Title: TOP Hotels with Air Conditioning in Eastern Panama for 2026 | Expedia.co.uk [Eastern Panama Travel Guide](https://expedia.co.uk/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.co.uk/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Holiday Rentals in Eastern Panama](https://expedia.co.uk/Eastern-Panama-Holiday-Rentals.d6246114.Travel-Guide-HolidayRentals)[Flights to Eastern Panama](https://expedia.co.uk/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Things to do in Eastern Panama](https://expedia.co.uk/Things-To-Do-In-Eastern-Panama.d6246114.Travel-Guide-Activities)[Eastern Panama Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Eastern-Panama.d6246114.Car-Hire-Guide)[Eastern Panama Holidays](https://expedia.co.uk/Eastern-Panama.d6246114.Holidays-City-Breaks) ![50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. #BVSBlue](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Nico Barner # Search Hotels with Air Conditioning in Eastern Panama - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Eastern Panama Hotels with Air Conditioning Tonight [12 Dec - 13 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2025-12-12&endDate=2025-12-13&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2025-12-13&endDate=2025-12-14&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2025-12-12&endDate=2025-12-14&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2025-12-19&endDate=2025-12-21&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Eastern Panama hotels with air conditioning ![Exterior](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/85a94096.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/3eaf0fae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Ocean View | Free WiFi](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/a3494600.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cocotal [](https://www.expedia.co.uk/La-Guaira-Hotels-Hotel-Cocotal.h116789972.Hotel-Information) Isla Grande 10/10 Exceptional (2) "Very rustic place but food is delicious and staff is super friendly and willing to help." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sergio £70 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/La-Guaira-Hotels-Hotel-Cocotal.h116789972.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/5fee50e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, free WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/f2796ab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/d88c1b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/729188af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ranchos de Chalia [](https://www.expedia.co.uk/Puerto-Lindo-Hotels-Ranchos-De-Chalia.h105443903.Hotel-Information) Puerto Lindo 9.8/10 Exceptional (11) "Perfect location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juan £88 includes taxes & fees 17 Dec - 18 Dec [](https://www.expedia.co.uk/Puerto-Lindo-Hotels-Ranchos-De-Chalia.h105443903.Hotel-Information) ![Deluxe Room | In-room safe, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/7979d8c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | View from room](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/90212b31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | In-room safe, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/2321221d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gallery Room, 1 King Bed | In-room safe, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/657647d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ciel y Miel [](https://www.expedia.co.uk/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information) Cacique 10/10 Exceptional (9) "Love this place and would return back numerous times" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean [](https://www.expedia.co.uk/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information) ![On the beach, sun-loungers, beach towels](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/24e34d16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/f2a8388a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/b2caffc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/0eac3661.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caribbean getaway: beach cottage just on the sand [](https://www.expedia.co.uk/Palenque-Hotels-Caribbean-Getaway-Beach-Cottage-Just-On-The-Sand.h71149949.Hotel-Information) Palenque 10/10 Exceptional (1) "The beach view was perfect! I loved hearing the waves all day and throughout the night. My dog and I enjoyed everything and felt very comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth N. £248 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Palenque-Hotels-Caribbean-Getaway-Beach-Cottage-Just-On-The-Sand.h71149949.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/105000000/104140000/104131500/104131479/9162bab0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/105000000/104140000/104131500/104131479/c4fb5930.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104140000/104131500/104131479/a93f8aa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/105000000/104140000/104131500/104131479/ff987ea3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caribbean Paradise - Beachfront Getaway [](https://www.expedia.co.uk/Caribbean-Paradise-Beachfront-Getaway.h104131479.Hotel-Information) Palenque [](https://www.expedia.co.uk/Caribbean-Paradise-Beachfront-Getaway.h104131479.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/1b4156f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/5ebfc967.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/a3e9a150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/7fd698a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cocoloco - Catamaran Lagoon 52F SAN BLAS [](https://www.expedia.co.uk/Nargana-Hotels-Cocoloco-Catamaran-Lagoon-52F-SAN-BLAS.h95807391.Hotel-Information) Narganá £1,576 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Nargana-Hotels-Cocoloco-Catamaran-Lagoon-52F-SAN-BLAS.h95807391.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/b299e0d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Suite, Patio, Garden View | Desk](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/362fd808.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Double Room, Patio, Beach View | Desk](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/5a5332f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL ISLA GRANDE [](https://www.expedia.co.uk/Isla-Grande-Hotels-HOTEL-ISLA-GRANDE.h119947185.Hotel-Information) Isla Grande 5.0/10 (4) "They would not check me in " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carl £76 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Isla-Grande-Hotels-HOTEL-ISLA-GRANDE.h119947185.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/95ace113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/14bad027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/551ebe2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/30f0b989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deluxe Beachfront 4-bedroom house in Colón Province [](https://www.expedia.co.uk/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information) Colón Province £295 includes taxes & fees 19 Dec - 20 Dec [](https://www.expedia.co.uk/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/de84a70a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/fef7062f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/1e44d7b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/9f704818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Despierta sobre el mar [](https://www.expedia.co.uk/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information) Garrote 6.0/10 (1) £83 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information) ![Family Room, 2 Bedrooms, Sea View (Casa Rayo) | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15370000/15362800/15362713/8f40c1a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, 2 Bedrooms, Sea View (Casa Rayo) | Private kitchen | Fridge, electric kettle](https://images.trvl-media.com/lodging/16000000/15370000/15362800/15362713/f6f56668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15370000/15362800/15362713/786f6559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room, Bay View (Casa Rayo) | Bed sheets](https://images.trvl-media.com/lodging/16000000/15370000/15362800/15362713/439b6ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Congo - Rayo Verde - Restaurante [](https://www.expedia.co.uk/Portobelo-Hotels-Casa-Congo-Rayo-Verde-Restaurante.h15362713.Hotel-Information) Portobelo 9.0/10 Wonderful (108) "Great location and staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Oleg £60 includes taxes & fees 20 Dec - 21 Dec [](https://www.expedia.co.uk/Portobelo-Hotels-Casa-Congo-Rayo-Verde-Restaurante.h15362713.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27®ionId=6246114&adults=2&amenities=AIR_CONDITIONING&sort=RECOMMENDED&openPlayBack=true) ## Top Eastern Panama Hotel Reviews