto com carpete sujo! Parede com sinal de umidade e descascando. Até a salada que pedi a noite no jantar estava passada com tomate murcho. Decepção " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Tatiana £73 25 Jan - 26 Jan [](https://www.expedia.co.uk/Corrientes-Hotels-Turismo-Hotel-Casino.h120517502.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/4ee385b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/62c5f089.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/2c7dcd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/f5d9effc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Silos Hotel [](https://www.expedia.co.uk/Santa-Fe-Parana-Hotels-Los-Silos-Hotel.h49086569.Hotel-Information) Santa Fe 9.2/10 Wonderful (29 reviews) "Unique, interesting, and very nice. Staff was outstanding. We will be back soon" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Russell £82 18 Jan - 19 Jan [](https://www.expedia.co.uk/Santa-Fe-Parana-Hotels-Los-Silos-Hotel.h49086569.Hotel-Information) ![Massages](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/bd533bb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/892799c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Massages](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/35a3b74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/97000000/96450000/96446000/96445971/ab1ba3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson Plaza La Ribera [](https://www.expedia.co.uk/Resistencia-Hotels-Howard-Johnson-Plaza-La-Ribera.h96445971.Hotel-Information) Resistencia 9.2/10 Wonderful (129 reviews) "Great location. Just across the street from a shopping mall. I had my bike on the truck bed and a safe parking was provided. The staff was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andre [](https://www.expedia.co.uk/Resistencia-Hotels-Howard-Johnson-Plaza-La-Ribera.h96445971.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-30&endDate=2026-01-31®ionId=6208836&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Mesopotamia Hotel Reviews ![Holiday Inn Express Rosario by IHG](https://images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/502819d5_y.jpg) ### Holiday Inn Express Rosario by IHG 10/10 Excellent "Clean room. Very nice staffing. Very good breakfast " [](https://expedia.co.uk/Rosario-Hotels-Holiday-Inn-Express-Rosario.h3242923.Hotel-Information) ![Holiday Inn Rosario by IHG](https://images.trvl-media.com/lodging/1000000/580000/570400/570357/61653463_y.jpg) ### Holiday Inn Rosario by IHG 10/10 Excellent "This was a great find, the staff was beyond excellent, very helpful and kind. Many spoke English which helped with my large family, most did not speak Spanish. The area is very walkable to tourist areas, bars, and restaurants. Overall excellent experience and will be going back. Amenities were excellent too, pool bar/restaurant gave us true vacation feel. " [](https://expedia.co.uk/Rosario-Hotels-Holiday-Inn-Rosario.h570357.Hotel-Information) ![Amérian Hotel Casino Gala](https://images.trvl-media.com/lodging/2000000/1200000/1197100/1197026/a75881f1_y.jpg) ### Amérian Hotel Casino Gala 10/10 Excellent "Maravilhoso! " [](https://expedia.co.uk/Resistencia-Hotels-Amerian-Hotel-Casino-Gala.h1197026.Hotel-Information) ![Hathor Concordia](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d_y.jpg) ### Hathor Concordia 10/10 Excellent "The hotel staff is very polite Service: "Friendly and efficient," "helpful," "attentive," "welcoming smile," "professional"." [](https://expedia.co.uk/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) ![Club Valle Termal Resort](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710_y.jpg) ### Club Valle Termal Resort 10/10 Excellent "La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto." [](https://expedia.co.uk/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) ![Costarenas Hotel & Spa](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362145/43c3ae01_y.jpg) ### Costarenas Hotel & Spa 2/10 Terrible "Short Version See pictures for detailed information) - Rooms and bathrooms are small, shower already tight spaced with doors that don’t close properly. - By day 3, construction noise and chemicals smells from remodeling work became a big issue. - Receptionist did not offer solutions and lied about remodeling hours. Felt uncomfortable when asked for manager’s name, and refused to give any other information. - Same receptionist reached out later to apologize and acknowledged we should have not been placed in those rooms to begin with. Offered to move us to “upgraded” rooms. - “Upgraded” rooms were even worse. One of the rooms was directly under the ones being remodeled and worked on. Noise began at 8 AM - The other two rooms did not have a functioning air conditioner. Staff gave poor excuse and just said to open windows. There’s tons of noise far into the night from motor bikes and people playing music right across the hotel. - Hotel breakfast was motel level at best. You get eggs swimming in water and some cut up ham. Toasters barely worked, and when staff was asked for replacement they appeared completely clueless. - The spa experience was good when it came to the massage. However “quiet” policy is not enforced and hearing toilets go off right next to the spa area don’t help with the experience. - Check out was the final straw. Desk staff was rude and dismissive of concerns, stating that the room “upgrade” was sufficient compensation for the troubles. " [](https://expedia.co.uk/Colon-Hotels-Costarenas-Hotel-Spa.h15362145.Hotel-Information) ![Wyndham Garden Campana](https://images.trvl-media.com/lodging/1000000/990000/983700/983698/1521535a_y.jpg) ### Wyndham Garden Campana 6/10 Okay "Televisor con problemas de funcionamiento. Ducha que baña todo el baño en lugar de ti. Ventana expuesta al paso de todo el público. " [](https://expedia.co.uk/Pilar-Hotels-Australis-Campana.h983698.Hotel-Information) ## Explore a world of travel with Expedia - More ways to book - [Book Spa Hotels in Mesopotamia on Expedia.com.ar ](https://www.expedia.com.ar/Mesopotamia-Hoteles-Hotel-Con-Spa.0-0-d6208836-tHotelconspa.Guia-filtrada-de-Hoteles)