A city skyline with modern buildings and a waterfront.

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South America Accommodation: Most Popular Cities to Stay

A panoramic view of Rio de Janeiro at sunset, featuring the Christ the Redeemer statue, Sugarloaf Mountain, Guanabara Bay, and the cityscape with cable cars.
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Rio de Janeiro

Rio de Janeiro
A village with traditional architecture, surrounded by lush green mountains and a prominent church.
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Bogotá

Bogotá

Check availability on South America Business Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for South America business-friendly hotels

A modern hotel with a glass facade, surrounded by a park with a skate park and walking paths.

1. Radisson Blu Plaza El Bosque Santiago

Radisson Blu Plaza El Bosque Santiago
4.0 star property
Las Condes
8.8 out of 10, Excellent, (1,002 reviews)
"Todo excelente"
United States
Gonzalo
The price is £92
6 Nov - 7 Nov
Radisson Blu Plaza El Bosque Santiago
A spacious lobby with high ceilings, wooden paneling, and large windows offering views of greenery. Furnished with comfortable seating and a coffee table, the area is well-lit with modern lighting fixtures.

2. Grand Hyatt Sao Paulo

Grand Hyatt Sao Paulo
5.0 star property
Itaim Bibi
9.4 out of 10, Exceptional, (1,008 reviews)
"The building is beautiful and our room was large with separate bedroom and windows on 3 sides. The bathroom was spotless and the rooms very clean and housekeeping made sure it was kept that way. Our housekeepers were very friendly and went out of their way to make sure we were happy! All the staff from check-in, restaurants, the spa, the bellmen and of course our house keepers were polite, helpful and attentive!"
Canada
John
The price is £180
includes taxes & fees
21 Nov - 22 Nov
Grand Hyatt Sao Paulo
An interior space with a modern design, featuring a glass elevator and a geometric ceiling pattern.

3. Pullman Santiago Vitacura

Pullman Santiago Vitacura
5.0 star property
Vitacura
9.0 out of 10, Wonderful, (1,001 reviews)
"Clean room, kind staff at breakfast and well located."
United States
Crystal
The price is £84
20 Nov - 21 Nov
Pullman Santiago Vitacura
A rooftop pool area with lounge chairs and umbrellas, surrounded by lush greenery and modern buildings.

4. NH Collection Medellín Royal

NH Collection Medellín Royal
5.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,002 reviews)
"A wonderful hotel!Clean, comfortable and beautiful. The breakfast was delicious, and the staff was kind and attentive."
United States
Margarita
The price is £85
additional charges may apply
29 Nov - 30 Nov
NH Collection Medellín Royal
A spacious indoor area with patterned flooring, multiple tables and chairs, and a high ceiling with a large canopy.

5. NM Lima Hotel

NM Lima Hotel
4.0 star property
San Isidro
9.2 out of 10, Wonderful, (1,000 reviews)
"Nice staff , great breakfast and very clean , good location."
United States
Magaly
The price is £68
6 Nov - 7 Nov
NM Lima Hotel
A modern hotel lobby with a buffet area, seating arrangements, and a large window providing natural light.

6. Pullman Lima San Isidro

Pullman Lima San Isidro
4.0 star property
San Isidro
9.2 out of 10, Wonderful, (851 reviews)
"Great breakfast and staff"
United States
Sophia
The price is £93
20 Nov - 21 Nov
Pullman Lima San Isidro
An outdoor cafe with tables and chairs, a covered seating area, and a view of the street.

7. Hotel Plaza El Bosque Ebro

Hotel Plaza El Bosque Ebro
4.0 star property
Las Condes
9.0 out of 10, Wonderful, (1,005 reviews)
"Great location , hotel staff so good , the hotel clean and breakfast buffe the best"
United States
mauricio
The price is £91
5 Nov - 6 Nov
Hotel Plaza El Bosque Ebro
A modern bathroom with two sinks, a large mirror, and a view of a city skyline through large windows.

8. Hotel Madero Buenos Aires, WorldHotels Elite

Hotel Madero Buenos Aires, WorldHotels Elite
4.5 star property
Puerto Madero
9.2 out of 10, Wonderful, (1,003 reviews)
"Very good hotel"
United States
Jennifer
The price is £170
3 Dec - 4 Dec
Hotel Madero Buenos Aires, WorldHotels Elite
A poolside area with lounge chairs and towels, surrounded by greenery and a modern building facade.

9. Regal Pacific Buenos Aires

Regal Pacific Buenos Aires
4.5 star property
El Centro
8.8 out of 10, Excellent, (1,003 reviews)
"The hotel was in a great location, the staff was super helpful, the room was very comfortable, and the breakfast was great"
United States
Dana Priscila
The price is £103
6 Nov - 7 Nov
Regal Pacific Buenos Aires
A buffet with various food items and a coffee station.

10. GHL Hotel Capital

GHL Hotel Capital
4.0 star property
Fontibon
9.2 out of 10, Wonderful, (1,616 reviews)
"All about this hotel is amazing"
Canada
Israel
The price is £74
additional charges may apply
14 Nov - 15 Nov
GHL Hotel Capital
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South America Hotel Reviews

Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

10/10 Excellent
"Well place, friendly staff and great environment"
Luis 1-night trip
Posted 1 day ago
Almacruz Hotel y Centro de Convenciones

Frequently asked questions

What are the best business hotels in South America?
That depends on where you're visiting in South America. Many business travellers to Sao Paulo like to base themselves at Hotel Emiliano. This 5-star property comes with a spa and a sauna. Hotel Unique is another great option if you're scheduling a meeting or working remotely in Sao Paulo. Designer toiletries and a swimming pool are some of the handy amenities at this 5-star getaway. When work takes you on the road, you can choose from multiple business hotels in South America that have a total average guest review rating of 9.1.
Why book your business hotel in South America with Expedia?
With handy amenities like conference rooms, laundry facilities and free parking, our business-friendly accommodation come with everything you'll need to settle that big contract — and then chill! Enter your preferred dates and travel destination and we'll help you with the rest.
How can I find cheap business hotels in South America?
Select the "business friendly" filter, located under the "traveller experience" heading, to find cheap business hotels in South America. Then narrow your search by your nightly budget. Staying away from the centre is another way to save.