TOP Luxury Hotels in Duck Key, FL for 2026 - Duck Key Upscale Hotels

An aerial view of a coastal town with clear blue waters, a marina, and a long pier extending into the sea.

Change your mind
Book hotels with free cancellation
Treat yourself
Save instantly and earn perks with One Key
Learn about One Key
Be picky
Search almost a million properties worldwide

Check availability on Duck Key Luxury Hotels

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Duck Key luxury hotels

A pool area with lounge chairs and umbrellas, surrounded by palm trees.

An aerial view of a coastal resort with multiple white buildings, a clear turquoise sea, and lush greenery.

A pathway leading to a pool area with palm trees and a sunset view.

A modern living room with a balcony overlooking the sea, furnished with a sofa, chairs, and a dining table.

1. Hawks Cay Resort

Marathon

£216

includes taxes & fees

4 Oct - 5 Oct

A resort pool with palm trees and lounge chairs, surrounded by a beachfront.

A resort with a large pool surrounded by lounge chairs, a beach area, and a building with multiple floors.

A modern living room with a sofa, chairs, a dining table, a TV, and a view of the ocean.

An aerial view of a resort island with a large building, a swimming pool, and a boat docked nearby.

2. Villas At Hawks Cay Resort

Marathon

Indulge in oceanfront splendour at this Florida Keys resort with 5 pools, private beach, and full-service spa treatments.

£369

includes taxes & fees

28 Sept - 29 Sept

A wooden deck with a pool and chairs overlooking a beach with palm trees.

A beach with a wooden walkway leading to the water, palm trees, and a clear sky.

A hotel room with a sofa, a desk, a chair, a TV, and a balcony with curtains.

A bar area with stools, a counter, and hanging lanterns.

3. Grassy Flats Resort & Beach Club

Marathon

£185

includes taxes & fees

26 Oct - 27 Oct

An aerial view of a resort with a central pool, multiple buildings, and a beach area with sun loungers.

A bar area with wooden chairs, a bar counter, and a variety of bottles and glasses.

A beach scene with two white chairs, a hammock, and palm trees.

A beach with white chairs and kayaks, palm trees, and a clear view of the ocean.

4. Isla Bella Beach Resort & Spa

Marathon

Indulge in beachfront serenity with 5 outdoor pools, full-service spa, and private balconies overlooking the Florida Keys coast.

£201

includes taxes & fees

28 Sept - 29 Sept

A marina with boats docked, a lighthouse, and a resort with outdoor seating.

A spacious lobby with a central round table, surrounded by wicker chairs, large potted plants, and decorative lanterns.

A bar area with a long counter, multiple bar stools, and a view of the marina with boats and palm trees.

An outdoor dining area with tables and chairs, a pool, and a view of the sea and boats.

5. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Marathon

Oceanfront luxury in Marathon offers private beach, spa services, 4 pools, and spectacular nightly sunsets.

£153

includes taxes & fees

11 Oct - 12 Oct

A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.

An aerial view of a resort with a swimming pool, palm trees, and a dock.

A beach with palm trees, a dock, and lounge chairs.

A hotel room with a bed, a sofa, a coffee table, a desk with a lamp, and a view of the ocean.

6. Amara Cay Resort

Matecumbe

Florida Keys resort offers private beach paradise with upscale rooms, coastal activities, and luxurious relaxation.

£177

includes taxes & fees

4 Oct - 5 Oct

A swimming pool surrounded by palm trees and lounge chairs.

A beach scene with a wooden deck, palm trees, and a gazebo-like structure.

A wooden deck with blue chairs overlooking a beach with palm trees and the ocean.

An aerial view of a resort with a central swimming pool, surrounded by lush greenery and palm trees, with a view of the ocean.

7. Tranquility Bay Beachfront Hotel and Resort

Marathon

Beachfront luxury offers 3 pools, private beach access, and spa treatments blending tranquility with Keys charm.

£204

includes taxes & fees

19 Oct - 20 Oct

View all properties

Top Duck Key Hotel Reviews

Fairfield Inn & Suites by Marriott Marathon Florida Keys

10/10 Excellent

"The property was meticulously clean. The staff was more than helpful if you needed something everyone was very kind. The only thing I object is the parking fee of $20 a day. I don’t see why we should pay $20 a day on their property when we’re staying there other than that, everything was fine. The buffet breakfast was really good. The food was hot and clean. The place was clean and my service dog was safe there if I had to leave them for a little while to do something, I wasn’t worried about it. I’m Social Security. It was very tight. I stayed there many times before I never had a problem."