TOP Business Hotels in Daniel Island, SC for 2026

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Our top choices for Daniel Island business-friendly hotels

A spacious dining area with high ceilings, large windows, and a variety of seating options including tables and chairs.

1. Hampton Inn Charleston - Daniel Island

Charleston

Teresa

includes taxes & fees

23 Nov - 24 Nov

An outdoor patio area with a fire pit, seating, and a covered section.

2. Home2 Suites by Hilton Charleston Daniel Island

Charleston

Gretchen

includes taxes & fees

6 Dec - 7 Dec

A covered outdoor area with a pool, palm trees, and lounge chairs.

3. The Beach Club at Charleston Harbor Resort and Marina

Mount Pleasant

Robert

includes taxes & fees

22 Nov - 23 Nov

A pool area with lounge chairs and palm trees.

4. Harborside at Charleston Harbor Resort and Marina

Mount Pleasant

Heather

includes taxes & fees

18 Nov - 19 Nov

A pool area with lounge chairs and palm trees, surrounded by a building with a sign that reads 'hotel indigo'.

5. Hotel Indigo Mount Pleasant by IHG

Mount Pleasant

Mary Beth

includes taxes & fees

6 Dec - 7 Dec

A swimming pool with lounge chairs and umbrellas, surrounded by trees and a building with multiple windows.

6. Holiday Inn Express & Suites Mt. Pleasant by IHG

Mount Pleasant

Thomas

includes taxes & fees

15 Nov - 16 Nov

A modern kitchen with a large island, bar stools, framed pictures on the wall, and a view of the outside.

7. Quality Inn Mt. Pleasant - Charleston

Mount Pleasant

GENELL

includes taxes & fees

29 Nov - 30 Nov

A hotel reception area with a wooden reception desk, a digital screen, and a wall-mounted sign.

8. Sleep Inn Mt. Pleasant - Charleston

Mount Pleasant

Matthew

includes taxes & fees

1 Dec - 2 Dec

A spacious lobby with a high ceiling, a mezzanine level, and multiple seating areas including sofas and chairs.

9. Comfort Inn & Suites Patriots Point

Mount Pleasant

Vita

includes taxes & fees

29 Nov - 30 Nov

A hotel lobby with a bar area, multiple dining tables, and chairs.

10. Hilton Garden Inn Charleston / Mt. Pleasant

Mount Pleasant

Katie

includes taxes & fees

19 Nov - 20 Nov

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Top Daniel Island Hotel Reviews

Home2 Suites by Hilton Charleston Daniel Island

Charleston

10/10 Excellent

Ian

The Beach Club at Charleston Harbor Resort and Marina

Mount Pleasant

10/10 Excellent

Anne

Holiday Inn Express & Suites Mt. Pleasant by IHG

Mount Pleasant

10/10 Excellent

joanne

A modern bar area with a wooden ceiling, bar stools, and a counter.

Cambria Hotel Mount Pleasant – Charleston

Mount Pleasant

10/10 Excellent

Daniel

Hotel Indigo Mount Pleasant by IHG

Mount Pleasant

10/10 Excellent

Lovely hotel with pool, bar & restaurant. Standard rooms with two queens are comfy & suitable, but not massive, so don’t expect extra space. Decor is clean and pleasant & well maintained but I wouldn’t say it’s very modern. The pool area with sun beds is lovely. The hotel have plenty of beach towels which you can also borrow for your day at the beach. If you book including breakfast you get a voucher which entitles each guest to 1 drink and 1 breakfast entree. Any extras you pay for. ...

Sally

A hotel lobby with seating areas, a reception desk, and decorative lighting.

Tru by Hilton Mt Pleasant Charleston

Mount Pleasant

10/10 Excellent

irena

A rooftop pool area with a hot tub, lounge chairs, and a covered seating area.

Drury Plaza Hotel North Charleston

Centre Pointe

10/10 Excellent

Geoffrey

A narrow brick pathway flanked by buildings with balconies and potted plants.

Hilton Club Liberty Place Charleston

Charleston Historic District

10/10 Excellent

Coleen

A spacious conference room with a large round table and multiple chairs, large windows offering views of a highway and buildings, and a wooden ceiling with recessed lighting.

Staybridge Suites Charleston - Mount Pleasant by IHG

Mount Pleasant

10/10 Excellent

Really pleased with our stay at Staybridge. Had not realised breakfast was included, so that was a bonus! And the breakfast offering was lovely, plenty of it, plenty of choice, well presented.... Staff were all helpful, friendly and efficient, rooms and everywhere spotlessly clean, new towels every day. Facilities? No evening restaurant, ( but thats why they were suites with kitchenettes), swimming pool was merely a plunge pool and right next to the car park! Thanks Staybridge for a great...

Geoffrey

A spacious lobby with a sofa, chairs, and a coffee table, featuring a wooden floor and decorative lighting.

Hampton Inn & Suites Charleston Airport

Centre Pointe

10/10 Excellent

T A

A spacious bar area with high stools, a long wooden bar counter, and a kitchen area with shelves and appliances.

The Restoration

Charleston Historic District

10/10 Excellent

Peter

A modern hotel with a glass facade, a covered entrance, and a clear sky.

Hyatt Place Charleston Airport/Convention Center

North Charleston

10/10 Excellent

Christopher

A modern kitchen with a central island, a chalkboard menu, and a sign promoting waffles.

Hampton Inn Charleston/Mount Pleasant-Patriots Point

Mount Pleasant

10/10 Excellent

Suzanne

Hilton Garden Inn Charleston / Mt. Pleasant

Mount Pleasant

8/10 Good

Christopher

A table set with a bottle of champagne, two glasses, a lantern, and a small plate of fruit.

French Quarter Inn

Charleston Historic District

10/10 Excellent

Louisa

A modern hotel lobby with a dining area, a bar, and a television.

Springhill Suites by Marriott Charleston Mount Pleasant

Mount Pleasant

10/10 Excellent

Anonymous traveller

Frequently Asked Questions

Why book your business hotel in Daniel Island with Expedia?

With top amenities like conference rooms, 24-hour front desk support and on-site cafés, our business hotels come with everything you'll need to close your important deal — and then relax! Enter your travel dates and destination and Expedia will help you with everything else.

How can I find cheap business hotels in Daniel Island?

Expedia can help you easily find cheap business hotels in Daniel Island. Simply go to the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work comfortably and efficiently, like free WiFi and included breakfast. You can also choose your hotel star rating and budget to keep costs under control.

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Search Business Hotels in Daniel Island

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Daniel Island business-friendly hotels

1. Hampton Inn Charleston - Daniel Island

2. Home2 Suites by Hilton Charleston Daniel Island

3. The Beach Club at Charleston Harbor Resort and Marina

4. Harborside at Charleston Harbor Resort and Marina

5. Hotel Indigo Mount Pleasant by IHG

6. Holiday Inn Express & Suites Mt. Pleasant by IHG

7. Quality Inn Mt. Pleasant - Charleston

8. Sleep Inn Mt. Pleasant - Charleston

9. Comfort Inn & Suites Patriots Point

10. Hilton Garden Inn Charleston / Mt. Pleasant

Top Daniel Island Hotel Reviews

Home2 Suites by Hilton Charleston Daniel Island

10/10 Excellent

Frequently Asked Questions

Why book your business hotel in Daniel Island with Expedia?

How can I find cheap business hotels in Daniel Island?

Explore a world of travel with Expedia