Main Street Hyannis
Visit Main Street Hyannis
Things to do
Cape Cod & Provincetown: Self-Guided Drive & Walk Audio Tour
Massachusetts Self-Guided Audio Tour Bundle: 10+ Tours
Plan a trip to see Main Street Hyannis
Courtyard Resort
Reviewed on 24 Jun 2026
Margaritaville Resort Cape Cod
Reviewed on 21 Jun 2026
Courtyard By Marriott Cape Cod Hyannis
Reviewed on 30 May 2026
Popular places to visit
John F. Kennedy Hyannis Museum
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
Cape Cod Maritime Museum
You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the seaside in this family-friendly area or visit its seafood restaurants.
St. Francis Xavier Church
After visiting St. Francis Xavier Church, make a plan to see the other sights and activities in Hyannis. Wander through the beautiful beaches and waterfront in this family-friendly area.
Hyannis Harbor
See the Cape Cod peninsula from a different perspective by riding a boat out of this picturesque harbor or wandering along its docks and jetties.
John F. Kennedy Memorial
Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial.
Kalmus Beach
Soak up the sun, comb the sands for pretty shells or soar across the waves while windsurfing at this breezy beach.
Top Hotel Deals
Check availability on hotels close to Main Street Hyannis
Hyannis Plaza Hotel
Hyannis Harbor Hotel
Hyannis Travel Inn
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
SeaCoast Inn
Americas Best Value Inn & Suites Hyannis Cape Cod
Anchor In Distinctive Waterfront Lodging
Comfort Inn Hyannis - Cape Cod
