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This Azuay location boasts a population of some 280,000 people.
The national capital, Quito, is situated 190 miles north of Cuenca, while Santa Isabel is 25 miles to the southwest.
Snap photos, admire the exhibits and learn about our fragile environment at the Amaru Zoo. If your time is limited, grab a map so you can quickly find the park's key exhibits.
Spend a morning enjoying the broad assortment of plants at University of Cuenca's Orchid Garden. The Ecuagenera Orchids and the Cuenca Botanical Garden are also worth a visit.
On a fine day, pick up some lunch and head out to one of the picturesque urban parks, such as Carachulla or Lineal Park. There's also plenty of room for a game or two on the grass at Calderon Park and Santa Isabel Central Park.
Skim some stones, discover the local birdlife and have a bite to eat at Rio Tomebamba.
Do you love nature? El Cajas National Park is just waiting for you.
The area's exhibition spaces are brimming with tales of human endeavor and achievement. Meander through the hallways as you check out the different displays at Museum of Extreme Art and the Inter-American Center of Popular Arts. Also worth considering are the Museum of the Aboriginal Cultures and Manuel Agustin Landivar Museum.
Browse the various specimens on show as you make your way through the overflowing collections of the Pumapungo Archaeological Park.
Art enthusiasts will enjoy the wide range of gallery spaces. Soak up the inspiring atmosphere at the Casa de los Arcos Art Museum, the Museum of Modern Art and the Galeria FVega.
Puente Roto is a striking structure that has been a vital crossing point for local residents over the years.
The area's spiritual side is evidenced at New Cathedral of Cuenca and Gualaceo Church. If you'd be interested to see a couple more religious sites, head to Convent of the Assumption and San Cenaculo Church.
This area is known as a good shopping destination, so don't miss out on a retail fix while you are here. Find a great deal, splash out on a little luxury or just enjoy the atmosphere at Gualaceo Market and Plaza Rotary Market. San Francisco Plaza Market and San Sebastian Plaza are also worth stopping by.
This family-friendly Cuenca hotel is located near the airport, within a 5-minute walk of Civic Plaza and Plaza Rotary Market. Calderon Park and San Blas Park are also within 10 minutes.
Situated in the historical district, this hotel is steps away from Plaza Rotary Market and Civic Plaza. Esqueletologia Museum and Calderon Park are also within 10 minutes.
Situated in Cuenca, this luxury hotel is within 2 miles (3 km) of San Sebastian Plaza, Museum of Modern Art and San Cenaculo Church. Museum of Extreme Art and Church of Santo Domingo are also within 2 miles (3 km).
Situated in the historical district, this hotel is steps away from Esqueletologia Museum and Plaza Rotary Market. Calderon Park and Civic Plaza are also within 5 minutes.
This family-friendly Cuenca hotel is located near the airport, steps away from Calderon Park, New Cathedral of Cuenca and Esqueletologia Museum. Museum of the Canari Identity and Las Conceptas Museum are also within 5 minutes.
Situated in the suburbs, this spa hotel is within 6 miles (10 km) of Ecuagenera Orchids, Lineal Park and Gualaceo Market. Gualaceo Church is 5.9 mi (9.5 km) away.
Situated in Cuenca, this hostal is within a 5-minute walk of Church of Santo Domingo, San Cenaculo Church and Convent of the Assumption. New Cathedral of Cuenca and San Francisco Plaza Market are also within 10 minutes.
Situated in Cuenca, this hotel is within 2 miles (3 km) of San Sebastian Plaza, Museum of Modern Art and San Cenaculo Church. Museum of Extreme Art and University of Cuenca's Orchid Garden are also within 3 miles (5 km).