Title: The Best Hotels Closest to Main Street Hyannis in Hyannis - 2026 Updated Prices | Expedia.co.uk

[Hyannis Travel Guide](https://expedia.co.uk/Hyannis.dx1544)[Holiday Rentals in Hyannis](https://expedia.co.uk/Hyannis-Holiday-Rentals.d1544.Travel-Guide-HolidayRentals)[Flights to Hyannis](https://expedia.co.uk/Cheap-Flights-To-Hyannis.d1544.Travel-Guide-Flights)[Things to do in Hyannis](https://expedia.co.uk/Things-To-Do-In-Hyannis.d1544.Travel-Guide-Activities)[Main Street Hyannis Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Main-Street-Hyannis.d6287458.Car-Hire-Guide)[Main Street Hyannis Holidays](https://expedia.co.uk/Main-Street-Hyannis-Hyannis.d6287458.Attraction)

![Main Street Hyannis featuring street scenes as well as a couple](https://images.trvl-media.com/place/6287458/f083813a-eac6-4b18-a763-a901fa1ed4e5.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Search Hotels Near Main Street Hyannis, Hyannis

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## Check prices for these dates

Tonight

[4 Dec - 5 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2025-12-04&endDate=2025-12-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[5 Dec - 6 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2025-12-05&endDate=2025-12-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Property class

## Top Trending Hotels Near Main Street Hyannis

![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/7438dff7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/6d244f7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Porch](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/82e4c2e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/0c3650ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Anchor In Distinctive Waterfront Lodging

0.4 mi from Main Street Hyannis

9.4/10

Exceptional

(1006)

"Beautiful quaint hotel, with a nice view of the water. The place has a pool, a fire pit and nice spacious rooms. Would stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alberto

£119

includes taxes & fees

29 Dec - 30 Dec

[](https://www.expedia.co.uk/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information)

![Luxury King Room  | Egyptian cotton sheets, premium bedding, individually decorated](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/c0638e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily full breakfast ](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/03963e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/f8a15f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/07a34c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sea Street Inn

1 mi from Main Street Hyannis

9.8/10

Exceptional

(45)

"Adrian was an awesome host. Comfortable bed, safe area to walk, beautiful surroundings."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jori

£202

includes taxes & fees

2 Jan - 3 Jan 2026

[](https://www.expedia.co.uk/Hyannis-Hotels-Sea-Street-Inn.h26468676.Hotel-Information)

![View from room](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/76dbfadf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/10f6fac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![VISIONARY KING ELITE | Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/82541975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gift shop](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/ff5be5db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Uncommoner Hotel by Reverie Boutique Collection

1.2 mi from Main Street Hyannis

9.4/10

Exceptional

(97)

"Hotel was quiet and very clean , pool water was cool"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robyn

£88

includes taxes & fees

10 Dec - 11 Dec

[](https://www.expedia.co.uk/West-Yarmouth-Hotels-Tidewater-Inn.h480770.Hotel-Information)

![Beach nearby](https://images.trvl-media.com/lodging/1000000/10000/4400/4331/4eacbec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/10000/4400/4331/9771d4ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic Area](https://images.trvl-media.com/lodging/1000000/10000/4400/4331/ceb39eb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4400/4331/561b34ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Cove at Yarmouth by Westgate Resorts

1.3 mi from Main Street Hyannis

9.2/10

Wonderful

(243)

"Great place to stay. Clean, friendly and accommodating!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mike

£92

includes taxes & fees

7 Dec - 8 Dec

[](https://www.expedia.co.uk/West-Yarmouth-Hotels-The-Cove-At-Yarmouth.h4331.Hotel-Information)

![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/dc2c7156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 1 King Bed, Non Smoking | Living area | 37-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/667d7c08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f6ec329c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast ](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f33d73c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Cape Cod-West Yarmouth

1 mi from Main Street Hyannis

8.8/10

Excellent

(1000)

"Excellent stay."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Patricia

£85

includes taxes & fees

22 Dec - 23 Dec

[](https://www.expedia.co.uk/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information)

![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/85f07916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, 2 poolside bars](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/37259fda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 King Bed | Premium bedding, blackout curtains, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/557f1a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/a80381e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bayside Resort Hotel

1.4 mi from Main Street Hyannis

8.8/10

Excellent

(1533)

"Great place..Friday wonderful breakfast, clean as always. Have stayed here 6 timmes Never disappointed "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Donna

£69

includes taxes & fees

1 Jan - 2 Jan 2026

[](https://www.expedia.co.uk/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/ba128f08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/3168dc41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/1a19fbd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/b801373a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard By Marriott Cape Cod Hyannis

1 mi from Main Street Hyannis

8.8/10

Excellent

(485)

"Pretty nice location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Saulius

£94

includes taxes & fees

20 Dec - 21 Dec

[](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-By-Marriott-Cape-Cod-Hyannis.h1517.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/a974137b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/df083265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/8c1d510e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/dd4b8ad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Cape Cod Hyannis

1.4 mi from Main Street Hyannis

8.8/10

Excellent

(652)

"Great people, nice breakfast "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lorri

£87

includes taxes & fees

4 Jan - 5 Jan 2026

[](https://www.expedia.co.uk/Hyannis-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Cod-Hyannis.h7660.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/cddd593a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Two Double Beds | Hypo-allergenic bedding, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/85ee8ddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/2de66a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Doubletree by Hilton Cape Cod - Hyannis

0.6 mi from Main Street Hyannis

8.4/10

Very good

(875)

"Nice room, freindly staff. The downside is the food was pricey. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Steffanie

£93

includes taxes & fees

26 Dec - 27 Dec

[](https://www.expedia.co.uk/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information)

![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/f7a87ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/a26c3d28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/d4c5b048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/b13a9f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn Hyannis - Cape Cod

0.2 mi from Main Street Hyannis

8.0/10

Very good

(1000)

"Karla at the front desk was so welcoming and accommodating."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Megan

£84

includes taxes & fees

18 Dec - 19 Dec

[](https://www.expedia.co.uk/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information)

![Indoor pool](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/5d7ebe6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/e9405833.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/9d421872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/0a9fa15c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard Resort

0.2 mi from Main Street Hyannis

8.0/10

Very good

(39)

"Staff extremely helpful, pleasant. Rooms clean, pool terrific. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

katherine

£93

includes taxes & fees

18 Dec - 19 Dec

[](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/741b5772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/3225f1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/0271fbcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/b017dd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyannis Harbor Hotel

0.4 mi from Main Street Hyannis

8.0/10

Very good

(1010)

"Very clean, staff friendly and all amenities were great!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joao

£126

includes taxes & fees

15 Dec - 16 Dec

[](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/aa954682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/6cc9c6b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds | Internet, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/d3887aa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/efa49ff6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cape Sands Inn

1.2 mi from Main Street Hyannis

8.2/10

Very good

(1016)

"I love this hotel clean good up keep "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jerome

£51

includes taxes & fees

5 Dec - 6 Dec

[](https://www.expedia.co.uk/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/6128ed99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/5c644d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/99f74591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/82916b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Hyannis by IHG

1.8 mi from Main Street Hyannis

8.2/10

Very good

(975)

"Great place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lilian

£97

includes taxes & fees

26 Dec - 27 Dec

[](https://www.expedia.co.uk/Hyannis-Hotels-Holiday-Inn-Hyannis-By-IHG.h12477.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f7fc1d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/ef69e045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/9afdfb4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Plaza Suite | Premium bedding, down duvets, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/34fe26da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyannis Plaza Hotel

0.5 mi from Main Street Hyannis

7.0/10

Good

(964)

"good stay for night"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

£61

includes taxes & fees

2 Jan - 3 Jan 2026

[](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information)

![Family House, Private Bathroom, Pool View | Shared kitchen](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/1de4e978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Private Bathroom, Pool View | Shared kitchen](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/4a3b4c38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Private Bathroom, Pool View](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/fa76fd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Private Bathroom, Pool View | Restaurant](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/6936f2b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sal's Place

1.6 mi from Main Street Hyannis

£330

includes taxes & fees

7 Dec - 8 Dec

[](https://www.expedia.co.uk/Hyannis-Hotels-Sals-Place.h119373964.Hotel-Information)

![Garden](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/00d26354.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/2b1f0d40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 Queen Bed | 1 bedroom, premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/1c660188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/c14b1773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Village Inn Cape Cod

3.8 mi from Main Street Hyannis

10/10

Exceptional

(222)

"It was so charming, would definitely stay there again! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kyle

£145

includes taxes & fees

8 Dec - 9 Dec

[](https://www.expedia.co.uk/Yarmouth-Port-Hotels-The-Village-Inn-Cape-Cod.h12426891.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/37000000/36050000/36043300/36043240/79d06d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/37000000/36050000/36043300/36043240/8cac69f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/37000000/36050000/36043300/36043240/3c6038a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/37000000/36050000/36043300/36043240/6d661bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Inn on Main

4 mi from Main Street Hyannis

10/10

Exceptional

(73)

"We love staying here! Best dog B&B in America!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barbara

£182

includes taxes & fees

8 Dec - 9 Dec

[](https://www.expedia.co.uk/Yarmouth-Port-Hotels-Inn-On-Main.h36043240.Hotel-Information)

![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee shop](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/389ef6aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/0ad12b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b82acf26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Margaritaville Resort Cape Cod

2 mi from Main Street Hyannis

8.8/10

Excellent

(409)

"The entire place was spotless and rooom beet pleasant. Staff was super friendly and the Landshark Bar was excellent. Highly recommend a stay here ! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephen

£139

includes taxes & fees

7 Dec - 8 Dec

[](https://www.expedia.co.uk/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/32aabc06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/5bdfdac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Cottage, 2 Bedrooms, Garden View | Private kitchen | Coffee/tea maker](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/d5121e24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/9440495d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Escape Inn

4.7 mi from Main Street Hyannis

9.4/10

Exceptional

(653)

"One of the best hotels I stayed at "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Robert

£77

includes taxes & fees

6 Dec - 7 Dec

[](https://www.expedia.co.uk/South-Yarmouth-Hotels-The-Escape-Inn.h6697712.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-18&endDate=2025-12-19&regionId=6287458&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top Main Street Hyannis Hotel Reviews

![Hyannis Travel Inn](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/fe11d49f_y.jpg)

### Hyannis Travel Inn

10/10 Excellent

"I love this place! Always amazing time her and the staff is top notch!"

[](https://expedia.co.uk/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information)

![Anchor In Distinctive Waterfront Lodging](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/7438dff7_y.jpg)

### Anchor In Distinctive Waterfront Lodging

10/10 Excellent

"I believe Sandi at the desk gave me the best greeting and welcome I have ever received from a hotel. She wasn't 'corporate' but very personable. She didn't just tell us about the breakfast, the pool, etc...she took us in a small tour to show us. The room where we had breakfast was very homey with a roaring fire in the fireplace. "

[](https://expedia.co.uk/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information)

![Doubletree by Hilton Cape Cod - Hyannis](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314_y.jpg)

### Doubletree by Hilton Cape Cod - Hyannis

10/10 Excellent

"Nice room, freindly staff. The downside is the food was pricey. "

[](https://expedia.co.uk/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information)

![Hampton Inn & Suites Cape Cod-West Yarmouth](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/dc2c7156_y.jpg)

### Hampton Inn & Suites Cape Cod-West Yarmouth

10/10 Excellent

"Large rooms, great amenities. Excellent breakfast. Front desk was very sweet and willing to help and give recommendations. Bartender at the pool was entertaining and kind.overall great experience."

[](https://expedia.co.uk/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information)

![Margaritaville Resort Cape Cod](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f_y.jpg)

### Margaritaville Resort Cape Cod

10/10 Excellent

"The entire place was spotless and rooom beet pleasant. Staff was super friendly and the Landshark Bar was excellent. Highly recommend a stay here ! "

[](https://expedia.co.uk/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information)

![Courtyard Resort](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/5d7ebe6e_y.jpg)

### Courtyard Resort

10/10 Excellent

"The hot tub was hot enough and the room was bright with matching furniture. Great location on Main Street!"

[](https://expedia.co.uk/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information)

![Hyannis Harbor Hotel](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/741b5772_y.jpg)

### Hyannis Harbor Hotel

10/10 Excellent

"Very clean, staff friendly and all amenities were great!"

[](https://expedia.co.uk/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information)

![Cape Sands Inn](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/aa954682_y.jpg)

### Cape Sands Inn

10/10 Excellent

"Clean room, great rate easy checkin and easy checkout. Will stay again. "

[](https://expedia.co.uk/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information)

![Hyannis Plaza Hotel](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f7fc1d07_y.jpg)

### Hyannis Plaza Hotel

10/10 Excellent

"Staff was great and room was very clean "

[](https://expedia.co.uk/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information)

## Hotels near other Main Street Hyannis attractions

![John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts](https://images.trvl-media.com/place/6070185/b92268d1-27eb-4055-a07b-800040c40061.jpg)

### John F. Kennedy Hyannis Museum

4.4/5 (259 reviews)

Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6070185)

![Cape Cod Maritime Museum which includes a bay or harbor and signage](https://images.trvl-media.com/place/553248635146342095/6c8cea24-96a8-41da-86a8-64397b473956.jpg)

### Cape Cod Maritime Museum

You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the seaside in this family-friendly area or visit its seafood restaurants. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635146342095)

![St. Francis Xavier Church featuring signage and a church or cathedral](https://images.trvl-media.com/place/6286986/d75d0252-a6d7-4bb9-9dd9-82f6c06a49ac.jpg)

### St. Francis Xavier Church

4.4/5 (45 reviews)

After visiting St. Francis Xavier Church, make a plan to see the other sights and activities in Hyannis. Wander through the beautiful beaches and waterfront in this family-friendly area. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6286986)

![John F. Kennedy Memorial which includes flowers](https://images.trvl-media.com/place/6286978/9b85082f-75c6-4ae3-ac16-7a3f1c71a2a9.jpg)

### John F. Kennedy Memorial

4.5/5 (110 reviews)

Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial.

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6286978)

### Hyannis Armory

Learn about the local history of Hyannis with a stop at Hyannis Armory. Wander the waterfront and beautiful beaches in the area. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=950930054190297088)

### Hyannis Youth & Community Center

You can take time to visit Hyannis Youth & Community Center during your travels to Hyannis. Stroll along the beautiful beaches or visit the shops in the area. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635976357139)

### Zion Union Heritage Museum

You can spend an afternoon exploring the galleries in Zion Union Heritage Museum during your trip to Hyannis. Make time to visit the area's shops or simply enjoy its seafood restaurants. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=724958852913086464)

### Commotion Charters

Enjoy an outing to Commotion Charters during your stay in Hyannis. Attend a sporting event or simply enjoy the seafood restaurants while you're in the area. 

[See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621532666521)

## Frequently asked questions

### What's the area like around Main Street Hyannis?

### Where is the best place to stay near Main Street Hyannis?

### How many hotels can I expect to find near Main Street Hyannis?

### If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?

### What can I see and do near Main Street Hyannis?