Title: Holiday Rentals Mesilla from £103: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Hotels in Mesilla](https://expedia.co.uk/Mesilla-Hotels.d132684.Travel-Guide-Hotels)[Mesilla Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesilla.d132684.Car-Hire-Guide)[Mesilla Holidays](https://expedia.co.uk/Mesilla.d132684.Holidays-City-Breaks) ![Red chile doorway Mesilla NM](https://images.trvl-media.com/place/132684/621c4b20-e7ee-452c-9495-0ec62a9d9908.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/132684/621c4b20-e7ee-452c-9495-0ec62a9d9908.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=132684&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [22 May - 24 May](https://www.expedia.co.uk/Hotel-Search?regionId=132684&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [19 Jun - 21 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=132684&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [17 Jul - 19 Jul](https://www.expedia.co.uk/Hotel-Search?regionId=132684&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mesilla holiday rentals ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/bc0a9d00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/7d2a99cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/02adc68a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/1aa64a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Cruces Home w/ Fenced Yard: Recently Remodeled [](https://www.expedia.co.uk/Las-Cruces-Hotels-Las-Cruces-Home-W-Fenced-Yard-Recently-Remodeled.h119923794.Hotel-Information) Las Cruces 10/10 Exceptional (1 review) "The host was thoughful. He provided all the information we needed and responded our questions really quickly. The house was clean and very well organized. This house had the best view at night. We will definitely visit again when we go Santa fe. 😊 " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nam £193 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/Las-Cruces-Hotels-Las-Cruces-Home-W-Fenced-Yard-Recently-Remodeled.h119923794.Hotel-Information) ![House, 2 Bedrooms | Living area | Smart TV, streaming services](https://images.trvl-media.com/lodging/121000000/120410000/120402300/120402249/043ded28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, 2 Bedrooms | Living area | Smart TV, streaming services](https://images.trvl-media.com/lodging/121000000/120410000/120402300/120402249/b70818bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, 2 Bedrooms | Interior](https://images.trvl-media.com/lodging/121000000/120410000/120402300/120402249/a0826640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, 2 Bedrooms | Living area | Smart TV, streaming services](https://images.trvl-media.com/lodging/121000000/120410000/120402300/120402249/097df6e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Desert Haven Cozy 2-Bedroom Mobile Home Near NMSU 2 Home [](https://www.expedia.co.uk/Las-Cruces-Hotels-Desert-Haven-Cozy-2-Bedroom-Mobile-Home-Near-NMSU-2-Home.h120402249.Hotel-Information) Las Cruces £289 includes taxes & fees 7 Apr - 8 Apr [](https://www.expedia.co.uk/Las-Cruces-Hotels-Desert-Haven-Cozy-2-Bedroom-Mobile-Home-Near-NMSU-2-Home.h120402249.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-13&endDate=2026-04-14®ionId=132684&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-06-27&d1=2026-06-27&endDate=2026-06-30&d2=2026-06-30&lodging=APARTMENT) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-06-27&d1=2026-06-27&endDate=2026-06-30&d2=2026-06-30&lodging=VACATION_HOME) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-06-27&d1=2026-06-27&endDate=2026-06-30&d2=2026-06-30&lodging=COTTAGE) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-06-27&d1=2026-06-27&endDate=2026-06-30&d2=2026-06-30&lodging=CONDO) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=132684&latLong=32.270096%2C-106.800835&adults=2&startDate=2026-06-27&d1=2026-06-27&endDate=2026-06-30&d2=2026-06-30&lodging=VILLA) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesilla-Holiday-Rentals.d132684.Travel-Guide-HolidayRentals)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesilla-Holiday-Rentals.d132684.Travel-Guide-HolidayRentals) ## Top Mesilla Hotel Reviews ![Hotel Encanto de Las Cruces](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/5b5c1a96_y.jpg) ### Hotel Encanto de Las Cruces 4/10 Poor "Place looked nice. Had ants in the bathroom. Sink was still dirty with a nat and hairs with what looked like sand. Smelled like fetta. There were kids in the hot tub until it closed. You have to hike a hill if the upper parking lot and handicapped spaces are full, with a lot of cars with no placard or plates. No conceirge to help. No carts to assist. So keep circling. Fitness room was good. " [](https://expedia.co.uk/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain](https://images.trvl-media.com/lodging/1000000/80000/75400/75365/e54f14db_y.jpg) ### La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain 2/10 Terrible "The breakfast was terrible. Noisy stomping in adjacent rooms. Unfriendly staff. Will never stay there again." [](https://expedia.co.uk/Las-Cruces-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Las-Cruces-Organ-Mountain.h75365.Hotel-Information) ![Ramada Hotel & Conference Center by Wyndham Las Cruces](https://images.trvl-media.com/lodging/1000000/10000/3900/3871/1a82ee39_y.jpg) ### Ramada Hotel & Conference Center by Wyndham Las Cruces 8/10 Good "The staff was very friendly and helpful. The room was spacious and clean. " [](https://expedia.co.uk/Las-Cruces-Hotels-Ramada-Hotel-Conference-Center-By-Wyndham-Las-Cruces.h3871.Hotel-Information) ![Comfort Inn & Suites Las Cruces Mesilla](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353805/518ac77c_y.jpg) ### Comfort Inn & Suites Las Cruces Mesilla 4/10 Poor "Room had stains on curtains and bedding. Shower did not get hot. Roaches in the pool" [](https://expedia.co.uk/Las-Cruces-Hotels-Comfort-Inn-Suites-Las-Cruces-Mesilla.h1353805.Hotel-Information) ![Quality Inn & Suites Las Cruces - University Area](https://images.trvl-media.com/lodging/1000000/50000/43200/43177/04c2427f_y.jpg) ### Quality Inn & Suites Las Cruces - University Area 2/10 Terrible "I absolutely do not recommend this property. I arrived late on a Friday night, and was assigned and occupied room. When I notified the desk and they gave me another room, that one was occupied as well. By this time it was 10 o’clock at night, and the guest staying in the second room was angry. Understandably so. It put me in a very uncomfortable and unsafe situation. When I refuse to try a third room and request requested a refund, my request was not honored. It’s been two days, and I have not yet heard from the daytime manager. Very, very disappointed." [](https://expedia.co.uk/Las-Cruces-Hotels-Quality-Inn-Suites-Las-Cruces-University-Area.h43177.Hotel-Information) ![Hampton Inn & Suites Las Cruces I-25](https://images.trvl-media.com/lodging/2000000/1670000/1665200/1665185/fc08ee64_y.jpg) ### Hampton Inn & Suites Las Cruces I-25 6/10 Okay "Swimming pool was very cold. Front desk staff not very friendly. " [](https://expedia.co.uk/Las-Cruces-Hotels-Hampton-Inn-Suites-Las-Cruces-I-25.h1665185.Hotel-Information) ![Days Inn by Wyndham Las Cruces](https://images.trvl-media.com/lodging/1000000/20000/15100/15035/b4a415ed_y.jpg) ### Days Inn by Wyndham Las Cruces 10/10 Excellent "Yes, excellent!!" [](https://expedia.co.uk/Las-Cruces-Hotels-Days-Inn-By-Wyndham-Las-Cruces.h15035.Hotel-Information) ![Drury Inn & Suites Las Cruces](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723204/46263956_y.jpg) ### Drury Inn & Suites Las Cruces 10/10 Excellent "The property was nice, our room was large and clean, breakfast was delightful, pool and hot tub were nice and well-maintained. They were cleaning up from a flood induced by I guess over filling their tub recently, but everything wasn’t working order for us and quite nice." [](https://expedia.co.uk/Las-Cruces-Hotels-Drury-Inn-Suites-Las-Cruces.h1723204.Hotel-Information) ![Comfort Suites University Las Cruces](https://images.trvl-media.com/lodging/1000000/50000/43200/43179/3f986bbe_y.jpg) ### Comfort Suites University Las Cruces 2/10 Terrible "No hot water was unable to shower nothing was done to compensate customers rude staff" [](https://expedia.co.uk/Las-Cruces-Hotels-Comfort-Suites-University-Las-Cruces.h43179.Hotel-Information) ## Find out more about Mesilla **Everything you need to know about** **Mesilla** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Mesilla holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesilla holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Mesilla holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Mesilla. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Mesilla holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Mesilla holiday rentals we have selected for you start as low as £103 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Mesilla rentals** At Expedia, we put the best Mesilla holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Mesilla rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesilla holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesilla. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.co.uk ### Trending destinations on Expedia.co.uk - [Holiday Rentals in the Cotswold ](https://www.expedia.co.uk/lp/b/vr/cotswold) - [Holiday Rentals in Lake District ](https://www.expedia.co.uk/lp/b/vr/lake-district) - [Devon Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Devon.d6046196.Holiday-Rental-Destinations) - [Norfolk Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Norfolk.d6046223.Holiday-Rental-Destinations) - [Bedfordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Bedfordshire.d6046189.Holiday-Rental-Destinations) - [Dorset Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Dorset.d6046198.Holiday-Rental-Destinations) - [Northumberland Holiday Rentals ](https://www.expedia.com/Destinations-In-Northumberland.d6046225.Vacation-Rental-Destinations) - [Herefordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Herefordshire.d6046203.Holiday-Rental-Destinations) - [Essex Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Essex.d6046201.Holiday-Rental-Destinations) - [Cumbria Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cumbria.d6046194.Holiday-Rental-Destinations) - [Yorkshire Holiday Rentals ](https://www.expedia.co.uk/Yorkshire-Holiday-Rentals.d6342462.Travel-Guide-HolidayRentals) - [South Wales Holiday Rentals ](https://www.expedia.co.uk/South-Wales-Holiday-Rentals.d6054274.Travel-Guide-HolidayRentals) - [North Wales Holiday Rentals ](https://www.expedia.co.uk/North-Wales-Holiday-Rentals.d6054276.Travel-Guide-HolidayRentals) - [London Holiday Rentals ](https://www.expedia.co.uk/London-Holiday-Rentals.d178279.Travel-Guide-HolidayRentals) - [York Holiday Rentals ](https://www.expedia.co.uk/York-Holiday-Rentals.d5489.Travel-Guide-HolidayRentals) - [Blackpool Holiday Rentals ](https://www.expedia.co.uk/Blackpool-Holiday-Rentals.d619.Travel-Guide-HolidayRentals) - [Isle of Wight Holiday Rentals ](https://www.expedia.com/Destinations-In-Isle-Of-Wight.d6046218.Vacation-Rental-Destinations) - [Scarborough Holiday Rentals ](https://www.expedia.co.uk/Scarborough-Holiday-Rentals.d5680.Travel-Guide-HolidayRentals) - [Edinburgh Holiday Rentals ](https://www.expedia.co.uk/Edinburgh-Holiday-Rentals.d6069845.Travel-Guide-HolidayRentals) - [Bath Holiday Rentals ](https://www.expedia.co.uk/Bath-Holiday-Rentals.d6084496.Travel-Guide-HolidayRentals) - [Bournemouth Holiday Rentals ](https://www.expedia.co.uk/Bournemouth-Holiday-Rentals.d654.Travel-Guide-HolidayRentals) - [England Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-England.d11218.Holiday-Rental-Destinations) - [Scotland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Scotland.d11219.Holiday-Rental-Destinations) - [Cornwall Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cornwall.d6046193.Holiday-Rental-Destinations) - [Wales Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations) - [Northern Ireland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations) ## Frequently asked questions ### Can I find a holiday rental in Mesilla? ### What are some of the best holiday rentals that Mesilla has to offer? ### How many holiday rentals will I find in Mesilla? ### What’s there to see and do in Mesilla? ### What’s a holiday rental in Mesilla like?