Santa Cruz Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Top destinations in Santa Cruz

A woman sitting on a beach facing the ocean with a sea turtle nearby.

Puerto Ayora

Puerto Ayora

Top Santa Cruz Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Galapagos Native

Galapagos Native

£1,290
per person
24 Nov - 1 Dec
found 1 day ago
Return flight included
London (LON) to Isla Baltra (GPS)
7.8/10 Good! (98 reviews)
Do not book this hotel. There was zero hot water on any of the days, and on our last day there was no water at all. Took over an hour first morning to get our breakfast (eggs and toast) which came out cold. Weak lukewarm instant coffee! Second morning no better, we asked for hot water to use our own Starbucks instant coffee, and again, only lukewarm.

Reviewed on 1 Oct 2026

Galapagos Sea Star

Galapagos Sea Star

£3,897
per person
24 Nov - 1 Dec
found 1 day ago
Return flight included
London (LON) to Isla Baltra (GPS)
No reviews
Hotel Flamingo

Hotel Flamingo

£1,678
per person
24 Nov - 1 Dec
found 1 day ago
Return flight included
London (LON) to Isla Baltra (GPS)
8.8/10 Excellent! (123 reviews)
Excellent location!

Reviewed on 26 Jul 2026

Hotel Albatross

Hotel Albatross

£1,526
per person
24 Nov - 1 Dec
found 1 day ago
Return flight included
London (LON) to Isla Baltra (GPS)
8.2/10 Very good! (22 reviews)
Palo Santo Galapagos Hotel

Palo Santo Galapagos Hotel

£1,591
per person
24 Nov - 1 Dec
found 1 day ago
Return flight included
London (LON) to Isla Baltra (GPS)
8.6/10 Excellent! (23 reviews)

Santa Cruz Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós

Top hotels in Santa Cruz

Hotel Fiesta

Hotel Fiesta

Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
£119
12 Oct - 13 Oct
Hotel Fiesta
Hotel el descanso del Guia

Hotel el descanso del Guia

Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
£55
29 Oct - 30 Oct
8.8/10 Excellent! (234 reviews)
"Espectacular la atención de los recepcionistas, del personal de limpieza y de la persona que atiende en el restaurante. Muchísimas gracias por todo"

Reviewed on 10 Oct 2026

Hotel el descanso del Guia
Maidith Galapagos Inn

Maidith Galapagos Inn

Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
£88
17 Oct - 18 Oct
10/10 Exceptional! (167 reviews)
"El Servicio es excelentem"

Reviewed on 5 Oct 2026

Maidith Galapagos Inn
See all 222 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz travel package cost?
Starting from a low £1,290, a package is your passport to cheap travel. Custom make your Santa Cruz escape by choosing from our wide range of hotels, flights and rental cars.
If I'm not able to travel, can I cancel my Santa Cruz travel package?
We get it — life sometimes gets in the way of your plans. If you've locked in a Santa Cruz travel package and have to change or cancel it, we can help. It's always worth checking out our Customer Service Portal first for information. But in general, if you've taken out your package within 24 hours, you may be able to cancel or amend your itinerary at no cost. If it's been longer than 24 hours, your airline, hotel or car rental company may charge a fee.
How do I get a cheap travel package to Santa Cruz?
Our Santa Cruz holiday packages promise plenty of savings for the savvy explorer. For the best deal, simply bundle your flights, hotels and activities into a handy package. But impressive bargains are only the start of your next memorable adventure. When you book with Expedia, you'll have more than 550 airlines and 1,000,000 properties globally to pick from. No matter your style, there's a holiday package with your name on it.
Does Expedia offer Book Now, Pay Later Santa Cruz holidays?
Expedia has partnered with online lender Klarna to make booking your next trip a little easier on the wallet. Paying by instalment means you can spread the costs of your next adventure, leaving you with more money to spend while you're travelling. Klarna has several payment plans to pick from, so you're sure to find one that suits your budget. Consider these flexible payment options:
  • Pay monthly holidays: Realise your holiday dreams sooner with Klarna's easy monthly instalment plans. If making small repayments each month sounds right for you, choose this option at checkout.
  • Pay in instalments holidays: Like the idea of paying down your holiday in multiple transactions? Consider this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than all of it upfront) makes it easier to hit that "book now" button, go for a low deposit holiday payment plan from Klarna.
How far in advance should I book my Santa Cruz holiday?
It can be difficult to know when is the perfect time to book your Santa Cruz trip. But generally the earlier you book, the more affordable the prices. In some cases, you can book your flights and hotels up to 12 months before departure. If you're thinking of a last-minute getaway, no need to worry! There are fantastic bargains advertised on Expedia every day.
What does an Expedia Santa Cruz travel package include?
Hotels, flights and rental cars — we have them covered. With Expedia, you can create your Santa Cruz travel package however you want. All you have to do is figure out just what you need. Once you've made your booking, you can add extras like experiences and activities. The more you bundle, the bigger the savings!
What should I know before booking a Santa Cruz travel package?
Booking all the parts of your escape together is one of the easiest ways to save. Combine your car rentals, airfares and hotels into a convenient package. But you're not limited to hotels. Expedia offers all types of properties, including holiday rentals such as beachfront villas and city apartments. The list goes on!
Can I choose my airline with a Santa Cruz Expedia travel package?
Expedia has access to more than 550 airline partners worldwide, so you certainly can. Simply pick the airline you want and put together the perfect Santa Cruz trip.

Stay near popular Santa Cruz attractions

A beach with a small island in the distance.
Photo by Elizabeth Oates

Tortuga Bay Beach

9.6/10 (488 reviews)
If a restful holiday is part of your travel plans, Tortuga Bay Beach might be the perfect place to visit during your trip to Bella Vista. While you're in the area, wander around the parks.
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A rocky shoreline with mangrove trees and calm ocean waters.
Photo by Luis Felipe

El Garrapatero Beach

9.2/10 (154 reviews)
Why not spend a care-free afternoon at El Garrapatero Beach during your travels in El Cascajo? While you're in the area, wander around the parks.
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Playa de los Alemanes

8.8/10 (262 reviews)
If a restful holiday is part of your travel plans, Playa de los Alemanes might be the perfect place to visit during your trip to Puerto Ayora. While you're here, you can savour the top-notch restaurants.
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Malecon

9.2/10 (350 reviews)
You can find out about the history of Puerto Ayora with a stop at Malecon. Wander the waterfront and beaches in the area.
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Los Gemelos Sinkholes

9.2/10 (143 reviews)
Commune with nature and explore the great outdoors at Los Gemelos Sinkholes during your travels in Santa Rosa. Wander the waterfront and beaches in the area.
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What to do in Santa Cruz

Bay Tour in Santa Cruz - Galapagos Islands

Bay Tour in Santa Cruz - Galapagos Islands

£45
per adult
100% of travellers recommend
Bay Tour in Santa Cruz - Galapagos Islands
El Chato 2 Reserve Admission Ticket in Santa Cruz Island

El Chato 2 Reserve Admission Ticket in Santa Cruz Island

£6
per traveller
El Chato 2 Reserve Admission Ticket in Santa Cruz Island
Transfer from Santa Cruz Island to San Cristobal Island

Transfer from Santa Cruz Island to San Cristobal Island

£71
per adult
Transfer from Santa Cruz Island to San Cristobal Island
See all activities in Santa Cruz

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.