Title: The Best Hotels Closest to Main Street Hyannis in Hyannis - 2025 Updated Prices | Expedia.co.uk [Hyannis Travel Guide](https://expedia.co.uk/Hyannis.dx1544)[Holiday Rentals in Hyannis](https://expedia.co.uk/Hyannis-Holiday-Rentals.d1544.Travel-Guide-HolidayRentals)[Flights to Hyannis](https://expedia.co.uk/Cheap-Flights-To-Hyannis.d1544.Travel-Guide-Flights)[Things to do in Hyannis](https://expedia.co.uk/Things-To-Do-In-Hyannis.d1544.Travel-Guide-Activities)[Main Street Hyannis Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Main-Street-Hyannis.d6287458.Car-Hire-Guide)[Main Street Hyannis Holidays](https://expedia.co.uk/Main-Street-Hyannis-Hyannis.d6287458.Attraction) ![Main Street Hyannis featuring street scenes as well as a couple](https://images.trvl-media.com/place/6287458/f083813a-eac6-4b18-a763-a901fa1ed4e5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels Near Main Street Hyannis, Hyannis - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [4 Nov - 5 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2025-11-04&endDate=2025-11-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [5 Nov - 6 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2025-11-05&endDate=2025-11-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Top Trending Hotels Near Main Street Hyannis ![Exterior](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/fe11d49f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/3ac160a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/91996a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, Multiple Beds | Iron/ironing board, cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/2c353cdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyannis Travel Inn 0.1 mi from Main Street Hyannis 9.6/10 Exceptional (1009) "Very pleased with clean & tidy accommodations" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) patricia £81 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/7438dff7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/82e4c2e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/0c3650ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 2 Queen Beds, Harbour View | Living area | 55-inch Smart TV with cable channels, Netflix, Hulu](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/c85afb09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anchor In Distinctive Waterfront Lodging 0.4 mi from Main Street Hyannis 9.4/10 Exceptional (1018) "Great place to stay! Will be back." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colleen £161 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information) ![Luxury King Room | Egyptian cotton sheets, premium bedding, individually decorated](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/c0638e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/03963e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/07a34c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/b45ea86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Street Inn 1 mi from Main Street Hyannis 9.8/10 Exceptional (45) "Very nicely renovated small property with a fantastic breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul £215 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Hyannis-Hotels-Sea-Street-Inn.h26468676.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/76dbfadf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/10f6fac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/ff5be5db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![VISIONARY KING ELITE | Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/82541975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uncommoner Hotel by Reverie Boutique Collection 1.2 mi from Main Street Hyannis 9.4/10 Exceptional (83) "Great staff, beautiful property" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Margaret £110 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Tidewater-Inn.h480770.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/dc2c7156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Non Smoking | Living area | 37-inch LCD TV with satellite channels, TV](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/667d7c08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f33d73c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f6ec329c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Cape Cod-West Yarmouth 1 mi from Main Street Hyannis 8.8/10 Excellent (1004) "good location and overall value." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chester £93 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/ba128f08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/85e7753a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/1a19fbd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/3168dc41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard By Marriott Cape Cod Hyannis 1 mi from Main Street Hyannis 8.8/10 Excellent (481) "Pretty nice location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Saulius £106 includes taxes & fees 19 Nov - 20 Nov [](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-By-Marriott-Cape-Cod-Hyannis.h1517.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/85f07916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/85a6d03d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, pub, pub](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/37259fda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/a80381e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bayside Resort Hotel 1.4 mi from Main Street Hyannis 8.8/10 Excellent (1524) "Great spot for families, indoor pool was wonderful and arcade, fire pit and good breakfast options." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kaitlyn [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/a974137b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/df083265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/8c1d510e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/9db04da3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Cod Hyannis 1.4 mi from Main Street Hyannis 8.8/10 Excellent (631) "Great people, nice breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorri £88 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Hyannis-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Cod-Hyannis.h7660.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/2de66a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/ce103da5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two Double Beds | Hypo-allergenic bedding, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/85ee8ddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Cape Cod - Hyannis 0.6 mi from Main Street Hyannis 8.4/10 Very good (867) "Doubletree as expected" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carmen £101 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/f7a87ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/d4c5b048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/b13a9f06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/a26c3d28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Hyannis - Cape Cod 0.2 mi from Main Street Hyannis 8.0/10 Very good (1001) "Their continental breakfast had more options than other hotels I’ve booked! Loved the breakfast choices! We enjoyed the food and our stay. Cozy and clean beds and our room ac worked perfectly! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terina £85 includes taxes & fees 10 Nov - 11 Nov [](https://www.expedia.co.uk/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/741b5772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/b017dd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/35291799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/3225f1fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyannis Harbor Hotel 0.4 mi from Main Street Hyannis 8.0/10 Very good (1033) "This property was perfect for our fall weekend visit. We're looking forward to staying during the summer when the Bluewater Grill is open!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer £132 includes taxes & fees 10 Nov - 11 Nov [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/5d7ebe6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/0a9fa15c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/9d421872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/e9405833.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Resort 0.2 mi from Main Street Hyannis 7.8/10 Good (36) "Staff extremely helpful, pleasant. Rooms clean, pool terrific. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) katherine £79 includes taxes & fees 15 Nov - 16 Nov [](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/aa954682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds | Internet, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/d3887aa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/6cc9c6b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/3bffd99c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cape Sands Inn 1.2 mi from Main Street Hyannis 8.2/10 Very good (1007) "I love this hotel clean good up keep " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerome £67 includes taxes & fees 14 Nov - 15 Nov [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/6128ed99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, hypo-allergenic bedding, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/82916b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/5c644d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/c18bcef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Hyannis by IHG 1.8 mi from Main Street Hyannis 8.2/10 Very good (965) "For the price it was perfect for an overnight stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dana £85 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Hyannis-Hotels-Holiday-Inn-Hyannis-By-IHG.h12477.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1560000/1556000/1555968/719ceca4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1560000/1556000/1555968/5ba979da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Cottage, Multiple Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/2000000/1560000/1556000/1555968/f3e77f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1560000/1556000/1555968/f458ac0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Breeze Inn 1.1 mi from Main Street Hyannis 7.8/10 Good (193) "Nice place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin £69 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Hyannis-Hotels-Sea-Breeze-Inn.h1555968.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f7fc1d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/9afdfb4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/ef69e045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/786ccd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyannis Plaza Hotel 0.5 mi from Main Street Hyannis 7.0/10 Good (947) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mirza £65 includes taxes & fees 3 Dec - 4 Dec [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/ef8e0c34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/103e9cdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/929a854e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | Hypo-allergenic bedding, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/c720208e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area 1 mi from Main Street Hyannis 7.0/10 Good (1011) "lots of things nearby easy to get to where you wanted to be " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) june £65 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Days-Inn-By-Wyndham-West-YarmouthHyannis-Cape-Cod-Area.h895210.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/200000/195100/195057/85163ba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/200000/195100/195057/bdfba585.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/200000/195100/195057/9ef6b148.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Single Room | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/200000/195100/195057/98fc4f33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relax Inn Cape Cod 0.9 mi from Main Street Hyannis 6.4/10 (750) "ok for the price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joe £62 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Relax-Inn-Cape-Cod.h195057.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/8200/8135/53ed8649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/8200/8135/ed873d9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/1000000/10000/8200/8135/e89b1ba0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed, Golf View | View from room](https://images.trvl-media.com/lodging/1000000/10000/8200/8135/1d638eab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cape Cod Irish Village 0.9 mi from Main Street Hyannis 6.4/10 (1010) "Plenty of parking space, walking distance to shops & restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) FLOR £91 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Hyannis-Hotels-Resort-Conference-Center-At-Hyannis.h8135.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/540000/533000/532969/9bb322af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/533000/532969/ac9508eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/540000/533000/532969/6a90b735.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/540000/533000/532969/3b60e727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge by Choice - Cape Cod 0.9 mi from Main Street Hyannis 6.2/10 (504) "This was a nice stay for two nights, clean and pet friendly I had my husky dog with me. Only 20 minute walk to the Hyannis ferry was able to leave my car at hotel parking lot for the day and walk on over with my dog to the ferry very easy and convenient! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Camille £69 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Econo-Lodge.h532969.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19®ionId=6287458&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Main Street Hyannis Hotel Reviews ![Courtyard Resort](//images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/5d7ebe6e_y.jpg) ### Courtyard Resort 10/10 Excellent "Great stay staff was awesome. The room was clean and reasonably priced!" [](https://expedia.co.uk/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information) ![Cape Sands Inn](//images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/aa954682_y.jpg) ### Cape Sands Inn 10/10 Excellent "Very clean and really appreciated the "quiet hours". The only thing I could suggest is that for the downstairs rooms on the ends, maybe put a small curtain in the bathrooms. It wasn't an issue but if someone wax on the porch upstairs they can look directly down into the bathroom. " [](https://expedia.co.uk/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information) ![Hyannis Travel Inn](//images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/fe11d49f_y.jpg) ### Hyannis Travel Inn 10/10 Excellent "The room was beautiful. The staff offered a cot for my son, which was amazing. I didn’t have to ask, and usually don’t ask for. We stayed at another hotel last year for three times the amount per night and that room was literally falling apart. My son definitely e joyed the pool. The entire staff was great! Will definitely stay again if traveling to Cape Cod. " [](https://expedia.co.uk/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information) ![Hampton Inn & Suites Cape Cod-West Yarmouth](//images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/dc2c7156_y.jpg) ### Hampton Inn & Suites Cape Cod-West Yarmouth 10/10 Excellent "Great breakfast with lots ofoptions" [](https://expedia.co.uk/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information) ![SeaCoast Inn](//images.trvl-media.com/lodging/10000000/9410000/9400300/9400206/90-92aafafd_y.jpg) ### SeaCoast Inn 10/10 Excellent "Parking was good and convenient and close to bars and restaurants " [](https://expedia.co.uk/Hyannis-Hotels-SeaCoast-Inn.h9400206.Hotel-Information) ![Hyannis Plaza Hotel](//images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f7fc1d07_y.jpg) ### Hyannis Plaza Hotel 10/10 Excellent "S" [](https://expedia.co.uk/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information) ![Anchor In Distinctive Waterfront Lodging](//images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/7438dff7_y.jpg) ### Anchor In Distinctive Waterfront Lodging 10/10 Excellent "The room was extremely clean, and the balcony has some of the best views of Hyannis harbor there are. The staff is very friendly and helpful I will definitely be staying here again and recommend it to everyone!" [](https://expedia.co.uk/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information) ![Cape Cod Harbor House Inn](//images.trvl-media.com/lodging/12000000/11460000/11451900/11451805/91347598_y.jpg) ### Cape Cod Harbor House Inn 10/10 Excellent "Room was clean. Always nice to have a fridge for insulin. Checkin was easy, pleasant, helpful." [](https://expedia.co.uk/Hyannis-Hotels-Cape-Cod-Harbor-House-Inn.h11451805.Hotel-Information) ![Hyannis Harbor Hotel](//images.trvl-media.com/lodging/1000000/60000/55000/54945/741b5772_y.jpg) ### Hyannis Harbor Hotel 10/10 Excellent "Clean room. Location. " [](https://expedia.co.uk/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) ## Hotels near other Main Street Hyannis attractions [](https://www.expedia.co.uk/John-F-Kennedy-Hyannis-Museum-Hotels.0-l6070185-0.Travel-Guide-Filter-Hotels) ![John F. Kennedy Hyannis Museum showing a statue or sculpture](https://images.trvl-media.com/place/6070185/7e9e6a58-eb55-48ff-bc35-a3283de6db0c.jpg) ### John F. Kennedy Hyannis Museum 4.4/5 (259 reviews) Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6070185) [](https://www.expedia.co.uk/Cape-Cod-Maritime-Museum-Hotels.0-l553248635146342095-0.Travel-Guide-Filter-Hotels) ![Hyannis](https://images.trvl-media.com/place/553248635146342095/f4f9f2be-5681-4d82-8f2a-a01d46fc93fc.jpg) ### Cape Cod Maritime Museum You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the seaside in this family-friendly area or visit its seafood restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635146342095) [](https://www.expedia.co.uk/St-Francis-Xavier-Church-Hotels.0-l6286986-0.Travel-Guide-Filter-Hotels) ![Hyannis](https://images.trvl-media.com/place/6286986/68f1113f-193c-4991-a964-5912a97a8e48.jpg) ### St. Francis Xavier Church 4.4/5 (45 reviews) After visiting St. Francis Xavier Church, make a plan to see the other sights and activities in Hyannis. Wander through the beautiful beaches and waterfront in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6286986) [](https://www.expedia.co.uk/John-F-Kennedy-Memorial-Hotels.0-l6286978-0.Travel-Guide-Filter-Hotels) ![John F. Kennedy Memorial which includes flowers](https://images.trvl-media.com/place/6286978/9b85082f-75c6-4ae3-ac16-7a3f1c71a2a9.jpg) ### John F. Kennedy Memorial 4.5/5 (110 reviews) Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6286978) [](https://www.expedia.co.uk/Hyannis-Armory-Hotels.0-l950930054190297088-0.Travel-Guide-Filter-Hotels) ### Hyannis Armory Learn about the local history of Hyannis with a stop at Hyannis Armory. Wander the waterfront and beautiful beaches in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950930054190297088) [](https://www.expedia.co.uk/Hyannis-Youth-Community-Center-Hotels.0-l553248635976357139-0.Travel-Guide-Filter-Hotels) ### Hyannis Youth & Community Center You can take time to visit Hyannis Youth & Community Center during your travels to Hyannis. Stroll along the beautiful beaches or visit the shops in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635976357139) [](https://www.expedia.co.uk/Zion-Union-Heritage-Museum-Hotels.0-l724958852913086464-0.Travel-Guide-Filter-Hotels) ### Zion Union Heritage Museum You can spend an afternoon exploring the galleries in Zion Union Heritage Museum during your trip to Hyannis. Make time to visit the area's shops or simply enjoy its seafood restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=724958852913086464) [](https://www.expedia.co.uk/Commotion-Charters-Hotels.0-l553248621532666521-0.Travel-Guide-Filter-Hotels) ### Commotion Charters Enjoy an outing to Commotion Charters during your stay in Hyannis. Attend a sporting event or simply enjoy the seafood restaurants while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532666521) ## Frequently asked questions ### What's the area like around Main Street Hyannis? > Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 179 hotels and other accommodation options you'll find within a mile. ### Where is the best place to stay near Main Street Hyannis? > Adjacent to Main Street Hyannis, [Hyannis Travel Inn](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information) is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include [Hyannis Harbor Hotel](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) and [Hyannis Plaza Hotel](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information). ### How many hotels can I expect to find near Main Street Hyannis? > Expedia has 179 hotels and other accommodation options within a mile from Main Street Hyannis. ### If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund? > Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis. ### What can I see and do near Main Street Hyannis? > John F. Kennedy Hyannis Museum, Cape Cod Maritime Museum and Whydah Pirate Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and Sandy Neck Lighthouse are landmarks that you won't want to miss. You can enjoy live performances at Cape Cod Melody Tent and Barnstable Performing Arts Center.