Title: TOP Adults Only Resorts & Hotels in Florida Keys for 2025 | Expedia.co.uk [Florida Keys Travel Guide](https://expedia.co.uk/Florida-Keys.dx6023765)[Hotels in Florida Keys](https://expedia.co.uk/Florida-Keys-Hotels.d6023765.Travel-Guide-Hotels)[Holiday Rentals in Florida Keys](https://expedia.co.uk/Florida-Keys-Holiday-Rentals.d6023765.Travel-Guide-HolidayRentals)[Flights to Florida Keys](https://expedia.co.uk/Cheap-Flights-To-Florida-Keys.d6023765.Travel-Guide-Flights)[Things to do in Florida Keys](https://expedia.co.uk/Things-To-Do-In-Florida-Keys.d6023765.Travel-Guide-Activities)[Florida Keys Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Florida-Keys.d6023765.Car-Hire-Guide)[Florida Keys Holidays](https://expedia.co.uk/Florida-Keys.d6023765.Holidays-City-Breaks) ![Higgs Beach showing tropical scenes and a beach as well as a large group of people](https://images.trvl-media.com/place/6246822/f00ad239-b8ad-4f0c-b162-acc6426db1e2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Adults Only Resorts & Hotels in Florida Keys - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Florida Keys Adults Only Resorts & Hotels Tonight [20 Nov - 21 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2025-11-20&endDate=2025-11-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [21 Nov - 22 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2025-11-21&endDate=2025-11-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) This weekend [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Top Florida Keys Adults Only Resorts & Hotels ![Courtyard](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/2b7e8bad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/a8250942.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/34b65216.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/db77bb38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Southernmost Inn - Adults Only Old Town Key West 8.2/10 Very good (1191) "Great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Ellen £146 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Key-West-Hotels-The-Southernmost-Inn-Adults-Only.h4280752.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/910000/900500/900423/d8706fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/910000/900500/900423/d8ea2dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/910000/900500/900423/586198d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (Adults Only) | Private kitchen | Microwave](https://images.trvl-media.com/lodging/1000000/910000/900500/900423/4c7ce9b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Duval House Old Town Key West 9.4/10 Exceptional (1006) "Love it, place was beautiful and staff was very friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £135 includes taxes & fees 25 Nov - 26 Nov [](https://www.expedia.co.uk/Key-West-Hotels-Duval-House.h900423.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/77f11bb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![NYAH Private Balcony Room 6 Single Beds | Balcony view](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/a350e3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/eb10500d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Quadruple Room | Individually decorated, individually furnished, soundproofing](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/070a211a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NYAH Key West - Adults Only Key West Historic District 7.8/10 Good (1006) "Clean great staff and perfect pool!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristy £101 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Key-West-Hotels-NYAH-Key-West-Adults-Only.h7500588.Hotel-Information) ![Mansion Room #201 - Ocean View with private balcony - Adults Only | Terrace/patio](https://images.trvl-media.com/lodging/4000000/3840000/3830600/3830519/9dea706f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3840000/3830600/3830519/d08fe38f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mansion Room #106 - Ocean View w/ Direct Pool Access - Adults Only | 1 bedroom, premium bedding, pillow-top beds, individually furnished](https://images.trvl-media.com/lodging/4000000/3840000/3830600/3830519/4498aa15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/4000000/3840000/3830600/3830519/853cc84c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southernmost House Old Town Key West 9.4/10 Exceptional (1004) "Great place with excellent staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Willie £275 includes taxes & fees 17 Dec - 18 Dec [](https://www.expedia.co.uk/Key-West-Hotels-The-Southernmost-House-Hotel.h3830519.Hotel-Information) ![Signature Apartment, 1 Bedroom, Kitchen, Poolside (Room 17) | Terrace/patio](https://images.trvl-media.com/lodging/20000000/19690000/19681600/19681527/537c4db0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed, Patio, Ground Floor (Room 10) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/20000000/19690000/19681600/19681527/962c59be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/20000000/19690000/19681600/19681527/8b4f5465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/20000000/19690000/19681600/19681527/c77e5b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly Old Town Key West 9.8/10 Exceptional (127) "Great place to stay always clean an the employees are very respectful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles £216 includes taxes & fees 21 Nov - 22 Nov [](https://www.expedia.co.uk/Key-West-Hotels-Alexanders-Gay-And-Lesbian-Guesthouse-Adults-Only.h19681527.Hotel-Information) ![Outdoor pool, open 8:00 AM to 8:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/910000/902100/902014/4d24feec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/910000/902100/902014/002755fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/1000000/910000/902100/902014/b2259b66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/902100/902014/8717bede.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heron House Court - Adult Only Key West Historic District 9.0/10 Wonderful (1006) "The stay was good and made it easier to explore nearby places." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) sandhya £108 includes taxes & fees 27 Nov - 28 Nov [](https://www.expedia.co.uk/Key-West-Hotels-Heron-House-Court-Adult-Only.h902014.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/04396af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/c435c8cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/705cf1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/ee4555f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heron House - Adult Only Old Town Key West 9.0/10 Wonderful (1146) "Excellent place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Johnny £141 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Key-West-Hotels-Heron-House-Adult-Only.h57730.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/98bddc65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/56dfeed7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/cf7f237d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | In-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/7000000/6580000/6576700/6576609/a5da01ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cabana Inn Key West - Adults Only Old Town Key West 8.8/10 Excellent (1006) "Rooms are clean, staff was friendly and pool was refreshing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wendy [](https://www.expedia.co.uk/Key-West-Hotels-The-Cabana-Inn-Key-West-Adults-Only.h6576609.Hotel-Information) ![Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1750000/1749500/1749434/c579b899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1750000/1749500/1749434/73aa79d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1750000/1749500/1749434/3347744a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1750000/1749500/1749434/f17f7f22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Weatherstation Inn Old Town Key West 9.4/10 Exceptional (986) "Nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Victoria £151 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/Key-West-Hotels-Weatherstation-Inn.h1749434.Hotel-Information) ![Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/3d7c7063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/1ae9d542.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/0bfa8d1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini fridge](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/bc9a86c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Almond Tree Inn Hotel - Adults Only Old Town Key West 10/10 Exceptional (1004) "Great place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bettina £228 includes taxes & fees 24 Nov - 25 Nov [](https://www.expedia.co.uk/Key-West-Hotels-Almond-Tree-Inn.h809031.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-04&endDate=2025-12-05®ionId=6023765&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Florida Keys ### Discover top Florida Keys attractions The Florida Keys offer a range of unforgettable experiences for discerning travellers. Begin your adventure in Key West, where the vibrant Mallory Square comes alive at sunset, showcasing local artists and street performers against a backdrop of stunning ocean views. For families, a visit to the Key West Butterfly and Nature Conservatory is a delightful treat, where you can wander through a tropical paradise filled with thousands of fluttering butterflies. Enjoy snorkelling in the crystal-clear waters of John Pennekamp Coral Reef State Park, the first underwater park in the United States, where vibrant coral reefs and diverse marine life await exploration. For a dose of history, the Ernest Hemingway Home and Museum offers a glimpse into the life of the iconic author, complete with lush gardens and the famous six-toed cats. To unwind, consider staying in the charming town of Islamorada, known for its luxurious waterfront hotels and stunning sunsets. Here, you can indulge in fresh seafood at local restaurants and take leisurely strolls along the beach, ensuring you and your family enjoy a relaxing yet adventurous escape. With attentive guest service and top hotels, the Florida Keys promise a memorable holiday that feels both indulgent and straightforward. ## Top Florida Keys Hotel Reviews ![Hawks Cay Resort](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/b1845555_y.jpg) ### Hawks Cay Resort 10/10 Excellent "Enjoyed a few days with the kids gere" [](https://expedia.co.uk/Marathon-Hotels-Hawks-Cay-Resort.h6068.Hotel-Information) ![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723_y.jpg) ### Cheeca Lodge & Spa 10/10 Excellent "Amazing!" [](https://expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Baker's Cay Resort Key Largo, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/bbdba544_y.jpg) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton 10/10 Excellent "Clean room , coconut beach was wonderful, the other beach too. Nice rooms with nice views " [](https://expedia.co.uk/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) ## Frequently asked questions ### How much do adults-only hotels in Florida Keys cost? > Expect the price to change depending on the room size you choose and the star rating of the property. Whether you prefer a lavish escape or one that's more budget friendly, Expedia can help you find a stay that fits your needs. ### How can I find cheap adults-only hotels in Florida Keys? > Expedia can help you narrow your search for cheap adults-only hotels in Florida Keys. Simply try out our convenient filter tool to select budget, star rating and amenities to refine your search and book the best stay in a matter of clicks. ### From what age can you stay in an adult-only hotel in Florida Keys? > The minimum age requirement for an adult-only hotel may differ. To ensure you or any other guest satisfy the criteria, look up the rules of the particular property in Florida Keys you're interested in. Typically, you have to be 16, 18 or 21. Exchanged your vows and setting off on your honeymoon? Or want to live it up with your mates? Expedia's adult-only resorts and hotels are all about amazing experiences for all types of grown-up visitors. ### Are all adult-only resorts all-inclusive in Florida Keys? > If you plan to stay at a hotel or resort where practically everything you need is included in a one-off fee, try our "all-inclusive" filter. This will show you all available adult-only all-inclusive retreats in Florida Keys that typically include drinks, food and the room, a host of on-site activities and daily entertainment. Select the hotel you're thinking about to see exactly what you'll get for the price. ### Why book your adults-only hotel in Florida Keys with Expedia? > Offering great prices and a fantastic variety of properties, Expedia makes it easy to find an adults-only hotel in Florida Keys. Splurge on a luxury resort or use our handy search filters to locate a more budget-friendly stay. From the minute you work out your travel dates to when you lock in a place that meets your needs, Expedia has got you covered. ### When is the best time to stay at an adult-only all-inclusive resort in Florida Keys? > Almost any time is a good time to stay at an adult-only all-inclusive hotel in Florida Keys, but there are a few things you'll want to consider. Start with the time of the year you'd like to travel. Peak season is exciting and popular, but there's a higher demand for accommodation and flights. Low season tends to be less hectic and easier on the purse strings. Of course, the weather is a very important part in making or breaking a getaway, so do a little research before booking your adult-only hotel or resort. ### Can I cancel or change my adult-only resort booking? > Of course. Depending on the type of booking you made and how close you are to check in, you may not be charged a fee. Rules can vary among our adult-only hotels and resorts, so read the fine print in your itinerary or head over to Expedia's [Trips portal](https://www.expedia.co.uk/trips) for more information. If you're hoping to make your getaway to Florida Keys as worry-free as possible, search for adult-only properties that are fully refundable. ## Explore a world of travel with Expedia - Accommodation - Packages - More ways to book - [Hotels near John Pennekamp Coral Reef State Park](https://www.expedia.co.uk/John-Pennekamp-Coral-Reef-State-Park-Hotels.0-l6068611-0.Travel-Guide-Filter-Hotels) - [John Pennekamp Coral Reef State Park](https://www.expedia.co.uk/John-Pennekamp-Coral-Reef-State-Park-United-States-of-America.d6068611.Attraction) - [Book Adults Only Resorts & Hotels in Florida Keys on Expedia.com](https://www.expedia.com/Florida-Keys-Hotels-Adults-Only-Resorts.0-0-d6023765-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)