Title: Cheap Car Hire in Mayo, USA - Expedia.co.uk [Mayo Travel Guide](https://expedia.co.uk/Mayo.dx6286979)[Hotels in Mayo](https://expedia.co.uk/Mayo-Hotels.d6286979.Travel-Guide-Hotels)[Flights to Mayo](https://expedia.co.uk/Cheap-Flights-To-Mayo.d6286979.Travel-Guide-Flights)[Mayo Holidays](https://expedia.co.uk/Mayo.d6286979.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/553248635976197691/42181e6d-fd52-4c3e-bdcb-128d4daebc91.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in Mayo, USA ## Search and Compare from Car Companies in Mayo ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Mayo \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Mayo, Florida, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Mayo,%20Florida,%20United%20States%20of%20America&dpln=6286979&date1=22/12/2025&date2=24/12/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Mayo, Florida, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Mayo,%20Florida,%20United%20States%20of%20America&dpln=6286979&date1=22/12/2025&date2=24/12/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Mayo, Florida, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Mayo,%20Florida,%20United%20States%20of%20America&dpln=6286979&date1=22/12/2025&date2=24/12/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Mayo, Florida, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Mayo,%20Florida,%20United%20States%20of%20America&dpln=6286979&date1=22/12/2025&date2=24/12/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in Mayo [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Mayo,%20Florida,%20United%20States%20of%20America&dpln=6286979&date1=22/12/2025&date2=24/12/2025&crfrr=defaultFlex&SearchType=Place) ## Frequently asked questions ### How much is a rental car per day in Mayo? ### What happens if I need to cancel my Mayo car reservation? ### What types of cars can I rent in Mayo? ### Where can I go on a road trip from Mayo? > - You'll find University of Florida and loads of other intriguing sights in Gainesville. From Mayo, it's about 60 miles away. > - Next stop? It has to be Jacksonville, which is around 95 miles away. Cummer Museum of Art and Gardens is one local draw card you won't want to miss. > - Venture into nature and appreciate the serenity at Siesta Key Beach. It's 200 miles from Mayo. ### How do I find the best car hire deals in Mayo with Expedia? ### How old do you have to be to rent a car in Mayo? ### What do you need to rent a car in Mayo? ### What is the cheapest car hire in Mayo? ### Can I hire a car for a month or longer in Mayo? ### Where can I find a Mayo hire car if I am younger than 25? ### Can I drive in Mayo with my current driver's license? > - Age restrictions: You'll need to be 25 in many states in order to hire a car, although in some places the minimum age is 21\. We recommend checking state and local regulations, and with the car hire company before you go to understand all the regulations that may apply to you. > - Driving limitations: Make sure you read the fine print before you get behind the wheel so you can avoid unnecessary fees. When hiring a car in the United States, you typically can't cross country borders into Canada or Mexico, use car ferries or go off-roading with your hire vehicle. We recommend reading all the rules and regulations before booking! ### Why should I rent a Mayo car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - [Athena Hotels ](https://www.expedia.co.uk/Athena-Hotels.d553248635975848836.Travel-Guide-Hotels) - [Bell Hotels ](https://www.expedia.co.uk/Bell-Hotels.d3000430838.Travel-Guide-Hotels) - [Branford Hotels ](https://www.expedia.co.uk/Branford-Hotels.d6188028.Travel-Guide-Hotels) - [Hotels near Columbia County Courthouse ](https://www.expedia.co.uk/Columbia-County-Courthouse-Hotels.0-l6285994-0.Travel-Guide-Filter-Hotels) - [Cross City Hotels ](https://www.expedia.co.uk/Cross-City-Hotels.d6689.Travel-Guide-Hotels) - [Day Hotels ](https://www.expedia.co.uk/Day-Hotels.d553248635975869176.Travel-Guide-Hotels) - [Dowling Park Hotels ](https://www.expedia.co.uk/Dowling-Park-Hotels.d97729.Travel-Guide-Hotels) - [Fanning Springs Hotels ](https://www.expedia.co.uk/Fanning-Springs-Hotels.d553248634999260133.Travel-Guide-Hotels) - [Fort White Hotels ](https://www.expedia.co.uk/Fort-White-Hotels.d6286968.Travel-Guide-Hotels) - [High Springs Hotels ](https://www.expedia.co.uk/High-Springs-Hotels.d183096.Travel-Guide-Hotels) - 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