Title: TOP Family-Friendly Hotels in Mesopotamia for 2026 - Mesopotamia Family Welcoming Hotels | Expedia.co.uk [Mesopotamia Travel Guide](https://expedia.co.uk/Mesopotamia.dx6208836)[Hotels in Mesopotamia](https://expedia.co.uk/Mesopotamia-Hotels.d6208836.Travel-Guide-Hotels)[Holiday Rentals in Mesopotamia](https://expedia.co.uk/Mesopotamia-Holiday-Rentals.d6208836.Travel-Guide-HolidayRentals)[Flights to Mesopotamia](https://expedia.co.uk/Cheap-Flights-To-Mesopotamia.d6208836.Travel-Guide-Flights)[Mesopotamia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesopotamia.d6208836.Car-Hire-Guide)[Mesopotamia Holidays](https://expedia.co.uk/Mesopotamia.d6208836.Holidays-City-Breaks) ![Iguazu Falls showing a cascade](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6171898/bb162948-b907-405b-9053-fc054127c668.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mesopotamia Family-Friendly Hotels Tonight [21 Jan - 22 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-01-21&endDate=2026-01-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Tomorrow [22 Jan - 23 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-01-22&endDate=2026-01-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) This weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) Next weekend [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6208836&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=family_friendly) ## Our top choices for Mesopotamia family-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/5a0bc70a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Triple Room, Park View | Minibar, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/5ce32c6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/b05a90aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120720000/120713200/120713176/8be36161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Regina Lodge [](https://www.expedia.co.uk/Municipo-De-Itati-Hotels-La-Regina-Lodge.h120713176.Hotel-Information) Municipo de Itati £51 22 Jan - 23 Jan [](https://www.expedia.co.uk/Municipo-De-Itati-Hotels-La-Regina-Lodge.h120713176.Hotel-Information) ![Children’s play area – indoor](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cee52cb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/a0c96e7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/d7aa541d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cf8e0206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hathor Concordia [](https://www.expedia.co.uk/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) Concordia 8.6/10 Excellent (364 reviews) "AC did not work well, food was OK. Staff friendly. Good hotel for a stay on the road." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patrick [](https://www.expedia.co.uk/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) ![Games room](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/7d07ca12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/6a6d02f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), body treatments, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/96c06c0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/37000000/36810000/36801000/36800965/f4e90853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Maran Suites & Towers - Hotel & Spa [](https://www.expedia.co.uk/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information) Parana 9.2/10 Wonderful (31 reviews) "Great location and friendly, accommodating staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £67 18 Feb - 19 Feb [](https://www.expedia.co.uk/Parana-Hotels-Maran-Suites-Towers-Hotel-Spa.h36800965.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/e90b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/fc0680d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/dd41bc20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room | Desk, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/34000000/33350000/33347000/33346911/a9efae27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel y Spa Termas del Este [](https://www.expedia.co.uk/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information) Federacion 8.4/10 Very good (12 reviews) "good for a 1 night stay" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Chase [](https://www.expedia.co.uk/Federacion-Hotels-Hotel-Y-Spa-Termas-Del-Este.h33346911.Hotel-Information) ![2 bedrooms, hypo-allergenic bedding, down duvets, in-room safe](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/2fdb89ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area | 32-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/758c5263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Private kitchen | Full-sized fridge, oven, stovetop, rice cooker](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/69bd66ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/34000000/33350000/33341500/33341429/f0f7bd93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Totoras Apart Federacion [](https://www.expedia.co.uk/Federacion-Hotels-Totoras-Apart-Federacion.h33341429.Hotel-Information) Federacion 7.4/10 Good (27 reviews) "Todo perfecto!!! " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Gabriel [](https://www.expedia.co.uk/Federacion-Hotels-Totoras-Apart-Federacion.h33341429.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/111000000/110440000/110434900/110434860/7a7e4c0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/111000000/110440000/110434900/110434860/ed8c82be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Quadruple Room | Living area | 32-inch LED TV with cable channels](https://images.trvl-media.com/lodging/111000000/110440000/110434900/110434860/fc0176c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Quadruple Room | Premium bedding, down duvets, in-room safe, desk](https://images.trvl-media.com/lodging/111000000/110440000/110434900/110434860/022b0c0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Hotel [](https://www.expedia.co.uk/Federacion-Hotels-Urban-Hotel.h110434860.Hotel-Information) Federacion 2.0/10 (1 review) "Ambiente deixa a desejar, muito sujo, café da manhã ruim, sem opção. Baratas no ambiente." ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) FABIO [](https://www.expedia.co.uk/Federacion-Hotels-Urban-Hotel.h110434860.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/4ee385b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/62c5f089.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/2c7dcd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/50000000/49090000/49086600/49086569/f5d9effc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Silos Hotel [](https://www.expedia.co.uk/Santa-Fe-Parana-Hotels-Los-Silos-Hotel.h49086569.Hotel-Information) Santa Fe 9.2/10 Wonderful (29 reviews) "Unique, interesting, and very nice. Staff was outstanding. We will be back soon" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Russell £81 25 Jan - 26 Jan [](https://www.expedia.co.uk/Santa-Fe-Parana-Hotels-Los-Silos-Hotel.h49086569.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/21000000/20270000/20265400/20265319/85927094.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/21000000/20270000/20265400/20265319/17682364.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/21000000/20270000/20265400/20265319/209ac113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/21000000/20270000/20265400/20265319/6db98c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dazzler by Wyndham Rosario [](https://www.expedia.co.uk/Rosario-Hotels-Dazzler-By-Wyndham-Rosario.h20265319.Hotel-Information) Rosario 8.8/10 Excellent (193 reviews) "Convenient if you like shopping and the hotel very good amenities " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Daniela £70 25 Jan - 26 Jan [](https://www.expedia.co.uk/Rosario-Hotels-Dazzler-By-Wyndham-Rosario.h20265319.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/5000000/4200000/4190200/4190115/7c543aae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4200000/4190200/4190115/7fc85867.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4200000/4190200/4190115/90a4ed49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4200000/4190200/4190115/54b6012c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Mision Posadas Hotel [](https://www.expedia.co.uk/Posadas-Hotels-La-Mision-Posadas-Hotel.h4190115.Hotel-Information) Posadas 7.8/10 Good (135 reviews) "I enjoyed the service I received from the staff, as well as the help with my suitcase up the stairs to my room. I loved the comfortable bed! Breakfast was limited, but adequate. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £39 22 Jan - 23 Jan [](https://www.expedia.co.uk/Posadas-Hotels-La-Mision-Posadas-Hotel.h4190115.Hotel-Information) ![Indoor pool, open 9:00 AM to 9:00 PM, pool loungers](https://images.trvl-media.com/lodging/73000000/72560000/72556200/72556112/420f84f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/73000000/72560000/72556200/72556112/f948db46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/73000000/72560000/72556200/72556112/8c80ae8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/73000000/72560000/72556200/72556112/71674033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mercure Hotel Rosario [](https://www.expedia.co.uk/Rosario-Hotels-Mercure-Hotel-Rosario.h72556112.Hotel-Information) Rosario 8.0/10 Very good (17 reviews) "Excellent option " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diego £56 19 Feb - 20 Feb [](https://www.expedia.co.uk/Rosario-Hotels-Mercure-Hotel-Rosario.h72556112.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-04&endDate=2026-02-05®ionId=6208836&adults=2&travelerType=family_friendly&sort=RECOMMENDED&openPlayBack=true) ## Choose what matters most at family-friendly hotels in Mesopotamia Breakfast included Pool Beach Restaurant Child care ## Top Mesopotamia Hotel Reviews ![Holiday Inn Express Rosario by IHG](https://images.trvl-media.com/lodging/4000000/3250000/3243000/3242923/502819d5_y.jpg) ### Holiday Inn Express Rosario by IHG 10/10 Excellent "Clean room. Very nice staffing. Very good breakfast " [](https://expedia.co.uk/Rosario-Hotels-Holiday-Inn-Express-Rosario.h3242923.Hotel-Information) ![Hathor Concordia](https://images.trvl-media.com/lodging/5000000/4670000/4668300/4668235/cc821f0d_y.jpg) ### Hathor Concordia 10/10 Excellent "The hotel staff is very polite Service: "Friendly and efficient," "helpful," "attentive," "welcoming smile," "professional"." [](https://expedia.co.uk/Concordia-Hotels-Hathor-Concordia.h4668235.Hotel-Information) ![Club Valle Termal Resort](https://images.trvl-media.com/lodging/12000000/11880000/11876000/11875903/afd7d710_y.jpg) ### Club Valle Termal Resort 10/10 Excellent "La habitación estaba impecable, la limpieza de todo el complejo fue excelente, pero quiero destacar la atención de todo su personal, la disponibilidad constante para atender todas nuestras necesidades. Lo recomiendo y espero poder volver pronto." [](https://expedia.co.uk/Federacion-Hotels-Club-Valle-Termal-Resort.h11875903.Hotel-Information) ![Wyndham Garden Campana](https://images.trvl-media.com/lodging/1000000/990000/983700/983698/1521535a_y.jpg) ### Wyndham Garden Campana 6/10 Okay "Televisor con problemas de funcionamiento. Ducha que baña todo el baño en lugar de ti. Ventana expuesta al paso de todo el público. " [](https://expedia.co.uk/Pilar-Hotels-Australis-Campana.h983698.Hotel-Information) ## Explore a world of travel with Expedia - More ways to book - [Book Family-Friendly Hotels in Mesopotamia on Expedia.com.ar ](https://www.expedia.com.ar/Mesopotamia-Hoteles-Hotel-Familiar.0-0-d6208836-tHotelfamiliar.Guia-filtrada-de-Hoteles)