Title: All Hotels by Four Seasons in Historic Route 66 - 2025 Updated Prices | Expedia.co.uk [Historic Route 66 Travel Guide](https://expedia.co.uk/Historic-Route-66.dx702654640613646336)[Hotels in Historic Route 66](https://expedia.co.uk/Historic-Route-66-Hotels.d702654640613646336.Travel-Guide-Hotels)[Holiday Rentals in Historic Route 66](https://expedia.co.uk/Historic-Route-66-Holiday-Rentals.d702654640613646336.Travel-Guide-HolidayRentals)[Flights to Historic Route 66](https://expedia.co.uk/Cheap-Flights-To-Historic-Route-66.d702654640613646336.Travel-Guide-Flights)[Historic Route 66 Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Historic-Route-66.d702654640613646336.Car-Hire-Guide)[Historic Route 66 Holidays](https://expedia.co.uk/Historic-Route-66.d702654640613646336.Holidays-City-Breaks) ![North Central Arizona which includes signage](https://images.trvl-media.com/place/1218/93b64b3e-64f1-4166-b6ae-c4c686f3ea8b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels by Four Seasons in Historic Route 66 from £377 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [21 Nov - 22 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2025-11-21&endDate=2025-11-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [22 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2025-11-22&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=702654640613646336&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Historic Route 66 Four Seasons Hotels ![Reception](https://images.trvl-media.com/lodging/1000000/30000/25800/25748/7da48e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/30000/25800/25748/ee956af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/25800/25748/fc796025.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/30000/25800/25748/d00895ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel Chicago Downtown Chicago 9.4/10 Exceptional (1001) "Amazing hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £377 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Chicago-Hotels-Four-Seasons-Hotel-Chicago.h25748.Hotel-Information) ![Rooftop bar](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/89e020ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/941b0ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/e177092f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/641d7f21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel St Louis Downtown St. Louis 9.4/10 Exceptional (1001) "The staff was amazing. The bed was so comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary £380 includes taxes & fees 28 Nov - 29 Nov [](https://www.expedia.co.uk/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/eb9982cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/06dccf6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/7f6e9855.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds, Non Smoking | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/753685a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Resort Rancho Encantado Santa Fe Santa Fe 9.4/10 Exceptional (265) "Food options were good, but limited. The scenery was breathtaking as well as the nearby Santa Fe and the tours we took to the Indian reservation and Los Alamos" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ILAN £538 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Santa-Fe-Hotels-Four-Seasons-Resort-Rancho-Encantado-Santa-Fe.h40731.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-05&endDate=2025-12-06®ionId=702654640613646336&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FHistoric-Route-66-Hotels-Four-Seasons.0-0-d702654640613646336--bFourSeasons.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FHistoric-Route-66-Hotels-Four-Seasons.0-0-d702654640613646336--bFourSeasons.Travel-Guide-Filter-Hotels) ## Top Historic Route 66 Hotel Reviews ![River Hotel](https://images.trvl-media.com/lodging/3000000/2680000/2675400/2675313/9a897fc5_y.jpg) ### River Hotel 10/10 Excellent "Great location. Great price. Staff was exceptional. Room was good sized and clean." [](https://expedia.co.uk/Chicago-Hotels-River-Hotel.h2675313.Hotel-Information) ![Hilton Chicago/Magnificent Mile Suites](https://images.trvl-media.com/lodging/1000000/20000/18600/18514/f21f6764_y.jpg) ### Hilton Chicago/Magnificent Mile Suites 10/10 Excellent "Friendly staff, clean rooms" [](https://expedia.co.uk/Chicago-Hotels-Hilton-ChicagoMagnificent-Mile-Suites.h18514.Hotel-Information) ![Congress Plaza Hotel](https://images.trvl-media.com/lodging/1000000/10000/6500/6452/a9ee91b7_y.jpg) ### Congress Plaza Hotel 10/10 Excellent "Great hotel. Loved the family suite for our family of four. " [](https://expedia.co.uk/Chicago-Hotels-Congress-Plaza-Hotel.h6452.Hotel-Information) ![The Wade](https://images.trvl-media.com/lodging/1000000/10000/1400/1346/f26e0a61_y.jpg) ### The Wade 10/10 Excellent "V" [](https://expedia.co.uk/Chicago-Hotels-W-Chicago-Lakeshore.h1346.Hotel-Information) ![LondonHouse Chicago, Curio Collection by Hilton](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786616/74c2f40d_y.jpg) ### LondonHouse Chicago, Curio Collection by Hilton 10/10 Excellent "Beautiful spacious room, very convenient spot" [](https://expedia.co.uk/Chicago-Hotels-LondonHouse-Chicago.h12786616.Hotel-Information) ![The Whitehall Hotel, BW Premier Collection](https://images.trvl-media.com/lodging/1000000/20000/18000/17903/daaf5f2e_y.jpg) ### The Whitehall Hotel, BW Premier Collection 10/10 Excellent "Awesome stay" [](https://expedia.co.uk/Chicago-Hotels-The-Whitehall-Hotel.h17903.Hotel-Information) ![The Royal Sonesta Chicago Downtown](https://images.trvl-media.com/lodging/1000000/20000/17600/17543/696a55e6_y.jpg) ### The Royal Sonesta Chicago Downtown 10/10 Excellent "The view from my room was absolutely amazing. This is one of the very few hotels whose view looks directly DOWN the river. Not at the river like legitimately looks down the river when you look straight out of your hotel room. It’s amazing. The rooms are a bit dated but the price was right for what we paid. There’s no pool which was disappointing but the location is 10/10. Parking is kinda expensive but honestly just having a car in Chicago is expensive in general. Their parking valet service worked well and they always had my car ready within about 15 min. " [](https://expedia.co.uk/Chicago-Hotels-Royal-Sonesta-Chicago-Downtown.h17543.Hotel-Information) ![Eurostars Magnificent Mile](https://images.trvl-media.com/lodging/2000000/1890000/1880400/1880320/08bbf982_y.jpg) ### Eurostars Magnificent Mile 10/10 Excellent "Loved the room! Clean, cozy, beautiful view!" [](https://expedia.co.uk/Chicago-Hotels-Eurostars-Magnificent-Mile.h1880320.Hotel-Information) ![Hilton Chicago](https://images.trvl-media.com/lodging/1000000/20000/12600/12570/274f52b9_y.jpg) ### Hilton Chicago 10/10 Excellent "Good location, easily walkable " [](https://expedia.co.uk/Chicago-Hotels-Hilton-Chicago.h12570.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Hotels near Lake Michigan](https://www.expedia.co.uk/Lake-Michigan-Hotels.0-l6338716-0.Travel-Guide-Filter-Hotels) - [Cottages in Ohio River Valley](https://www.expedia.co.uk/Ohio-River-Valley-Cottages.d6233674-aaCottages.Travel-Guide-Accommodation) - [Casino Hotels in Ohio River Valley](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Casino-Hotel.0-0-d6233674-tCasinoHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Ohio River Valley](https://www.expedia.co.uk/Ohio-River-Valley-Hotels-Gay-Friendly-Hotel.0-0-d6233674-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - 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