Title: TOP Business Hotels in Daniel Island, SC for 2026 | Expedia.co.uk [Daniel Island Travel Guide](https://expedia.co.uk/Daniel-Island.dx6334692)[Hotels in Daniel Island](https://expedia.co.uk/Daniel-Island-Hotels.d6334692.Travel-Guide-Hotels)[Holiday Rentals in Daniel Island](https://expedia.co.uk/Daniel-Island-Holiday-Rentals.d6334692.Travel-Guide-HolidayRentals)[Flights to Daniel Island](https://expedia.co.uk/Cheap-Flights-To-Daniel-Island.d6334692.Travel-Guide-Flights)[Things to do in Daniel Island](https://expedia.co.uk/Things-To-Do-In-Daniel-Island.d6334692.Travel-Guide-Activities)[Daniel Island Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Daniel-Island.d6334692.Car-Hire-Guide)[Daniel Island Holidays](https://expedia.co.uk/Daniel-Island.d6334692.Holidays-City-Breaks) ![Wando River Bridge South Carolina](https://images.trvl-media.com/place/6334692/736f2b38-c4ee-4b48-9c35-23a79062b798.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6334692/736f2b38-c4ee-4b48-9c35-23a79062b798.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Daniel Island Business Hotels Tonight [10 Mar - 11 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6334692&startDate=2026-03-10&endDate=2026-03-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [11 Mar - 12 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6334692&startDate=2026-03-11&endDate=2026-03-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6334692&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [20 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6334692&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Daniel Island business-friendly hotels ![Terrace/patio](https://images.trvl-media.com/lodging/40000000/39230000/39228100/39228057/w3839h2586x0y1-1e06adef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/40000000/39230000/39228100/39228057/8c204e15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/40000000/39230000/39228100/39228057/055c69d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/40000000/39230000/39228100/39228057/9335301d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Charleston Daniel Island [](https://www.expedia.co.uk/Charleston-Hotels-Home2-STE-Charleston-Daniel-Island.h39228057.Hotel-Information) Charleston 9.4/10 Exceptional (518 reviews) "So clean, great amenities and excellent breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susan £159 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Charleston-Hotels-Home2-STE-Charleston-Daniel-Island.h39228057.Hotel-Information) ![2 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/14000000/13200000/13199200/13199113/3d164b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; seafood, al fresco dining ](https://images.trvl-media.com/lodging/14000000/13200000/13199200/13199113/821fff18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/14000000/13200000/13199200/13199113/cc2594cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/14000000/13200000/13199200/13199113/ecbceb02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Beach Club at Charleston Harbor Resort and Marina [](https://www.expedia.co.uk/Charleston-Hotels-The-Beach-Club-At-Charleston-Harbor-Resort-And-Marina.h13199113.Hotel-Information) Mount Pleasant 9.2/10 Wonderful (1,016 reviews) "Absolutely love this resort! So many amenities, perfect location and the room was huge and clean. We’ll definitely return!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristy £239 includes taxes & fees 11 Mar - 12 Mar [](https://www.expedia.co.uk/Charleston-Hotels-The-Beach-Club-At-Charleston-Harbor-Resort-And-Marina.h13199113.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/180000/172500/172428/7bc61f07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/180000/172500/172428/c4008a73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed | In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/1000000/180000/172500/172428/8da9e4a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/180000/172500/172428/550b5b0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn At Middleton Place [](https://www.expedia.co.uk/Charleston-Hotels-The-Inn-At-Middleton-Place.h172428.Hotel-Information) Charleston 9.0/10 Wonderful (1,007 reviews) "Fantastic and beautiful grounds" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Srinadh £146 includes taxes & fees 17 Mar - 18 Mar [](https://www.expedia.co.uk/Charleston-Hotels-The-Inn-At-Middleton-Place.h172428.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2550000/2545300/2545280/812526c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, coffee/tea maker](https://images.trvl-media.com/lodging/3000000/2550000/2545300/2545280/54b4503c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2550000/2545300/2545280/a3d5489a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/3000000/2550000/2545300/2545280/43a43f45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites North Charleston-University Blvd [](https://www.expedia.co.uk/Charleston-Hotels-Hampton-Inn-Suites-North-Charleston-University-Blvd.h2545280.Hotel-Information) Deer Park 9.0/10 Wonderful (1,009 reviews) "Beds comfortable, breakfast was great, check in was quick and easy" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica £84 includes taxes & fees 17 Mar - 18 Mar [](https://www.expedia.co.uk/Charleston-Hotels-Hampton-Inn-Suites-North-Charleston-University-Blvd.h2545280.Hotel-Information) ![5 outdoor pools, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/82d45fec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/97ba3df9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/ecf408ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/40000/38000/37963/35dd6a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn [](https://www.expedia.co.uk/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) Isle of Palms 8.8/10 Excellent (1,003 reviews) "The hotel is good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emad £288 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Charleston-Hotels-Wild-Dunes-Resort.h37963.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/86000000/85060000/85053300/85053204/00512631.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 6:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/86000000/85060000/85053300/85053204/47404273.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/86000000/85060000/85053300/85053204/w719h479x1y1-883a9c46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed | Bathroom | Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/86000000/85060000/85053300/85053204/5e779df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Starlight Motor Inn [](https://www.expedia.co.uk/North-Charleston-Hotels-Starlight-Motor-Inn.h85053204.Hotel-Information) North Charleston 9.4/10 Exceptional (639 reviews) "The room was super clean, bathroom was spotless, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £88 includes taxes & fees 17 Mar - 18 Mar [](https://www.expedia.co.uk/North-Charleston-Hotels-Starlight-Motor-Inn.h85053204.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/530000/526400/526312/d93045be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/530000/526400/526312/5962b937.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/530000/526400/526312/0ab1373f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/530000/526400/526312/fab593e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay by Best Western Summerville Flowertown [](https://www.expedia.co.uk/Charleston-Hotels-Sleep-Inn-Summerville-Charleston.h526312.Hotel-Information) Summerville 7.2/10 Good (458 reviews) "Great place great day" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Billy £74 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/Charleston-Hotels-Sleep-Inn-Summerville-Charleston.h526312.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/f77e4dbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/b6433898.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/d3a20cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/880000/879100/879014/2b0df1ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Charleston Mount Pleasant [](https://www.expedia.co.uk/Charleston-Hotels-Residence-Inn-By-Marriott-Charleston-Mount-Pleasant.h879014.Hotel-Information) Mount Pleasant 8.8/10 Excellent (191 reviews) "The room was clean, staff was friendly. It was a great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica £128 includes taxes & fees 16 Mar - 17 Mar [](https://www.expedia.co.uk/Charleston-Hotels-Residence-Inn-By-Marriott-Charleston-Mount-Pleasant.h879014.Hotel-Information) ![Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/990000/987500/987409/df3f9f82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/990000/987500/987409/c582452b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/990000/987500/987409/b14c7392.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/990000/987500/987409/8dc64424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Magnolia Inn And Suites [](https://www.expedia.co.uk/Charleston-Hotels-Best-Western-Magnolia-Inn-And-Suites.h987409.Hotel-Information) Ladson 8.6/10 Excellent (1,007 reviews) "Spotless room. Wonderful staff. Great breakfast. Would definitely stay there again. Also very fair price. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eunice £79 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Charleston-Hotels-Best-Western-Magnolia-Inn-And-Suites.h987409.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/21000000/20450000/20441400/20441363/7dc0f4f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20450000/20441400/20441363/255dc1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/21000000/20450000/20441400/20441363/3e09ac1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/21000000/20450000/20441400/20441363/6394862f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Summerville by IHG [](https://www.expedia.co.uk/Charleston-Hotels-Holiday-Inn-Express-Suites-Summerville.h20441363.Hotel-Information) Summerville 9.0/10 Wonderful (1,009 reviews) "Great place to stay and good location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dannie £106 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Charleston-Hotels-Holiday-Inn-Express-Suites-Summerville.h20441363.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-24&endDate=2026-03-25®ionId=6334692&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_6334692) ## Top Daniel Island Hotel Reviews ![The Francis Marion Hotel](https://images.trvl-media.com/lodging/1000000/50000/41300/41204/3ad3c4ea_y.jpg) ### The Francis Marion Hotel 8/10 Good "The Francis Marion is a lovely old nostalgic hotel. The location is fantastic. I would suggest upgrading to a bigger room. The rooms seem to be a worn. I think back in the day it was probably a very luxurious hotel. I think the bathrooms could be updated. I think most of the Queen bed rooms were cut in half to make way for more rooms. However the lobby , restaurant , Spa and Exercise room are nice considering the hotel is older. I think with a little bit more renovations it would be the bell of the ball because of it's great location. I woul definitely stay there again. " [](https://expedia.co.uk/Charleston-Hotels-The-Francis-Marion-Hotel.h41204.Hotel-Information) ![Drury Plaza Hotel North Charleston](https://images.trvl-media.com/lodging/1000000/10000/4100/4063/cf0f392b_y.jpg) ### Drury Plaza Hotel North Charleston 10/10 Excellent "Beds were very comfortable and staff was great " [](https://expedia.co.uk/Charleston-Hotels-North-Charleston-Inn.h4063.Hotel-Information) ![Tides Folly Beach, Charleston's Oceanfront Hotel](https://images.trvl-media.com/lodging/1000000/20000/19300/19249/542582f6_y.jpg) ### Tides Folly Beach, Charleston's Oceanfront Hotel 10/10 Excellent "This hotel is set up well for the beach. We had a great time. My only pseudo complaint was an elevator was out and we had to climb the stairs most of the time because the remaining elevator had a really long wait. But other than that it was great. Very helpful staff which really stuck out. " [](https://expedia.co.uk/Charleston-Hotels-Tides-Folly-Beach-Hotel.h19249.Hotel-Information) ![The Ryder Hotel](https://images.trvl-media.com/lodging/1000000/10000/4600/4544/d4e1e925_y.jpg) ### The Ryder Hotel 10/10 Excellent "Friendly staff, amenities, location" [](https://expedia.co.uk/Charleston-Hotels-The-Ryder-Hotel.h4544.Hotel-Information) ![The Vendue](https://images.trvl-media.com/lodging/1000000/180000/172500/172457/479591d2_y.jpg) ### The Vendue 10/10 Excellent "Great place to stay, well located in the historic district! Great customer service. Easy check in and check out! Highly recommended!!" [](https://expedia.co.uk/Charleston-Hotels-The-Vendue.h172457.Hotel-Information) ![Holiday Inn Express & Suites Charleston Dwtn - Westedge by IHG](https://images.trvl-media.com/lodging/1000000/10000/7500/7488/ca8605b9_y.jpg) ### Holiday Inn Express & Suites Charleston Dwtn - Westedge by IHG 10/10 Excellent "excellent hotel at a reasonable price- uber into downtown or 1 mile walk that is enjoyable." [](https://expedia.co.uk/Charleston-Hotels-Holiday-Inn-Express-Charleston-Dwtn-Medical-Area.h7488.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Charleston Riverview](https://images.trvl-media.com/lodging/1000000/20000/17700/17658/e65be6e1_y.jpg) ### La Quinta Inn & Suites by Wyndham Charleston Riverview 10/10 Excellent "Great location staff members where friendly " [](https://expedia.co.uk/Charleston-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Charleston-Riverview.h17658.Hotel-Information) ![Hotel Indigo Mount Pleasant by IHG](https://images.trvl-media.com/lodging/1000000/10000/8300/8255/073e3b6d_y.jpg) ### Hotel Indigo Mount Pleasant by IHG 6/10 Okay "Very pretty but no hot tub. This place ‘looks’ very nice, but there’s no included breakfast. Most surrounding places offer breakfast bar at this price. " [](https://expedia.co.uk/Charleston-Hotels-Hotel-Indigo-Mount-Pleasant.h8255.Hotel-Information) ![Emeline](https://images.trvl-media.com/lodging/1000000/10000/8900/8890/02b86b23_y.jpg) ### Emeline 10/10 Excellent "Hotel Emeline was a 5-star experience. Existing pictures and reviews don't do this place enough justice!!! We were on a girls' trip (4 girls in their early 40's from all over the US) and we would stay back here in a heartbeat if returning to Charleston in the future. The hotel has such a welcoming atmosphere - it's stylish, modern, clean and the staff are wonderful! Not to mention the on site coffee shop and restaurant are both incredible and food and Bev quality were outstanding! We went on a girls' trip for the weekend and were looking for place for 4 of us to be together. The two-king suite was the most perfect set-up with two private bedrooms and a shared bathroom - couldn't ask for more! And it was cheaper than getting two separate rooms anywhere else. Highly recommend this hotel!!!!" [](https://expedia.co.uk/Charleston-Hotels-Emeline.h8890.Hotel-Information) ## Frequently asked questions ### Why book your business hotel in Daniel Island with Expedia? ### How can I find cheap business hotels in Daniel Island? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [4 Star Hotels in Charleston Historic District ](https://www.expedia.co.uk/4Star-Charleston-Historic-District-Charleston-Hotels.s40-n6057948-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Charleston ](https://www.expedia.co.uk/5Star-Charleston-Hotels.s50-0-d179997.Travel-Guide-Filter-Hotels) - [Ansonborough Hotels ](https://www.expedia.co.uk/Ansonborough-Charleston-Hotels.0-n553248635976470456-0.Travel-Guide-Filter-Hotels) - [Serviced Apartments in Charleston ](https://www.expedia.co.uk/Charleston-Apart-Hotels.d179997-aaApartHotels.Travel-Guide-Accommodation) - [Apartments in Charleston ](https://www.expedia.co.uk/Charleston-Apartments.d179997-aaApartments.Travel-Guide-Accommodation) - 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