Title: La Villa de los Santos Holidays 2026 from £719 | Expedia.co.uk [Hotels in La Villa de los Santos](https://expedia.co.uk/La-Villa-De-Los-Santos-Hotels.d553248623140686317.Travel-Guide-Hotels)[Holiday Rentals in La Villa de los Santos](https://expedia.co.uk/La-Villa-De-Los-Santos-Holiday-Rentals.d553248623140686317.Travel-Guide-HolidayRentals)[La Villa de los Santos Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Villa-De-Los-Santos.d553248623140686317.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # La Villa de los Santos Holidays from £719 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected #### Your La Villa de los Santos Holiday You'll find plenty to love about La Villa de los Santos, from its cultural experiences to its rich history. When you're ready to spend a bit of time in this wonderful city, our La Villa de los Santos holiday packages will be right up your alley. [Playa El Rompio](https://www.expedia.co.uk/Playa-El-Rompio-Los-Santos.d3000441876.Attraction), [Museo de la Nacionalidad](https://www.expedia.co.uk/Museo-De-La-Nacionalidad-La-Villa-de-los-Santos.d553248621532964470.Attraction) and [Church of St. Athanasius](https://www.expedia.co.uk/Church-Of-St-Athanasius-La-Villa-de-los-Santos.d553248621532964471.Attraction) are just a few of the sights worth visiting during your trip to La Villa de los Santos. Your ultimate La Villa de los Santos holiday is only clicks away. Browse hotels, flights and more on Expedia for an adventure that's tailored just for you. ## Top La Villa de los Santos Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mahogany Suites £719 per person 7 May - 12 May found 1 day ago Return direct flight included London (LHR) to Panama City (PTY) 10/10 Exceptional! (1 review) Excellent apartment on a golf resort. 5 Star. Reviewed on 28 Jan 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo £1,064 per person 7 May - 12 May found 1 day ago Return direct flight included London (LHR) to Panama City (PTY) 9/10 Wonderful! (1,002 reviews) The room had no window to the outside it instead had a large window into an interior hall. Maid service was inconsistent. Breakfast was not a good value. Reviewed on 5 Feb 2026 ![Casa Mallet by Wynwood House](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Mallet by Wynwood House Casco Viejo £1,006 per person 26 Mar - 1 Apr found 12 hours ago Return flight included Montego Bay (MBJ) to Panama City (PTY) 9.8/10 Exceptional! (24 reviews) Beautiful apartment definitely recommend staying here if you are coming to Panama Reviewed on 29 Nov 2025 ![Casa Contemporanea by Wynwood House](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/64939a66_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Contemporanea by Wynwood House Casco Viejo £917 per person 26 Mar - 1 Apr found 12 hours ago Return flight included Montego Bay (MBJ) to Panama City (PTY) 8.6/10 Excellent! (19 reviews) Great experience, beautiful apartment. Minor maintenance issues that were addressed in a timely fashion. Would definitely recommend and stay there again! Reviewed on 28 Mar 2025 ![Yoo by Wynwood House](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/f526e4da_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Yoo by Wynwood House Calidonia £914 per person 26 Mar - 1 Apr found 12 hours ago Return flight included Montego Bay (MBJ) to Panama City (PTY) 9.2/10 Wonderful! (5 reviews) Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone. Reviewed on 26 Jul 2025 ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=PKG_SPRING_PROMO_553248623140686317) ## La Villa de los Santos Essential Information | Language | Spanish | | --------------- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Panamanian balboas | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Closest Airport | Chitre (CTD-Alonso Valderrama) | | Max Temp Winter | 29ºC | | Max Temp Summer | 29ºC | | Top Sights | [Playa El Rompio](https://www.expedia.co.uk/Playa-El-Rompio-Los-Santos.d3000441876.Attraction), [Museo de la Nacionalidad](https://www.expedia.co.uk/Museo-De-La-Nacionalidad-La-Villa-de-los-Santos.d553248621532964470.Attraction) and [Church of St. Athanasius](https://www.expedia.co.uk/Church-Of-St-Athanasius-La-Villa-de-los-Santos.d553248621532964471.Attraction) | ## Top hotels in La Villa de los Santos ![Voyager Int l Hostel Panama La Villa ](https://images.trvl-media.com/lodging/96000000/95450000/95446300/95446281/1f2474e1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Voyager Int l Hostel Panama La Villa Sergio Gonzales ruiz y 10 de Noviembre La Villa de los Santos Los Santos [Get rates](https://expedia.co.uk/Hotel-Search?startDate=26%2F02%2F2026&endDate=27%2F02%2F2026&selected=95446281&PinnedHotelID=95446281&HadPinnedHotel=true®ionId=553248623140686317) [](https://expedia.co.uk/Hotel-Search?startDate=26%2F02%2F2026&endDate=27%2F02%2F2026&selected=95446281&PinnedHotelID=95446281&HadPinnedHotel=true®ionId=553248623140686317) ![Hotel Faranda Guayacanes, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/980000/971000/970914/2fd85024_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Faranda Guayacanes, a member of Radisson Individuals Via Circunvalacion S/n Chitre Herrera Fully refundableReserve now, pay when you stay £59 19 Feb - 20 Feb includes taxes & fees 7.8/10 Good! (304 reviews) Room was spotless. It was very small but ok for an over night stay. Dinner in the restaurant was excellent. Seafood casserole was too top notch. Breakfast was good too. Reviewed on 6 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=19%2F02%2F2026&endDate=20%2F02%2F2026&selected=970914&PinnedHotelID=970914&HadPinnedHotel=true®ionId=553248623140686317) ![Hotel Cubitá Boutique Resort & Spa](https://images.trvl-media.com/lodging/10000000/9680000/9675400/9675316/9ea589c5_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Cubitá Boutique Resort & Spa Ave. Roberto Ramirez de Diego La Arena Herrera 8.6/10 Excellent! (488 reviews) The rooms / bathrooms need a good cleaning and need to inspected before delivering them to the client . The service and food and employees are great !! Reviewed on 7 Feb 2026 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=26%2F02%2F2026&endDate=27%2F02%2F2026&selected=9675316&PinnedHotelID=9675316&HadPinnedHotel=true®ionId=553248623140686317) [](https://expedia.co.uk/Hotel-Search?startDate=26%2F02%2F2026&endDate=27%2F02%2F2026&selected=9675316&PinnedHotelID=9675316&HadPinnedHotel=true®ionId=553248623140686317) [See all 31 properties in La Villa de los Santos](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=13%2F02%2F2026&endDate=14%2F02%2F2026®ionId=553248623140686317) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app