
Clayton Holidays
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Clayton Holiday
Lock in a Clayton holiday package and prepare to experience all this lively city has to offer. Consider staying in the neighbourhood of Soulard, which is good for distilleries and craft breweries, bars and pubs and markets. Fill your spare time with tours of St. Louis Zoo, St. Louis Art Museum and Cathedral Basilica of St. Louis, some of the attractions you just have to see during a trip to Clayton. A couple of clicks is all it takes to put together the perfect Clayton holiday on Expedia.
Where to stay in Clayton

Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.
Top hotels in Clayton

Clayton Plaza Hotel & Extended Stay
Wonderful hot breakfast! Very clean room. Friendly, attentive staff! Great price for what you get. Would stay there again.
Reviewed on 8 May 2026

The Ritz-Carlton, St. Louis
When we arrived it was really loud hard to hear customer service as karaoke was going on.
Reviewed on 27 Apr 2026

AC Hotel St. Louis Clayton
Use public parking lot next door, cheaper than valet
Reviewed on 5 May 2026
Frequently asked questions
Things to do

St. Louis Ghost Tour: Sinister Sins & Shadows

Lemp Haunted Neighborhood Walking Tour

Downtown St. Louis Smartphone Guided Audio Walking Tour App
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.













