Clayton Holidays from £1,183

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Your Clayton Holiday

Lock in a Clayton holiday package and prepare to experience all this lively city has to offer. Consider staying in the neighbourhood of Soulard, which is good for distilleries and craft breweries, bars and pubs and markets. Fill your spare time with tours of St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis, some of the attractions you just have to see during a trip to Clayton. A couple of clicks is all it takes to put together the perfect Clayton holiday on Expedia.

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
per person
18 Oct - 24 Oct
found 1 day ago
Return flight included
Manchester (MAN) to St. Louis (STL)
8.2/10 Very Good! (756 reviews)
I booked online and paid via the app. When I arrived on site they explained they had overbooked and had no rooms available. The staff was amazing and went above and beyond and secured a room at another location. Thank you to the staff for taking care of us.

Reviewed on 26 Jul 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
per person
18 Oct - 24 Oct
found 1 day ago
Return flight included
Manchester (MAN) to St. Louis (STL)
9/10 Wonderful! (1,549 reviews)
For the price, this hotel was great. A cheap clean stopover in St. Louis. We were very happy to have cafes and restaurants within walking distance too! And parking was free.

Reviewed on 30 Jul 2025

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
per person
18 Oct - 24 Oct
found 1 day ago
Return flight included
Manchester (MAN) to St. Louis (STL)
8.4/10 Very Good! (1,000 reviews)
The hotel room was comfortable and well-kept - it’s a good spot for a weekend getaway or a night before flying out from the airport. Good mix of slots and tables.

Reviewed on 24 Jul 2025

The Knight Center at Washington University

The Knight Center at Washington University

2.5 out of 5
per person
18 Oct - 24 Oct
found 1 day ago
Return flight included
Manchester (MAN) to St. Louis (STL)
9.4/10 Exceptional! (337 reviews)
Property was well kept and great location

Reviewed on 29 Jul 2025

Moonrise Hotel

Moonrise Hotel

4 out of 5
Delmar Loop
per person
18 Oct - 24 Oct
found 1 day ago
Return flight included
Manchester (MAN) to St. Louis (STL)
9/10 Wonderful! (1,783 reviews)
Nice visual look and fun encased collectibles to look at.

Reviewed on 29 Jul 2025

Where to stay in Clayton

Find the best Clayton areas and neighborhoods for the activities you enjoy most. Learn more about Clayton
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Downtown St. Louis

3 out of top 10 points of interest in this area
4.5/5(18 area reviews)

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Find hotels in Downtown St. Louis

Top hotels in Clayton

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is £91 per night from 17 Aug to 18 Aug
£91
17 Aug - 18 Aug
includes taxes & fees
8.8/10 Excellent! (2,965 reviews)
"Free breakfast was pretty good with a wide selection."

Reviewed on 27 Jul 2025

Clayton Plaza Hotel & Extended Stay
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is £118 per night from 29 Aug to 30 Aug
£118
29 Aug - 30 Aug
includes taxes & fees
9/10 Wonderful! (128 reviews)
"Room was spacious and bathroom was nice."

Reviewed on 28 Jul 2025

AC Hotel St. Louis Clayton
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is £146 per night from 31 Aug to 1 Sept
£146
31 Aug - 1 Sept
includes taxes & fees
8.8/10 Excellent! (641 reviews)
"Helpful staff"

Reviewed on 26 Jul 2025

Le Méridien St. Louis Clayton
See all 1,795 properties in Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
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Family Friendly Holidays

Frequently asked questions

How much does a Clayton travel package cost?
Maybe less than you imagined — from only £1,183, actually! By bundling hotels, flights and car rentals into a custom-made package, your trip to Clayton is only clicks away.
If I'm not able to travel, can I cancel my Clayton travel package?
Yes, you can cancel your Clayton booking if your plans have been upended. Whether you'll incur a fee or not depends on your hotel, airline or car rental company. It may be possible to change or cancel your booking for free if you booked in the last 24 hours. Head to our Customer Service Portal to find out more.
How do I get a cheap travel package to Clayton?
Bundle your hotels and flights with Expedia to save big bucks on your next adventure. With more than 550 air carriers and 1,000,000 hotel options throughout the world, your Clayton travel package can be customized exactly to suit your travel style. With all that extra cash, why not add one or more exciting experiences and tours? It's an easy way to unlock even more bargains. That dream holiday to Clayton is closer than you thought!
Does Expedia offer Book Now, Pay Later Clayton holidays?
Good news! We do. Expedia has partnered with online lender Klarna to help you conveniently pay for your holiday in manageable instalments. Simply choose the payment plan that suits you best during the checkout process and take the stress out of budgeting for your next trip. Don't forget to bundle your flights, accommodation and activities with Expedia to get the biggest bang for your travel buck. Consider these flexible payment options below:

  • Pay monthly holidays: Klarna has convenient monthly payment plans that suit all types of budgets, so you can escape on that well-earned holiday now.
  • Pay in instalments holidays: If you want to pay off your getaway in multiple transactions, holidays paid in instalments might be the right choice for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: When you stumble on an awesome deal but don't have the full amount yet, Klarna's low deposit holiday plan will help you lock in your escape.

Where should I stay in Clayton?
With lots to explore in Clayton, we suggest you stay near its attractions. St. Louis Zoo, St. Louis Art Museum and Forest Park are some good ones to put on your itinerary.
What are the top hotels in Clayton?
If you'd like to stay in the Demun neighbourhood, some excellent options are Le Méridien St. Louis Clayton and Clayton Plaza Hotel & Extended Stay. North Clayton is also a favourite Clayton area. We recommend Le Méridien St. Louis Clayton or Clayton Plaza Hotel & Extended Stay if you prefer this part of the city.
How far in advance should I book my Clayton holiday?
It's hard to pick the perfect time for airfares, but we generally suggest the earlier, the better. Plenty of international flights on Expedia become available up to a year in advance. If you're booking late, don't worry. Budget prices occasionally appear within a few weeks of departure dates.
What does an Expedia Clayton travel package include?
Packages include flights, hotels and rental cars, but you can combine any of them to create your dream Clayton holiday. You can also add on experiences and activities once you've made your booking. You're in the driver's seat! When you combine your bookings with Expedia, you'll enjoy deals you won't find elsewhere.
What should I know before booking a Clayton travel package?
When you book your flights, hotels and car rentals together, you'll nab amazing discounts. Whether you're planning a mountain getaway in a cabin or prefer to stay in a cosy apartment in the city, Expedia will make it happen for less.
Can I choose my airline with a Clayton Expedia travel package?
Yes, the choice is yours. We have access to over 550 airlines across the globe, so you can design your Clayton escape according to your budget and travel needs.

Things to do

St Louis: City Museum General Admission Ticket

St Louis: City Museum General Admission Ticket

£16
per adult
96% of travellers recommend
St Louis: City Museum General Admission Ticket
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

£24
per adult
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
St Louis Self-Guided Driving and Walking Audio Tour

St Louis Self-Guided Driving and Walking Audio Tour

£13
per traveller
St Louis Self-Guided Driving and Walking Audio Tour
See all activities in St. Louis

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.