A coastal landscape with clear turquoise waters, sandy beaches, and volcanic hills.

Find the best Santa Cruz Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Santa Cruz Accommodation: Most Popular Cities to Stay

A woman sitting on a beach facing the ocean with a sea turtle nearby.
HotelsHotels

Puerto Ayora

Puerto Ayora
A tortoise in a lush green forest.
HotelsHotels

Santa Rosa

Santa Rosa

Check prices for these dates

This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Santa Cruz hotels

A swimming pool with a wooden pergola, lounge chairs, and umbrellas.

1. Hotel Fiesta

Hotel Fiesta
3.5 star property
Puerto Ayora
9.0 out of 10, Wonderful, (448 reviews)
"The location of the hotel is ideal for all of the activities you would be exploring on the island. The staff is super friendly and helpful, the hotel has a beautiful charm, and it’s well maintained.."
United States
Dayana Cristina
The price is £119
14 Oct - 15 Oct
Hotel Fiesta
A pool area with lounge chairs and umbrellas, surrounded by cacti and palm trees, overlooking a body of water.

2. Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel
4.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (104 reviews)
"Wonderful staff and great facility!"
United States
Conrad
The price is £421
25 Oct - 26 Oct
Finch Bay Galapagos Hotel
A courtyard with a swimming pool, stone walls, palm trees, and outdoor seating.

3. Maidith Galapagos Inn

Maidith Galapagos Inn
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (167 reviews)
"Really unique place and super friendly staff would definitely stay again."
United Kingdom
Thomas
The price is £88
17 Oct - 18 Oct
Maidith Galapagos Inn
A modern indoor pool area with a hanging chair, a small pool, and a seating area with a view of the pool.

4. Hotel el descanso del Guia

Hotel el descanso del Guia
3.5 star property
Puerto Ayora
8.8 out of 10, Excellent, (234 reviews)
"Clean room Good breakfast Very helpful staff"
United States
marcilene
The price is £52
12 Nov - 13 Nov
Hotel el descanso del Guia
A poolside area with wicker furniture, a bottle of wine, and boats in the background.

5. El Barranco Galapagos

El Barranco Galapagos
2.5 star property
Puerto Ayora
9.8 out of 10, Exceptional, (98 reviews)
"Love this place. Perfect location. Breakfast was delicious"
United States
Gloria
The price is £179
17 Oct - 18 Oct
El Barranco Galapagos
A spacious indoor dining area with a high ceiling, bamboo beams, and hanging wicker lamps. Tables are set with white tablecloths and woven placemats.

6. Royal Palm Galapagos, Curio Collection Hotel by Hilton

Royal Palm Galapagos, Curio Collection Hotel by Hilton
4.5 star property
Santa Rosa
9.4 out of 10, Exceptional, (62 reviews)
"Fabulous! Stephanie the receptionist is amazing!"
United States
DR DAVID GATESBUFFETT
The price is £219
13 Oct - 14 Oct
Royal Palm Galapagos, Curio Collection Hotel by Hilton
A beach with clear turquoise waters and a sandy shoreline.

7. Hotel Ninfa

Hotel Ninfa
3.5 star property
Puerto Ayora
8.6 out of 10, Excellent, (256 reviews)
"Very helpful staff with nice room. Breakfast was good and also a nice jacuzzi by the pool. Close to many bars and restaurants also."
United Kingdom
Andrew
The price is £114
13 Oct - 14 Oct
Hotel Ninfa
A dining table with breakfast items and a view of the sea with boats.

8. Angermeyer Waterfront Inn

Angermeyer Waterfront Inn
3.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (147 reviews)
"We loved our stay and the staff was amazing, so welcoming and thoughtful!"
United States
David
The price is £213
3 Nov - 4 Nov
Angermeyer Waterfront Inn
A buffet setup with various food items and condiments.

9. Hotel Cucuve

Hotel Cucuve
4.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (308 reviews)
"Everything was up to expectations, great stay!"
United States
Sylvia
The price is £151
17 Oct - 18 Oct
Hotel Cucuve
A spacious room with a large window overlooking the sea, wooden flooring, a round rug, a bed, and a seating area.

10. Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (132 reviews)
"Charming hotel right on the water. Seals and crabs in our breakfast view."
United States
Christine
The price is £210
11 Nov - 12 Nov
Blu Galapagos Sustainable Waterfront Lodge
A table with fruit, a drink, and a laptop on a balcony with a view of the sea and boats.

11. Hotel La Casa de Judy

Hotel La Casa de Judy
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (183 reviews)
"This hotel was a great choice. Close enough to walk into town, great views, clean room (including bathroom) and friendly and helpful staff."
Canada
Alexandra
The price is £64
19 Oct - 20 Oct
Hotel La Casa de Judy
A covered outdoor area with a hammock, wooden seating, and potted plants.

12. Galapagos Dreams

Galapagos Dreams
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (150 reviews)
"Very helpful staff. Nice room, good location"
United States
Robert
The price is £65
10 Nov - 11 Nov
Galapagos Dreams
An outdoor dining area with tables and chairs, a covered seating area, and a view of the ocean.

13. Ikala Galapagos Hotel

Ikala Galapagos Hotel
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (158 reviews)
"great stay at Ikala"
United States
Manoussos
The price is £198
12 Nov - 13 Nov
Ikala Galapagos Hotel
A beach with people walking and swimming, boats in the background, and a clear blue sky.

14. Galapagos Verde Azul

Galapagos Verde Azul
3.0 star property
Puerto Ayora
8.6 out of 10, Excellent, (73 reviews)
"Wonderful place to stay!"
Canada
sierra
The price is £60
22 Oct - 23 Oct
Galapagos Verde Azul
A hotel with a swimming pool, outdoor seating, and a well-lit entrance.

15. Acacia Galapagos Boutique Hotel

Acacia Galapagos Boutique Hotel
2.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (44 reviews)
"great place to stay"
United States
Karla Paola Garcia
The price is £165
17 Oct - 18 Oct
Acacia Galapagos Boutique Hotel
A swimming pool with a waterfall feature, surrounded by palm trees and a clear blue sky.

16. Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos
3.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (58 reviews)
"Everything was great!!"
United States
TAKUHIRO
The price is £72
14 Oct - 15 Oct
Fernandina Hotel & Spa Galápagos
A room with a round table, two chairs, a potted plant, and a window with blue shutters.

17. HOTEL CROSSMAN

HOTEL CROSSMAN
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (13 reviews)
"Very friendly staff"
Canada
PENGFEI
The price is £47
14 Oct - 15 Oct
HOTEL CROSSMAN
A courtyard with a tortoise statue, outdoor seating, and a sign with multiple directions.

18. Hotel Coloma Galapagos

Hotel Coloma Galapagos
3.0 star property
Puerto Ayora
9.2 out of 10, Wonderful, (202 reviews)
"We had the best time in Galapagos and one of them was the hotel. The 2 ladies in reception were excellent extremely helpful and so kind. Very safe place, the breakfasts are stunning, we were able to try at least one day bc the other we had a early tours. The location is perfect bc it is at the Main Street. It guides you directly to the malecón with less than the 10 min walk. Overall amazing super clean and perfect for overnight we stay 3 nights and not complain at all."
United States
Marco Antonio Pizarro
The price is £63
16 Oct - 17 Oct
Hotel Coloma Galapagos
A wooden deck with a table and chairs, overlooking a lush green landscape and the ocean.

19. Hotel Deja Vu

Hotel Deja Vu
3.0 star property
Puerto Ayora
7.8 out of 10, Good, (31 reviews)
"The staff was really great. The breakfast was real good. No complaints we would stay there again."
United States
Randy
The price is £71
13 Oct - 14 Oct
Hotel Deja Vu
A pool area with lounge chairs, a hot tub, and a view of the ocean.

20. Hotel Villa Escalesia Galapagos

Hotel Villa Escalesia Galapagos
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (7 reviews)
"Hidden gem of Santa Cruz"
United States
Robert
The price is £220
13 Oct - 14 Oct
Hotel Villa Escalesia Galapagos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Great weekend hotel deals in Santa Cruz

Showing deals for:23 Oct - 25 Oct

Image gallery for Enchanted Galapagos Lodge

Enchanted Galapagos Lodge

3.0 star property
Bella Vista
8.0/10Very good (3 reviews)
10% off
Price is £305
for 2 nights, 1 room
£152 per night
Enchanted Galapagos Lodge

Hotels recommended for families in Santa Cruz

A room with a round table, two chairs, a potted plant, and a window with blue shutters.

HOTEL CROSSMAN

HOTEL CROSSMAN
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (13)
The price is £47
14 Oct - 15 Oct
HOTEL CROSSMAN
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Hotel Coloma Galapagos

Hotel Coloma Galapagos

10/10 Excellent
"We had the best time in Galapagos and one of them was the hotel. The 2 ladies in reception were excellent extremely helpful and so kind. Very safe place, the breakfasts are stunning, we were able to try at least one day bc the other we had a early tours. The location is perfect bc it is at the Main Street. It guides you directly to the malecón with less than the 10 min walk. Overall amazing super clean and perfect for overnight we stay 3 nights and not complain at all."
Marco Antonio Pizarro 3-night trip
Posted 15 hours ago
Hotel Coloma Galapagos