Title: The Best Aparthotels in La Mesa | Expedia.co.uk [Hotels in La Mesa](https://expedia.co.uk/La-Mesa-Hotels.d8484.Travel-Guide-Hotels)[Holiday Rentals in La Mesa](https://expedia.co.uk/La-Mesa-Holiday-Rentals.d8484.Travel-Guide-HolidayRentals)[La Mesa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Mesa.d8484.Car-Hire-Guide)[La Mesa Holidays](https://expedia.co.uk/La-Mesa.d8484.Holidays-City-Breaks) ![View from Mount Helix, in La Mesa, near San Diego, California](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/8484/0fa3bc38-9bbb-4533-9232-a1a6e7720bc2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [1 May - 3 May](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [29 May - 31 May](https://www.expedia.co.uk/Hotel-Search?regionId=8484&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for La Mesa aparthotels ![Lobby sitting area](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/f051791c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/e8d02919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Room, 1 Queen Bed (East - Freeway Facing) | Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/61427440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/b278e0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uptown Inn by Vantaggio - Limited Service Apart-Hotel [](https://www.expedia.co.uk/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) Hillcrest 8.4/10 Very good (290 reviews) "The room was very small but very clean. Great place to stay for the short amount of time we needed it. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra £83 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/dd5fc603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/9a181764.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | Premium bedding, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b4a5f1e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/6521c599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sentral Gaslamp Quarter [](https://www.expedia.co.uk/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) Downtown San Diego 9.4/10 Exceptional (670 reviews) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KELLY £136 includes taxes & fees 12 Feb - 13 Feb [](https://www.expedia.co.uk/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information) ![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/834f95c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/bc47b23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | In-room dining](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/3636bd40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/4bb2e41a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Gaslamp Quarter San Diego [](https://www.expedia.co.uk/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information) Downtown San Diego 8.0/10 Very good (160 reviews) "Smelly building and elevator. Great location but super loud well into the night " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) alvaro [](https://www.expedia.co.uk/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information) ![Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6ef835b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/1b9a69bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/333bf268.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/aa1995cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City24 Hotel Little Italy Mission Hills [](https://www.expedia.co.uk/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) Middletown 9.6/10 Exceptional (116 reviews) "would definitely go back and stay there again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kounwick £136 includes taxes & fees 23 Feb - 24 Feb [](https://www.expedia.co.uk/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/aa0ca94d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 1 Queen Bed with Sofa bed, Bay View | Living area | 40-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/c58a022b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms, Bay View (QueenBed) | Balcony view](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/f6cadddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/96085407.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kasa Little Italy San Diego [](https://www.expedia.co.uk/San-Diego-Hotels-Kasa-Little-Italy-San-Diego.h108772597.Hotel-Information) Downtown San Diego 9.6/10 Exceptional (371 reviews) "My wife and I enjoyed our stay, the room was nice and very clean and this is a great location. The room is a few blocks from Little Italy and the Trolley's. We would stay here again if we travel to San Diego." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £231 includes taxes & fees 12 Feb - 13 Feb [](https://www.expedia.co.uk/San-Diego-Hotels-Kasa-Little-Italy-San-Diego.h108772597.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-23&endDate=2026-02-24®ionId=8484&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-05-10&d1=2026-05-10&endDate=2026-05-13&d2=2026-05-13&lodging=APART_HOTEL) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-05-10&d1=2026-05-10&endDate=2026-05-13&d2=2026-05-13&lodging=APARTMENT) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-05-10&d1=2026-05-10&endDate=2026-05-13&d2=2026-05-13&lodging=VACATION_HOME) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-05-10&d1=2026-05-10&endDate=2026-05-13&d2=2026-05-13&lodging=VILLA) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-05-10&d1=2026-05-10&endDate=2026-05-13&d2=2026-05-13&lodging=CONDO) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-05-10&d1=2026-05-10&endDate=2026-05-13&d2=2026-05-13&lodging=COTTAGE) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+California%2C+United+States+of+America®ionId=8484&latLong=32.76783%2C-117.023086&adults=2&startDate=2026-05-10&d1=2026-05-10&endDate=2026-05-13&d2=2026-05-13&lodging=HOUSE_BOAT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Apart-Hotels.d8484-aaApartHotels.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Apart-Hotels.d8484-aaApartHotels.Travel-Guide-Accommodation) ## Top La Mesa Hotel Reviews ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Clean rooms, but small. Good pools and amenities. Had to pay additional parking and resort fee. " [](https://expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Kings Inn San Diego](https://images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "All" [](https://expedia.co.uk/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "The desk staff were fantastic. Check in was quick and easy. The rooms were neat and clean. No issues at all...as advertised." [](https://expedia.co.uk/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "The staff was very nice. And the room was very clean. And the beds were actually comfortable. " [](https://expedia.co.uk/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](https://images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "Room was really clean. Friendly staff." [](https://expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ![The Sofia Hotel](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg) ### The Sofia Hotel 10/10 Excellent "Room was amazing and temp set very comfortably at check in. Staff was very accommodating and knowledgeable. Happy 100!" [](https://expedia.co.uk/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Beautiful views, outstanding location, clean room, and comfy beds" [](https://expedia.co.uk/San-Diego-Hotels-Sheraton-San-Diego-Resort.h11109.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "Stunning hotel, I could have stayed there all day looking at every little design detail. " [](https://expedia.co.uk/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![Hampton Inn & Suites by Hilton San Diego SeaWorld](https://images.trvl-media.com/lodging/13000000/12970000/12963400/12963301/cc52443d_y.jpg) ### Hampton Inn & Suites by Hilton San Diego SeaWorld 10/10 Excellent "AMAZING! " [](https://expedia.co.uk/San-Diego-Hotels-Hampton-Inn-Suites-San-Diego-Point-Loma.h12963301.Hotel-Information) ## Find out more about La Mesa ## La Mesa Serviced Apartments information | Number of reviews | 1,593 | | ----------------- | ---------------------- | | Accommodation | 39 Serviced Apartments | | Lowest Price | £83 | | Highest Price | £231 | ## Frequently asked questions ### What can I look forward to during my La Mesa aparthotel stay? ### What are visitors' favourite aparthotels for my stay in La Mesa? ### How many aparthotels will I find in La Mesa? ### What should I see in La Mesa? ### What is an aparthotel? ## Explore a world of travel with Expedia - More ways to book - [Book Serviced Apartments in La Mesa on Expedia.com ](https://www.expedia.com/La-Mesa-Apart-Hotels.d8484-aaApartHotels.Travel-Guide-Accommodation)