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South America Accommodation: Most Popular Cities to Stay

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Our top choices for South America business-friendly hotels

Radisson Blu Plaza El Bosque Santiago

Radisson Blu Plaza El Bosque Santiago
4.0 star property
Las Condes
8.8 out of 10, Excellent, (1,001 reviews)
"Good breakfast, clean all around, and excellent staff"
Canada
Hector Eduardo
The price is £106
17 May - 18 May
Radisson Blu Plaza El Bosque Santiago

Grand Hyatt Sao Paulo

Grand Hyatt Sao Paulo
5.0 star property
Itaim Bibi
9.4 out of 10, Exceptional, (1,004 reviews)
"Great place to stay"
United States
Luz Maria
The price is £164
includes taxes & fees
16 May - 17 May
Grand Hyatt Sao Paulo

Pullman Santiago Vitacura

Pullman Santiago Vitacura
5.0 star property
Vitacura
9.0 out of 10, Wonderful, (944 reviews)
"Amazing breakfast"
United States
Beatriz
The price is £73
22 May - 23 May
Pullman Santiago Vitacura

NH Collection Medellín Royal

NH Collection Medellín Royal
5.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,004 reviews)
"Good location Great support staff excellent breakfast and breakfast staff are fantastic"
United States
Vinush
The price is £90
additional charges may apply
30 May - 31 May
NH Collection Medellín Royal

NM Lima Hotel

NM Lima Hotel
4.0 star property
San Isidro
9.2 out of 10, Wonderful, (1,001 reviews)
"Breakfast was fantastic. Staff are amazing and helpful."
United States
Laura
The price is £57
10 May - 11 May
NM Lima Hotel

Pullman Lima San Isidro

Pullman Lima San Isidro
4.0 star property
San Isidro
9.2 out of 10, Wonderful, (832 reviews)
"Excelente "
Mexico
JULIO
The price is £96
9 May - 10 May
Pullman Lima San Isidro

Hotel Plaza El Bosque Ebro

Hotel Plaza El Bosque Ebro
4.0 star property
Las Condes
9.0 out of 10, Wonderful, (1,001 reviews)
"The hotel was close to all the city attractions including the Japanese gardens, we really enjoyed the hospitality and the kindness of the front staff. They helped coordinate shuttle service from the airport and also the breakfast was very appetizing, i enjoyed this hotel!"
United States
Crystal
The price is £95
8 May - 9 May
Hotel Plaza El Bosque Ebro

Hotel Madero Buenos Aires, WorldHotels Elite

Hotel Madero Buenos Aires, WorldHotels Elite
4.5 star property
Puerto Madero
9.2 out of 10, Wonderful, (1,004 reviews)
"Very nice hotel we enjoyed our stay "
United States
Ariel
The price is £142
10 May - 11 May
Hotel Madero Buenos Aires, WorldHotels Elite

Regal Pacific Buenos Aires

Regal Pacific Buenos Aires
4.5 star property
Microcentro
8.8 out of 10, Excellent, (1,004 reviews)
"Really lovely hotel convenient and close to public transport and centre."
United Kingdom
Wendy
The price is £95
9 May - 10 May
Regal Pacific Buenos Aires

GHL Hotel Capital

GHL Hotel Capital
4.0 star property
Fontibon
9.2 out of 10, Wonderful, (1,479 reviews)
"Breakfast diner were great at the Hotel , excelent staff , Clean room , and tv with excellent Chanel’s "
United States
Eduardo
The price is £76
additional charges may apply
30 May - 31 May
GHL Hotel Capital
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South America Hotel Reviews

Frequently asked questions

What are the best business hotels in South America?
That depends on where you're visiting in South America. Many business travellers to Sao Paulo like to base themselves at Hotel Emiliano. This 5-star property comes with a spa and a sauna. Hotel Unique is another great option if you're scheduling a meeting or working remotely in Sao Paulo. Designer toiletries and a swimming pool are some of the handy amenities at this 5-star getaway. When work takes you on the road, you can choose from multiple business hotels in South America that have a total average guest review rating of 9.1.
Why book your business hotel in South America with Expedia?
With handy amenities like conference rooms, laundry facilities and free parking, our business-friendly accommodation come with everything you'll need to settle that big contract — and then chill! Enter your preferred dates and travel destination and we'll help you with the rest.
How can I find cheap business hotels in South America?
Select the "business friendly" filter, located under the "traveller experience" heading, to find cheap business hotels in South America. Then narrow your search by your nightly budget. Staying away from the centre is another way to save.