Title: Car Hire at Main Street Hyannis, USA - Expedia.co.uk [Hyannis Travel Guide](https://expedia.co.uk/Hyannis.dx1544)[Main Street Hyannis Hotels](https://expedia.co.uk/Main-Street-Hyannis-Hotels.0-l6287458-0.Travel-Guide-Filter-Hotels)[Flights to Hyannis](https://expedia.co.uk/Cheap-Flights-To-Hyannis.d1544.Travel-Guide-Flights)[Things to do in Hyannis](https://expedia.co.uk/Things-To-Do-In-Hyannis.d1544.Travel-Guide-Activities)[Main Street Hyannis Holidays](https://expedia.co.uk/Main-Street-Hyannis.d6287458.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/6287458/3dc1167b-95a0-4295-b537-9961081522cb.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Hire at Main Street Hyannis, USA ## Search and Compare from Car Companies in Main Street Hyannis ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Main Street Hyannis \* Price found within the past 6 days. Click for updated prices. Sat, 28 Mar - Sun, 29 Mar ### Midsize Elite Polestar 2 or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) #### Pick-up location 100 Tomahawk Dr, Boston, Massachusetts 02128, USA 62.55 mi from Main Street Hyannis city centre ![Polestar 2](//mediaim.expedia.com/cars/45/e4397684-d422-4a9d-9618-3a6d9f783c36.jpg) #### £31 total found 7 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.368270&olon=-71.030284&date1=28/03/2026&date2=29/03/2026&pprfrr=null&tprfrr=31.48&cvrfrr=ZT&ctrfrr=JD&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) Sat, 28 Mar - Sun, 29 Mar ### Special EV Manager s Special or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) #### Pick-up location 100 Tomahawk Dr, Boston, Massachusetts 02128, USA 62.55 mi from Main Street Hyannis city centre ![EV Manager s Special](//mediaim.expedia.com/cars/45/83df26d8-dc3e-4dae-9916-6e8bd09b50ad.jpg) #### £31 total found 7 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.368270&olon=-71.030284&date1=28/03/2026&date2=29/03/2026&pprfrr=null&tprfrr=31.48&cvrfrr=ZT&ctrfrr=XX&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22other%22]) Sat, 28 Mar - Sun, 29 Mar ### Compact SUV Chevrolet Trax or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) #### Pick-up location 100 Tomahawk Dr, Boston, Massachusetts 02128, USA 62.55 mi from Main Street Hyannis city centre ![Chevrolet Trax](//mediaim.expedia.com/cars/45/e5049869-5354-4b79-b9ed-1c3a5a8f0f87.jpg) #### £31 total found 7 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.368270&olon=-71.030284&date1=28/03/2026&date2=29/03/2026&pprfrr=null&tprfrr=30.85&cvrfrr=ZT&ctrfrr=CF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Sat, 28 Mar - Sun, 29 Mar ### Midsize SUV Nissan Rogue or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) #### Pick-up location 100 Tomahawk Dr, Boston, Massachusetts 02128, USA 62.55 mi from Main Street Hyannis city centre ![Nissan Rogue](//mediaim.expedia.com/cars/45/1be06a2c-db8d-49a8-8f4f-cb4db24d9990.jpg) #### £32 total found 7 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.368270&olon=-71.030284&date1=28/03/2026&date2=29/03/2026&pprfrr=null&tprfrr=32.29&cvrfrr=ZT&ctrfrr=IF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Wed, 1 Apr - Thu, 2 Apr ### Standard Chevrolet Cruze or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) #### Pick-up location 100 Tomahawk Dr, Boston, Massachusetts 02128, USA 62.55 mi from Main Street Hyannis city centre ![Chevrolet Cruze](//mediaim.expedia.com/cars/45/90787807-9af7-4241-9b58-a7795543b073.jpg) #### £33 total found 14 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.368270&olon=-71.030284&date1=01/04/2026&date2=02/04/2026&pprfrr=null&tprfrr=33.42&cvrfrr=ZT&ctrfrr=SC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Wed, 1 Apr - Thu, 2 Apr ### Full Size Chevrolet Malibu or similar - 5 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) #### Pick-up location 100 Tomahawk Dr, Boston, Massachusetts 02128, USA 62.55 mi from Main Street Hyannis city centre ![Chevrolet Malibu](//mediaim.expedia.com/cars/45/5589fccc-a42b-4acc-8092-e77ea23a122e.jpg) #### £35 total found 14 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.368270&olon=-71.030284&date1=01/04/2026&date2=02/04/2026&pprfrr=null&tprfrr=34.96&cvrfrr=ZT&ctrfrr=FC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Sat, 28 Mar - Sun, 29 Mar ### Economy Chevrolet Spark or similar - 4 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) #### Pick-up location 100 Tomahawk Dr, Boston, Massachusetts 02128, USA 62.55 mi from Main Street Hyannis city centre ![Chevrolet Spark](//mediaim.expedia.com/cars/45/72c58f0a-a81a-48e3-befa-2ee0943c5166.jpg) #### £46 total found 7 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.368270&olon=-71.030284&date1=28/03/2026&date2=29/03/2026&pprfrr=null&tprfrr=46.27&cvrfrr=ZT&ctrfrr=EC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22economy%22]) Sun, 29 Mar - Mon, 30 Mar ### Mini Van Chrysler Pacifica or similar - 7 people - Unlimited mileage ![Thrifty](//mediaim.expedia.com/cars/logos/ZT.png) #### Pick-up location 100 Tomahawk Dr, Boston, Massachusetts 02128, USA 62.55 mi from Main Street Hyannis city centre ![Chrysler Pacifica](//mediaim.expedia.com/cars/45/465d9c89-1a3c-4baf-a83e-3d676fee5fdd.jpg) #### £58 total found 7 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.368270&olon=-71.030284&date1=29/03/2026&date2=30/03/2026&pprfrr=null&tprfrr=58.33&cvrfrr=ZT&ctrfrr=MV&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22minivan%22]) Sat, 28 Mar - Sun, 29 Mar ### Standard Elite SUV Ford Explorer or similar - 7 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location 15 Transportation Way Logan International Airport, Boston, Massachusetts 02128, USA 62.54 mi from Main Street Hyannis city centre ![Ford Explorer](//mediaim.expedia.com/cars/41/c92cbd55-45b2-4fbe-b152-5ae503cf5057.jpg) #### £60 total found 7 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.368333&olon=-71.029722&date1=28/03/2026&date2=29/03/2026&pprfrr=null&tprfrr=59.8&cvrfrr=ZI&ctrfrr=RF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Sat, 28 Mar - Sun, 29 Mar ### Premium Pickup Regular Cab Ford F150 or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) #### Pick-up location 15 Transportation Way, East Boston, Massachusetts 02128, USA 62.5 mi from Main Street Hyannis city centre ![Ford F150](//mediaim.expedia.com/cars/6/b9f0687c-ec07-4124-8b53-27941227757b.jpg) #### £61 total found 7 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.367090&olon=-71.030620&date1=28/03/2026&date2=29/03/2026&pprfrr=null&tprfrr=60.51&cvrfrr=AL&ctrfrr=PP&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22pickup%22]) Sat, 28 Mar - Sun, 29 Mar ### Luxury Audi A4 or BMW 3 Series or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) #### Pick-up location 15 Transportation Way, East Boston, Massachusetts 02128, USA 62.5 mi from Main Street Hyannis city centre ![Audi A4 or BMW 3 Series](//mediaim.expedia.com/cars/6/b4b67bfa-a57e-406e-a7d4-d1dff7808259.jpg) #### £71 total found 7 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.367090&olon=-71.030620&date1=28/03/2026&date2=29/03/2026&pprfrr=null&tprfrr=71.27&cvrfrr=AL&ctrfrr=LC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22luxury%22]) Mon, 30 Mar - Tue, 31 Mar ### Premium Elite Mercedes GLE BMW X5 or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) #### Pick-up location 15 Transportation Way, East Boston, Massachusetts 02128, USA 62.5 mi from Main Street Hyannis city centre ![Mercedes GLE BMW X5](//mediaim.expedia.com/cars/6/dcb7bd16-08f7-4b79-ac45-b858f31e4a46.jpg) #### £85 total found 1 day ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.367090&olon=-71.030620&date1=30/03/2026&date2=31/03/2026&pprfrr=null&tprfrr=85.16&cvrfrr=AL&ctrfrr=UD&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22premium%22]) Tue, 31 Mar - Wed, 1 Apr ### Luxury Elite SUV BMW X7 Range Rover Sport or similar - 5 people - Unlimited mileage ![Alamo](//mediaim.expedia.com/cars/logos/AL.png) #### Pick-up location 15 Transportation Way, East Boston, Massachusetts 02128, USA 62.5 mi from Main Street Hyannis city centre ![BMW X7 Range Rover Sport](//mediaim.expedia.com/cars/6/d56c9f62-2bbf-4fdc-82b3-870bfc563142.jpg) #### £87 total found 15 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.367090&olon=-71.030620&date1=31/03/2026&date2=01/04/2026&pprfrr=null&tprfrr=86.96&cvrfrr=AL&ctrfrr=WF&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22suv%22]) Mon, 30 Mar - Tue, 31 Mar ### Full Size Elite BMW 3 SERIES or similar - 5 people - Unlimited mileage ![Sixt](//mediaim.expedia.com/cars/logos/SX.png) #### Pick-up location 100 Tomahawk Dr, Boston, Massachusetts 02128, USA 62.56 mi from Main Street Hyannis city centre ![BMW 3 SERIES](//mediaim.expedia.com/cars/35/b31b7147-93f8-487d-a013-186a1dd7936c.jpg) #### £89 total found 1 day ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=42.367560&olon=-71.031680&date1=30/03/2026&date2=31/03/2026&pprfrr=83.94&tprfrr=88.63&cvrfrr=SX&ctrfrr=GC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) ### Don't see what you're looking for? See all car hire in Main Street Hyannis [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Main%20Street%20Hyannis,%20Hyannis,%20Massachusetts,%20United%20States%20of%20America&dpln=6287458&date1=02/04/2026&date2=04/04/2026&crfrr=defaultFlex&SearchType=Place) ## Frequently asked questions ### How much is a rental car per day in Main Street Hyannis? ### What happens if I need to cancel my Main Street Hyannis car reservation? ### What types of cars can I rent in Main Street Hyannis? ### Where can I go on a road trip from Main Street Hyannis? > - Make tracks to Boston for an excellent sightseeing experience. About 65 miles from Main Street Hyannis, it's home to tons of amazing attractions, including Fenway Park. > - Why not enjoy the best of Cambridge too? Top tourist attractions to see here include Harvard Square. Cambridge is approximately 65 miles from Main Street Hyannis. > - Head to Mount Washington State Park for a day out in nature. Pack a picnic to enjoy or just recharge your batteries in the fresh air. From Main Street Hyannis, it's approximately 190 miles away. ### How do I find the best car hire deals in Main Street Hyannis with Expedia? ### How old do you have to be to hire a car in Main Street Hyannis? ### What do you need to rent a car in Main Street Hyannis? ### What is the cheapest car hire in Main Street Hyannis? ### Can I hire a car for a month or longer in Main Street Hyannis? ### Where can I find a Main Street Hyannis hire car if I am younger than 25? ### Can I drive in Main Street Hyannis with my current driver's license? > - Age restrictions: You'll need to be 25 in most states to be able to hire a car, although in some places, the minimum age is 21 years. We recommend checking state and local regulations, as well as with the company you're hiring from before you travel to understand additional terms and conditions. > - Driving limitations: Read the fine print before you slide behind the wheel so you can avoid unnecessary fees. When hiring a car in the United States, you typically can't cross country borders into Mexico or Canada, drive on ferries or traverse certain types of rugged terrain with a hired car. We recommend reading all the rules and regulations before booking! ### Why should I rent a Main Street Hyannis car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | £31 | | Our second best deal of the day: | £32 | | Our third best deal of the day: | £33 | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) |