Title: Cheap Car Hire in La Villa de los Santos, PAN - Expedia.co.uk [La Villa de los Santos Travel Guide](https://expedia.co.uk/La-Villa-De-Los-Santos.dx553248623140686317)[Hotels in La Villa de los Santos](https://expedia.co.uk/La-Villa-De-Los-Santos-Hotels.d553248623140686317.Travel-Guide-Hotels)[Flights to La Villa de los Santos](https://expedia.co.uk/Cheap-Flights-To-La-Villa-De-Los-Santos.d553248623140686317.Travel-Guide-Flights)[Things to do in La Villa de los Santos](https://expedia.co.uk/Things-To-Do-In-La-Villa-De-Los-Santos.d553248623140686317.Travel-Guide-Activities)[La Villa de los Santos Holidays](https://expedia.co.uk/La-Villa-De-Los-Santos.d553248623140686317.Holidays-City-Breaks) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_car.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in La Villa de los Santos, PAN ## Search and Compare from Car Companies in La Villa de los Santos ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in La Villa de los Santos \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people La Villa de los Santos, Los Santos, PAN ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=La%20Villa%20de%20los%20Santos,%20Los%20Santos,%20Panama&dpln=553248623140686317&date1=19/02/2026&date2=21/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people La Villa de los Santos, Los Santos, PAN ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=La%20Villa%20de%20los%20Santos,%20Los%20Santos,%20Panama&dpln=553248623140686317&date1=19/02/2026&date2=21/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people La Villa de los Santos, Los Santos, PAN ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=La%20Villa%20de%20los%20Santos,%20Los%20Santos,%20Panama&dpln=553248623140686317&date1=19/02/2026&date2=21/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people La Villa de los Santos, Los Santos, PAN ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=La%20Villa%20de%20los%20Santos,%20Los%20Santos,%20Panama&dpln=553248623140686317&date1=19/02/2026&date2=21/02/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in La Villa de los Santos [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=La%20Villa%20de%20los%20Santos,%20Los%20Santos,%20Panama&dpln=553248623140686317&date1=19/02/2026&date2=21/02/2026&crfrr=defaultFlex&SearchType=Place) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=CTG_SPRING_PROMO_553248623140686317) ## Frequently asked questions ### How much is a rental car per day in La Villa de los Santos? ### What happens if I need to cancel my La Villa de los Santos car reservation? ### What types of cars can I rent in La Villa de los Santos? ### Where can I go on a road trip from La Villa de los Santos? > - You'll feel the rhythm of bustling city life as soon as you pull into San Miguelito. Some 100 miles from La Villa de los Santos, it's home to a number of excellent spots to visit, such as Metromall Panama. > - Around 100 miles away, Colon is another location worth sticking on your travel itinerary. Be sure to check out Colon 2000 while you're there. > - No road trip is complete without exploring Red Frog Beach. This renowned nature spot is approximately 150 miles from La Villa de los Santos. Breathe in the fresh air and relax! ### How do I find the best car hire deals in La Villa de los Santos with Expedia? ### What do you need to rent a car in La Villa de los Santos? ### What is the cheapest car hire in La Villa de los Santos? ### Can I hire a car for a month or longer in La Villa de los Santos? ### Where can I find a La Villa de los Santos hire car if I am younger than 25? ### Why should I rent a La Villa de los Santos car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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