Price: £118, includes taxes & fees, 20 Nov - 21 Nov, for Our top choices for Main Street Hyannis hotels
Review: The hotel has an indoor heated pool which was not available due to repairs. The staff at the desk and serving breakfast are excellent., by ELIZABETH
Price: £68, includes taxes & fees, 15 Nov - 16 Nov, for Our top choices for Main Street Hyannis hotels
Review: The inn was cozy and clean Directions on the phone to get in the room. Of course I was there off season , but great location. Short walk to the beach. Just lovely, and wonderful for a solo traveler., by Ann
Price: £65, includes taxes & fees, 15 Nov - 16 Nov, for Our top choices for Main Street Hyannis hotels
Review: The room was clean and comfortable. We only stayed one night, off season, so we didn't experience the pool. We had our dogs and there was a nice grassy area in which to walk them., by Denise
Price: £195, includes taxes & fees, 15 Nov - 16 Nov, for Our top choices for Main Street Hyannis hotels
Review: Fantastic place!, by Patti
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the seaside in this family-friendly area or visit its seafood restaurants.
After visiting St. Francis Xavier Church, make a plan to see the other sights and activities in Hyannis. Wander through the beautiful beaches and waterfront in this family-friendly area.
You can take time to visit Hyannis Youth & Community Center during your travels to Hyannis. Stroll along the beautiful beaches or visit the shops in the area.
You can spend an afternoon exploring the galleries in Zion Union Heritage Museum during your trip to Hyannis. Make time to visit the area's shops or simply enjoy its seafood restaurants.
Enjoy an outing to Commotion Charters during your stay in Hyannis. Attend a sporting event or simply enjoy the seafood restaurants while you're in the area.
Review: Great stay. Fantastic location for harbour and Hy-line and eating establishments. Accommodation was excellent and super value for money. The staff bent over backwards to help and support. I wish we’d stayed here longer and bypassed Rhode Island!, by Lindsey, 20 October 2026, rated 10/10 Excellent
Address: 92 Route 6A, Yarmouth Port, MA, 02675, US
Location: Yarmouth Port
Star rating: 3.5/5
Guest rating: 10/10 (233 reviews)
Review: We stayed for 4 nights at The Village Inn. Robin and Claire were excellent hosts and very helpful about places to visit and to eat. it was a lovely old house, very comfortable with a pleasant garden and sitting rooms. Breakfast freshly cooked by Robin was delicious. We would certainly return., by Pat & Norman, 14 October 2015, rated 10/10 Excellent
Review: Its hard to describe how relaxing this place is. Tranquil and calming for a perfect break from the world. Adrian is a fantastic host and chef and cannot do enough for you. Breakfast is amazing - you will not need lunch! Location is a great jumping off point to see all of the Cape and is an excellent base to explore from., by Anonymous traveller, 23 May 2019, rated 10/10 Excellent
Review: We highly recommend this lovely Inn as a holiday destination. Centrally located on the Cape with fantastic hosts. The bed linen was so soft with pillows that aid sleep. The breakfasts were so tasty and like a work of art, beautifully presented. We came away feeling relaxed and wanting to return soon. 😁, by She, 25 June 2018, rated 10/10 Excellent
Review: The couple that run this beautiful B&B provide a top-notch service, great breakfast whilst relaxed in lovely surroundings. Not for children really as they have some antique and valuable fittings etc, but great for some romance & relaxation., by Nick, 24 November 2014, rated 10/10 Excellent
Review: What an exquisite place to stay! Large room, beautiful furnishings, lovely grounds, gorgeous home cooked breakfasts. And Amy is such a warm friendly and helpful host., by Martin, 2 October 2024, rated 10/10 Excellent
Review: Brilliant place to stay, lovely building, room and gardens, perfectly placed for the beach and other adventures. Breakfasts are fantastic, a real treat! And the owners Marco and Angelo and their team were absolutely on their game, great attention to detail, amazing service and generally lovely people! Couldn’t recommend it more!, by Liam, 23 August 2024, rated 10/10 Excellent
Address: 135 Route 28, West Yarmouth, MA, 02673, US
Location: West Yarmouth
Star rating: 4/5
Guest rating: 9.2/10 (423 reviews)
Review: More style than substance. Just about gets away with it but our room was described with a bath but only had a shower. Met with shrug by staff. Food choice average. As seems to be usual nowadays expected to give 20% plus tip for serving myself at a counter., by Martin, 15 August 2026, rated 10/10 Excellent
Review: We have just returned from 2 weeks trip to USA (NYC, Boston, Cape Cod, Rhode Island, Miami and Florida Keys) and the Escape Inn was by far the best hotel we stayed in. The family suite was so spacious, light, beautifully decorated and spotlessly cleaned. The owners were very welcoming and friendly. The breakfast was delicious, with plenty of choice. The only shame was we didn't get to use the swimming pool (too cold) and the icecream shop next door was closed for the season! We will just have to..., by Vicky, 8 November 2016, rated 10/10 Excellent
Review: Beautiful place to stay. Great location for beaches & base for exploring further afield. Run by a lovely couple who were helpful and friendly., by Hannah, 4 November 2024, rated 10/10 Excellent
Address: 99 Main Street, Route 28, West Yarmouth, MA, 02673, US
Location: West Yarmouth
Star rating: 2.5/5
Guest rating: 8.8/10 (1000 reviews)
Review: Overall, this was a wonderful stay from start to finish. I would absolutely return and recommend it to anyone looking for a relaxing, high-quality hotel experience — and seriously, don’t miss the breakfast lots of choice. From the moment I arrived, the staff were welcoming, attentive, and genuinely helpful — it set the tone for a great stay. Used the laundry facilities too they were good, by Karen, 14 October 2025, rated 10/10 Excellent
Address: 225 Route 28, West Yarmouth, MA, 02673, US
Location: West Yarmouth
Star rating: 3/5
Guest rating: 8.8/10 (1576 reviews)
Review: A little dated but comfortable, clean and a good choice of breakfast. Lovely area outside to the rear of the Hotel and both pool areas were very nice. Absolutely perfect if travelling with children., by judith, 15 October 2026, rated 10/10 Excellent
Frequently Asked Questions
What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 197 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Hyannis Harbor Hotel and Hyannis Plaza Hotel.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 197 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Centerville Historical Museum and Edward Gorey House feature captivating exhibits. Hyannis Harbor, Sandy Neck Lighthouse and West Parish Meetinghouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Veterans Memorial Park and Dennis Pond Conservation Area are peaceful spots to stop and take in some fresh air.
