A wooden sign with 'Welcome to the Cherokee Indian Reservation' written on it, set against a stone wall and a clear blue sky.

£161 Cheap Flights to Cherokee

View £161 flight on Fri, 28 Aug 2026Opens in a new window

Flight 1

Popular airlines to Cherokee

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Cheap round-trip flights to Cherokee

Prices were available within the past 7 days and start at £161 for one-way flights and £336 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply.

Delta
Fri, 28 Aug - Fri, 4 Sept
BUR
Burbank
TYS
Knoxville
£336 Return, found 1 day ago
£336
Return
found 1 day ago
Select Delta flight, departing Fri, 28 Aug from Burbank to Knoxville, returning Fri, 4 Sept, priced at £336 found 1 day ago
American Airlines
Fri, 28 Aug - Fri, 4 Sept
BUR
Burbank
TYS
Knoxville
£389 Return, found 1 day ago
£389
Return
found 1 day ago
Select American Airlines flight, departing Fri, 28 Aug from Burbank to Knoxville, returning Fri, 4 Sept, priced at £389 found 1 day ago
United
Fri, 28 Aug - Fri, 4 Sept
BUR
Burbank
TYS
Knoxville
£401 Return, found 1 day ago
£401
Return
found 1 day ago
Select United flight, departing Fri, 28 Aug from Burbank to Knoxville, returning Fri, 4 Sept, priced at £401 found 1 day ago
Lufthansa
Fri, 6 Nov - Sun, 8 Nov
DUB
Dublin
TYS
Knoxville
£494 Return, found 2 days ago
£494
Return
found 2 days ago
Select Lufthansa flight, departing Fri, 6 Nov from Dublin to Knoxville, returning Sun, 8 Nov, priced at £494 found 2 days ago
KLM
Thu, 5 Nov - Mon, 9 Nov
DUB
Dublin
TYS
Knoxville
£527 Return, found 2 days ago
£527
Return
found 2 days ago
Select KLM flight, departing Thu, 5 Nov from Dublin to Knoxville, returning Mon, 9 Nov, priced at £527 found 2 days ago

Find the cheapest month to fly from Columbus (CMH) to Knoxville (TYS)

February is typically the cheapest month to fly

From £158 - £341 per traveller.

Frequently asked questions

What is the name of Cherokee's airport?
Cherokee is served by multiple airports, but most people prefer McGhee Tyson Airport (TYS).
What airport is best to fly into Cherokee?
If you're flying to Cherokee, you'll likely arrive at McGhee Tyson Airport (TYS) (72 kms (45 miles) from downtown). Asheville Regional Airport (AVL) (72 kms (45 miles) from downtown) is the other major airport that services the city.
How many airlines fly to Cherokee?
There are a total of 8 airlines connecting Cherokee to 26 airports across the world.
Which airlines fly to Cherokee?
Flights to Cherokee are typically run by American Airlines. The greatest number of flights take off from Charlotte, with American Airlines servicing this route the most.
How many nonstop flights are there to Cherokee?
Organising an amazing Cherokee adventure is a piece of cake when there are 543 nonstop flights every week to pick from.
Where are the most popular flights to Cherokee departing from?
Flights to Cherokee from Charlotte, Atlanta and New York airports are the most in demand.
How long is the flight to Cherokee Airport?
Where you depart from determines how long you'll be strapped into your seat. From Charlotte to Cherokee, the average flight time is 1 hour and 8 minutes. From Atlanta it takes about 58 minutes, and from New York it's 2 hours and 23 minutes.
How to book the cheapest flight to Cherokee?
Don't leave booking your flight to Cherokee until the last moment. That's one trick seasoned jet-setters use to get the best prices. Booking ahead means more choices and more affordable flights. Another great way to nab the best deal is to compare all options. If where you're headed has several airports, don't forget to research the cost of flying into a smaller terminal. Finally, another easy way to save some money is be ready to book at a moment's notice. If you come across a terrific bargain, don't think twice — snap it up while you can.
Do you have any tips for my flight to Cherokee?
If you're poorly prepared, airports and flying can be challenging. But there's no need to worry. Follow these handy tips and enjoy a hassle-free start to your getaway in Cherokee. What to pack in your hand luggage:

  • Travelling on a plane can be a great experience if you take the right things. Firstly, you'll need basic toiletries, such as deodorant, toothpaste and a toothbrush, a spare set of clothes and something to read. Next, make room in your bag for your electronic gadgets, chargers, any daily medications and perhaps a blow-up neck pillow too. Lastly, and most importantly, don't forget to bring your passport, travel documents and some money.

Do not pack the following items in your hand luggage:

  • Check carefully that you don't have sharp objects (like a knife or scissors) hiding in one of the zippers of your hand luggage. Other prohibited items include explosive or flammable products, such as bleach and fuel, and liquids and gels in containers larger than 3.4 ounces (100 millilitres).

What to wear on a flight:

  • Your aim here is to be as comfortable as possible. Go for shoes that are easy to slip on and off, dress in loose, natural fibers and don't forget to bring a pullover in case you get chilly in the cabin.
  • Deep vein thrombosis (DVT), a blood clotting condition caused by prolonged periods of inactivity, can be a risk on long-haul flights. Try to wander around the cabin or do some gentle exercises in your seat to improve your circulation.

How to get through airport security fast when flying to Cherokee?
The answer is — be prepared. We've pulled together some tips and tricks for a speedy trip through airport security. Look out Cherokee, here you come:

  • Your boarding pass and travel ID will need to be presented to airport security. Have them easily accessible to avoid fumbling around for them.
  • Your coat, belt, keys and other contents of your pockets, like your earphones, will be required to go through the X-ray machine. Make the whole process easier by removing them before your turn.
  • All electronic devices, including your phone and tablet, must also be separately scanned.
  • Don't forget to remove liquids and gels from your hand luggage. They usually need to be sent through the X-ray machine separately. Each item should be in a container no larger than 3.4 ounces (100 millilitres) and everything must fit in a single quart-size (one litre), clear zip-close bag.
  • The right choice of footwear can save you valuable minutes. Boots and bulky shoes are often required to be removed and separately scanned. Slip-on shoes usually aren't.
  • Avoid taking prohibited items in your carry-on bag. If you have any sharp or pointed objects, put them in your checked baggage. They won't be allowed in the cabin.

Book with confidence

Expedia flights to Cherokee

Searching for cheap flights to Cherokee? No travel company presents more choices than Expedia if you're looking to compare flights to Cherokee. With more airlines, cheaper flights, fewer stops, and more departure and arrival times travellers should ensure they search on Expedia before any holiday to North Carolina. Expedia provides the cheapest flights to many destinations in North Carolina and you may find even greater savings if you combine your flight with a hotel stay in Cherokee.

Expedia is the largest online travel agency which means that Expedia have access to cheap flights. So make sure you check Expedia regularly for these bargain flights because the cheapest airline tickets sell out fast.

Expedia is not only free for everyone to use but it quick and easy to use. Find the lowest flight prices guaranteed and book directly through Expedia. Browse through hundreds of cheap flight offers to find the one that suits your budget by simply inputting your travel dates. Expedia will then find the cheapest flights to Cherokee for that period and let you choose your preferred time and airline. If you need additional assistance, Expedia Customer Service representatives are available from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends. Our capable staff will be able to help you with any questions regarding your Cherokee flight, or other booking questions that may arise. When you book flights with Expedia you can rest assured that you have booked the best flight at the lowest price.

Expedia flights to Cherokee

Travel information

Destination airport
McGhee Tyson
Destination airport IATA code
TYS
Destination city name
Knoxville
Return price
£494

Trending flights to Cherokee

Prices were available within the past 7 days and start at £161 for one-way flights and £336 for round trip, for the period specified. Be sure to select the 'Direct flights only' box above if you are looking for a non stop route. Prices and availability are subject to change. Additional terms apply.

Scandinavian Airlines
Wed, 7 Oct - Sat, 17 Oct
LHR
London
TYS
Knoxville
£592 Return, found 15 hours ago
£592
Return
found 15 hours ago
Select Scandinavian Airlines flight, departing Wed, 7 Oct from London to Knoxville, returning Sat, 17 Oct, priced at £592 found 15 hours ago

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