Florida Keys adults only hotels from £91

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Top Adults only hotels in Florida Keys

 Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
3.5 out of 5
1118 Fleming St, Key West, FL
The price is £126 per night from 17 Aug to 18 Aug
£126
17 Aug - 18 Aug
includes taxes & fees
9.8/10 Exceptional! (106 reviews)
"Front desk staff was simply amazing, breakfast time was most enjoyable since Paula was so great. The room was amazing and clean. I will be back."

Reviewed on 5 Aug 2025

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Duval House
3 out of 5
815 Duval St, Key West, FL
The price is £91 per night from 17 Aug to 18 Aug
£91
17 Aug - 18 Aug
includes taxes & fees
9.4/10 Exceptional! (1,001 reviews)
"Super convenient, I did not feel overcrowded by the other visitors. Easy to navigate through."

Reviewed on 7 Aug 2025

Duval House
Southernmost House
4 out of 5
1400 Duval Street, Key West, FL
The price is £241 per night from 13 Aug to 14 Aug
£241
13 Aug - 14 Aug
includes taxes & fees
9.2/10 Wonderful! (1,002 reviews)
"The mansion is beautiful very historic. The staff were so nice and welcoming. We really didn't have to leave the grounds for anything, will be back again!"

Reviewed on 9 Aug 2025

Southernmost House
Casa Morada
3.5 out of 5
136 Madeira Road, Islamorada, FL
The price is £200 per night from 13 Aug to 14 Aug
£200
13 Aug - 14 Aug
includes taxes & fees
9.2/10 Wonderful! (405 reviews)
"The marina was clean and convenient."

Reviewed on 3 Aug 2025

Casa Morada
Ridley House - Key West Historic Inns
3.5 out of 5
601 Caroline St, Key West, FL
The price is £213 per night from 19 Aug to 20 Aug
£213
19 Aug - 20 Aug
includes taxes & fees
9.2/10 Wonderful! (806 reviews)
"Nice, historic hotel within great walking distance to many restaurants and shops. Comfy bed, clean room."

Reviewed on 8 Aug 2025

Ridley House - Key West Historic Inns
Paradise Inn Key West - Adults Only
3.5 out of 5
819 Simonton Street, Key West, FL
The price is £131 per night from 13 Aug to 14 Aug
£131
13 Aug - 14 Aug
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
"Quiet and cozy .. staff was great"

Reviewed on 11 Aug 2025

Paradise Inn Key West - Adults Only
Heron House - Adult Only
3.5 out of 5
512 Simonton St, Key West, FL
The price is £118 per night from 13 Aug to 14 Aug
£118
13 Aug - 14 Aug
includes taxes & fees
9/10 Wonderful! (1,134 reviews)
"i like the atmosphere the peaceful serenity unique interior design outside coffee bar by pool bike rentals next to hotel pool right next to units"

Reviewed on 10 Aug 2025

Heron House - Adult Only
Heron House Court - Adult Only
3 out of 5
412 Frances St, Key West, FL
The price is £110 per night from 18 Aug to 19 Aug
£110
18 Aug - 19 Aug
includes taxes & fees
8.8/10 Excellent! (1,003 reviews)
"Was a quint little place that was quiet and close to the water Very friendly and accommodating."

Reviewed on 11 Aug 2025

Heron House Court - Adult Only
The Cabana Inn Key West - Adults Only
3 out of 5
413 Applerouth Lane, Key West, FL
The price is £111 per night from 19 Aug to 20 Aug
£111
19 Aug - 20 Aug
includes taxes & fees
8.8/10 Excellent! (1,002 reviews)
"Great place to stay right off of Duval street. The staff is polite, professional, personable. Plenty of everything!"

Reviewed on 10 Aug 2025

The Cabana Inn Key West - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
The price is £116 per night from 27 Aug to 28 Aug
£116
27 Aug - 28 Aug
includes taxes & fees
8.2/10 Very Good! (1,150 reviews)
"I love the continental breakfast and the cheese and wine happy hour. It makes paying $40 a night for a resort fee less painful. I also liked that they did not charge an incidental fee assuming you’re gonna trash the hotel room. In fact, most hotels I stayed at while in Key West. Don’t collect both. ..."

Reviewed on 10 Aug 2025

The Southernmost Inn - Adults Only
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently Asked Questions

How can I find the best adults only resorts in Florida Keys?

The best adults only resort for you is deeply personal. First off, decide what you want from your dream holiday, then use our filters to bring it to life. Find resorts with hot tubs, spas and incredible views, then check out the reviews to see how other guests enjoyed their stay.

How much does a Florida Keys adults-only hotel cost?

With Expedia, you can find adults only hotels from £91 to per night. Prices and availability are subject to change. Additional terms may apply.

How can I find an adults only all-inclusive holiday in Florida Keys?

It’s simple. Just select the all-inclusive filter to find the best resorts where you can eat, drink and holiday to your heart’s content.

What can I expect from Florida Keys 5-star all-inclusive adults only hotels?

Luxury comes as standard in the 5-star resorts of Florida Keys. Step into spotless surroundings, stellar service and all the amenities your heart desires, from spas and pools to casinos and cocktail bars.

Why should I book a Florida Keys adults only hotel with entertainment?

When you book an adult only hotel with entertainment, pack your bags to get dolled up for the very best of comedy, cabaret, music, magic and much more – all just steps from your room.

How can I find the best deals on adults only resorts in Florida Keys?

To find amazing deals in Florida Keys and for a quieter experience, book your holiday in . The more flexible you can be with your dates, the better your chances are of getting a fantastic wallet-friendly deal. You can always check out our latest cheap deals for a little inspiration.

Do adults only hotels in Florida Keys offer free cancellation?

Some adults only hotels here offer free cancellation. Some don’t. It’s always best to check before you book. You can filter by free cancellation and pay later options to find resorts with that extra flexibility you want.

Why should I book my adults only resort in Florida Keys with Expedia?

At Expedia, we put everything you need to book your dream trip in one place. With a vast selection of incredible adult only accommodation at your fingertips, all that’s left to do is set your sights on what’s right for you.