Title: TOP Hotels with Air Conditioning in Eastern Panama for 2026 | Expedia.co.uk [Eastern Panama Travel Guide](https://expedia.co.uk/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.co.uk/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Holiday Rentals in Eastern Panama](https://expedia.co.uk/Eastern-Panama-Holiday-Rentals.d6246114.Travel-Guide-HolidayRentals)[Flights to Eastern Panama](https://expedia.co.uk/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Eastern Panama Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Eastern-Panama.d6246114.Car-Hire-Guide)[Eastern Panama Holidays](https://expedia.co.uk/Eastern-Panama.d6246114.Holidays-City-Breaks) ![50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. #BVSBlue](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Nico Barner ![](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Eastern Panama Hotels with Air Conditioning Tonight [28 Jan - 29 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2026-01-28&endDate=2026-01-29&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [29 Jan - 30 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2026-01-29&endDate=2026-01-30&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2026-01-30&endDate=2026-02-01&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6246114&startDate=2026-02-06&endDate=2026-02-08&adults=2&amenities=AIR_CONDITIONING&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Eastern Panama hotels with air conditioning ![4 outdoor pools](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/272cbe65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gallery Room, 1 King Bed | In-room safe, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/657647d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, free beach shuttle, beach bar](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/dcd510f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room | View from room](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/ada335d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ciel y Miel [](https://www.expedia.co.uk/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information) Cacique 10/10 Exceptional (9 reviews) "Love this place and would return back numerous times" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean [](https://www.expedia.co.uk/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information) ![Basic Room, Bay View | Individually decorated, free WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/fedfb071.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/6f9dc571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![60-inch flat-screen TV with digital channels, streaming services](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/25bdeb78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Room, Bay View | Individually decorated, free WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/588bed17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ranchos de Chalia [](https://www.expedia.co.uk/Puerto-Lindo-Hotels-Ranchos-De-Chalia.h105443903.Hotel-Information) Puerto Lindo 9.8/10 Exceptional (13 reviews) "Perfect location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juan £96 includes taxes & fees 19 Feb - 20 Feb [](https://www.expedia.co.uk/Puerto-Lindo-Hotels-Ranchos-De-Chalia.h105443903.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/85a94096.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, Ocean View | Free WiFi](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/59df013b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, Ocean View | Free WiFi](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/eb642990.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Cocotal [](https://www.expedia.co.uk/La-Guaira-Hotels-Hotel-Cocotal.h116789972.Hotel-Information) Isla Grande 9.4/10 Exceptional (6 reviews) "Beautiful views, great service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Israel £82 includes taxes & fees 3 Feb - 4 Feb [](https://www.expedia.co.uk/La-Guaira-Hotels-Hotel-Cocotal.h116789972.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/ddaf5491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/a9525fbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/5da2e9cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/9dbdc819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caribbean getaway: beach cottage just on the sand [](https://www.expedia.co.uk/Palenque-Hotels-Caribbean-Getaway-Beach-Cottage-Just-On-The-Sand.h71149949.Hotel-Information) Palenque 10/10 Exceptional (1 review) "The beach view was perfect! I loved hearing the waves all day and throughout the night. My dog and I enjoyed everything and felt very comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth N. £238 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Palenque-Hotels-Caribbean-Getaway-Beach-Cottage-Just-On-The-Sand.h71149949.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/7d3884ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/a5df9745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/a3e9a150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/5ebfc967.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cocoloco - Catamaran Lagoon 52F SAN BLAS [](https://www.expedia.co.uk/Nargana-Hotels-Cocoloco-Catamaran-Lagoon-52F-SAN-BLAS.h95807391.Hotel-Information) Narganá £1,506 includes taxes & fees 6 Feb - 7 Feb [](https://www.expedia.co.uk/Nargana-Hotels-Cocoloco-Catamaran-Lagoon-52F-SAN-BLAS.h95807391.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/95ace113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/30f0b989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/66a17c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/14bad027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deluxe Beachfront 4-bedroom house in Colón Province [](https://www.expedia.co.uk/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information) Colón Province £280 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/de84a70a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/a6aae70d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/9f704818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/1e44d7b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Despierta sobre el mar [](https://www.expedia.co.uk/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information) Garrote 6.0/10 (1 review) £81 includes taxes & fees 2 Feb - 3 Feb [](https://www.expedia.co.uk/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/b299e0d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/a3407ec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Suite, Patio, Garden View | Desk](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/15579426.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL ISLA GRANDE [](https://www.expedia.co.uk/Isla-Grande-Hotels-HOTEL-ISLA-GRANDE.h119947185.Hotel-Information) Isla Grande 4.8/10 (5 reviews) "They would not check me in " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carl £83 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/Isla-Grande-Hotels-HOTEL-ISLA-GRANDE.h119947185.Hotel-Information) ![Family Quadruple Room | Laptop workspace, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/cf61e7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/2ca645ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/50019413.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/2a230d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### B&B Lodgings [](https://www.expedia.co.uk/Tocumen-Hotels-BB-Lodgings.h38712982.Hotel-Information) 24 de Diciembre 8.0/10 Very good (76 reviews) "The place is simple and comfortable, well kept, and offers a calm and relaxing atmosphere. The owner is extremely kind, polite, and welcoming, which made the experience even better. Although the location is a bit farther from the city center, it’s a great option if you’re looking for comfort and a peaceful stay. " ![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg) Piettro £37 includes taxes & fees 26 Feb - 27 Feb [](https://www.expedia.co.uk/Tocumen-Hotels-BB-Lodgings.h38712982.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/91000000/90300000/90295300/90295300/984fa3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90300000/90295300/90295300/632df820.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90300000/90295300/90295300/af0b1903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach shuttle](https://images.trvl-media.com/lodging/91000000/90300000/90295300/90295300/dfe1f475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Posada del Buzo [](https://www.expedia.co.uk/Portobelo-Hotels-Hotel-Panama-Dive-Adventure.h90295300.Hotel-Information) Portobelo 9.0/10 Wonderful (10 reviews) "A very sweet and wonderful family runs this hotel with an excellent restaurant and terrific dive center attached. Just a few minutes drive from the center of Portobelo." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael [](https://www.expedia.co.uk/Portobelo-Hotels-Hotel-Panama-Dive-Adventure.h90295300.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-11&endDate=2026-02-12®ionId=6246114&adults=2&amenities=AIR_CONDITIONING&sort=RECOMMENDED&openPlayBack=true) ## Top Eastern Panama Hotel Reviews