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Our top choices for Florida Keys adults-only hotels

Duval House

Duval House
3.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,064 reviews)
"The staff was excellent and location was perfect"
United States
Melissa
The price is £106
includes taxes & fees
30 Jul - 31 Jul
Duval House

Southernmost House - Adult Exclusive

Southernmost House - Adult Exclusive
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,004 reviews)
"The room was amazing with a great kitchen, and very clean. The staff was very professional and friendly and the breakfast delicious."
United States
Alina
The price is £213
includes taxes & fees
16 Aug - 17 Aug
Southernmost House - Adult Exclusive

Douglas House - Adults Only

Douglas House - Adults Only
3.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (464 reviews)
"Good location"
United States
Christina
The price is £109
includes taxes & fees
27 Jul - 28 Jul
Douglas House - Adults Only

Heron House - Adult Only

Heron House - Adult Only
3.5 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,164 reviews)
"Great stay highly recommended"
United States
Lindsay
The price is £127
includes taxes & fees
28 Jul - 29 Jul
Heron House - Adult Only

The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only
3.0 star property
Old Town Key West
9.0 out of 10, Wonderful, (1,008 reviews)
"Place is awesome!! Will be back super relaxing and close to everything! Also within stumbling distance back from bars haha!"
United States
Christopher
The price is £140
includes taxes & fees
3 Aug - 4 Aug
The Cabana Inn Key West - Adults Only

L'Habitation Guest House - Adults Only

L'Habitation Guest House - Adults Only
2.5 star property
Key West Historic District
9.4 out of 10, Exceptional, (1,002 reviews)
"Loved the location, breakfast and clean room. Staff, Drew, very friendly and helpful. Will definitely stay here again."
United States
Richard
The price is £99
includes taxes & fees
27 Jul - 28 Jul
L'Habitation Guest House - Adults Only

The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only
3.0 star property
Old Town Key West
8.4 out of 10, Very good, (1,423 reviews)
"Overall a great place to stay. Very chill, nice staff, chill pool (appreciate no kids), and great location."
United States
Robert
The price is £137
includes taxes & fees
27 Jul - 28 Jul
The Southernmost Inn - Adults Only

The Grand Guesthouse

The Grand Guesthouse
2.5 star property
Old Town Key West
9.6 out of 10, Exceptional, (1,001 reviews)
"Very quaint. A lot of nice amenities! Would stay there again."
United States
Dan
The price is £116
includes taxes & fees
26 Jul - 27 Jul
The Grand Guesthouse

NYAH Key West - Adults Only

NYAH Key West - Adults Only
3.0 star property
Key West Historic District
8.2 out of 10, Very good, (1,002 reviews)
"Great spot, would stay again"
United States
Ben
The price is £117
includes taxes & fees
27 Jul - 28 Jul
NYAH Key West - Adults Only

Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
2.5 star property
Rock Harbor
9.8 out of 10, Exceptional, (334 reviews)
"Very relaxing and low key spot with lots of fun outdoor amenities, staff got us into our room early and were super helpful and friendly. Would stay here again."
United States
Michelle
The price is £165
includes taxes & fees
26 Jul - 27 Jul
Kona Kai Resort and Gallery - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Discover top Florida Keys attractions

The Florida Keys offer a range of unforgettable experiences for discerning travellers. Begin your adventure in Key West, where the vibrant Mallory Square comes alive at sunset, showcasing local artists and street performers against a backdrop of stunning ocean views. For families, a visit to the Key West Butterfly and Nature Conservatory is a delightful treat, where you can wander through a tropical paradise filled with thousands of fluttering butterflies. Enjoy snorkelling in the crystal-clear waters of John Pennekamp Coral Reef State Park, the first underwater park in the United States, where vibrant coral reefs and diverse marine life await exploration. For a dose of history, the Ernest Hemingway Home and Museum offers a glimpse into the life of the iconic author, complete with lush gardens and the famous six-toed cats. To unwind, consider staying in the charming town of Islamorada, known for its luxurious waterfront hotels and stunning sunsets. Here, you can indulge in fresh seafood at local restaurants and take leisurely strolls along the beach, ensuring you and your family enjoy a relaxing yet adventurous escape. With attentive guest service and top hotels, the Florida Keys promise a memorable holiday that feels both indulgent and straightforward.

Top Florida Keys Hotel Reviews

Frequently asked questions

How much do adults-only hotels in Florida Keys cost?
Expect the price to change depending on the room size you choose and the star rating of the property. Whether you prefer a lavish escape or one that's more budget friendly, Expedia can help you find a stay that fits your needs.
How can I find cheap adults-only hotels in Florida Keys?
Expedia can help you narrow your search for cheap adults-only hotels in Florida Keys. Simply try out our convenient filter tool to select budget, star rating and amenities to refine your search and book the best stay in a matter of clicks.
From what age can you stay in an adult-only hotel in Florida Keys?
The minimum age requirement for an adult-only hotel may differ. To ensure you or any other guest satisfy the criteria, look up the rules of the particular property in Florida Keys you're interested in. Typically, you have to be 16, 18 or 21. Exchanged your vows and setting off on your honeymoon? Or want to live it up with your mates? Expedia's adult-only resorts and hotels are all about amazing experiences for all types of grown-up visitors.
Are all adult-only resorts all-inclusive in Florida Keys?
If you plan to stay at a hotel or resort where practically everything you need is included in a one-off fee, try our "all-inclusive" filter. This will show you all available adult-only all-inclusive retreats in Florida Keys that typically include drinks, food and the room, a host of on-site activities and daily entertainment. Select the hotel you're thinking about to see exactly what you'll get for the price.
Why book your adults-only hotel in Florida Keys with Expedia?
Offering great prices and a fantastic variety of properties, Expedia makes it easy to find an adults-only hotel in Florida Keys. Splurge on a luxury resort or use our handy search filters to locate a more budget-friendly stay. From the minute you work out your travel dates to when you lock in a place that meets your needs, Expedia has got you covered.
When is the best time to stay at an adult-only all-inclusive resort in Florida Keys?
Almost any time is a good time to stay at an adult-only all-inclusive hotel in Florida Keys, but there are a few things you'll want to consider. Start with the time of the year you'd like to travel. Peak season is exciting and popular, but there's a higher demand for accommodation and flights. Low season tends to be less hectic and easier on the purse strings. Of course, the weather is a very important part in making or breaking a getaway, so do a little research before booking your adult-only hotel or resort.
Can I cancel or change my adult-only resort booking?
Of course. Depending on the type of booking you made and how close you are to check in, you may not be charged a fee. Rules can vary among our adult-only hotels and resorts, so read the fine print in your itinerary or head over to Expedia's Trips portal for more information. If you're hoping to make your getaway to Florida Keys as worry-free as possible, search for adult-only properties that are fully refundable.