Find hotels in Cairo, IL from £47

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Cairo hotels

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (285 reviews)
"Amenities, microwave, refrigerator,iron and iron board,Shower soap options "
United States
Maurice
The price is £62
includes taxes & fees
8 Jun - 9 Jun
Quality Inn Cairo I-57

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (412 reviews)
"All very just okay "
United States
Sherry
The price is £62
includes taxes & fees
28 May - 29 May
The Riverstone Hotel Charleston-Sikeston

La Center Motel

La Center Motel
2.0 star property
La Center
7.4 out of 10, Good, (20 reviews)
"Property is located just outside of town, so very convenient yet slightly off the beaten path."
United States
Carrie
The price is £47
includes taxes & fees
28 May - 29 May
La Center Motel

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (635 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is £51
includes taxes & fees
8 Jun - 9 Jun
Super 8 by Wyndham Charleston/Sikeston East MO

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is £216
includes taxes & fees
29 May - 30 May
Quiet Country Stay: Modern Home Near Paducah

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
"Great"
United States
Jackson
The price is £59
includes taxes & fees
1 Jun - 2 Jun
Eagle Inn Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Cairo attractions

Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artefacts from this once-thriving river port town.

Cairo Ohio River Bridge traversing over the Ohio River at sunset

Top Cairo Hotel Reviews

More cheap stays in Cairo

Find out more about Cairo

Top reasons to visit Cairo

  • Riverboat Tours: Experience the stunning waterways of Cairo through unique riverboat tours that offer a fresh perspective of the area's natural beauty.
  • Outdoor Adventures: With lovely campgrounds and nature reserves, Cairo is perfect for outdoor enthusiasts seeking adventure amidst scenic landscapes.
  • Historical Charm: Explore the picturesque streets and historic forts that reflect the rich cultural heritage of this riverside town.
  • Welcoming Accommodation: Choose from charming agritourism properties to family-friendly motels, catering to diverse travellers.
  • Community Spirit: Enjoy the inviting atmosphere of Cairo's local community, perfect for relaxation and exploration.

Find great hotels in and around Cairo

Discover a range of accommodation options in Cairo, Illinois, catering to diverse travellers. From charming agritourism properties to convenient motels, you'll find pet-friendly and family-oriented facilities that ensure a welcoming atmosphere for all, including the LGBTQIA community. Whether you seek a cosy inn or a straightforward motel, Cairo offers various choices for a pleasant stay in this unique riverside town.

  • Super 8 by Wyndham Charleston/Sikeston East MO: Located 16.1km from Cairo, Super 8 by Wyndham Charleston/Sikeston East MO is an affordable motel that caters to families and pet owners alike. This welcoming establishment offers essential amenities for children, such as complimentary cribs available upon reservation, ensuring a comfortable stay for families. The property also embraces furry companions with a flexible pet policy, allowing pets onsite for a fee, which makes it a suitable choice for those travelling with pets. With its budget-friendly rates and family-oriented approach, Super 8 is an excellent option for those seeking a no-frills yet accommodating lodging experience.
  • The Riverstone Hotel: Situated 19.3km from Cairo, The Riverstone Hotel is a practical choice for both business travellers and pet owners. This budget-friendly hotel offers a range of amenities that appeal to those on business trips, while also providing a pet-friendly environment. Dogs are welcomed with specific weight restrictions and fees, ensuring that all guests, including four-legged ones, have a comfortable stay. With its blend of functionality and warmth, The Riverstone Hotel is perfect for those needing convenience during their travels while still desiring a hospitable atmosphere.
  • Quality Inn Cairo I-57: Located right in Cairo, Quality Inn Cairo I-57 combines affordability with family-friendly and pet-friendly accommodations. This hotel provides essential services for children, including a free crib service, and allows pets with certain conditions, such as fees and deposits. The staff is dedicated to ensuring a pleasant stay for all guests, including those with service animals, which are welcomed without additional fees. With its prime location and comprehensive amenities, Quality Inn Cairo I-57 is an ideal choice for families and pet owners looking for a convenient and comfortable stay.

Where to stay near Cairo

Cairo, Illinois, offers a delightful blend of outdoor adventures and historical charm. Visitors can explore the picturesque streets of Cairo and enjoy family-friendly activities in the surrounding areas. With inviting campgrounds and a welcoming local community, travellers will find a unique atmosphere perfect for relaxation and exploration. Nearby cities also provide opportunities for business and leisure, making Cairo an excellent base for a memorable holiday experience.

  • Wickliffe: Situated a mere 9.7km from Cairo, Wickliffe is a charming city that offers visitors a delightful blend of outdoor adventure and scenic beauty. This area is particularly popular among couples seeking a romantic getaway, as well as outdoor enthusiasts. The local attractions include a stunning lake, a national state park, and lush forests, making it an ideal spot for nature walks and picnics. Golf lovers will appreciate the nearby golf courses, while the recreational areas provide ample opportunities for relaxation and leisure. Wickliffe’s visitor numbers peak in March to April and August, ensuring a vibrant atmosphere during these months.
  • Mound City: Also located 9.7km from Cairo, Mound City is a haven for adventurers and nature lovers alike. This city attracts visitors seeking outdoor experiences and romantic outings, with its charming recreational areas and parks. The proximity to forests and lakes offers numerous opportunities for exploration and leisure activities such as hiking and fishing. Mound City sees a surge in visitors during March, July, and October, making it a lively destination during these periods. Whether you’re enjoying a day at the recreation park or hitting the golf course, Mound City promises a memorable travel experience.
  • Wyatt: Just 11.3km from Cairo, Wyatt is a welcoming city that caters to families and those looking for a city-themed experience. This area is particularly appealing to families, providing a variety of activities including golf, visits to dog parks, and the chance to explore local urban parks. Wyatt’s event conference venues also add a unique touch for those attending special gatherings. The peak visitor months are June to August, ensuring a bustling atmosphere during the summer holidays. With its blend of recreational activities and urban charm, Wyatt is a delightful stop on your vacation.

Things to do in Cairo

Cairo, Illinois, offers an array of outdoor and adventurous activities perfect for a scenic getaway. Visitors can explore lovely campgrounds and recreational areas, making it ideal for nature enthusiasts. A highlight of your trip should be the riverboat tours, which provide a unique perspective of the area's beautiful waterways. Enjoy the tranquillity and charm that Cairo has to offer as you immerse yourself in its natural splendour.

Shopping

Cairo offers a quaint shopping experience with local shops for unique gifts. If you're up for a drive, visit the nearby Cape Girardeau Mall for a wider selection, including popular retailers and department stores. The local markets also provide charming handmade items to take home.

Recreation

The Riverfront Park in Cairo offers scenic walking trails alongside the Ohio River, perfect for leisurely strolls and picnics. For relaxation, visit the nearby wellness centre, where you can enjoy rejuvenating spa treatments and calming yoga sessions amidst tranquil surroundings.

Adventure

The Cairo Riverfront is a scenic spot offering stunning views of the confluence of the Mississippi and Ohio Rivers, perfect for leisurely strolls or picnics. For a thrilling experience, visit the nearby Cache River State Natural Area, where you can explore wetlands, hike trails, and spot diverse wildlife.

Nightlife

Experience the vibrant nightlife in Cairo at the Riverfront Grill, where you can enjoy tasty bites and live music by the riverside. For a more laid-back atmosphere, head to the Cairo Brewing Company for unique craft beers and a friendly local vibe.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Cairo

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Cairo are November to January, where the prices are slightly lower. This is in comparison to April to May and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Cairo is Tuesday. The most expensive day to stay in Cairo is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to refine your preferences, such as your budget, desired location, and type of accommodation. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels currently available. To find the best prices and offers, arrange the price filter from low to high.
  • Consider bundling your trip: You can save money by combining your hotel stay in Cairo with your flights and activities through an Expedia package deal.

Find the best attractions in and around Cairo

Cairo, Illinois, is an excellent destination for outdoor enthusiasts seeking adventure and stunning scenery. Notable attractions include nature reserves, state parks, and historic forts, providing a rich blend of culture and exploration. Whether you’re after breathtaking views or engaging experiences, Cairo offers a variety of activities to suit every traveller's interests.

  • Columbus-Belmont State Park: Located 27.4km from Cairo, this national park offers stunning scenery and a wealth of outdoor adventures. Enjoy hiking trails and picnicking areas that let you soak in the natural beauty of the region.
  • Ballard Wildlife Management Area: Just 8.0km from Cairo, this reserve provides a historical perspective with budget-friendly access to nature. It's an ideal spot for birdwatching and exploring the local flora and fauna.
  • Fort Defiance State Park: Situated within Cairo, this historic fort is a cultural gem. Discover the rich history of the area and enjoy picturesque views where the Mississippi and Ohio Rivers converge.

Best time to go to Cairo

The best time to visit Cairo is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January35.2°F (1.8°C)Light RainMostly SunnyModerately LowSlightly Low
February38.5°F (3.6°C)Light RainMostly SunnyModerately LowAverage
March48.7°F (9.3°C)Light RainMostly SunnyModerately HighAverage
April57.7°F (14.3°C)Light RainMostly SunnyModerately HighSlightly High
May67.5°F (19.7°C)Light RainMostly SunnyAverageSlightly High
June76.5°F (24.7°C)Light RainMostly SunnyAverageAverage
July79.0°F (26.1°C)Light RainMostly SunnyAverageAverage
August77.2°F (25.1°C)Light RainMostly SunnyModerately HighSlightly High
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October60.1°F (15.6°C)Light RainMostly SunnyAverageAverage
November47.8°F (8.8°C)Light RainMostly SunnyModerately LowSlightly Low
December40.6°F (4.8°C)Light RainMostly SunnyAverageSlightly Low

The nearest major airports for your trip to Cairo

When visiting Cairo, Illinois, you have several airport options. Cape Girardeau, MO (CGI-Cape Girardeau Municipal) is 41.8km away, with good hotel choices such as Drury Plaza Hotel Cape Girardeau Conference Center and Courtyard by Marriott Cape Girardeau Downtown, both around 9.7km from the airport. Another option is Marion, IL (MWA-Williamson County Regional), located 83.7km away; nearby hotels include Drury Inn & Suites Marion, just 3.2km from the airport. Lastly, Paducah, KY (PAH-Barkley Regional) is 37.0km from Cairo, with accommodations like Harrah's Metropolis Hotel & Casino, 9.7km from the airport. Transportation services are readily available to connect you with these hotels.

Frequently asked questions

What is the best area to stay in Cairo?
The best area to stay in Cairo, Illinois, is near the downtown historic district, particularly around Commercial Avenue.

This area, though small, represents the heart of Cairo's history and offers the most convenient access to its remaining landmarks. Commercial Avenue was once the main commercial thoroughfare, and while many buildings are now vacant, it provides a glimpse into the town's past. Travellers will find the most accessible options for overnight stays here.

For history enthusiasts, staying in this central area is ideal. You're within walking distance of historic buildings and the confluence of the Ohio and Mississippi Rivers, a significant geographical point.
What are the best hotels in Cairo that travellers recommend?
For a recommended hotel in Cairo, Illinois, consider the Quality Inn Cairo I-57.

The Quality Inn Cairo I-57 offers a comfortable stay with amenities such as air conditioning, free breakfast including a full breakfast, and a kitchen in the rooms. Guests appreciate the nice, clean rooms and the quite good breakfast. The staff also receives positive comments for being nice. For convenience, the hotel provides free self-parking, accessible van parking, and parking for RVs, buses, and trucks.
What are the best family hotels in Cairo?
For a family-friendly hotel in Cairo, the Quality Inn Cairo I-57 is a highly suitable option.

This hotel offers a range of complimentary amenities that are ideal for families. Guests can enjoy free WiFi, free toiletries, and free self-parking. Furthermore, the hotel provides a complimentary full breakfast, and cribs are available for free, which is very convenient for those travelling with young children. Guests have consistently praised the nice, clean rooms, the quite good breakfast, and the nice staff, all contributing to a pleasant stay.
What hotels in Cairo offer free breakfast?
For hotels in Cairo that offer complimentary breakfast, the Quality Inn Cairo I-57 is a superb option.

The Quality Inn Cairo I-57 provides guests with a free full breakfast, ensuring a great start to the day. This hotel also offers free WiFi and complimentary self-parking, adding to the convenience. Guests have frequently commented on the nice, clean rooms and the quite good breakfast. The staff are also regularly mentioned for being nice. This hotel is located within easy reach of the Mississippi River and the Ohio River.
What are the top pet-friendly hotels in Cairo?
For pet-friendly accommodation in Cairo, the Quality Inn Cairo I-57 is a highly recommended option.

The Quality Inn Cairo I-57 permits pets, with a cleaning amount applicable for their stay. It also offers a complimentary full breakfast, which many guests describe as quite good. Reviewers often mention the nice and clean rooms, and the staff are frequently praised for being friendly. This hotel is also conveniently located near the Mississippi River and the Ohio River.
What are the best budget hotels in Cairo?
For a much-loved budget hotel in Cairo, the Quality Inn Cairo I-57 is an excellent option.

This hotel offers convenient amenities such as complimentary WiFi, free toiletries, and free self-parking. Guests particularly appreciate the complimentary full breakfast provided. Reviews frequently mention the nice, clean rooms, the quite good breakfast, and the nice staff.
What are the best hotels in Cairo near Mississippi River?
For a hotel near the Mississippi River in Cairo, consider the Quality Inn Cairo I-57.

This hotel offers convenient amenities for families, including free cots and complimentary full breakfast. Guests frequently praise the nice, clean rooms and the quite good breakfast. The staff also receive positive comments for their helpfulness. You will also benefit from free WiFi, complimentary toiletries, and free self-parking.
When is the best time to go to Cairo?
The best time to visit Cairo, Illinois is during the late spring (April to May) and early autumn (September to October) months.

These periods offer the most pleasant weather for exploring the area. During late spring, temperatures are mild, typically ranging from 15°C to 25°C, and the natural scenery along the rivers is lush. Early autumn brings similar comfortable temperatures, often between 18°C and 28°C, with the added beauty of changing leaves.

For couples looking for a relaxed getaway, these shoulder seasons are ideal. The weather is great for walking along the riverfront, visiting historic sites like the Custom House Museum, or enjoying the quiet charm of the town without the extreme heat of summer. It's a great time for photography as well, capturing the blend of history and nature.

Solo travellers will also appreciate the comfortable conditions for exploring the area's historical significance, particularly its role in the Civil War.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Cairo.
How can I save on a Cairo hotel booking with Expedia?
Members always get our best prices. Find our best Cairo hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Cairo hotel?
Prices for hotels in Cairo often vary, but you can find a great deal from £47 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia