Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Property class: 3

Choose dates to view prices

A free breakfast buffet, a poolside bar and a free food/drink shopping service are just a few of the amenities provided at Residence Inn By Marriott Jacksonville - Mayo Clinic Area. Stay connected with free in-room WiFi, and guests can find other amenities, such as a garden and dry cleaning/laundry services.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Pet-friendly
  • Free Wi-Fi
  • Air-conditioning
The current price is £117
includes taxes & fees
20 Nov - 21 Nov

Room options

Available filters for rooms
Showing 10 of 10 rooms

View all photos for Studio, 1 King Bed with Sofa bed, Corner

A modern hotel room with a bed, desk, chair, TV, and large windows with curtains.

Studio, 1 King Bed with Sofa bed, Corner

9.8 out of 10
Exceptional
(6 reviews)
  • 533 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom, Corner

A modern kitchen with wooden cabinets, a dishwasher, and a countertop with kitchenware. There is a dining area with a table and chairs, and a living room with a sofa and a TV on the wall.

Studio Suite, 1 Bedroom, Corner

10.0 out of 10
Exceptional
(4 reviews)
  • 646 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed

A modern kitchen with wooden cabinets, a built-in microwave, and a dishwasher.

Studio Suite, 1 King Bed with Sofa bed

9.6 out of 10
Exceptional
(108 reviews)
  • 407 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom

A modern hotel room with a grey sofa, a small round table, a desk with a chair, and a flat-screen TV mounted on the wall.

Studio Suite, 1 Bedroom

9.8 out of 10
Exceptional
(26 reviews)
  • 560 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

A hotel room with a large bed, two bedside tables, and a nightstand with a phone.

Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

9.2 out of 10
Wonderful
(9 reviews)
  • 409 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed (Hearing Accessible)

A hotel room with a large bed, two bedside tables, and a nightstand with a phone.

Studio Suite, 1 King Bed with Sofa bed (Hearing Accessible)

9.0 out of 10
Wonderful
(2 reviews)
  • 391 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Roll-In Shower)

A hotel room with a large bed, two bedside tables, and a nightstand with a phone.

Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Roll-In Shower)

10.0 out of 10
Exceptional
(1 review)
  • 391 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom (Hearing Accessible)

A modern hotel room with a sofa, desk, and kitchenette.

Studio Suite, 1 Bedroom (Hearing Accessible)

8.0 out of 10
Very good
(1 review)
  • 569 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed, Corner (Hearing Accessible)

A modern hotel room with a bed, desk, chair, TV, and large windows with curtains.

Studio, 1 King Bed with Sofa bed, Corner (Hearing Accessible)

9.0 out of 10
Wonderful
(2 reviews)
  • 538 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio Suite, 1 Bedroom, Corner (Mobility/Hearing Access, Roll-In Shwr)

A modern hotel room with a sofa, desk, and kitchenette.

Studio Suite, 1 Bedroom, Corner (Mobility/Hearing Access, Roll-In Shwr)

  • 641 sq ft
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

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About the area

Isle of Palms, a neighbourhood in Jacksonville, is home to Residence Inn By Marriott Jacksonville - Mayo Clinic Area. San Jose Episcopal Church and Fort Caroline National Memorial are local landmarks, and some of the area's activities can be experienced at TPC Sawgrass and Windsor Parke Golf Club. Ready for a night out? Consider Lynch's Irish Pub and Hodges Stadium. Visit our Jacksonville travel guide
Map
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL, 32224

What's nearby

  • A Louis Vuitton store, palm trees, and a Nordstrom store in a shopping area.
    St. Johns Town Center
    8 min drive - 7.9 miles
  • A tall red and white lighthouse with a green top, surrounded by palm trees and a cloudy sky.
    Mayport Naval Station
    21 min drive - 11.6 miles
  • A stadium with a large water body in front, reflecting the structure.
    EverBank Stadium
    21 min drive - 18.8 miles
  • A military jet on a tarmac with a clear sky in the background.
    Jacksonville Naval Air Station
    29 min drive - 30.3 miles
  • A bustling street with historic buildings, a sign for 'The Nature's Legacy' shop, and a plaque for 'Oliver's House'.
    St. George Street
    42 min drive - 41.0 miles

Getting around

  • Jacksonville, FL (CRG-Jacksonville Executive at Craig)
    17 min drive

Restaurants

  • Culver’s
    4 min drive
  • Circle K
    9 min walk
  • Starbucks
    4 min drive
  • Southern Grounds
    3 min drive
  • Al's Pizza
    5 min drive

About this property

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

  • Hotel near St. Johns Town Center
  • A free breakfast buffet, a poolside bar and a free food/drink shopping service are just a few of the amenities provided at Residence Inn By Marriott Jacksonville - Mayo Clinic Area. In addition to a garden and dry cleaning/laundry services, guests can connect to free in-room WiFi.
  • Additional perks include:
    • An outdoor pool, along with sunloungers
    • Free self-parking
    • Express check-out, coffee/tea in reception and a front desk safe
    • 2 meeting rooms, a lift and concierge services
    • Guest reviews say great things about the helpful staff
  • Room features
  • All 155 rooms boast comforts, such as laptop-compatible safes and laptop-friendly workspaces, in addition to perks, such as air conditioning and separate sitting areas. Guest reviews speak positively of the cleanliness rooms at the property.
  • Other conveniences in all rooms include:
    • Bathrooms with baths or showers and free toiletries
    • 55-inch Smart TVs with Netflix, streaming services and premium channels
    • Separate sitting areas, separate dining areas and recycling

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Frequently asked questions

Does Residence Inn By Marriott Jacksonville - Mayo Clinic Area have a pool?

Yes, this property has an outdoor pool.

How much does it cost to stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

As of 15 Nov 2026, prices found for a 1-night stay for 2 adults at Residence Inn By Marriott Jacksonville - Mayo Clinic Area on 20 Nov 2026 start from £117, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Residence Inn By Marriott Jacksonville - Mayo Clinic Area pet-friendly?

Yes, this property allows cats and dogs (limit 2 total) with a maximum weight of up to 18 kg per pet. There's a fee of USD 150 per accommodation, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.

How much is parking at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

Self-parking is free at this property.

What time is check-in at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

Check-in start time: 4:00 PM; check-in end time: 6:00 AM. Late check-in is available during limited hours.

What time is check-out at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

Checkout is at 11:00 AM.

Where is Residence Inn By Marriott Jacksonville - Mayo Clinic Area located?

Located in Isle of Palms, this hotel is within 1 mi (2 km) of Atlantic Intracoastal Waterway and Mayo Clinic Florida. Windsor Parke Golf Club is 2.3 mi (3.6 km) away.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on selected room rates because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Residence Inn By Marriott Jacksonville - Mayo Clinic Area Reviews

9.4

Exceptional

9.6

Cleanliness

9.2

Amenities

9.6

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 503 out of 624 reviews
Rating 8 - Good. 82 out of 624 reviews
Rating 6 - Okay. 15 out of 624 reviews
Rating 4 - Poor. 15 out of 624 reviews
Rating 2 - Terrible. 9 out of 624 reviews

Reviews

Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was amazing 🤩
Stayed 1 night in Nov 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Had a great experience while here. Rooms were clean and spacious. Will definitely stay here again.
Stayed 2 nights in Oct 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Our stay was short, but we truly enjoyed it, clean and breakfast was great!
Stayed 1 night in Aug 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
My Family and I enjoy the Hotel, personal,
Stayed 1 night in Sep 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very convenient to Mayo Clinic. Food was good, room was spacious. Will definitely stay on our next visit.
Stayed 1 night in Aug 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff were very friendly and helpful.
Stayed 1 night in Aug 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The room was clean and comfortable, and the front desk staff was very kind and helpful. Thank you for a wonderful stay!
Stayed 1 night in Aug 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
My family stayed here. Clean hotel and great breakfast.
Stayed 1 night in Jun 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel with clean, comfortable rooms and friendly staff. The location was convenient, and the breakfast was delicious. Overall, we had a pleasant stay and would definitely recommend it.
Stayed 1 night in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice hotel, it even has kitchen, refri, desk. Super clean an quiet.
Stayed 1 night in Aug 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Well maintained and the staff extremely professional!!
Stayed 2 nights in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
An amazing property, with very comfortable room and helpful staff. Complimentary breakfast is great!
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean facility. Suite was perfect for our family of 4. Gym was well-equipped.
Stayed 5 nights in Jul 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We stayed in one bedroom unit. The whole unit was super clean, the arrangement was super comfortable. Beds were super soft and I adore white sheets and blankets! The atmosphere was quite. Breakfast was aboundant and nutritious, lots of options.
Stayed 1 night in Aug 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities
Conveniently located, clean rooms, excellent breakfast
Stayed 2 nights in Jan 2026
Verified review

10/10 Excellent

Great stay! Clean room, friendly staff.
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect location for Mayo Clinic appointments.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The bed was comfortable. The kitchen was a lot nicer than I expected. It was wonderful to have a real freezer. I like that the kitchen also had a sink. The kids loved the tv in the bedroom.
Stayed 1 night in Aug 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room, staff were very helpful, room was comfortable
Stayed 2 nights in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The suite room we had was nice with a full kitchen, dining and living area that was separate from the sleeping area. I will definitely recommend this room to anyone needing to stay near the Mayo Clinic.
Stayed 2 nights in May 2026
Verified review

8/10 Good

Liked: Cleanliness, staff & service, property conditions & facilities
Good location to multiple attractions in the city. Love the free and easily accessible parking.
Stayed 2 nights in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, property conditions & facilities
Good breakfast
Stayed 4 nights in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Location was very perfect for an appointment at The Mayo Clinic. Staff could not have been nicer.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was ok nothing special but the staff were all helpful and upbeat. Would highly recommend this property especially if you’re going to Mayo Clinic.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the size of the rooms, the kitchen, the amazing breakfast and the helpful staff. Only complaint would be to have more towels available.
Stayed 1 night in Mar 2026