Title: TOP Central Missouri Spa Hotels for 2025 - Spas in Central Missouri, MO | Expedia.co.uk [Central Missouri Travel Guide](https://expedia.co.uk/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.co.uk/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Holiday Rentals in Central Missouri](https://expedia.co.uk/Central-Missouri-Holiday-Rentals.d6058776.Travel-Guide-HolidayRentals)[Flights to Central Missouri](https://expedia.co.uk/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.co.uk/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-Missouri.d6058776.Car-Hire-Guide)[Central Missouri Holidays](https://expedia.co.uk/Central-Missouri.d6058776.Holidays-City-Breaks) ![Columbia showing wild flowers](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/257000/257714-Central-Missouri.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Central Missouri, MO ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Spa Hotels Tonight [21 Sept - 22 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-09-21&endDate=2025-09-22&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [22 Sept - 23 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-09-22&endDate=2025-09-23&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-09-26&endDate=2025-09-28&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-10-03&endDate=2025-10-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Central Missouri Spa Hotels ![Couples treatment room(s), hot tub, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/4d290838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7a41768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/41084352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa Lake Ozark 7.2/10 Good (1022) "Great all inclusive place." £87 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Couples treatment room(s), steam room, body treatments](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/c54d3975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/64c8ff64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/5bef6d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/bfd40943.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Old Kinderhook Golf Resort Camdenton 9.4/10 Exceptional (726) "Very friendly and accommodating staff! Clean and quiet :) " [](https://www.expedia.co.uk/Osage-Beach-Hotels-The-Lodge-At-Old-Kinderhook-Golf-Resort.h9785264.Hotel-Information) ![Couples treatment room(s), body treatments, hydrotherapy, aromatherapy](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/7d41cdab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/b09c0391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/21eb378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Suite (Two Double Beds) | Terrace/patio](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/1773a780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa Lake Ozark 9.0/10 Wonderful (1001) "Beautiful property....a little pricey, restaurant portions kinda small for the hefty prices...rooms where Beautiful and the beds were comfy! " [](https://www.expedia.co.uk/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/1a33bfc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/9e770f7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/c5b42c11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/cfa9b0fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Courtland Hotel and Day Spa Fort Scott 9.2/10 Wonderful (265) "This is a great place to stay and with easy access to town area!" £64 includes taxes & fees 22 Sept - 23 Sept [](https://www.expedia.co.uk/Pittsburg-Hotels-The-Courtland-Hotel-And-Day-Spa.h1545110.Hotel-Information) ![Sun deck](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout curtains, iron/ironing board, travel cot, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/83344a11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/d8a21312.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/e7bd5e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Lake Resort Lake of the Ozarks Osage Beach 8.2/10 Very good (1012) "Fun place! " £139 includes taxes & fees 23 Sept - 24 Sept [](https://www.expedia.co.uk/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) ![Couples treatment room(s), aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/f1ee0a61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Guest Suite | Premium bedding, down duvets, memory-foam beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/436e9cc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Spa Suite | Premium bedding, down duvets, memory-foam beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/1f413a42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Spa Suite | View from room](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/34923626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hermann Hill Hermann 9.6/10 Exceptional (107) "Beautiful room with tremendous views" £302 includes taxes & fees 29 Sept - 30 Sept [](https://www.expedia.co.uk/Washington-Hotels-Hermann-Hill.h1664659.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-05&endDate=2025-10-06®ionId=6058776&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Spa hotels with pools in Central Missouri ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/d106f50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7a41768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/41084352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa Lake Ozark 7.2/10 Good (1022) £87 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/5bef6d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/11769d77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/8d3e409f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/64c8ff64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Old Kinderhook Golf Resort Camdenton 9.4/10 Exceptional (726) [](https://www.expedia.co.uk/Osage-Beach-Hotels-The-Lodge-At-Old-Kinderhook-Golf-Resort.h9785264.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/21eb378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Suite (Two Double Beds) | Terrace/patio](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/1773a780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Caribbean cuisine ](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/926b808f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/e77a4ef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa Lake Ozark 9.0/10 Wonderful (1001) [](https://www.expedia.co.uk/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Sun deck](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout curtains, iron/ironing board, travel cot, free WiFi](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/83344a11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/d8a21312.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/e7bd5e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Lake Resort Lake of the Ozarks Osage Beach 8.2/10 Very good (1012) £139 includes taxes & fees 23 Sept - 24 Sept [](https://www.expedia.co.uk/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-05&endDate=2025-10-06®ionId=6058776&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&amenities=POOL&openPlayBack=true) ## Spa hotels with hot tubs in Central Missouri ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/d106f50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7a41768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/41084352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa Lake Ozark 7.2/10 Good (1022) £87 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/21eb378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Suite (Two Double Beds) | Terrace/patio](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/1773a780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Caribbean cuisine ](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/926b808f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/e77a4ef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa Lake Ozark 9.0/10 Wonderful (1001) [](https://www.expedia.co.uk/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-05&endDate=2025-10-06®ionId=6058776&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&amenities=HOT_TUB&openPlayBack=true) ## Find out more about Central Missouri ### Top Central Missouri attractions for a relaxing vacation Central Missouri offers a delightful blend of relaxation and adventure, making it a perfect region for travelers seeking hotels with spas. Begin your journey at the serene Lake of the Ozarks, where stunning views and tranquil waters set the tone for a restful getaway. Enjoy a day of boating or fishing, followed by a rejuvenating spa treatment at one of the lakeside resorts. Next, explore the picturesque Ha Ha Tonka State Park, where you can hike through lush trails that lead to breathtaking vistas and the ruins of a historic stone castle, perfect for a leisurely family outing. For a taste of local history, venture to the Missouri State Capitol in Jefferson City, where guided tours showcase the impressive architecture and rich stories of the state's past. Don't miss the charming town of Columbia, home to vibrant arts and culture, where you can indulge in local cuisine before unwinding at a boutique hotel that features a pampering spa. By choosing to stay in this area, you’ll enjoy not only luxurious accommodations but also the convenience of nearby attractions, ensuring a well-rounded and fulfilling escape. ## Top Central Missouri Hotel Reviews ![Inn at Grand Glaize](//images.trvl-media.com/lodging/1000000/70000/60700/60685/a0b4c124_y.jpg) ### Inn at Grand Glaize 10/10 Excellent "I love the lake view you get from the room" [](https://expedia.co.uk/Osage-Beach-Hotels-Inn-At-Grand-Glaize.h60685.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, MO](//images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092_y.jpg) ### Country Inn & Suites by Radisson, Columbia, MO 10/10 Excellent "Clean and comfortable. Friendly staff. Would stay there again. Bed comfortable. " [](https://expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ![Stoney Creek Hotel Columbia](//images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "Room nice and clean. Staff great! And love the atmosphere " [](https://expedia.co.uk/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Wingate by Wyndham - Columbia](//images.trvl-media.com/lodging/1000000/990000/986100/986086/a16387a6_y.jpg) ### Wingate by Wyndham - Columbia 10/10 Excellent "We only stayed one night. Ryan, the manager, was so nice after I messed up the reservation. The hotel was very accommodating. There's a lot of road noise, but it did not prevent us from getting a good night's sleep. Would stay here again." [](https://expedia.co.uk/Columbia-Hotels-Wingate-By-Wyndham-Columbia.h986086.Hotel-Information) ![Margaritaville Lake Resort Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd_y.jpg) ### Margaritaville Lake Resort Lake of the Ozarks 10/10 Excellent "On a busy weekend staff was super helpful" [](https://expedia.co.uk/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) ![Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG](//images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/8a05cd33_y.jpg) ### Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG 10/10 Excellent "Very friendly and helpful." [](https://expedia.co.uk/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Columbia-Univ-Area-Hwy-63.h7677926.Hotel-Information) ![Lodge Of Four Seasons Golf Resort, Marina & Spa](//images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59_y.jpg) ### Lodge Of Four Seasons Golf Resort, Marina & Spa 10/10 Excellent "The only thing I didn't like is that the bathroom did not have safety bars in the shower and no towel racks " [](https://expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Days Inn by Wyndham Osage Beach Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/20000/18400/18390/b506b22f_y.jpg) ### Days Inn by Wyndham Osage Beach Lake of the Ozarks 8/10 Good "Location was within walking distance of decent restaurants and easy access to the highway." [](https://expedia.co.uk/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Apache Flats Hotels](https://www.expedia.co.uk/Apache-Flats-Hotels.d553248635975850469.Travel-Guide-Hotels) - [Hotels near California Country Club](https://www.expedia.co.uk/California-Country-Club-Hotels.0-l553248621594455013-0.Travel-Guide-Filter-Hotels) - [California Hotels](https://www.expedia.co.uk/California-Hotels.d6351831.Travel-Guide-Hotels) - [Adults Only Resorts & in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Adults-Only-Resorts.0-0-d227-tAdultsOnlyResorts.Hotel-Filter-Destinations) - [All-Inclusive Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-All-Inclusive-Hotel.0-0-d227-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Beach Resorts & in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Beach-Hotels.0-0-d227-tBeachHotels.Hotel-Filter-Destinations) - 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