Title: The Best Aparthotels in La Mesa | Expedia.co.uk [Hotels in La Mesa](https://expedia.co.uk/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[Holiday Rentals in La Mesa](https://expedia.co.uk/La-Mesa-Holiday-Rentals.d8484.Travel-Guide-HolidayRentals)[La Mesa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Mesa.d8484.Car-Hire-Guide)[La Mesa Holidays](https://expedia.co.uk/La-Mesa.d8484.Holidays-City-Breaks) ![View from Mount Helix, in La Mesa, near San Diego, California](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search La Mesa Aparthotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2026-01-09&endDate=2026-01-11&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2026-01-16&endDate=2026-01-18&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2026-01-30&endDate=2026-02-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for La Mesa aparthotels ![Premium bedding, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b82a5191.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/dd5fc603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/112e5b86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/w2000h1293x0y90-00acac65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Gaslamp Quarter [](https://www.expedia.co.uk/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) Downtown San Diego 9.2/10 Wonderful (619) "Everything was splendid. Very friendly staff as well. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Irving £116 includes taxes & fees 5 Jan - 6 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/f051791c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/4195877c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/84cf0a12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/87b3eb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uptown Inn by Vantaggio - Limited Service Apart-Hotel [](https://www.expedia.co.uk/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) Hillcrest 8.4/10 Very good (271) "Overall good place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Isaac £82 includes taxes & fees 5 Jan - 6 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/79e8f033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/1b9a69bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bayview Condo - 2BR/3BA - Bunk Bed & Sofa Bed | Living area | 32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/48c0125d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6c7bbd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City24 Hotel Little Italy Mission Hills [](https://www.expedia.co.uk/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) Middletown 9.6/10 Exceptional (108) "would definitely go back and stay there again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kounwick [](https://www.expedia.co.uk/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) ![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/0f983451.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Private kitchen | Mini-fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/fbd31f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, microwave, stovetop, electric kettle](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/10234b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/26d61c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Gaslamp Quarter San Diego [](https://www.expedia.co.uk/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information) Downtown San Diego 8.0/10 Very good (154) "Everything was perfect about the room and location. The minor flaw was the stench in the lobby from the downstairs restaurant and bar. I loved staying here. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris [](https://www.expedia.co.uk/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/aa0ca94d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Apartment, 2 Bedrooms | Individually decorated, individually furnished, iron/ironing board](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/ad340e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/9ea3f4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms, Bay View (QueenBed) | Balcony view](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/f6cadddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Little Italy San Diego [](https://www.expedia.co.uk/San-Diego-Hotels-Kasa-Little-Italy-San-Diego.h108772597.Hotel-Information) Downtown San Diego 9.6/10 Exceptional (359) "Clean room, Kitchen was fully equipped. Had a great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miranda £230 includes taxes & fees 5 Jan - 6 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Kasa-Little-Italy-San-Diego.h108772597.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-18&endDate=2026-01-19®ionId=8484&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Apart-Hotels.d8484-aaApartHotels.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Apart-Hotels.d8484-aaApartHotels.Travel-Guide-Accommodation) ## Top La Mesa Hotel Reviews ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Bernard was very helpful and made my wife & my vacation extra memorable!" [](https://expedia.co.uk/San-Diego-Hotels-Sheraton-San-Diego-Resort.h11109.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "It was nice area and comfortable place. " [](https://expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](https://images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "Room was nice clean and tidy. Everything was excellent and extremely good." [](https://expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "Good " [](https://expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Marriott Marquis San Diego Marina](https://images.trvl-media.com/lodging/1000000/30000/24400/24394/9078a9ee_y.jpg) ### Marriott Marquis San Diego Marina 10/10 Excellent "Excellent service " [](https://expedia.co.uk/San-Diego-Hotels-Marriott-Marquis-San-Diego-Marina.h24394.Hotel-Information) ![Courtyard by Marriott San Diego Downtown Little Italy](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/db3040ff_y.jpg) ### Courtyard by Marriott San Diego Downtown Little Italy 10/10 Excellent "The big surprise is the Saturday farmers market right around the corner—such a great location!" [](https://expedia.co.uk/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![San Diego Mission Bay Resort](https://images.trvl-media.com/lodging/1000000/30000/25600/25598/bbcdbd6d_y.jpg) ### San Diego Mission Bay Resort 10/10 Excellent "We love this property!! This was our 2nd time staying. We booked for NYE, which although it was raining, we were still able to enjoy the jacuzzi. Check in was smooth, and you can’t beat the location. Still close to the liveliness of downtown, and old town, but quiet enough for a nice getaway. The bay view is gorgeous, and the christmas tree light up from Seaworld was a nice surprise. Definitely recommend this property. The only downfall being the $45/ night parking. We will be back in the summer for full usage! " [](https://expedia.co.uk/San-Diego-Hotels-San-Diego-Mission-Bay-Resort.h25598.Hotel-Information) ![Pendry San Diego](https://images.trvl-media.com/lodging/17000000/16300000/16299000/16298963/05d0e601_y.jpg) ### Pendry San Diego 10/10 Excellent "The room was clean, tasteful, and quiet. The staff was very friendly and helpful. We had a wonderful time in Pendry." [](https://expedia.co.uk/San-Diego-Hotels-Pendry-San-Diego.h16298963.Hotel-Information) ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "Check in was easy and fast, staff were friendly and helpful." [](https://expedia.co.uk/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ## Find out more about La Mesa ## La Mesa Serviced Apartments information | Number of reviews | 1,497 | | ----------------- | ---------------------- | | Accommodation | 39 Serviced Apartments | | Lowest Price | £82 | | Highest Price | £230 | ## Frequently asked questions ### What can I look forward to during my La Mesa aparthotel stay? ### What are visitors' favourite aparthotels for my stay in La Mesa? ### How many aparthotels will I find in La Mesa? ### What should I see in La Mesa? ### What is an aparthotel? ## Explore a world of travel with Expedia - More ways to book - [Book Serviced Apartments in La Mesa on Expedia.com ](https://www.expedia.com/La-Mesa-Apart-Hotels.d8484-aaApartHotels.Travel-Guide-Accommodation)