Title: TOP Luxury Hotels in Mesopotamia for 2026 - Mesopotamia Upscale Hotels | Expedia.co.uk

[Mesopotamia Travel Guide](https://expedia.co.uk/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.co.uk/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Holiday Rentals in Mesopotamia](https://expedia.co.uk/Mesopotamia-Holiday-Rentals.d6208836.Travel-Guide-HolidayRentals)[Flights to Mesopotamia](https://expedia.co.uk/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesopotamia.d6208836.Car-Hire-Guide)[Mesopotamia Holidays](https://expedia.co.uk/Mesopotamia.d6208836.Holidays-City-Breaks)

![Iguazu Falls showing a cascade](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check availability on Mesopotamia Luxury Hotels

Tonight

[3 Mar - 4 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-03-03&endDate=2026-03-04&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Tomorrow

[4 Mar - 5 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-03-04&endDate=2026-03-05&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

This weekend

[6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-03-06&endDate=2026-03-08&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

Next weekend

[13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-03-13&endDate=2026-03-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property)

## Our top choices for Mesopotamia luxury hotels

![Suite, Terrace | Hypo-allergenic bedding, free minibar, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/3fe012c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/d9f65657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, lunch served](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/fa3aedbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, Terrace | Hypo-allergenic bedding, free minibar, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/1000000/60000/53300/53288/56e76a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

[](https://www.expedia.co.uk/Foz-Do-Iguacu-Hotels-Hotel-Das-Cataratas.h53288.Hotel-Information)

Foz do Iguaçu

9.8/10

Exceptional

(1,003 reviews)

"The hotel is in an amazing location, right near the falls and gives you access to the park out of hours to enjoy sunset over the falls or just to explore without the crowds."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Matthew

£719

includes taxes & fees

24 Mar - 25 Mar

[](https://www.expedia.co.uk/Foz-Do-Iguacu-Hotels-Hotel-Das-Cataratas.h53288.Hotel-Information)

![Indoor pool, 3 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/afaaa032.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 restaurants, breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/7f654841.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment room(s), sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/3de28959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor spa tub](https://images.trvl-media.com/lodging/1000000/980000/979400/979370/83cafc92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Iguazu Grand Resort Spa & Casino

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Iguazu-Grand-Resort-Spa-Casino.h979370.Hotel-Information)

Puerto Iguazú

9.0/10

Wonderful

(623 reviews)

"Big rooms Friendly and respectful staff Loved our stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amin

£243

1 Apr - 2 Apr

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Iguazu-Grand-Resort-Spa-Casino.h979370.Hotel-Information)

![Private pool](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/c43a985d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/596c9ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/1551ab16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/6d489a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Gran Melia Iguazú

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Gran-Melia-Iguazu.h454059.Hotel-Information)

Puerto Iguazú

9.2/10

Wonderful

(1,002 reviews)

"Great hotel, great service, great location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Adriana

£598

14 Mar - 15 Mar

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Gran-Melia-Iguazu.h454059.Hotel-Information)

![2 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/71380e56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment room(s), sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/5c71d910.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa | Balcony](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/bc8a5aa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa | Bathroom | Separate bathtub and shower, rainfall showerhead, designer toiletries](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/d0267182.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Loi Suites Iguazú Hotel

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Loi-Suites-Iguazu-Hotel.h2450070.Hotel-Information)

Puerto Iguazú

9.2/10

Wonderful

(1,003 reviews)

"The room and bathroom are super nice, the pools and the hotel are spectacular. Very attentive employees"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Miguel

£248

13 Mar - 14 Mar

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Loi-Suites-Iguazu-Hotel.h2450070.Hotel-Information)

![Minibar, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/82a469cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room (Earth) | View from room](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/7d6ce6f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Villa | Bathroom | Free toiletries, hair dryer, bidet, towels](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/3ac32bd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio Suite | Minibar, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/4000000/3030000/3021000/3020960/cf5dfc79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Reserva Virgin Lodge

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-La-Cantera-Lodge-De-Selva-By-DON.h3020960.Hotel-Information)

Puerto Iguazú

8.6/10

Excellent

(816 reviews)

"Room was spacious and clean. Front desk staff and dining room staff very friendly and welcoming "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Tara

£102

12 Mar - 13 Mar

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-La-Cantera-Lodge-De-Selva-By-DON.h3020960.Hotel-Information)

![Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/260f31f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/7644a18e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/be2eb205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/a8f544ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Saint George

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Hotel-Saint-George.h3281425.Hotel-Information)

Puerto Iguazú

8.8/10

Excellent

(1,005 reviews)

"Great location and the pool was just what you need after a long day at the falls"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Visser

£96

17 Mar - 18 Mar

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Hotel-Saint-George.h3281425.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/1cddc3b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/f8a901a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/236ee10f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1830000/1829100/1829043/21b8d40a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Panoramic Grand

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Panoramic-Grand.h1829043.Hotel-Information)

Puerto Iguazú

8.8/10

Excellent

(637 reviews)

"Friendly staff great breakfast amazing views, location near town "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stefania

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Panoramic-Grand.h1829043.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/ab97ae19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Triple Room | In-room safe, bed sheets](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/f17b57e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hallway](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/b6cde1ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/5000000/4050000/4041500/4041467/9788b105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marcopolo Suites Iguazu

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Marcopolo-Suites-Iguazu.h4041467.Hotel-Information)

Puerto Iguazú

6.6/10

(326 reviews)

"Clean, and close to the center of the city."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rodolfo

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Marcopolo-Suites-Iguazu.h4041467.Hotel-Information)

![Outdoor pool, open 9 AM to 7 PM, pool loungers](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/ca10ddeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dinner served, Argentinean cuisine, pool views ](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/5d6cd34f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite | Minibar, in-room safe, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/678479c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Double Room | Minibar, in-room safe, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/4000000/3470000/3469400/3469387/d7c44803.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Boutique Hotel Delafonte

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Boutique-Hotel-De-La-Fonte.h3469387.Hotel-Information)

Puerto Iguazú

8.6/10

Excellent

(364 reviews)

"Great location, good restaurant, nice pools, very responsive staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-Boutique-Hotel-De-La-Fonte.h3469387.Hotel-Information)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/7e00f6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/024260d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/90e69f9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/4000000/3240000/3235000/3234974/787572d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Aldea de la Selva Lodge

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-La-Aldea-De-La-Selva-Lodge.h3234974.Hotel-Information)

Puerto Iguazú

8.8/10

Excellent

(541 reviews)

"The architecture of the main lodge and the extensive grounds and pool area truly stood out. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Robin

£81

4 Mar - 5 Mar

[](https://www.expedia.co.uk/Puerto-Iguazu-Hotels-La-Aldea-De-La-Selva-Lodge.h3234974.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-17&endDate=2026-03-18&regionId=6208836&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

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## Find out more about Mesopotamia

### Mesopotamiaand its attractions for luxury travelers

Mesopotamia, Argentina, is a hidden gem for luxury travellers seeking both adventure and comfort. A visit to the stunning Ibera Wetlands offers the chance to witness extraordinary biodiversity, where you can arrange private guided tours to spot caimans, capybaras, and an array of exotic birds, all while enjoying a gourmet picnic amidst nature. The cultural richness of the region is evident in the charming town of Mercedes, where you can indulge in exclusive wine tastings at local vineyards known for their exquisite Malbecs, paired perfectly with delicious regional cuisine prepared by renowned chefs. For those interested in history, the archaeological site of San Ignacio Mini showcases the impressive Jesuit ruins, providing a fascinating glimpse into the past, complemented by a luxurious stay at nearby boutique hotels offering personalised service and modern amenities. The lush landscapes and tranquil rivers offer opportunities for private yacht excursions, where you can relax with champagne while soaking in the breathtaking scenery, providing a perfect blend of relaxation and exploration. For an ultimate experience, consider staying in the upscale lodges in the heart of the wetlands, where plush accommodations and attentive staff ensure you are pampered throughout your stay.

## Top Mesopotamia Hotel Reviews

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