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South America Accommodation: Most Popular Cities to Stay

A panoramic view of Rio de Janeiro at sunset, featuring the Christ the Redeemer statue, Sugarloaf Mountain, Guanabara Bay, and the cityscape with cable cars.
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Rio de Janeiro

Rio de Janeiro
A village with traditional architecture, surrounded by lush green mountains and a prominent church.
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Bogotá

Bogotá

Check availability on South America Business Hotels

Our top choices for South America business-friendly hotels

View from property

1. Radisson Blu Plaza El Bosque Santiago

Radisson Blu Plaza El Bosque Santiago
4.0 star property
Las Condes
8.8 out of 10, Excellent, (1,000 reviews)
"Clean room and buffet breakfast excellent"
United States
David A
The price is £82
19 Sept - 20 Sept
Radisson Blu Plaza El Bosque Santiago
Reception

2. Grand Hyatt Sao Paulo

Grand Hyatt Sao Paulo
5.0 star property
Itaim Bibi
9.4 out of 10, Exceptional, (1,006 reviews)
"Great place to stay"
United States
Luz Maria
The price is £136
includes taxes & fees
3 Oct - 4 Oct
Grand Hyatt Sao Paulo
Lift

3. Pullman Santiago Vitacura

Pullman Santiago Vitacura
5.0 star property
Vitacura
9.0 out of 10, Wonderful, (997 reviews)
"Hotel location is perfect, lots of places to eat and shop ."
United States
Jose miguel nilo
The price is £81
11 Oct - 12 Oct
Pullman Santiago Vitacura
Outdoor pool, pool umbrellas, pool loungers

4. NH Collection Medellín Royal

NH Collection Medellín Royal
5.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,001 reviews)
"Excellent Location & Services."
United States
Hector
The price is £89
additional charges may apply
20 Sept - 21 Sept
NH Collection Medellín Royal
Breakfast, lunch and dinner served

5. NM Lima Hotel

NM Lima Hotel
4.0 star property
San Isidro
9.2 out of 10, Wonderful, (1,002 reviews)
"Large clean rooms. Suitable amenities and friendly staff."
Australia
Kaveh
The price is £61
18 Oct - 19 Oct
NM Lima Hotel
Outdoor banquet area

6. Pullman Lima San Isidro

Pullman Lima San Isidro
4.0 star property
San Isidro
9.2 out of 10, Wonderful, (845 reviews)
"Great breakfast and staff"
United States
Sophia
The price is £79
3 Oct - 4 Oct
Pullman Lima San Isidro
2 restaurants; breakfast, lunch and dinner served

7. Hotel Plaza El Bosque Ebro

Hotel Plaza El Bosque Ebro
4.0 star property
Las Condes
9.0 out of 10, Wonderful, (1,007 reviews)
"Excellent breakfast and coffee service Staff helpful and ready to serve"
United States
Fernando
The price is £86
20 Sept - 21 Sept
Hotel Plaza El Bosque Ebro
Premium bedding, minibar, in-room safe, desk

8. Hotel Madero Buenos Aires, WorldHotels Elite

Hotel Madero Buenos Aires, WorldHotels Elite
4.5 star property
Puerto Madero
9.2 out of 10, Wonderful, (1,000 reviews)
"All was perfect."
United States
MARIO
The price is £175
27 Sept - 28 Sept
Hotel Madero Buenos Aires, WorldHotels Elite
Exterior

9. Regal Pacific Buenos Aires

Regal Pacific Buenos Aires
4.5 star property
El Centro
8.8 out of 10, Excellent, (1,000 reviews)
"nice breakfast good location"
United States
MARCOS
The price is £99
27 Sept - 28 Sept
Regal Pacific Buenos Aires
Restaurant

10. GHL Hotel Capital

GHL Hotel Capital
4.0 star property
Fontibon
9.2 out of 10, Wonderful, (1,579 reviews)
"The breakfast is awesome ."
Canada
Marlenne
The price is £78
additional charges may apply
17 Oct - 18 Oct
GHL Hotel Capital
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South America Hotel Reviews

Mercure Santiago Centro

Mercure Santiago Centro

8/10 Good
"The room was large and very clean and even had a mini fridge! Staff were super helpful and friendly."
Jaime 2-night trip
Posted 12 hours ago
Mercure Santiago Centro

Frequently asked questions

What are the best business hotels in South America?
That depends on where you're visiting in South America. Many business travellers to Sao Paulo like to base themselves at Hotel Emiliano. This 5-star property comes with a spa and a sauna. Hotel Unique is another great option if you're scheduling a meeting or working remotely in Sao Paulo. Designer toiletries and a swimming pool are some of the handy amenities at this 5-star getaway. When work takes you on the road, you can choose from multiple business hotels in South America that have a total average guest review rating of 9.1.
Why book your business hotel in South America with Expedia?
With handy amenities like conference rooms, laundry facilities and free parking, our business-friendly accommodation come with everything you'll need to settle that big contract — and then chill! Enter your preferred dates and travel destination and we'll help you with the rest.
How can I find cheap business hotels in South America?
Select the "business friendly" filter, located under the "traveller experience" heading, to find cheap business hotels in South America. Then narrow your search by your nightly budget. Staying away from the centre is another way to save.