Title: The Best Hotels Closest to Main Street Hyannis in Hyannis - 2026 Updated Prices | Expedia.co.uk [Hyannis Travel Guide](https://expedia.co.uk/Hyannis.dx1544)[Holiday Rentals in Hyannis](https://expedia.co.uk/Hyannis-Holiday-Rentals.d1544.Travel-Guide-HolidayRentals)[Flights to Hyannis](https://expedia.co.uk/Cheap-Flights-To-Hyannis.d1544.Travel-Guide-Flights)[Things to do in Hyannis](https://expedia.co.uk/Things-To-Do-In-Hyannis.d1544.Travel-Guide-Activities)[Main Street Hyannis Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Main-Street-Hyannis.d6287458.Car-Hire-Guide)[Main Street Hyannis Holidays](https://expedia.co.uk/Main-Street-Hyannis-Hyannis.d6287458.Attraction) ![Main Street Hyannis featuring street scenes as well as a couple](https://images.trvl-media.com/place/6287458/f083813a-eac6-4b18-a763-a901fa1ed4e5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels Near Main Street Hyannis, Hyannis - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [20 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2025-12-20&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [21 Dec - 22 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2025-12-21&endDate=2025-12-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Main Street Hyannis hotels ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/7438dff7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/6d244f7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 2 Queen Beds, Harbour View | Living area | 55-inch Smart TV with cable channels, Netflix, Hulu](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/c85afb09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/0c3650ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anchor In Distinctive Waterfront Lodging [](https://www.expedia.co.uk/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information) 0.4 mi from Main Street Hyannis 9.4/10 Exceptional (1000) "Staff member Sandy very congenial when we checked in. Laid back atmosphere (early December). Will consider for future Hyannis stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lawrence £141 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/76dbfadf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/10f6fac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![VISIONARY KING ELITE | Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/82541975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/75730e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uncommoner Hotel by Reverie Boutique Collection [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Tidewater-Inn.h480770.Hotel-Information) 1.2 mi from Main Street Hyannis 9.4/10 Exceptional (97) "Hotel was quiet and very clean , pool water was cool" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robyn £91 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Tidewater-Inn.h480770.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/85f07916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed | Premium bedding, blackout curtains, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/557f1a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/85a6d03d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, 2 poolside bars](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/37259fda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bayside Resort Hotel [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information) 1.4 mi from Main Street Hyannis 8.8/10 Excellent (1523) "Reception staff was warm and welcoming! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Liza [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/dc2c7156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/b2eb67f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f33d73c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f6ec329c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Cape Cod-West Yarmouth [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information) 1 mi from Main Street Hyannis 8.8/10 Excellent (1001) "Excellent stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patricia £97 includes taxes & fees 13 Jan - 14 Jan 2026 [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/a974137b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/8c1d510e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/9db04da3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/df083265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Cod Hyannis [](https://www.expedia.co.uk/Hyannis-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Cod-Hyannis.h7660.Hotel-Information) 1.4 mi from Main Street Hyannis 8.8/10 Excellent (661) "Excellent staff-clean rooms-great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patrice £94 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/Hyannis-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Cod-Hyannis.h7660.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/ba128f08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/85e7753a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/3168dc41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/1a19fbd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard By Marriott Cape Cod Hyannis [](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-By-Marriott-Cape-Cod-Hyannis.h1517.Hotel-Information) 1 mi from Main Street Hyannis 8.8/10 Excellent (486) "Pretty nice location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Saulius £105 includes taxes & fees 19 Jan - 20 Jan 2026 [](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-By-Marriott-Cape-Cod-Hyannis.h1517.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/ce103da5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two Double Beds | Hypo-allergenic bedding, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/85ee8ddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/cddd593a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Cape Cod - Hyannis [](https://www.expedia.co.uk/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) 0.6 mi from Main Street Hyannis 8.4/10 Very good (878) "Nice room, freindly staff. The downside is the food was pricey. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steffanie £98 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/aa954682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/efa49ff6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/3bffd99c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds | Internet, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/d3887aa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cape Sands Inn [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information) 1.2 mi from Main Street Hyannis 8.2/10 Very good (1016) "Clean room courteous staff and easy check in " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda £64 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/6128ed99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/99f74591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/82916b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/5c644d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Hyannis by IHG [](https://www.expedia.co.uk/Hyannis-Hotels-Holiday-Inn-Hyannis-By-IHG.h12477.Hotel-Information) 1.8 mi from Main Street Hyannis 8.2/10 Very good (977) "Check in was easy and the front desk person was wonderful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anastasios £82 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Hyannis-Hotels-Holiday-Inn-Hyannis-By-IHG.h12477.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/f7a87ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/d4c5b048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/0231de53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/a26c3d28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Hyannis - Cape Cod [](https://www.expedia.co.uk/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information) 0.2 mi from Main Street Hyannis 8.0/10 Very good (1004) "Nice hotel had a perfect stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £84 includes taxes & fees 26 Dec - 27 Dec [](https://www.expedia.co.uk/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/741b5772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/35291799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/0271fbcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/b017dd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyannis Harbor Hotel [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) 0.4 mi from Main Street Hyannis 8.0/10 Very good (1000) "Amazing place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mounir £124 includes taxes & fees 30 Dec - 31 Dec [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f7fc1d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/9afdfb4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/786ccd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/ef69e045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyannis Plaza Hotel [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information) 0.5 mi from Main Street Hyannis 7.0/10 Good (970) "good stay for night" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £67 includes taxes & fees 18 Jan - 19 Jan 2026 [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information) ![Luxury King Room | Egyptian cotton sheets, premium bedding, individually decorated](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/c0638e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/b45ea86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/03963e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/07a34c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Street Inn [](https://www.expedia.co.uk/Hyannis-Hotels-Sea-Street-Inn.h26468676.Hotel-Information) 1 mi from Main Street Hyannis 9.8/10 Exceptional (45) "Adrian was an awesome host. Comfortable bed, safe area to walk, beautiful surroundings." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jori £202 includes taxes & fees 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/Hyannis-Hotels-Sea-Street-Inn.h26468676.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/5d7ebe6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/e9405833.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/e4d68938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/9d421872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Resort [](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information) 0.2 mi from Main Street Hyannis 8.2/10 Very good (46) "Clean and inexpensive" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £93 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information) ![Family House, Private Bathroom, Pool View | Shared kitchen](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/1de4e978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Private Bathroom, Pool View](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/fa76fd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Private Bathroom, Pool View | Terrace/patio](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/4ede3fc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, Private Bathroom, Pool View | Restaurant](https://images.trvl-media.com/lodging/120000000/119380000/119374000/119373964/6936f2b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sal's Place [](https://www.expedia.co.uk/Hyannis-Hotels-Sals-Place.h119373964.Hotel-Information) 1.6 mi from Main Street Hyannis £329 includes taxes & fees 30 Dec - 31 Dec [](https://www.expedia.co.uk/Hyannis-Hotels-Sals-Place.h119373964.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/00d26354.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/c14b1773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/2b1f0d40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed | 1 bedroom, premium bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/13000000/12430000/12426900/12426891/1c660188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Village Inn Cape Cod [](https://www.expedia.co.uk/Yarmouth-Port-Hotels-The-Village-Inn-Cape-Cod.h12426891.Hotel-Information) 3.8 mi from Main Street Hyannis 10/10 Exceptional (223) "It was so charming, would definitely stay there again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kyle £145 includes taxes & fees 27 Dec - 28 Dec [](https://www.expedia.co.uk/Yarmouth-Port-Hotels-The-Village-Inn-Cape-Cod.h12426891.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1160000/1159200/1159118/c2ed8a3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Room, Private Bathroom (Bayberry Room) | Premium bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/2000000/1160000/1159200/1159118/5a3acb10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1160000/1159200/1159118/3b0ad9d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1159200/1159118/54fdf702.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Brewster by the Sea Inn [](https://www.expedia.co.uk/Brewster-Hotels-Brewster-By-The-Sea-Inn.h1159118.Hotel-Information) 10.8 mi from Main Street Hyannis 9.8/10 Exceptional (171) "Brewster By the Sea has it all - great location, amazing innkeeper, unbelievable breakfasts, and great rooms with perfect amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna £272 includes taxes & fees 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/Brewster-Hotels-Brewster-By-The-Sea-Inn.h1159118.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/32aabc06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/5bdfdac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/9440495d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Cottage, 2 Bedrooms, Garden View | Private kitchen | Coffee/tea maker](https://images.trvl-media.com/lodging/7000000/6700000/6697800/6697712/d5121e24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Escape Inn [](https://www.expedia.co.uk/South-Yarmouth-Hotels-The-Escape-Inn.h6697712.Hotel-Information) 4.7 mi from Main Street Hyannis 9.4/10 Exceptional (656) "clean, convenient and very easy check in/out. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) chris £69 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/South-Yarmouth-Hotels-The-Escape-Inn.h6697712.Hotel-Information) ![Gazebo](https://images.trvl-media.com/lodging/2000000/1190000/1181400/1181333/cf5e1161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 7:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/2000000/1190000/1181400/1181333/3101fb8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/2000000/1190000/1181400/1181333/c530c2ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1190000/1181400/1181333/082cb655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Veranda Cape Cod Family Resort [](https://www.expedia.co.uk/South-Yarmouth-Hotels-Veranda-Cape-Cod-Family-Resort.h1181333.Hotel-Information) 4.8 mi from Main Street Hyannis 9.2/10 Wonderful (262) "Beautiful grounds, quiet and comfortable. Very well run. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Benita £153 includes taxes & fees 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/South-Yarmouth-Hotels-Veranda-Cape-Cod-Family-Resort.h1181333.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b82acf26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/0ad12b76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/e05c3d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Margaritaville Resort Cape Cod [](https://www.expedia.co.uk/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) 2 mi from Main Street Hyannis 8.8/10 Excellent (415) "The entire place was spotless and rooom beet pleasant. Staff was super friendly and the Landshark Bar was excellent. Highly recommend a stay here ! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen £163 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-03&endDate=2026-01-04®ionId=6287458&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Main Street Hyannis Hotel Reviews ![Bayside Resort Hotel](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/85f07916_y.jpg) ### Bayside Resort Hotel 10/10 Excellent "Reception staff was warm and welcoming! " [](https://expedia.co.uk/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information) ![Courtyard Resort](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/5d7ebe6e_y.jpg) ### Courtyard Resort 10/10 Excellent "Clean rooms, full kitchens, good area. " [](https://expedia.co.uk/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information) ![Hyannis Harbor Hotel](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/741b5772_y.jpg) ### Hyannis Harbor Hotel 10/10 Excellent "I’ve been to this hotel before. Its lovely." [](https://expedia.co.uk/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) ![Comfort Inn Hyannis - Cape Cod](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/f7a87ca8_y.jpg) ### Comfort Inn Hyannis - Cape Cod 10/10 Excellent "Nice hotel had a perfect stay" [](https://expedia.co.uk/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information) ![Margaritaville Resort Cape Cod](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f_y.jpg) ### Margaritaville Resort Cape Cod 10/10 Excellent "An amazing stay, very clean, friendly staff and the ease of getting around. " [](https://expedia.co.uk/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) ![Anchor In Distinctive Waterfront Lodging](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/7438dff7_y.jpg) ### Anchor In Distinctive Waterfront Lodging 10/10 Excellent "Very nice place to stay!! Mary, (at the desk) was very kind and hospitable. " [](https://expedia.co.uk/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information) ![Cape Sands Inn](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/aa954682_y.jpg) ### Cape Sands Inn 10/10 Excellent "Clean room courteous staff and easy check in " [](https://expedia.co.uk/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information) ![Doubletree by Hilton Cape Cod - Hyannis](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314_y.jpg) ### Doubletree by Hilton Cape Cod - Hyannis 10/10 Excellent "Everything was great . One comforter on the bed was a little dirty. We liked everything else." [](https://expedia.co.uk/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) ![Hyannis Travel Inn](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/fe11d49f_y.jpg) ### Hyannis Travel Inn 10/10 Excellent "Very kind staff. Functional, clean room. Had an early bus and they let me take a few things for breakfast the night before." [](https://expedia.co.uk/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information) ## Hotels near other Main Street Hyannis attractions ![John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts](https://images.trvl-media.com/place/6070185/b92268d1-27eb-4055-a07b-800040c40061.jpg) ### John F. Kennedy Hyannis Museum 4.4/5 (259 reviews) Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6070185) ![Cape Cod Maritime Museum which includes a bay or harbor and signage](https://images.trvl-media.com/place/553248635146342095/6c8cea24-96a8-41da-86a8-64397b473956.jpg) ### Cape Cod Maritime Museum You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the beautiful beaches in this family-friendly area or visit its seafood restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635146342095) ![St. Francis Xavier Church featuring signage and a church or cathedral](https://images.trvl-media.com/place/6286986/d75d0252-a6d7-4bb9-9dd9-82f6c06a49ac.jpg) ### St. Francis Xavier Church 4.4/5 (45 reviews) After visiting St. Francis Xavier Church, make a plan to see the other sights and activities in Hyannis. Wander through the beautiful beaches and waterfront in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6286986) ![John F. Kennedy Memorial which includes flowers](https://images.trvl-media.com/place/6286978/9b85082f-75c6-4ae3-ac16-7a3f1c71a2a9.jpg) ### John F. Kennedy Memorial 4.5/5 (110 reviews) Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6286978) ### Hyannis Armory Learn about the local history of Hyannis with a stop at Hyannis Armory. Wander the waterfront and beautiful beaches in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950930054190297088) ### Hyannis Youth & Community Center You can take time to visit Hyannis Youth & Community Center during your travels to Hyannis. Stroll along the waterfront or visit the shops in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635976357139) ### Zion Union Heritage Museum You can spend an afternoon exploring the galleries in Zion Union Heritage Museum during your trip to Hyannis. Make time to visit the area's shops or simply enjoy its seafood restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=724958852913086464) ### Commotion Charters Enjoy an outing to Commotion Charters during your stay in Hyannis. Attend a sporting event or simply enjoy the seafood restaurants while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532666521) ## Frequently asked questions ### What's the area like around Main Street Hyannis? ### Where is the best place to stay near Main Street Hyannis? ### How many hotels can I expect to find near Main Street Hyannis? ### If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund? ### What can I see and do near Main Street Hyannis?