Title: Guatemala Spa Hotels, Mexico and Central America: Guatemala Hotel Guide | Expedia.co.uk [Guatemala Travel Guide](https://expedia.co.uk/Guatemala.dx71)[Guatemala Hotels](https://expedia.co.uk/Destinations-In-Guatemala.d71.Hotel-Destinations)[Holiday Rentals in Guatemala](https://expedia.co.uk/Destinations-In-Guatemala.d71.Holiday-Rental-Destinations)[Guatemala Flights](https://expedia.co.uk/Destinations-In-Guatemala.d71.Flight-Destinations)[Guatemala Car Hire](https://expedia.co.uk/Destinations-In-Guatemala.d71.Car-Hire-Destinations)[Guatemala Holidays](https://expedia.co.uk/Guatemala.d71.Holidays-City-Breaks) ![Guatemala which includes a sunset, mountains and a lake or waterhole](https://images.trvl-media.com/place/6204165/c57108e9-cba4-4f34-bbef-aa2c2cae5310.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6204165/c57108e9-cba4-4f34-bbef-aa2c2cae5310.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Guatemala Accommodation: Most Popular Cities to Stay ![](https://images.trvl-media.com/place/180589/2835d248-1f96-42ee-9c08-51dbf560c58e.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Antigua Guatemala [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Spa-Hotels.0-0-d180589-tSpaHotels.Travel-Guide-Filter-Hotels) ## Check availability on Guatemala Spa Hotels Tonight [3 Feb - 4 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=71&startDate=2026-02-03&endDate=2026-02-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [4 Feb - 5 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=71&startDate=2026-02-04&endDate=2026-02-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=71&startDate=2026-02-06&endDate=2026-02-08&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=71&startDate=2026-02-13&endDate=2026-02-15&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Guatemala hotels with a spa ![Couples treatment room(s), sauna, hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/3d7ede74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/b78e5b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/7c0f8307.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/223211d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Museo Spa Casa Santo Domingo [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information) Barrio de La Concepción 9.2/10 Wonderful (1,037 reviews) "Great unique place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £246 includes taxes & fees 4 Feb - 5 Feb [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2600000/2594900/2594806/6b654151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/3000000/2600000/2594900/2594806/f9e92aec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2600000/2594900/2594806/620d8dc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor treatment area, sauna, hot springs/mineral springs, aromatherapy](https://images.trvl-media.com/lodging/3000000/2600000/2594900/2594806/7ef4dd36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Regis Hotel & Spa [](https://www.expedia.co.uk/Panajachel-Hotels-Regis-Hotel-Spa.h2594806.Hotel-Information) Panajachel 8.8/10 Excellent (676 reviews) "Friendly staff, clean rooms. Great breakfast" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Henk £58 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Panajachel-Hotels-Regis-Hotel-Spa.h2594806.Hotel-Information) ![Sauna, hot tub, steam room, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/08119561.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/57bcd3b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/35eddbd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3860000/3856200/3856168/014bd4a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Los Pasos Boutique Hotel & Spa [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Los-Pasos.h3856168.Hotel-Information) Antigua Guatemala 9.4/10 Exceptional (1,001 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) BETTE £140 includes taxes & fees 6 Mar - 7 Mar [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Los-Pasos.h3856168.Hotel-Information) ![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/321f0a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/4c5f3e54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/78fae458.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/e348ecdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Barceló Guatemala City [](https://www.expedia.co.uk/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information) Zona 9 9.2/10 Wonderful (3,192 reviews) "Very nice and near to airport. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose £70 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information) ![Santo Cielo, Cabaña Familiar 2 Camas Matrimoniales | Garden view](https://images.trvl-media.com/lodging/14000000/13010000/13000700/13000682/73d07483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cabin | Mountain view](https://images.trvl-media.com/lodging/14000000/13010000/13000700/13000682/b07d7284.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Bungalow, 3 Bedrooms, Mountain View, Mountainside | In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/14000000/13010000/13000700/13000682/d44b2105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Bungalow, 3 Bedrooms, Mountain View, Mountainside | In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/14000000/13010000/13000700/13000682/75e06d49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Santo Cielo by Casa Santo Domingo [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Santo-Cielo-By-Casa-Santo-Domingo.h13000682.Hotel-Information) Antigua Guatemala 9.4/10 Exceptional (526 reviews) "Amazing attention from the staff, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jorge £198 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Santo-Cielo-By-Casa-Santo-Domingo.h13000682.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/664dd097.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor wedding](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/e102ab87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/da5ce8e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/5600/5545/b3d7f8e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Porta Hotel Antigua [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Porta-Hotel-Antigua.h5545.Hotel-Information) Antigua Guatemala 9.4/10 Exceptional (1,004 reviews) "Friendly staff and very clean rooms. Great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George £155 includes taxes & fees 18 Feb - 19 Feb [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Porta-Hotel-Antigua.h5545.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/180000/174100/174075/967864a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/180000/174100/174075/a9440f1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/180000/174100/174075/95d0cc8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/180000/174100/174075/4de274a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Camino Real, Guatemala [](https://www.expedia.co.uk/Guatemala-City-Hotels-The-Westin-Camino-Real.h174075.Hotel-Information) Zona 10 9.2/10 Wonderful (1,005 reviews) "It was very nice Great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dagoberto Alejandro £128 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Guatemala-City-Hotels-The-Westin-Camino-Real.h174075.Hotel-Information) ![Couples treatment room(s), sauna, steam room, hot stone massages](https://images.trvl-media.com/lodging/1000000/50000/48600/48502/118145aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/50000/48600/48502/11a701a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/48600/48502/26383134.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/50000/48600/48502/c9c02249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tikal Futura Hotel & Convention Center [](https://www.expedia.co.uk/Guatemala-City-Hotels-Grand-Tikal-Futura-Hotel.h48502.Hotel-Information) Zona 11 9.2/10 Wonderful (1,005 reviews) "Beautiful place to stay with amazing views! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nate £128 includes taxes & fees 18 Feb - 19 Feb [](https://www.expedia.co.uk/Guatemala-City-Hotels-Grand-Tikal-Futura-Hotel.h48502.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/e88ac778.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/2c45bacb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/6a239fb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/6fd1f9d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Camino Real Antigua [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Camino-Real-Antigua.h3084914.Hotel-Information) Historic Center 9.6/10 Exceptional (1,005 reviews) "Great hotel and the food and service is amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felipe £163 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Camino-Real-Antigua.h3084914.Hotel-Information) ![Body treatments, body scrubs, facials, manicures and pedicures](https://images.trvl-media.com/lodging/7000000/6450000/6442800/6442800/226a4280.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/7000000/6450000/6442800/6442800/e3eb72b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Fusion cuisine, pool views ](https://images.trvl-media.com/lodging/7000000/6450000/6442800/6442800/a663805b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6450000/6442800/6442800/9956d973.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kawilal Hotel [](https://www.expedia.co.uk/Amatitlan-Hotels-Kawilal-Hotel.h6442800.Hotel-Information) Amatitlan 9.0/10 Wonderful (134 reviews) "The property is absolutely gorgeous and the staff is wonderful. On site restaurant is small but a decent amount to select from to eat. Rooms are clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rochelle [](https://www.expedia.co.uk/Amatitlan-Hotels-Kawilal-Hotel.h6442800.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-17&endDate=2026-02-18®ionId=71&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Guatemala-Spa-Hotels.0-0-d71-tSpaHotels.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Guatemala-Spa-Hotels.0-0-d71-tSpaHotels.Hotel-Filter-Destinations) ## Top Guatemala Hotel Reviews ![Hotel Biltmore Guatemala](https://images.trvl-media.com/lodging/2000000/1400000/1397600/1397563/1b77a837_y.jpg) ### Hotel Biltmore Guatemala 10/10 Excellent "Very helpful staff. Room was bright and clean" [](https://expedia.co.uk/Guatemala-City-Hotels-Hotel-Biltmore-Guatemala.h1397563.Hotel-Information) ![Hotel Museo Spa Casa Santo Domingo](https://images.trvl-media.com/lodging/2000000/1250000/1246600/1246555/20929971_y.jpg) ### Hotel Museo Spa Casa Santo Domingo 10/10 Excellent "From the moment I stepped into Casa Santo Domingo, I felt like I had entered another world. This place is not just a museum — it’s an experience that wraps you in history, beauty, and tranquility all at once. Walking through the ancient stone corridors and peaceful courtyards, I could feel the soul of Antigua all around me. Every corner tells a story, and every detail feels thoughtfully preserved and lovingly presented. The museum exhibits are fascinating and diverse, blending colonial art, archaeological treasures, and contemporary pieces in a way that feels natural and inspiring. I loved how the ruins themselves are part of the display — it makes the history feel alive rather than distant. The gardens are breathtaking, perfect for slowing down, reflecting, and simply soaking in the atmosphere. It’s one of those rare places where you don’t feel rushed; instead, you’re invited to wander and truly connect. What made my visit especially memorable was the sense of calm and wonder I felt throughout the entire experience. Casa Santo Domingo manages to be grand yet intimate, educational yet deeply emotional. I left feeling inspired, grateful, and completely in love with Guatemala’s rich cultural heritage. This is a must-visit in Antigua — a place I would happily return to again and again. " [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Museo-Spa-Casa-Santo-Domingo.h1246555.Hotel-Information) ![The Westin Camino Real, Guatemala](https://images.trvl-media.com/lodging/1000000/180000/174100/174075/37599208_y.jpg) ### The Westin Camino Real, Guatemala 10/10 Excellent "Great staff and room service " [](https://expedia.co.uk/Guatemala-City-Hotels-The-Westin-Camino-Real.h174075.Hotel-Information) ![Barceló Guatemala City](https://images.trvl-media.com/lodging/1000000/10000/2500/2495/78fae458_y.jpg) ### Barceló Guatemala City 10/10 Excellent "The room was spotless and really comfortable. I had a great view of the city and the pool. I loved this hotel and the Barcelo also has a great gym spa and steamroom. 10/10 highly recommend. " [](https://expedia.co.uk/Guatemala-City-Hotels-Barcelo-Guatemala-City.h2495.Hotel-Information) ![Hyatt Centric Guatemala City](https://images.trvl-media.com/lodging/20000000/19320000/19317600/19317570/b1a04679_y.jpg) ### Hyatt Centric Guatemala City 10/10 Excellent "Excellent location, Cortes’s staff, beautiful installations, good wifi, shower, gym, just an excellent combination for an enjoyable stay." [](https://expedia.co.uk/Guatemala-City-Hotels-Hyatt-Centric-Guatemala-City.h19317570.Hotel-Information) ![Hotel Casa Carmina ](https://images.trvl-media.com/lodging/112000000/111140000/111131100/111131046/1a3fcc86_y.jpg) ### Hotel Casa Carmina 10/10 Excellent "Great location near a lot of good restaurants " [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Casa-Carmina.h111131046.Hotel-Information) ![Porta Hotel del Lago](https://images.trvl-media.com/lodging/1000000/200000/198000/197985/f525cec0_y.jpg) ### Porta Hotel del Lago 10/10 Excellent "Great location, amenities and staff. " [](https://expedia.co.uk/Panajachel-Hotels-Porta-Hotel-Del-Lago.h197985.Hotel-Information) ![Hotel Camino Real Antigua](https://images.trvl-media.com/lodging/4000000/3090000/3085000/3084914/17346378_y.jpg) ### Hotel Camino Real Antigua 10/10 Excellent "Exceeded our expectations! This property is beautiful, rooms are clean, hot showers, staff was lovely. Would stay again!" [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Camino-Real-Antigua.h3084914.Hotel-Information) ![Hotel Soleil La Antigua](https://images.trvl-media.com/lodging/2000000/1520000/1517400/1517336/93bfa68c_y.jpg) ### Hotel Soleil La Antigua 10/10 Excellent "Amazing place " [](https://expedia.co.uk/Antigua-Guatemala-Hotels-Hotel-Soleil-La-Antigua.h1517336.Hotel-Information)