Title: TOP Adults Only Resorts & Hotels in Mesilla, NM for 2026 | Expedia.co.uk [Hotels in Mesilla](https://expedia.co.uk/Mesilla-Hotels.d132684.Travel-Guide-Hotels)[Holiday Rentals in Mesilla](https://expedia.co.uk/Mesilla-Holiday-Rentals.d132684.Travel-Guide-HolidayRentals)[Mesilla Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesilla.d132684.Car-Hire-Guide)[Mesilla Holidays](https://expedia.co.uk/Mesilla.d132684.Holidays-City-Breaks) ![Red chile doorway Mesilla NM](https://images.trvl-media.com/place/132684/621c4b20-e7ee-452c-9495-0ec62a9d9908.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Adults Only Resorts & Hotels in Mesilla - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Mesilla Adults Only Resorts & Hotels Tonight [2 Dec - 3 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=132684&startDate=2025-12-02&endDate=2025-12-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [3 Dec - 4 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=132684&startDate=2025-12-03&endDate=2025-12-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) This weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=132684&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=132684&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Top Mesilla Adults Only Resorts & Hotels No exact matches found, but these alternatives could be just right ## Recommended hotels in Mesilla ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/5b5c1a96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/3f2542a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/67719f59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/679005c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Encanto de Las Cruces Las Cruces 9.0/10 Wonderful (1584) "We had a wonderful stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amber £112 includes taxes & fees 3 Dec - 4 Dec [](https://www.expedia.co.uk/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/34000000/34000000/33994100/33994040/w4000h2664x0y0-ac6ea18d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/34000000/34000000/33994100/33994040/b7ae0409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/34000000/34000000/33994100/33994040/8dc1a6d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/34000000/34000000/33994100/33994040/647b9147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Las Cruces at NMSU Las Cruces 9.4/10 Exceptional (503) "A very nice, clean, and convenient hotel. The food there was good too. I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Perry £107 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Las-Cruces-Hotels-Courtyard-By-Marriott-Las-Cruces.h33994040.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/a6b6426a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/6adba37c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/2816db98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/f6627f8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Las Cruces I-10 Las Cruces 8.8/10 Excellent (1001) "excellent hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nora E £84 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Las-Cruces-Hotels-Hampton-Inn-Suites-Las-Cruces-I-10.h12817768.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/203700/203622/ee15ba4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down duvets, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/210000/203700/203622/04b1b881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/210000/203700/203622/23254243.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Double Beds | Down duvets, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/210000/203700/203622/34baa6b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Springhill Suites By Marriott Las Cruces Las Cruces 8.4/10 Very good (950) "Would stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randy £81 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Las-Cruces-Hotels-Springhill-Suites-By-Marriott-Las-Cruces.h203622.Hotel-Information) ![Full-sized fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/18000000/17400000/17394300/17394207/fc66f953.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/18000000/17400000/17394300/17394207/w3837h2556x3y4-136ce3f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17400000/17394300/17394207/13109ba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17400000/17394300/17394207/w3837h2557x3y3-1f320837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Las Cruces Las Cruces 9.4/10 Exceptional (652) "Will definitely stay there again" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorena £94 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Las-Cruces-Hotels-Home2-Suites-By-Hilton-Las-Cruces.h17394207.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/11000000/10330000/10320300/10320201/c5bb6ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking | Pillow-top beds, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/11000000/10330000/10320300/10320201/bf4a0d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/11000000/10330000/10320300/10320201/a92d487e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10330000/10320300/10320201/eae97133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Las Cruces I-25 North Las Cruces 9.2/10 Wonderful (1000) "Great location great breakfast friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly £99 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/Las-Cruces-Hotels-Comfort-Suites-Las-Cruces-I-25-North.h10320201.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43200/43179/3f986bbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Non Smoking | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/50000/43200/43179/167f8809.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/43200/43179/6fedabd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/43200/43179/bfda582c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites University Las Cruces Las Cruces 8.0/10 Very good (1007) "Amazing staff, clean rooms, great breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle £69 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Las-Cruces-Hotels-Comfort-Suites-University-Las-Cruces.h43179.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/90d9a325.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/269dd61d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/89e377bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/b11dfff8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Mission Inn Las Cruces 8.8/10 Excellent (1229) "Very comfortable place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maryann £71 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Las-Cruces-Hotels-Best-Western-Mission-Inn.h20506.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1650000/1647600/1647510/1ac5e06e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1650000/1647600/1647510/e1017db2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1650000/1647600/1647510/49f03181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1650000/1647600/1647510/eaecc7d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel and Suites Las Cruces by IHG Las Cruces 7.8/10 Good (1000) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Martin and Nancy £83 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/Las-Cruces-Hotels-Holiday-Inn-Express-Hotel-And-Suites-Las-Cruces.h1647510.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353805/518ac77c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353805/49939edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353805/8e674089.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353805/cb4746b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Las Cruces Mesilla Las Cruces 8.8/10 Excellent (1000) "Nice place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) chris £87 includes taxes & fees 5 Dec - 6 Dec [](https://www.expedia.co.uk/Las-Cruces-Hotels-Comfort-Inn-Suites-Las-Cruces-Mesilla.h1353805.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-16&endDate=2025-12-17®ionId=132684&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_BF_PROMO_132684) ## Top Mesilla Hotel Reviews ## Frequently asked questions ### How much do adults-only hotels in Mesilla cost? > Adults-only properties in Mesilla can be found in a range of prices depending on the amenities provided and the type of room you book. Whatever you decide on, you can have all the youngster-free tranquility you want at a price that doesn't break the bank. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Gay-Friendly Hotels in Alamogordo](https://www.expedia.co.uk/Alamogordo-Hotels-Gay-Friendly-Hotel.0-0-d6054974-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Anthony Hotels](https://www.expedia.co.uk/Anthony-Hotels.d6140995.Travel-Guide-Hotels) - [Caballo Hotels](https://www.expedia.co.uk/Caballo-Hotels.d3000447695.Travel-Guide-Hotels) - [Chaparral Hotels](https://www.expedia.co.uk/Chaparral-Hotels.d3000350231.Travel-Guide-Hotels) - [Hotels near Chile Pepper Institute](https://www.expedia.co.uk/Chile-Pepper-Institute-Hotels.0-l553248621533114173-0.Travel-Guide-Filter-Hotels) - [Columbus Hotels](https://www.expedia.co.uk/Columbus-Hotels.d91634.Travel-Guide-Hotels) - [Deming Hotels](https://www.expedia.co.uk/Deming-Hotels.d6833.Travel-Guide-Hotels) - 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[Flights to Las Cruces](https://www.expedia.co.uk/Cheap-Flights-To-Las-Cruces.d2137.Travel-Guide-Flights) - [Flights to Sunland Park](https://www.expedia.co.uk/Cheap-Flights-To-Sunland-Park.d6354940.Travel-Guide-Flights) - [Flights to Truth or Consequences](https://www.expedia.co.uk/Cheap-Flights-To-Truth-Or-Consequences.d10038.Travel-Guide-Flights) - [Flights to White Sands](https://www.expedia.co.uk/Cheap-Flights-To-White-Sands.d6208412.Travel-Guide-Flights) - [Flights from White Sands Regional](https://www.expedia.co.uk/lp/airports/alm/flights-from-white-sands-regional-airport) - [Flights from Las Cruces Intl.](https://www.expedia.co.uk/lp/airports/lru/flights-from-las-cruces-intl-airport) - [Flights from Vado](https://www.expedia.co.uk/lp/flights/3000447949/flights-from-vado) - [Flights from Anthony](https://www.expedia.co.uk/lp/flights/6140995/flights-from-anthony) - [Flights from White Sands](https://www.expedia.co.uk/lp/flights/6208412/flights-from-white-sands) - [Flights from Sunland Park](https://www.expedia.co.uk/lp/flights/6354940/flights-from-sunland-park) - 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[Visit Sunland Park](https://www.expedia.co.uk/Sunland-Park.dx6354940) - [Truth or Consequences Holidays](https://www.expedia.co.uk/Truth-Or-Consequences.d10038.Holidays-City-Breaks) - [Visit Truth or Consequences](https://www.expedia.co.uk/Truth-Or-Consequences.dx10038) - [White Sands National Park](https://www.expedia.co.uk/White-Sands-National-Park-New-Mexico.d6093661.Attraction) - [Alamo Rent A Car Rental Cars in Santa Teresa](https://www.expedia.co.uk/Alamo-Rent-A-Car-Car-Rentals-In-Santa-Teresa.d6337326-c6.Car-Rental-Guide-Suppliers) - [Rental cars Las Cruces Intl. airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Las-Cruces-Intl.d5591628.Car-Hire-Guide) - [Car hire Las Cruces](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Las-Cruces.d2137.Car-Hire-Guide) - [Car hire Truth or Consequences](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Truth-Or-Consequences.d10038.Car-Hire-Guide) - [Essence Car Rental Rental Cars in Organ Mountains Desert Peaks National Monument](https://www.expedia.co.uk/Essence-Car-Rental-Car-Rentals-In-Organ-Mountains-Desert-Peaks-National-Monument.d553248635998039563-c1085.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Truth or Consequences](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Truth-Or-Consequences.d10038-c40.Car-Rental-Guide-Suppliers) - [Minivan Car Hire near White Sands National Park](https://www.expedia.co.uk/Minivan-Car-Rentals-In-White-Sands-National-Park.d6093661-tMinivan.Car-Rental-Guide-Class) - [People Carrier Car Hire near White Sands National Park](https://www.expedia.co.uk/Van-Car-Rentals-In-White-Sands-National-Park.d6093661-tVan.Car-Rental-Guide-Class) - [Las Cruces Holiday Rentals](https://www.expedia.co.uk/Las-Cruces-Holiday-Rentals.d2137.Travel-Guide-HolidayRentals) - [Truth or Consequences Holiday Rentals](https://www.expedia.co.uk/Truth-Or-Consequences-Holiday-Rentals.d10038.Travel-Guide-HolidayRentals) - [Things to do in Las Cruces](https://www.expedia.co.uk/Things-To-Do-In-Las-Cruces.d2137.Travel-Guide-Activities) - [Book Adults Only Resorts & Hotels in Mesilla on Expedia.com](https://www.expedia.com/Mesilla-Hotels-Adults-Only-Resorts.0-0-d132684-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)