Title: TOP Central Missouri Spa Hotels for 2025 - Spas in Central Missouri, MO | Expedia.co.uk [Central Missouri Travel Guide](https://expedia.co.uk/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.co.uk/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Holiday Rentals in Central Missouri](https://expedia.co.uk/Central-Missouri-Holiday-Rentals.d6058776.Travel-Guide-HolidayRentals)[Flights to Central Missouri](https://expedia.co.uk/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.co.uk/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-Missouri.d6058776.Car-Hire-Guide)[Central Missouri Holidays](https://expedia.co.uk/Central-Missouri.d6058776.Holidays-City-Breaks) ![University of Missouri which includes heritage architecture, a garden and street scenes](https://images.trvl-media.com/place/6093455/6cff96be-1e29-4df3-85b4-5c4b939de401.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Central Missouri, MO - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Spa Hotels Tonight [6 Nov - 7 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-11-06&endDate=2025-11-07&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [7 Nov - 8 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-11-07&endDate=2025-11-08&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Central Missouri Spa Hotels ![Couples treatment room(s), hot tub, body treatments, hydrotherapy](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/4d290838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7a41768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/d106f50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/41084352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa Lake Ozark 7.4/10 Good (1058) "Nice place. Good parking and convenient location to restaurants. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daryla £81 includes taxes & fees 3 Dec - 4 Dec [](https://www.expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Couples treatment room(s), steam room, body treatments](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/c54d3975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/8d3e409f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/bfd40943.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/10000000/9790000/9785300/9785264/64c8ff64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Old Kinderhook Golf Resort Camdenton 9.4/10 Exceptional (737) "Enjoyed the bar! Fantastic old fashioned!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £119 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Osage-Beach-Hotels-The-Lodge-At-Old-Kinderhook-Golf-Resort.h9785264.Hotel-Information) ![Sun deck](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/e7bd5e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/d8a21312.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/30000/21300/21228/a7d33a02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Lake Resort Lake of the Ozarks Osage Beach 8.4/10 Very good (1000) "Rooms nice, clean, beautiful environment, staff friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise £109 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) ![Couples treatment room(s), body treatments, hydrotherapy, aromatherapy](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/7d41cdab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/b09c0391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/21eb378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Caribbean cuisine ](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/926b808f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa Lake Ozark 9.0/10 Wonderful (1000) "Excellent property. Nice & spacious rooms. Good food on property & very nice staff. Dont hesitate to book this spot. You’ll love it!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sheldon [](https://www.expedia.co.uk/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Couples treatment room(s), body treatments, aromatherapy](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/1a33bfc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/f663be7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/c5b42c11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/2000000/1550000/1545200/1545110/9e770f7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Courtland Hotel and Day Spa Fort Scott 9.2/10 Wonderful (270) "This is a great place to stay and with easy access to town area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark £67 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Pittsburg-Hotels-The-Courtland-Hotel-And-Day-Spa.h1545110.Hotel-Information) ![Couples treatment room(s), aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/f1ee0a61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Spa Suite | Premium bedding, down duvets, memory-foam beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/1f413a42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Guest Suite | Premium bedding, down duvets, memory-foam beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/436e9cc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1670000/1664700/1664659/e45a31c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hermann Hill Hermann 9.6/10 Exceptional (109) "private yet near town. Great view and awesome service. Food was outstanding." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bill £302 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Washington-Hotels-Hermann-Hill.h1664659.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-20&endDate=2025-11-21®ionId=6058776&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Central Missouri ### Top Central Missouri attractions for a relaxing vacation Central Missouri offers a delightful blend of relaxation and adventure, making it a perfect region for travelers seeking hotels with spas. Begin your journey at the serene Lake of the Ozarks, where stunning views and tranquil waters set the tone for a restful getaway. Enjoy a day of boating or fishing, followed by a rejuvenating spa treatment at one of the lakeside resorts. Next, explore the picturesque Ha Ha Tonka State Park, where you can hike through lush trails that lead to breathtaking vistas and the ruins of a historic stone castle, perfect for a leisurely family outing. For a taste of local history, venture to the Missouri State Capitol in Jefferson City, where guided tours showcase the impressive architecture and rich stories of the state's past. Don't miss the charming town of Columbia, home to vibrant arts and culture, where you can indulge in local cuisine before unwinding at a boutique hotel that features a pampering spa. By choosing to stay in this area, you’ll enjoy not only luxurious accommodations but also the convenience of nearby attractions, ensuring a well-rounded and fulfilling escape. ## Top Central Missouri Hotel Reviews ![Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG](//images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/8a05cd33_y.jpg) ### Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG 10/10 Excellent "Everything was great" [](https://expedia.co.uk/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Columbia-Univ-Area-Hwy-63.h7677926.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, MO](//images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092_y.jpg) ### Country Inn & Suites by Radisson, Columbia, MO 10/10 Excellent "Great Location. Big room. Low price." [](https://expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ![Wingate by Wyndham - Columbia](//images.trvl-media.com/lodging/1000000/990000/986100/986086/a16387a6_y.jpg) ### Wingate by Wyndham - Columbia 10/10 Excellent "Yes" [](https://expedia.co.uk/Columbia-Hotels-Wingate-By-Wyndham-Columbia.h986086.Hotel-Information) ![Lodge Of Four Seasons Golf Resort, Marina & Spa](//images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59_y.jpg) ### Lodge Of Four Seasons Golf Resort, Marina & Spa 10/10 Excellent "Friendly& helpful staff, clean room. Great place to stay. " [](https://expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Stoney Creek Hotel Columbia](//images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "Room was very nice, clean and comfortable. I am never disappointed when we stay here" [](https://expedia.co.uk/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Days Inn by Wyndham Osage Beach Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/20000/18400/18390/b506b22f_y.jpg) ### Days Inn by Wyndham Osage Beach Lake of the Ozarks 10/10 Excellent "Good" [](https://expedia.co.uk/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) ![Inn at Grand Glaize](//images.trvl-media.com/lodging/1000000/70000/60700/60685/a0b4c124_y.jpg) ### Inn at Grand Glaize 10/10 Excellent "We always stay here when we are in town. This year it was packed due to shootout. We had reserved a dock and ours was takin at the end of the night. The mananagment was very accommodating. They have always been very nice. There door greater there is so great with people." [](https://expedia.co.uk/Osage-Beach-Hotels-Inn-At-Grand-Glaize.h60685.Hotel-Information) ![Margaritaville Lake Resort Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd_y.jpg) ### Margaritaville Lake Resort Lake of the Ozarks 10/10 Excellent "It was a great stay Hotel still needs some upgrades! Bed was squeaky! But overall we had a great time! I would recommend taco nachos at land shark bar they were very good! Souvenirs were way overpriced!" [](https://expedia.co.uk/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Apache Flats Hotels](https://www.expedia.co.uk/Apache-Flats-Hotels.d553248635975850469.Travel-Guide-Hotels) - [Hotels near California Country Club](https://www.expedia.co.uk/California-Country-Club-Hotels.0-l553248621594455013-0.Travel-Guide-Filter-Hotels) - [California Hotels](https://www.expedia.co.uk/California-Hotels.d6351831.Travel-Guide-Hotels) - [Adults Only Resorts & in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Adults-Only-Resorts.0-0-d227-tAdultsOnlyResorts.Hotel-Filter-Destinations) - [All-Inclusive Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-All-Inclusive-Hotel.0-0-d227-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Beach Resorts & in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Beach-Hotels.0-0-d227-tBeachHotels.Hotel-Filter-Destinations) - 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