Title: Hotels Near Cairo Airport - Cairo Regional Airport (CIR) | Expedia.co.uk [Holiday Rentals in Cairo](https://expedia.co.uk/Cairo-Holiday-Rentals.d6626.Travel-Guide-HolidayRentals)[Cairo Regional Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Cairo-Regional.d553248634660000535.Car-Hire-Guide)[Cairo Holidays](https://expedia.co.uk/Cairo.d6626.Holidays-City-Breaks) ![Cairo Ohio River Bridge traversing over the Ohio River at sunset](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6626/5a2a2e7f-cbef-414c-a9c1-20af7a0fca3a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [25 Feb - 26 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248634660000535&startDate=2026-02-25&endDate=2026-02-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [26 Feb - 27 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248634660000535&startDate=2026-02-26&endDate=2026-02-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248634660000535&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248634660000535&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for ${destinationAirportFriendlyName} hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/f1c41457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/74187a0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Iron/ironing board, free cots/infant beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/e2b2c624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cairo I-57 [](https://www.expedia.co.uk/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) 2.1 mi from Cairo, IL (CIR-Cairo Regional) 6.6/10 (282 reviews) "The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6\. I was not satisfied at all." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ReShena £56 includes taxes & fees 6 Mar - 7 Mar [](https://www.expedia.co.uk/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![Laptop workspace, blackout curtains, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) 11.2 mi from Cairo, IL (CIR-Cairo Regional) 6.8/10 (624 reviews) "Affordable for a quick one night stay. Restaurant and gas station next to hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annette £51 includes taxes & fees 3 Mar - 4 Mar [](https://www.expedia.co.uk/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Room, 1 King Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/183a17d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/8720ff7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/ec6ce079.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, alarm clocks](https://images.trvl-media.com/lodging/5000000/4490000/4480300/4480270/228b486a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eagle Inn Charleston [](https://www.expedia.co.uk/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) 10.7 mi from Cairo, IL (CIR-Cairo Regional) 6.6/10 (105 reviews) "Convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcelle £52 includes taxes & fees 26 Feb - 27 Feb [](https://www.expedia.co.uk/Sikeston-Hotels-Eagle-Inn-Charleston.h4480270.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-11&endDate=2026-03-12®ionId=553248634660000535&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Cairo Regional Hotel Reviews ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "Very nice folks who manage the hotel!!" [](https://expedia.co.uk/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Everything!! The room was big. The meal was good. The workers were NICE!!" [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "Very friendly and had an amazing stay so peaceful " [](https://expedia.co.uk/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Wonderful stay at hotel and casino! The band, Next of Kin, was fantastic on Valentine’s Day night. Food was excellent too! Highly recommend!!! " [](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Quality Inn Cairo I-57](https://images.trvl-media.com/lodging/1000000/30000/21600/21513/9d3e181d_y.jpg) ### Quality Inn Cairo I-57 10/10 Excellent "Amenities, microwave, refrigerator,iron and iron board,Shower soap options " [](https://expedia.co.uk/Cairo-Hotels-Quality-Inn-Cairo-I-57.h21513.Hotel-Information) ![Peaceful secluded cabin located near Horseshoe Lake ](https://images.trvl-media.com/lodging/110000000/109740000/109730100/109730068/b6736ddb_y.jpg) ### Peaceful secluded cabin located near Horseshoe Lake 10/10 Excellent "The place was quiet, clean and secluded. Exactly what my wife and I were looking for. Thanks for having us!" [](https://expedia.co.uk/Peaceful-Secluded-Cabin-Located-Near-Horseshoe-Lake.h109730068.Hotel-Information) ![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg) ### Days Inn and Suites by Wyndham Sikeston 10/10 Excellent "Clean comfy stay ! Thanks" [](https://expedia.co.uk/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) ![Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.](https://images.trvl-media.com/lodging/110000000/109110000/109109100/109109006/bd476bf3_y.jpg) ### Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout. 10/10 Excellent "Great place to stay for our hunting trip. Host was helpful and very accommodating." [](https://expedia.co.uk/Tamms-Hotels-Attention-Hunters-Deer-Camp.h109109006.Hotel-Information) ![The Rested Duck Mallard Room](https://images.trvl-media.com/lodging/91000000/90340000/90331100/90331048/29d5afe7_y.jpg) ### The Rested Duck Mallard Room 10/10 Excellent "It’s very nice and comfortable " [](https://expedia.co.uk/The-Rested-Duck-Mallard-Room.h90331048.Hotel-Information) ## Frequently asked questions ### What's the area like near Cairo, IL (CIR-Cairo Regional)? ### What's the best place to stay near Cairo, IL (CIR-Cairo Regional)?