Title: Cheap Car Hire in Santee, USA - Expedia.co.uk [Santee Travel Guide](https://expedia.co.uk/Santee.dx6678)[Hotels in Santee](https://expedia.co.uk/Santee-Hotels.d6678.Travel-Guide-Hotels)[Flights to Santee](https://expedia.co.uk/Cheap-Flights-To-Santee.d6678.Travel-Guide-Flights)[Things to do in Santee](https://expedia.co.uk/Things-To-Do-In-Santee.d6678.Travel-Guide-Activities)[Santee Holidays](https://expedia.co.uk/Santee.d6678.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/3073/47ddac67-5969-41c0-8843-96304c5986bd.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in Santee, USA ## Search and Compare from Car Companies in Santee ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Santee \* Price found within the past 6 days. Click for updated prices. Fri, 26 Dec - Sat, 27 Dec ### Full Size Toyota Camry or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location 2745 Otay Pacific Dr, Ste #6, Cross Border Xpress Cbx, San Diego, California 92154, USA 20.05 mi from Santee city centre ![Toyota Camry](//mediaim.expedia.com/cars/41/f8359e2f-1f3f-4c65-ac4c-bc85e53c01f5.jpg) #### £115 total found 4 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=32.548230&olon=-116.974830&date1=26/12/2025&date2=27/12/2025&pprfrr=null&tprfrr=115.2&cvrfrr=ZI&ctrfrr=FC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Fri, 26 Dec - Sat, 27 Dec ### Standard Volkswagen Jetta or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location 2745 Otay Pacific Dr, Ste #6, Cross Border Xpress Cbx, San Diego, California 92154, USA 20.05 mi from Santee city centre ![Volkswagen Jetta](//mediaim.expedia.com/cars/41/518390a3-aa30-4ee4-9bb5-1243de3d0866.jpg) #### £115 total found 4 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=32.548230&olon=-116.974830&date1=26/12/2025&date2=27/12/2025&pprfrr=null&tprfrr=115.2&cvrfrr=ZI&ctrfrr=SC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Fri, 26 Dec - Sat, 27 Dec ### Midsize Toyota Corolla or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location 2745 Otay Pacific Dr, Ste #6, Cross Border Xpress Cbx, San Diego, California 92154, USA 20.05 mi from Santee city centre ![Toyota Corolla](//mediaim.expedia.com/cars/41/724f6f6b-c451-44b5-b34e-8d67280e16eb.jpg) #### £134 total found 4 days ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=32.548230&olon=-116.974830&date1=26/12/2025&date2=27/12/2025&pprfrr=null&tprfrr=134.5&cvrfrr=ZI&ctrfrr=IC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) ### Don't see what you're looking for? See all car hire in Santee [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santee,%20California,%20United%20States%20of%20America&dpln=6678&date1=27/12/2025&date2=29/12/2025&crfrr=defaultFlex&SearchType=Place) Lowest prices found within the past 4 days. Prices and availability subject to change. Additional terms may apply. ## Frequently asked questions ### How much is a rental car per day in Santee? ### Can I hire a car from San Diego Intl. Airport (SAN)? ### What happens if I need to cancel my Santee car reservation? ### What types of cars can I rent in Santee? ### Where can I go on a road trip from Santee? > - Anaheim is approximately 90 miles from Santee. Well-known tourist spots like Disneyland® Resort should be high on your list while you're in town. > - Roughly 110 miles away, Los Angeles is also a hit with travellers. Make sure you check out Universal Studios Hollywood while you're in town. It's one of the reasons people love staying a while in this thriving city. > - Lotusland is around 190 miles from Santee and is one of the region's most beautiful nature spots. Pack a picnic lunch and enjoy the fresh air here. ### How do I find the best car hire deals in Santee with Expedia? ### How old do you have to be to hire a car in Santee? ### What do you need to rent a car in Santee? ### What is the cheapest car hire in Santee? ### Can I hire a car for a month or longer in Santee? ### Where can I find a Santee hire car if I am younger than 25? ### Can I drive in Santee with my current driver's license? > - Age restrictions: You must be at least 25 in most states to be able to hire a car, although in some places the minimum age is 21\. We recommend checking local rules and regulations, and with the hire car company before your trip to understand additional terms and conditions. > - Driving limitations: Don't forget to read the fine print before you drive off so you can avoid any unnecessary charges. When hiring a car in the U.S, you typically can't cross country borders into Canada or Mexico, drive on ferries or go off-roading with your hired vehicle. Please read all the rules and regulations before you book! ### Why should I rent a Santee car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | £115 | | Our second best deal of the day: | £134 | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ## Explore a world of travel with Expedia - 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