What is Downtown like?

Travellers to the Downtown neighbourhood in Seneca will be sure to enjoy their stay. Make sure that you visit Oconee County Library Seneca Branch and Blue Ridge Arts Center as part of your Downtown travel plans.

Where is the best place to stay in Downtown?

For your stay in Downtown, Historic Seneca Bungalow is one of the top choices based on our traveller data.

How many hotels will I be able to find in Downtown?

If you're searching for places to stay in Seneca, choose from one of Expedia's 12 hotels and other accommodation options in Downtown.

If I need to cancel my hotel reservation in Downtown, will I receive a refund?

Yes! You'll find that most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals in Downtown.

What can I see and do in this Seneca neighbourhood?

Oconee County Library Seneca Branch, Blue Ridge Arts Center and Seneca Historic District are just a few attractions to check out in Downtown. As you're discovering the neighbourhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Seneca City Hall, Golden Corner Plaza and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, make sure that you visit other sights such as Applewood Shopping Center or Wyndham Plaza.

The Best Hotels in Downtown, Seneca - 2026 Updated Prices

A large lake surrounded by dense forests.

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Our top choices for Downtown hotels

A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

1. Best Western Seneca-Clemson

1 mi from Downtown

Michelle

includes taxes & fees

12 Oct - 13 Oct

A hotel dining area with a long table, multiple chairs, and a bar in the background.

2. Hampton Inn & Suites Seneca-Clemson Area

1.4 mi from Downtown

Lloyd

includes taxes & fees

25 Oct - 26 Oct

A poolside area with outdoor seating and a view of a lake and forested hills.

3. Fairfield Inn & Suites Seneca Clemson Univ Area

1.2 mi from Downtown

Lori

includes taxes & fees

18 Oct - 19 Oct

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

4. Quality Inn Seneca US-123

2.4 mi from Downtown

Julie

includes taxes & fees

18 Oct - 19 Oct

A modern dining area with a high ceiling, large windows, and a buffet setup.

5. Days Inn by Wyndham Seneca / Clemson Area

1.9 mi from Downtown

Rosario

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio area with a fire pit, seating, and string lights.

6. Tru by Hilton Seneca Clemson

5.2 mi from Downtown

Melissa

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

7. Lakeside Lodge Clemson

5.3 mi from Downtown

Lori

includes taxes & fees

12 Oct - 13 Oct

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

4.7 mi from Downtown

Nirumol

includes taxes & fees

21 Oct - 22 Oct

A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

9. Inn @ Clemson

7.2 mi from Downtown

Heather

includes taxes & fees

12 Oct - 13 Oct

A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

10. Days Inn by Wyndham Clemson

7.7 mi from Downtown

David

includes taxes & fees

12 Oct - 13 Oct

A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

11. Holiday Inn Express & Suites Clemson by IHG

7.7 mi from Downtown

John

includes taxes & fees

11 Oct - 12 Oct

A modern kitchen area with a bar counter and seating.

12. Hampton Inn Clemson-University Area

6.1 mi from Downtown

Blaise

includes taxes & fees

30 Oct - 31 Oct

A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

13. Best Western Plus Clemson Hotel & Conference Center

7.3 mi from Downtown

includes taxes & fees

12 Oct - 13 Oct

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

14. The Abernathy of Clemson

6.3 mi from Downtown

Amy

includes taxes & fees

18 Oct - 19 Oct

A golf course with a water body, trees, and a distant view of a bridge.

15. Clemson University's James F. Martin Inn

6.4 mi from Downtown

Lilllian

includes taxes & fees

11 Oct - 12 Oct

A kitchen with a coffee maker, microwave, and refrigerator.

16. Rodeway Inn & Suites Walhalla

8 mi from Downtown

includes taxes & fees

7 Nov - 8 Nov

17. Comfort Inn & Suites Clemson - University Area

7.3 mi from Downtown

Yvette

includes taxes & fees

1 Nov - 2 Nov

A modern bar area with a menu board, bar stools, and a countertop with various items.

18. Courtyard Marriott Clemson

8 mi from Downtown

kim

includes taxes & fees

18 Oct - 19 Oct

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

19. The Shepherd Hotel Downtown Clemson

6.6 mi from Downtown

Laurrie

includes taxes & fees

31 Oct - 1 Nov

A hotel lobby with a reception desk, seating area, and a view of the street outside.

20. Econo Lodge Clemson - University Area

8.1 mi from Downtown

Ruth

includes taxes & fees

15 Oct - 16 Oct

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Where to stay in Downtown

Find the best Downtown areas for the activities you enjoy most.

A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

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A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit South Beach and Lake Keowee.

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Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Oconee County Library Seneca Branch and Keowee Reservoir.

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Keowee Plantation

While Keowee Plantation isn't home to many top sights, Oconee County Library Seneca Branch and Keowee Reservoir are some notable places to visit nearby.

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