A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Search Business Hotels in Florida Keys

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys Business Hotels

Tonight
5 Sept - 6 Sept
Tomorrow
6 Sept - 7 Sept
Next weekend
11 Sept - 13 Sept
In two weeks
18 Sept - 20 Sept

Our top choices for Florida Keys business-friendly hotels

Pool
Food and drink
Poolside bar
Lobby

1. Havana Cabana at Key West

Havana Cabana at Key West
New Town
United States
Silvia
£128
includes taxes & fees
21 Sept - 22 Sept
Havana Cabana at Key West
Pool
Room, 2 Queen Beds, Ocean View | Living area
Bar (on property)
Reception

2. Hampton Inn Key West FL

Hampton Inn Key West FL
Key West
United States
Melisa
£115
includes taxes & fees
20 Sept - 21 Sept
Hampton Inn Key West FL
Exterior
Exterior
Restaurant
Room

3. Hilton Key West Resort & Marina

Hilton Key West Resort & Marina
Stock Island
United States
Linda
£139
includes taxes & fees
20 Sept - 21 Sept
Hilton Key West Resort & Marina
Hibiscus Waterfront 2-Bedroom, Two Bath Master Suite (Brand New) | Terrace/patio
View from property
Room
Room | Private kitchen

4. Lime Tree Bay Resort

Lime Tree Bay Resort
Long Key
United States
Chadwick
£127
includes taxes & fees
24 Sept - 25 Sept
Lime Tree Bay Resort
Ocean View 3BR Condo with Rooftop Balcony | Balcony
Ocean Front 3BR Presidential Suite | Private kitchen
Beach
Lobby sitting area

5. Beachside Resort & Residences

Beachside Resort & Residences
Key West
United States
Jerome
£151
includes taxes & fees
10 Sept - 11 Sept
Beachside Resort & Residences
Pool
Exterior detail
Front of property – evening/night
View from property

6. Parrot Key Hotel & Villas

Parrot Key Hotel & Villas
Northside Resort
United States
Anthony
£152
includes taxes & fees
14 Sept - 15 Sept
Parrot Key Hotel & Villas
Pool
Exterior
Room
Suite, 1 Bedroom Island View

7. Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
Key West Historic District
United States
Brian
£241
includes taxes & fees
28 Sept - 29 Sept
Ocean Key Resort - A Noble House Resort
Pool
Terrace/patio
Lobby
Exterior

8. DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West
Key West
United States
Jose
£116
includes taxes & fees
15 Sept - 16 Sept
DoubleTree Resort by Hilton Grand Key - Key West
Pool
Bar (on property)
Sports facility
Bar (on property)

9. Hilton Garden Inn Key West / The Keys Collection

Hilton Garden Inn Key West / The Keys Collection
New Town
United States
Amanda
£115
includes taxes & fees
14 Sept - 15 Sept
Hilton Garden Inn Key West / The Keys Collection
Spa
View from property
Beach
Beach

10. Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
Old Town Key West
United States
Deaenna
£175
includes taxes & fees
14 Sept - 15 Sept
Southernmost Beach Resort and Guesthouses
View all properties

Top Florida Keys Hotel Reviews

The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"-"
Julie 1-night trip
Posted less than an hour ago
The Pelican Key Largo Cottages
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"The young girl at the front desk was extremely nice and helpful. As helping me with dinner"
John 1-night trip
Posted less than an hour ago
Waterside Suites & Marina
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Convenience, friendly,just a great time!! ☺️"
kateena 2-night trip
Posted less than an hour ago
Bayside Inn Key Largo
Islander Resort

Islander Resort

10/10 Excellent
"loved it and we will be back"
Lori 2-night trip
Posted 3 hours ago
Islander Resort
Cheeca Lodge & Spa

Cheeca Lodge & Spa

10/10 Excellent
"Lo mejor fue el confort de la habitación, lo recomiendo 100%"
Juan 3-night trip
Posted 16 hours ago
Cheeca Lodge & Spa
Reefhouse Resort & Marina

Reefhouse Resort & Marina

8/10 Good
"We enjoyed our stay here, were upgraded to a partial view room, and noticed to have been among the only people in the pool or dining area when we took did these activities. The staff was attentive, but seemed bothered by the lack of business that they were having, and we felt like a bit of an afterthought at times despite enjoying the resort being “to ourselves”."
Brian 1-night trip
Posted 18 hours ago
Reefhouse Resort & Marina
Fairfield Inn & Suites by Marriott Marathon Florida Keys

Fairfield Inn & Suites by Marriott Marathon Florida Keys

8/10 Good
"Pool area was really nice, breakfast was ok but not much variety. Room was good, had everything you needed"
Lucy 1-night trip
Posted 2 days ago
Fairfield Inn & Suites by Marriott Marathon Florida Keys
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Perfection!"
Lauren 3-night trip
Posted 4 days ago
Playa Largo Resort & Spa, Autograph Collection

Frequently asked questions

How much do business hotels in Florida Keys cost?
Prices for business hotels in Florida Keys range between £115 and £241 per night. Whatever your budget, Expedia can help you find the right space to get the work done. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business hotels are there in Florida Keys?
Florida Keys has 87 business hotels to select from. Whether you're meeting with new clients or working remotely, these stays come with the amenities you need to be productive.
Why book your business hotel in Florida Keys with Expedia?
Here at Expedia, it's our job to help you track down an ideal stay at the right price. From upmarket, corporate-friendly retreats to affordable motels loaded with amenities, you'll have your next work trip planned in just a few clicks.
How can I find cheap business hotels in Florida Keys?
Click on the "business friendly" filter, listed under the "traveller experience" heading, to find cheap business hotels in Florida Keys. Then narrow your search by your preferred hotel star rating and budget. Staying outside the city centre is another way to save.

Explore a world of travel with Expedia