Title: TOP Business Hotels in Casco Bay Islands, ME for 2025 | Expedia.co.uk [Casco Bay Islands Travel Guide](https://expedia.co.uk/Casco-Bay-Islands.dx553248621532668098)[Hotels in Casco Bay Islands](https://expedia.co.uk/Casco-Bay-Islands-Hotels.d553248621532668098.Travel-Guide-Hotels)[Holiday Rentals in Casco Bay Islands](https://expedia.co.uk/Casco-Bay-Islands-Holiday-Rentals.d553248621532668098.Travel-Guide-HolidayRentals)[Flights to Casco Bay Islands](https://expedia.co.uk/Cheap-Flights-To-Casco-Bay-Islands.d553248621532668098.Travel-Guide-Flights)[Casco Bay Islands Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Casco-Bay-Islands.d553248621532668098.Car-Hire-Guide)[Casco Bay Islands Holidays](https://expedia.co.uk/Casco-Bay-Islands.d553248621532668098.Holidays-City-Breaks) ![](https://mediaim.expedia.com/destination/1/e4a6b1b412662f557ec45267f6320f34.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Casco Bay Islands ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Casco Bay Islands Business Hotels Tonight [19 Sept - 20 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532668098&startDate=2025-09-19&endDate=2025-09-20&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [20 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532668098&startDate=2025-09-20&endDate=2025-09-21&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532668098&startDate=2025-09-19&endDate=2025-09-21&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532668098&startDate=2025-09-26&endDate=2025-09-28&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Casco Bay Islands Business Hotels ## Our top choices for Casco Bay Islands business-friendly hotels ![Sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/2000000/1260000/1250200/1250149/64ae4155.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/2000000/1260000/1250200/1250149/288e8833.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1260000/1250200/1250149/3b35ca04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/2000000/1260000/1250200/1250149/1c4ff179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chebeague Island Inn Chebeague Island 8.8/10 Excellent (76) "Great place to go and relax for a few days." [](https://www.expedia.co.uk/Portland-Hotels-Chebeague-Island-Inn.h1250149.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/16000000/15290000/15283600/15283574/ed84bcb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bailey Island | Living area | 30-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/16000000/15290000/15283600/15283574/2a646798.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area | 30-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/16000000/15290000/15283600/15283574/3542ba9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Great Diamond Island Suite | 1 bedroom, individually decorated, individually furnished](https://images.trvl-media.com/lodging/16000000/15290000/15283600/15283574/7f5fc132.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn On Peaks Island Peaks Island 9.0/10 Wonderful (102) "Excellent little getaway in a very quaint island!" £197 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Portland-Hotels-Inn-On-Peaks-Island.h15283574.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-03&endDate=2025-10-04®ionId=553248621532668098&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Casco Bay Islands Hotel Reviews ![Hampton Inn Portland Downtown - Waterfront](//images.trvl-media.com/lodging/5000000/4490000/4480300/4480291/1dc67cbc_y.jpg) ### Hampton Inn Portland Downtown - Waterfront 10/10 Excellent "Great breakfast. Free island shuttle with stop at hotel." [](https://expedia.co.uk/Portland-Hotels-Hampton-Inn-Portland-Downtown-Waterfront.h4480291.Hotel-Information) ![Germaine Inn South Portland](//images.trvl-media.com/lodging/1000000/30000/23800/23779/b95e6193_y.jpg) ### Germaine Inn South Portland 10/10 Excellent "This location was a welcome surprise. Clean, well managed and affordable. I recommend this facility to anyone staying in the Portland area. " [](https://expedia.co.uk/South-Portland-Hotels-Germaine-Inn-South-Portland.h23779.Hotel-Information) ![Portland Regency Hotel & Spa](//images.trvl-media.com/lodging/1000000/930000/920100/920050/c8a0ec33_y.jpg) ### Portland Regency Hotel & Spa 10/10 Excellent "We were a 3-10 minute from almost everything. " [](https://expedia.co.uk/Portland-Hotels-Portland-Regency-Hotel-Spa.h920050.Hotel-Information) ![Fireside Inn & Suites Portland](//images.trvl-media.com/lodging/1000000/10000/9900/9842/bc09b846_y.jpg) ### Fireside Inn & Suites Portland 10/10 Excellent "Quiet, right off the pike, spacious. Outdated but still decent. " [](https://expedia.co.uk/Portland-Hotels-Fireside-Inn-Suites.h9842.Hotel-Information) ![Portland Harbor Hotel](//images.trvl-media.com/lodging/1000000/900000/898700/898621/83fe4590_y.jpg) ### Portland Harbor Hotel 10/10 Excellent "Perfect!! Clean, friendly , accommodating!! And the restaurant food was delicious!" [](https://expedia.co.uk/Portland-Hotels-Portland-Harbor-Hotel.h898621.Hotel-Information) ![Embassy Suites by Hilton Portland Maine](//images.trvl-media.com/lodging/1000000/20000/14800/14751/cbc24127_y.jpg) ### Embassy Suites by Hilton Portland Maine 10/10 Excellent "Great location. Friendly staff. Highly recommend." [](https://expedia.co.uk/Portland-Hotels-Embassy-Suites-By-Hilton-Portland-Maine.h14751.Hotel-Information) ![Clarion Hotel Portland](//images.trvl-media.com/lodging/1000000/10000/7200/7171/b163ad24_y.jpg) ### Clarion Hotel Portland 10/10 Excellent "I arrived late and haven’t had a chance to see the area yet. Hotel is clean with friendly staff " [](https://expedia.co.uk/Portland-Hotels-Clarion-Hotel-Portland.h7171.Hotel-Information) ![Holiday Inn Portland-By the Bay by IHG](//images.trvl-media.com/lodging/1000000/20000/12000/11991/e922ee9f_y.jpg) ### Holiday Inn Portland-By the Bay by IHG 10/10 Excellent "Early check in." [](https://expedia.co.uk/Portland-Hotels-Holiday-Inn-Portland-By-The-Bay.h11991.Hotel-Information) ![Tru by Hilton Portland Airport Area](//images.trvl-media.com/lodging/19000000/18960000/18952900/18952854/c3cda57d_y.jpg) ### Tru by Hilton Portland Airport Area 10/10 Excellent "Great staff and the gym was awesome to have " [](https://expedia.co.uk/Portland-Hotels-Tru-By-Hilton-Portland-Airport-Area.h18952854.Hotel-Information) ## Frequently asked questions ### How much do business hotels in Casco Bay Islands cost? > Expect to pay between £197 and £197 per night for business hotels in Casco Bay Islands. Terrific deals on properties that cater to work-related travellers as just a click away on Expedia. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### Why book your business hotel in Casco Bay Islands with Expedia? > Here at Expedia, it's our job to help you find the perfect stay at the right price. From 5-star corporate-friendly escapes to affordable motor inns filled with all the amenities you need, you'll have your next work trip organised in a few simple clicks. ### How can I find cheap business hotels in Casco Bay Islands? > Select the "business friendly" filter, located under the "traveller experience" heading, to find cheap business hotels in Casco Bay Islands. Then narrow your search by your per-night budget. 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