Title: The Best Hotels Closest to Main Street Hyannis in Hyannis - 2026 Updated Prices | Expedia.co.uk [Hyannis Travel Guide](https://expedia.co.uk/Hyannis.dx1544)[Holiday Rentals in Hyannis](https://expedia.co.uk/Hyannis-Holiday-Rentals.d1544.Travel-Guide-HolidayRentals)[Flights to Hyannis](https://expedia.co.uk/Cheap-Flights-To-Hyannis.d1544.Travel-Guide-Flights)[Things to do in Hyannis](https://expedia.co.uk/Things-To-Do-In-Hyannis.d1544.Travel-Guide-Activities)[Main Street Hyannis Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Main-Street-Hyannis.d6287458.Car-Hire-Guide)[Main Street Hyannis Holidays](https://expedia.co.uk/Main-Street-Hyannis-Hyannis.d6287458.Attraction) ![Main Street Hyannis featuring street scenes as well as a couple](https://images.trvl-media.com/place/6287458/f083813a-eac6-4b18-a763-a901fa1ed4e5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6287458/f083813a-eac6-4b18-a763-a901fa1ed4e5.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [20 Mar - 21 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2026-03-20&endDate=2026-03-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [21 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2026-03-21&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [20 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6287458&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Main Street Hyannis hotels ![Restaurant](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/5a8499c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/01ecbf0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/3ac160a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, Multiple Beds | Iron/ironing board, cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/2c353cdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyannis Travel Inn [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information) 0.1 mi from Main Street Hyannis 9.6/10 Exceptional (1,000 reviews) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shane and Jessica £67 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/87d9418f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 Queen Beds Harborview Suite | Living area | 55-inch Smart TV with cable channels, Netflix, Hulu](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/c85afb09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/bfb8a032.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/3fdd0247.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anchor In Distinctive Waterfront Lodging [](https://www.expedia.co.uk/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information) 0.4 mi from Main Street Hyannis 9.4/10 Exceptional (1,000 reviews) "Staff that checked me in was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £128 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/c6220c50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury King Room | Egyptian cotton sheets, premium bedding, individually decorated](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/b6099d08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/f8a15f92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/b45ea86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Street Inn [](https://www.expedia.co.uk/Hyannis-Hotels-Sea-Street-Inn.h26468676.Hotel-Information) 1 mi from Main Street Hyannis 9.8/10 Exceptional (45 reviews) "Very nicely renovated small property with a fantastic breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul £225 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Hyannis-Hotels-Sea-Street-Inn.h26468676.Hotel-Information) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/056f2544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/10f6fac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Voyager Escape King Elite | Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/c366b6b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bicycling](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/6ac8a051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uncommoner Hotel by Reverie Boutique Collection [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Tidewater-Inn.h480770.Hotel-Information) 1.2 mi from Main Street Hyannis 9.2/10 Wonderful (119 reviews) "Clean room, extremely comfortable beds!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Emily M £104 includes taxes & fees 21 Mar - 22 Mar [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Tidewater-Inn.h480770.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/dc2c7156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Studio Whirlpool Non Smoking | Premium bedding, down duvets, in-room safe, blackout curtains](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/040fea3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f6ec329c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/f33d73c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Cape Cod-West Yarmouth [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information) 1 mi from Main Street Hyannis 8.8/10 Excellent (1,000 reviews) "The hotel was very clean and the accommodations exceeded out expectations." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £104 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Hampton-Inn-Suites-Cape-Cod-West-Yarmouth.h2558618.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/3168dc41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/1a19fbd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/85e7753a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![American cuisine](https://images.trvl-media.com/lodging/1000000/10000/1600/1517/4d737673.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard By Marriott Cape Cod Hyannis [](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-By-Marriott-Cape-Cod-Hyannis.h1517.Hotel-Information) 1 mi from Main Street Hyannis 8.8/10 Excellent (495 reviews) "Parking was free and easy, room was very clean and housekeeping service was top notch. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maureen £124 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-By-Marriott-Cape-Cod-Hyannis.h1517.Hotel-Information) ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/783b5af0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/963d562c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Bay View | Premium bedding, blackout curtains, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/d77a27ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/146eb322.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bayside Resort Hotel [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information) 1.4 mi from Main Street Hyannis 8.8/10 Excellent (1,550 reviews) "Great family friendly hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle £105 includes taxes & fees 24 Mar - 25 Mar [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/65000000/64650000/64648900/64648858/2466c5ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/65000000/64650000/64648900/64648858/97e35811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/65000000/64650000/64648900/64648858/f71df5cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/65000000/64650000/64648900/64648858/185d7742.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage House Inn on Cape Cod, an Ascend Collection Hotel [](https://www.expedia.co.uk/Hyannis-Hotels-Heritage-House-Inn.h64648858.Hotel-Information) 0.2 mi from Main Street Hyannis 8.4/10 Very good (20 reviews) "It was ok staff was nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Troy £101 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Hyannis-Hotels-Heritage-House-Inn.h64648858.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/df083265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/08564f33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/dd4b8ad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/7700/7660/a974137b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Cod Hyannis [](https://www.expedia.co.uk/Hyannis-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Cod-Hyannis.h7660.Hotel-Information) 1.4 mi from Main Street Hyannis 8.8/10 Excellent (683 reviews) "Rooms were clean, the beds were comfortable, and the breakfast was good. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sheila £107 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Hyannis-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Cod-Hyannis.h7660.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/5e37150d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/dbd19b42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/e8d49199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Doubletree by Hilton Cape Cod - Hyannis [](https://www.expedia.co.uk/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) 0.6 mi from Main Street Hyannis 8.4/10 Very good (894 reviews) "It was a decent stay I can’t complain " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rony £107 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/5d7ebe6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/e9405833.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/9d421872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/e4d68938.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Resort [](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information) 0.2 mi from Main Street Hyannis 8.2/10 Very good (67 reviews) "The room was clean had everything in it you could need. The staff was friendly and accommodating ice machine easily accessible and a filtered water cooler in the lobby was great. Pool area was closed but it looked like a nice area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marilyn £93 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/b37d6e5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/a26c3d28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/0874e47d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/d4c5b048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Hyannis - Cape Cod [](https://www.expedia.co.uk/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information) 0.2 mi from Main Street Hyannis 8.0/10 Very good (1,001 reviews) "It was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Magdala £88 includes taxes & fees 31 Mar - 1 Apr [](https://www.expedia.co.uk/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/0271fbcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/w6720h4476x0y4-c8befbe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/67eeb1a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/03465c0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyannis Harbor Hotel [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) 0.4 mi from Main Street Hyannis 8.0/10 Very good (1,002 reviews) "Clean room, helpful front desk." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mara £124 includes taxes & fees 23 Mar - 24 Mar [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/3bffd99c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/906db676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Internet, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/bbed7ace.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1340000/1330200/1330174/6cc9c6b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cape Sands Inn [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information) 1.2 mi from Main Street Hyannis 8.2/10 Very good (1,025 reviews) "Clean room, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dennis £64 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Cape-Sands-Inn.h1330174.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/6128ed99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/c18bcef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/0fe4f63e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/1000000/20000/12500/12477/3ec44c1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Hyannis by IHG [](https://www.expedia.co.uk/Hyannis-Hotels-Holiday-Inn-Hyannis-By-IHG.h12477.Hotel-Information) 1.8 mi from Main Street Hyannis 8.2/10 Very good (1,001 reviews) "Pool was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colleen £97 includes taxes & fees 25 Mar - 26 Mar [](https://www.expedia.co.uk/Hyannis-Hotels-Holiday-Inn-Hyannis-By-IHG.h12477.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/10000000/9720000/9717400/9717349/56fb3cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9720000/9717400/9717349/da15317d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self-parking](https://images.trvl-media.com/lodging/10000000/9720000/9717400/9717349/b1131e73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9720000/9717400/9717349/b7b0921f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyannis Host Inn [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Host-Inn.h9717349.Hotel-Information) 1 mi from Main Street Hyannis 7.8/10 Good (457 reviews) "Was a very nice stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis £84 includes taxes & fees 3 Apr - 4 Apr [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Host-Inn.h9717349.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1560000/1556000/1555968/5ba979da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1560000/1556000/1555968/94e1d316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed | Bathroom | Towels](https://images.trvl-media.com/lodging/2000000/1560000/1556000/1555968/4269b11c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1560000/1556000/1555968/719ceca4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Breeze Inn [](https://www.expedia.co.uk/Hyannis-Hotels-Sea-Breeze-Inn.h1555968.Hotel-Information) 1.1 mi from Main Street Hyannis 7.8/10 Good (194 reviews) "Nice place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin £57 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Hyannis-Hotels-Sea-Breeze-Inn.h1555968.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f7fc1d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/ef69e045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Crown Victorian Suite | Premium bedding, down duvets, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f84dd400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Plaza Suite | Premium bedding, down duvets, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/34fe26da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyannis Plaza Hotel [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information) 0.5 mi from Main Street Hyannis 7.0/10 Good (1,001 reviews) "Love this place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) M £72 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/ef8e0c34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/929a854e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels, soap](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/a8d87212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/895300/895210/103e9cdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Days-Inn-By-Wyndham-West-YarmouthHyannis-Cape-Cod-Area.h895210.Hotel-Information) 1 mi from Main Street Hyannis 7.0/10 Good (1,000 reviews) "Great hotel, friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy £63 includes taxes & fees 6 Apr - 7 Apr [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Days-Inn-By-Wyndham-West-YarmouthHyannis-Cape-Cod-Area.h895210.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/200000/195100/195057/9ef6b148.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/200000/195100/195057/3356a58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/200000/195100/195057/85163ba2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/200000/195100/195057/bdfba585.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Relax Inn Cape Cod [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Relax-Inn-Cape-Cod.h195057.Hotel-Information) 0.9 mi from Main Street Hyannis 6.4/10 (754 reviews) "Good staff, good room, good price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew £65 includes taxes & fees 3 Apr - 4 Apr [](https://www.expedia.co.uk/West-Yarmouth-Hotels-Relax-Inn-Cape-Cod.h195057.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-03&endDate=2026-04-04®ionId=6287458&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Main Street Hyannis | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | --------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Restaurant](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/5a8499c3.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hyannis Travel Inn | 2.5 star property | 9.6Exceptional1,000 reviews | View | | | | | | | ![Interior entrance](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/87d9418f.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Anchor In Distinctive Waterfront Lodging | 3.0 star property | 9.4Exceptional1,000 reviews | View | | | | | | | ![Dining](https://images.trvl-media.com/lodging/27000000/26470000/26468700/26468676/c6220c50.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Sea Street Inn | 4.0 star property | 9.8Exceptional45 reviews | View | | | | | | | ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/490000/480800/480770/056f2544.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Uncommoner Hotel by Reverie Boutique Collection | 3.0 star property | 9.2Wonderful119 reviews | View | | | | | | | ![Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2560000/2558700/2558618/dc2c7156.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn & Suites Cape Cod-West Yarmouth | 2.5 star property | 8.8Excellent1,000 reviews | View | | | | | | ## Top Main Street Hyannis Hotel Reviews ![Margaritaville Resort Cape Cod](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/30f6a06a_y.jpg) ### Margaritaville Resort Cape Cod 8/10 Good "Aceptable " [](https://expedia.co.uk/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) ![Bayside Resort Hotel](https://images.trvl-media.com/lodging/1000000/900000/896700/896697/783b5af0_y.jpg) ### Bayside Resort Hotel 10/10 Excellent "The hotel was clean but needs a little updating . Staff was wonderful . " [](https://expedia.co.uk/West-Yarmouth-Hotels-Bayside-Resort-Hotel.h896697.Hotel-Information) ![Hyannis Harbor Hotel](https://images.trvl-media.com/lodging/1000000/60000/55000/54945/0271fbcb_y.jpg) ### Hyannis Harbor Hotel 10/10 Excellent "Very nice stay, however the bed was very hard, and the pillows were too soft." [](https://expedia.co.uk/Hyannis-Hotels-Hyannis-Harbor-Hotel.h54945.Hotel-Information) ![Courtyard Resort](https://images.trvl-media.com/lodging/116000000/115250000/115243800/115243739/5d7ebe6e_y.jpg) ### Courtyard Resort 10/10 Excellent "A lot of value offered for the price…" [](https://expedia.co.uk/Hyannis-Hotels-Courtyard-Resort.h115243739.Hotel-Information) ![Hyannis Plaza Hotel](https://images.trvl-media.com/lodging/2000000/1120000/1119300/1119277/f7fc1d07_y.jpg) ### Hyannis Plaza Hotel 10/10 Excellent "Love this place " [](https://expedia.co.uk/Hyannis-Hotels-Hyannis-Plaza-Hotel.h1119277.Hotel-Information) ![Comfort Inn Hyannis - Cape Cod](https://images.trvl-media.com/lodging/2000000/1250000/1240500/1240460/b37d6e5b_y.jpg) ### Comfort Inn Hyannis - Cape Cod 8/10 Good "Good price" [](https://expedia.co.uk/Hyannis-Hotels-Comfort-Inn.h1240460.Hotel-Information) ![Anchor In Distinctive Waterfront Lodging](https://images.trvl-media.com/lodging/8000000/7650000/7640900/7640889/87d9418f_y.jpg) ### Anchor In Distinctive Waterfront Lodging 8/10 Good "Marry was great Room outdated and small" [](https://expedia.co.uk/Hyannis-Hotels-Anchor-In-Distinctive-Waterfront-Lodging.h7640889.Hotel-Information) ![Doubletree by Hilton Cape Cod - Hyannis](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314_y.jpg) ### Doubletree by Hilton Cape Cod - Hyannis 8/10 Good "Clean" [](https://expedia.co.uk/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) ![Hyannis Travel Inn](https://images.trvl-media.com/lodging/2000000/1380000/1379200/1379109/5a8499c3_y.jpg) ### Hyannis Travel Inn 10/10 Excellent "Very kind staff. Functional, clean room. Had an early bus and they let me take a few things for breakfast the night before." [](https://expedia.co.uk/Hyannis-Hotels-Hyannis-Travel-Inn.h1379109.Hotel-Information) ## Hotels near other Main Street Hyannis attractions ![John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts](https://images.trvl-media.com/place/6070185/b92268d1-27eb-4055-a07b-800040c40061.jpg) ### John F. Kennedy Hyannis Museum 4.4/5 (259 reviews) Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6070185) ![Cape Cod Maritime Museum which includes a bay or harbor and signage](https://images.trvl-media.com/place/553248635146342095/6c8cea24-96a8-41da-86a8-64397b473956.jpg) ### Cape Cod Maritime Museum You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the beautiful beaches in this family-friendly area or visit its seafood restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635146342095) ![St. Francis Xavier Church featuring signage and a church or cathedral](https://images.trvl-media.com/place/6286986/d75d0252-a6d7-4bb9-9dd9-82f6c06a49ac.jpg) ### St. Francis Xavier Church 4.4/5 (45 reviews) After visiting St. Francis Xavier Church, make a plan to see the other sights and activities in Hyannis. Wander through the beautiful beaches and waterfront in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6286986) ![John F. Kennedy Memorial which includes flowers](https://images.trvl-media.com/place/6286978/9b85082f-75c6-4ae3-ac16-7a3f1c71a2a9.jpg) ### John F. Kennedy Memorial 4.5/5 (110 reviews) Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6286978) ### Hyannis Armory Learn about the local history of Hyannis with a stop at Hyannis Armory. Wander the waterfront and beautiful beaches in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950930054190297088) ### Hyannis Youth & Community Center You can take time to visit Hyannis Youth & Community Center during your travels to Hyannis. Stroll along the beautiful beaches or visit the shops in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248635976357139) ### Zion Union Heritage Museum You can spend an afternoon exploring the galleries in Zion Union Heritage Museum during your trip to Hyannis. Make time to visit the area's shops or simply enjoy its seafood restaurants. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=724958852913086464) ### Commotion Charters Enjoy an outing to Commotion Charters during your stay in Hyannis. Attend a sporting event or simply enjoy the seafood restaurants while you're in the area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532666521) ## Frequently asked questions ### What's the area like around Main Street Hyannis? ### Where is the best place to stay near Main Street Hyannis? ### How many hotels can I expect to find near Main Street Hyannis? ### If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund? ### What can I see and do near Main Street Hyannis?