Downtown Travel Guide
Seneca
Visit Downtown
Stay near popular Downtown attractions
Top hotels in Downtown
Quality Inn Seneca Clemson Area US-123
226 Hi Tech Rd Seneca SC
The price is £74 per night from 11 Jul to 12 Jul
£74
per night
11 Jul - 12 Jul
Stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in ...
8/10 Very good! (726 reviews)
"Very clean and comfortable for our short stay."
Reviewed on 6 Jul 2026
Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd Clemson SC
The price is £79 per night from 12 Jul to 13 Jul
£79
per night
12 Jul - 13 Jul
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very good! (1,008 reviews)
"Breakfast was wonderful!"
Reviewed on 8 Jul 2026
The Shepherd Hotel Downtown Clemson
110 Sloan St Clemson SC
The price is £116 per night from 13 Jul to 14 Jul
£116
per night
13 Jul - 14 Jul
Stay at this hotel in Clemson. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in their reviews. ...
9.8/10 Exceptional! (836 reviews)
"Absolutely perfect! Beautiful hotel! Excellent staff!"
Reviewed on 7 Jul 2026
Lakeside Lodge Clemson
13500 Clemson Blvd Seneca SC
The price is £101 per night from 5 Aug to 6 Aug
£101
per night
5 Aug - 6 Aug
Stay at this hotel in Seneca. Enjoy free Wi-Fi, free parking and an outdoor pool. Our guests praise the helpful staff and the clean rooms in their reviews. Popular ...
9/10 Wonderful! (1,007 reviews)
"The carpet was moist and smelled like mildew."
Reviewed on 8 Jul 2026
Inn @ Clemson
1303 Tiger Blvd Clemson SC
The price is £61 per night from 9 Jul to 10 Jul
£61
per night
9 Jul - 10 Jul
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in ...
8/10 Very good! (1,003 reviews)
"The hot breakfast was not served because there were fewer than 10 people at the hotel. My opinion is that when a business offers a service, they should keep their promise no matter how many people stay in their property. I paid for the service. Otherwise, the staff was nice."
Reviewed on 7 Jul 2026
Days Inn by Wyndham Anderson
1007 George Smith Mill Rd Anderson SC
The price is £49 per night from 13 Jul to 14 Jul
£49
per night
13 Jul - 14 Jul
Stay at this business-friendly motel in Anderson. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
8/10 Very good! (1,008 reviews)
"We enjoyed the stay and we will be back thank you so much much"
Reviewed on 8 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Downtown
Find the best Downtown areas for the activities you enjoy most.
Serenity Bay
When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.
Pine Ridge Point
If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit South Beach and Lake Keowee.
Indian Oaks
While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Oconee County Library Seneca Branch and Keowee Reservoir.
Keowee Plantation
While Keowee Plantation isn't home to many top sights, Oconee County Library Seneca Branch and Keowee Reservoir are some notable places to visit nearby.
