Title: South America Boutique Hotels, : South America Hotel Guide | Expedia.co.uk [South America Travel Guide](https://expedia.co.uk/South-America.dx6023117)[South America Hotels](https://expedia.co.uk/Destinations-In-South-America.d6023117.Hotel-Destinations)[Holiday Rentals in South America](https://expedia.co.uk/Destinations-In-South-America.d6023117.Holiday-Rental-Destinations)[South America Flights](https://expedia.co.uk/Destinations-In-South-America.d6023117.Flight-Destinations)[South America Car Hire](https://expedia.co.uk/Destinations-In-South-America.d6023117.Car-Hire-Destinations)[South America Holidays](https://expedia.co.uk/South-America.d6023117.Holidays-City-Breaks) ![Cusco featuring a ruin, heritage architecture and a house](https://images.trvl-media.com/place/941/8118e1a4-6ad8-49e0-b1b9-dbc505b8c6d6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Boutique Hotels in South America - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South America Boutique Hotels Tonight [5 Nov - 6 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2025-11-05&endDate=2025-11-06&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [6 Nov - 7 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2025-11-06&endDate=2025-11-07&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2025-11-07&endDate=2025-11-09&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6023117&startDate=2025-11-14&endDate=2025-11-16&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top South America Boutique Hotels ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/2000000/1800000/1795000/1794972/42cccf50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/2000000/1800000/1795000/1794972/d87df7fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1800000/1795000/1794972/1521a835.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1800000/1795000/1794972/2c78686b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mine Hotel Boutique Palermo 9.6/10 Exceptional (1001) "Such a beautiful spot in the heart of Palermo Soho! Whether you on solo or traveling with your partner, I recommend this charming oasis. The staff kind and attentive, with many recommendations. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sophia £130 24 Nov - 25 Nov [](https://www.expedia.co.uk/Buenos-Aires-Hotels-Mine-Hotel-Boutique.h1794972.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3660000/3657500/3657439/8c9c0b71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Room, Jetted Tub | Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/4000000/3660000/3657500/3657439/a3379e55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Room, Jetted Tub | Private spa tub](https://images.trvl-media.com/lodging/4000000/3660000/3657500/3657439/2d157c69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3660000/3657500/3657439/e990435d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aubrey Hotel Boutique Bellavista 9.4/10 Exceptional (132) "Property was closed. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £100 2 Dec - 3 Dec [](https://www.expedia.co.uk/Santiago-Hotels-The-Aubrey-Santiago.h3657439.Hotel-Information) ![Suite, Terrace | Terrace/patio](https://images.trvl-media.com/lodging/4000000/3890000/3883800/3883785/b00c3792.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/4000000/3890000/3883800/3883785/08a8f165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Argentinean cuisine, garden views ](https://images.trvl-media.com/lodging/4000000/3890000/3883800/3883785/fa7014ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3890000/3883800/3883785/ae48f9d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fierro Hotel Buenos Aires Palermo 9.8/10 Exceptional (1006) "Very friendly and helpful staff, good breakfast, spacious room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sophia £176 13 Nov - 14 Nov [](https://www.expedia.co.uk/Buenos-Aires-Hotels-Fierro-Hotel-Buenos-Aires.h3883785.Hotel-Information) ![Bicycling](https://images.trvl-media.com/lodging/3000000/2560000/2553600/2553557/9a92c93f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (USD 8 per person)](https://images.trvl-media.com/lodging/3000000/2560000/2553600/2553557/c63d0c04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/3000000/2560000/2553600/2553557/4786393a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2560000/2553600/2553557/af5c001a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CasaCalma Hotel Retiro 9.6/10 Exceptional (972) "Great place. Great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £83 3 Dec - 4 Dec [](https://www.expedia.co.uk/Buenos-Aires-Hotels-CasaCalma-Hotel.h2553557.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1810000/1808200/1808145/43268e19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1810000/1808200/1808145/d85666f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1810000/1808200/1808145/013a36c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1810000/1808200/1808145/08afcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vain Boutique Hotel Palermo 9.2/10 Wonderful (651) "Great place, staff super friendly. Breakfast was so good with fruit, eggs on ordee cheese and bread" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Heinrich £107 25 Nov - 26 Nov [](https://www.expedia.co.uk/Buenos-Aires-Hotels-Vain-Boutique-Hotel.h1808145.Hotel-Information) ![Indoor pool, outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2650000/2645700/2645670/2ed2aa61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2650000/2645700/2645670/91a110e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/3000000/2650000/2645700/2645670/98206176.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/3000000/2650000/2645700/2645670/238bca89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ananda Hotel Boutique Cartagena Walled City 9.2/10 Wonderful (422) "good staff" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Yuanlong £252 additional charges may apply 7 Nov - 8 Nov [](https://www.expedia.co.uk/Cartagena-Hotels-Ananda-Hotel-Boutique.h2645670.Hotel-Information) ![Junior Suite | Premium bedding, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/6000000/5720000/5714100/5714062/ee86340b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5720000/5714100/5714062/f232d9bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/6000000/5720000/5714100/5714062/d714243c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV, iPod dock](https://images.trvl-media.com/lodging/6000000/5720000/5714100/5714062/fcc61d74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stannum Boutique Hotel & Spa Downtown La Paz 9.4/10 Exceptional (721) "Good breakfast. The room was quiet. Cleaning was done fairly quickly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Iaroslav £79 5 Dec - 6 Dec [](https://www.expedia.co.uk/La-Paz-Hotels-Stannum-Boutique-Hotel-Spa.h5714062.Hotel-Information) ![Indoor spa tub](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803575/99e3e69b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, Turkish bath/hammam, body treatments, hydrotherapy, aromatherapy](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803575/38e0d9f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803575/7cbdffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Azur | Minibar, in-room safe, individually decorated, blackout curtains](https://images.trvl-media.com/lodging/3000000/2810000/2803600/2803575/dc285559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Azur Real Hotel Boutique & Spa Centro 9.4/10 Exceptional (365) "Nice hotel, staff very friendly and nice food. Pay in cash if possible as cheaper than using a card. Good ac system and very tasty granola " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Lucas [](https://www.expedia.co.uk/Cordoba-Hotels-Azur-Real-Hotel-Boutique.h2803575.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/4000000/3440000/3439500/3439490/962f0e6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/4000000/3440000/3439500/3439490/22233126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, pool loungers](https://images.trvl-media.com/lodging/4000000/3440000/3439500/3439490/9b7f02ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/4000000/3440000/3439500/3439490/b204e6c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Duque Hotel Boutique & Spa Palermo 9.4/10 Exceptional (847) "Excellent staff, comfortable room, great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sean £116 4 Dec - 5 Dec [](https://www.expedia.co.uk/Buenos-Aires-Hotels-Duque-Hotel-Boutique-Spa.h3439490.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5450000/5441600/5441563/1c390246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Minibar, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/6000000/5450000/5441600/5441563/4c619204.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/6000000/5450000/5441600/5441563/2b045cdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/6000000/5450000/5441600/5441563/ff9da286.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SU Merced Boutique Hotel Downtown Santiago 9.2/10 Wonderful (224) "Staff was excellent. Breakfast buffet was great. Rooms were comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller [](https://www.expedia.co.uk/Santiago-Hotels-SU-Merced-Boutique-Hotel.h5441563.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-19&endDate=2025-11-20®ionId=6023117&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-America-Boutique-Hotel.0-0-d6023117-tBoutiqueHotel.Hotel-Filter-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-America-Boutique-Hotel.0-0-d6023117-tBoutiqueHotel.Hotel-Filter-Destinations) ## Top South America Hotel Reviews ![Windsor Asturias Hotel](//images.trvl-media.com/lodging/2000000/1780000/1775600/1775573/0ca96436_y.jpg) ### Windsor Asturias Hotel 10/10 Excellent "Staff was friendly and professional. Room was nice and clean. " [](https://expedia.co.uk/Rio-De-Janeiro-Hotels-Windsor-Asturias-Hotel.h1775573.Hotel-Information) ![InterContinental São Paulo by IHG](//images.trvl-media.com/lodging/1000000/200000/198400/198375/242e7b38_y.jpg) ### InterContinental São Paulo by IHG 10/10 Excellent "Our experience was amazing, facility, the hotel, the satff, the location everything was amazingly wonderful, clean, safe, beautiful, great location and staff are amazing. At the reception desk and checkin, Angélio and also Alejandro and Renata at the Intercontinental club, they were amazing " [](https://expedia.co.uk/Sao-Paulo-Hotels-InterContinental-Sao-Paulo.h198375.Hotel-Information) ![NH Buenos Aires Tango](//images.trvl-media.com/lodging/4000000/3310000/3307900/3307803/4c66c3b9_y.jpg) ### NH Buenos Aires Tango 10/10 Excellent "Muy buena atención, muy amables y colaborsdores" [](https://expedia.co.uk/Buenos-Aires-Hotels-NH-Buenos-Aires-Tango.h3307803.Hotel-Information) ![Hilton Buenos Aires](//images.trvl-media.com/lodging/1000000/550000/547000/546934/d51890e8_y.jpg) ### Hilton Buenos Aires 10/10 Excellent "Great area to walk!" [](https://expedia.co.uk/Buenos-Aires-Hotels-Hilton-Buenos-Aires.h546934.Hotel-Information) ![Mercure Santiago Centro](//images.trvl-media.com/lodging/2000000/1550000/1541200/1541172/0a5f7e42_y.jpg) ### Mercure Santiago Centro 10/10 Excellent "Very central location. Most city landmarks at walking distance. Friendly staff." [](https://expedia.co.uk/Santiago-Hotels-Mercure-Santiago-Centro.h1541172.Hotel-Information) ![Lennox Hotel Buenos Aires](//images.trvl-media.com/lodging/5000000/4190000/4182700/4182634/ffb5b7b3_y.jpg) ### Lennox Hotel Buenos Aires 10/10 Excellent "⭐️⭐️⭐️⭐️⭐️ Very convenient hotel, perfectly located in the downtown area! Everything was clean, the service was excellent, and the staff was friendly and helpful. I really enjoyed my stay and would definitely come back." [](https://expedia.co.uk/Buenos-Aires-Hotels-Lennox-Hotel-Buenos-Aires.h4182634.Hotel-Information) ![Libertador Hotel](//images.trvl-media.com/lodging/1000000/10000/9300/9291/d48bbed6_y.jpg) ### Libertador Hotel 10/10 Excellent "Stay was perfect!!" [](https://expedia.co.uk/Buenos-Aires-Hotels-Libertador-Hotel.h9291.Hotel-Information) ![Melia Paulista](//images.trvl-media.com/lodging/2000000/1070000/1062900/1062869/2882d35d_y.jpg) ### Melia Paulista 10/10 Excellent "Staff is amazing, especially Rebecca at the front. Very good location on Paulista. The kids play area was a huge hit with our 2yo son. Highly recommend this hotel for families with young kids, and others." [](https://expedia.co.uk/Sao-Paulo-Hotels-Melia-Paulista.h1062869.Hotel-Information) ![Almacruz Hotel y Centro de Convenciones](//images.trvl-media.com/lodging/1000000/10000/1500/1496/b4c00de4_y.jpg) ### Almacruz Hotel y Centro de Convenciones 10/10 Excellent "It is a beautiful place,excellent services,very pleasant workers and the location was great" [](https://expedia.co.uk/Santiago-Hotels-Almacruz-Hotel-Y-Centro-De-Convenciones.h1496.Hotel-Information)