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Our top choices for Cairo hotels

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (284 reviews)
"Amenities, microwave, refrigerator,iron and iron board,Shower soap options "
United States
Maurice
The price is £62
includes taxes & fees
23 Apr - 24 Apr
Quality Inn Cairo I-57

La Center Motel

La Center Motel
2.0 star property
La Center
7.6 out of 10, Good, (19 reviews)
"Quiet and convenient."
United States
Alma
The price is £47
includes taxes & fees
13 Apr - 14 Apr
La Center Motel

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (411 reviews)
"Clean "
United States
Chris
The price is £68
includes taxes & fees
16 Apr - 17 Apr
The Riverstone Hotel Charleston-Sikeston

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (629 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is £54
includes taxes & fees
19 Apr - 20 Apr
Super 8 by Wyndham Charleston/Sikeston East MO

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is £215
includes taxes & fees
15 Apr - 16 Apr
Quiet Country Stay: Modern Home Near Paducah

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105 reviews)
"The hotel needs a renovation. For the price I didn’t expect much, but it feels neglected."
United States
Britani
The price is £45
includes taxes & fees
2 May - 3 May
Eagle Inn Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Cairo attractions

Learn more about Cairo

At the confluence of the Mississippi and Ohio rivers, explore Cairo's historic Fort Defiance Park with its sweeping water views. History buffs shouldn't miss the Custom House Museum, where you can discover artefacts from this once-thriving river port town.

Cairo Ohio River Bridge traversing over the Ohio River at sunset

Top Cairo Hotel Reviews

More cheap stays in Cairo

Find out more about Cairo

Top reasons to visit Cairo

  • Outdoor Adventures: Cairo offers a plethora of recreational activities, from exploring scenic landscapes to golfing at local courses.
  • Cultural Heritage: Discover the rich history of Cairo through its historic forts and vibrant neighbourhoods, perfect for curious travellers.
  • National Parks: Experience the natural beauty of nearby national parks, ideal for hiking and nature walks.
  • Family-Friendly Atmosphere: Cairo's charming environment makes it perfect for family getaways with plenty of engaging activities.
  • Diverse Accommodations: Choose from a variety of lodging options, including agritourism properties and pet-friendly motels.

Find great hotels in and around Cairo

Cairo, Illinois offers a diverse selection of accommodations, including agritourism properties and motels, perfect for a range of travellers. Whether you're seeking pet-friendly options for family getaways or business-themed stays, you'll discover a variety of hotels that cater to your needs. From the best Cairo hotels to convenient motels near the area, your ideal lodging experience awaits in this charming town.

  • Super 8 by Wyndham Charleston/Sikeston East MO: Situated a mere 6.2km from Cairo, Super 8 by Wyndham Charleston/Sikeston East MO offers a welcoming atmosphere ideal for family and pet-friendly vacations. This motel provides thoughtful amenities for children, ensuring a comfortable stay for families. With complimentary cribs available upon reservation and a pet-friendly policy that allows certain pets onsite, it’s a great choice for those travelling with furry companions. Guests appreciate the convenient access to local attractions and the friendly service that makes for a pleasant stay.
  • Quality Inn Charleston - Sikeston: Located 7.5km from Cairo, Quality Inn Charleston - Sikeston caters to both business and leisure travellers with its pet-friendly environment. Designed with the business traveller in mind, the hotel features a dedicated business centre to facilitate work needs. Pets are permitted with some restrictions, ensuring that your four-legged friends are welcome too. The hotel’s combination of comfort and functionality is praised by guests, making it a reliable choice for those who need to balance work and leisure during their stay.
  • Quality Inn Cairo I-57: Nestled within Cairo, Quality Inn Cairo I-57 is an excellent option for families and pet owners looking for a comfortable retreat. This hotel provides ample amenities for children, including complimentary cribs and a first aid kit for peace of mind. With a pet policy that allows dogs and ensures their comfort, it is perfect for those wishing to travel with their pets. Guests often commend the hotel for its family-friendly atmosphere and accommodating staff, making it a varied choice for visitors.

Where to stay near Cairo

Cairo, Illinois, offers a delightful blend of outdoor adventures and historical charm, making it perfect for families and curious travellers alike. Explore the scenic landscapes and vibrant neighbourhoods in and around the city, where you’ll find family-friendly atmospheres and fascinating local history. With a range of accommodations and activities, Cairo presents an ideal getaway for those seeking both relaxation and exploration in a quaint American setting.

  • Wickliffe: Situated a mere 3.7km from Cairo, Wickliffe is a charming city that attracts visitors year-round, with peaks in March to April and August. Known for its stunning outdoor scenery, Wickliffe offers a romantic escape with numerous recreational areas and an arts centre. Nature enthusiasts will appreciate the nearby national state park and lake, perfect for a leisurely day of exploration or a picnic. The area's serene ambiance makes it an ideal spot for couples and nature lovers alike.
  • Mound City: Also located 3.7km from Cairo, Mound City is a delightful destination that welcomes travellers throughout the year, with peak visits in March, July, and October. This city is renowned for its adventurous spirit, offering a variety of outdoor activities including golf and educational opportunities. Mound City is surrounded by picturesque landscapes, including a lovely lake and a national park, making it perfect for those seeking both adventure and natural beauty. Whether you’re hitting the golf course or hiking through the forest, Mound City promises a memorable experience.
  • Wyatt: Just 4.3km away from Cairo, the city of Wyatt is a hidden gem that captures the hearts of visitors, especially during the peak months of April and June to July. Known for its romantic outdoor settings, Wyatt offers a peaceful recreational area where you can unwind and enjoy the natural beauty. Close to a lovely lake and national park, it’s a perfect spot for couples seeking tranquility amidst nature. With its inviting atmosphere, Wyatt is sure to enhance your vacation experience.

Things to do near Cairo

Cairo offers a delightful escape for those seeking outdoor adventure and picturesque scenery. Visitors can enjoy various activities, including exploring the recreational areas and playing a round of golf at the local courses. The town’s charm lies in its natural beauty, making it an ideal destination for leisurely pursuits and outdoor fun.

Shopping

Cairo offers quaint shopping experiences with local charm. For unique gifts, visit The Book Bug, located 13.7km away. If you're up for a drive, check out larger shopping malls nearby for a wider selection and more variety.

Recreation

At Boot Heel Golf Club, enjoy a round of golf surrounded by scenic landscapes, perfect for outdoor enthusiasts. Meanwhile, eDen Spa & Salon provides rejuvenating body treatments that offer a tranquil escape, allowing you to relax and unwind after a day of exploration in Cairo.

Adventure

For an adventurous day, explore Limekin Springs Trail Trailhead, a scenic hiking trail located 12.4km from Cairo, offering stunning outdoor views. Alternatively, enjoy a fun-filled time at Cape Splash Family Aquatic Center, a vibrant waterpark situated 19.3km away, perfect for family entertainment and adventure.

Nightlife

Experience the vibrant nightlife at the Cairo Wine Bar on 2nd Street, where you can savour exquisite wines and local cheeses. For a lively atmosphere, visit the Riverfront Tavern, offering live music and a variety of craft beers, perfect for mingling with friendly locals.

Booking tips and Expedia advantages for Cairo

For a budget-friendly visit to Cairo, Illinois, consider travelling between November and January, when accommodation prices are lower, and aim to stay on a Tuesday for the best rates. Utilise Expedia’s search tools to filter for eco-certified hotels and sort by price to find the best deals. You can also save by booking a package that combines flights, hotel, and activities. Additionally, explore free local attractions and take advantage of public transport to keep costs down during your stay.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Cairo are November to January, where the prices are slightly lower. This is in comparison to April to June, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Cairo is Tuesday. The most expensive day to stay in Cairo is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to refine your preferences, such as your budget, desired location, and preferred type of accommodation. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels currently available. To find the best prices and offers, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can potentially save money by combining your hotel reservation in Cairo with your flights and activities by opting for an Expedia package.

Find the best attractions in and around Cairo

Cairo, Illinois, offers a delightful blend of outdoor adventures and cultural experiences, making it perfect for those seeking scenic beauty and historical intrigue. Key attractions include national parks, historic forts, and modern colleges, catering to a variety of interests. Whether you fancy exploring nature or immersing yourself in local heritage, Cairo's diverse offerings promise a memorable visit.

  • Fort Defiance State Park: Immerse yourself in history at Fort Defiance State Park, where you can explore the remnants of a historic fort. Nestled within Cairo, this park offers cultural vibes and showcases the area's rich heritage, making it a unique educational experience.
  • Ballard Wildlife Management Area: Located 3.1km from Cairo, Ballard Wildlife Management Area serves as a peaceful reserve. With its historical significance and budget-friendly access, it’s ideal for birdwatching and enjoying the serenity of nature.
  • Columbus-Belmont State Park: Adventure awaits at Columbus-Belmont State Park, situated 10.6km away. Known for its stunning outdoor scenery, this national park offers various recreational activities, from hiking to fishing, perfect for nature enthusiasts.

Best time to go to Cairo

The best time to visit Cairo is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January35.2°F (1.8°C)Light RainMostly SunnyModerately LowSlightly Low
February38.5°F (3.6°C)Light RainMostly SunnyModerately LowAverage
March48.7°F (9.3°C)Light RainMostly SunnyModerately HighAverage
April57.7°F (14.3°C)Light RainMostly SunnyModerately HighSlightly High
May67.5°F (19.7°C)Light RainMostly SunnyAverageAverage
June76.5°F (24.7°C)Light RainMostly SunnyAverageSlightly High
July79.0°F (26.1°C)Light RainMostly SunnyAverageSlightly High
August77.2°F (25.1°C)Light RainMostly SunnyModerately HighAverage
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October60.1°F (15.6°C)Light RainMostly SunnyAverageAverage
November47.8°F (8.8°C)Light RainMostly SunnyModerately LowSlightly Low
December40.6°F (4.8°C)Light RainMostly SunnyAverageSlightly Low

The nearest major airports for your trip to Cairo

If you're planning to visit Cairo, Illinois, you have several airport options to consider. Barkley Regional Airport in Paducah, KY (PAH) is situated 14.3km away, with nearby accommodation such as The Respite Bed and Breakfast and The 1857, both within a 10-mile radius. Alternatively, Williamson County Regional Airport in Marion, IL (MWA) is 32.3km from Cairo, offering hotels like Drury Inn & Suites Marion just 1.2km away. Lastly, Cape Girardeau Municipal Airport in Missouri (CGI) is 16.2km distant, with options like Drury Plaza Hotel Cape Girardeau Conference Center conveniently located 3.7km from the airport.

Frequently asked questions

What is the best area to stay in Cairo?
The best area to stay in Cairo, Illinois, is near the downtown historic district, particularly around Commercial Avenue.

This area, though small, represents the heart of Cairo's history and offers the most convenient access to its remaining landmarks. Commercial Avenue was once the main commercial thoroughfare, and while many buildings are now vacant, it provides a glimpse into the town's past. Travellers will find the most accessible options for overnight stays here.

For history enthusiasts, staying in this central area is ideal. You're within walking distance of historic buildings and the confluence of the Ohio and Mississippi Rivers, a significant geographical point.
What are the best hotels in Cairo that travellers recommend?
For a recommended hotel in Cairo, Illinois, consider the Quality Inn Cairo I-57.

The Quality Inn Cairo I-57 offers a comfortable stay with amenities such as air conditioning, free breakfast including a full breakfast, and a kitchen in the rooms. Guests appreciate the nice, clean rooms and the quite good breakfast. The staff also receives positive comments for being nice. For convenience, the hotel provides free self-parking, accessible van parking, and parking for RVs, buses, and trucks.
What are the best family hotels in Cairo?
For a family-friendly hotel in Cairo, the Quality Inn Cairo I-57 is a highly suitable option.

This hotel offers a range of complimentary amenities that are ideal for families. Guests can enjoy free WiFi, free toiletries, and free self-parking. Furthermore, the hotel provides a complimentary full breakfast, and cribs are available for free, which is very convenient for those travelling with young children. Guests have consistently praised the nice, clean rooms, the quite good breakfast, and the nice staff, all contributing to a pleasant stay.
What hotels in Cairo offer free breakfast?
For hotels in Cairo that offer complimentary breakfast, the Quality Inn Cairo I-57 is a superb option.

The Quality Inn Cairo I-57 provides guests with a free full breakfast, ensuring a great start to the day. This hotel also offers free WiFi and complimentary self-parking, adding to the convenience. Guests have frequently commented on the nice, clean rooms and the quite good breakfast. The staff are also regularly mentioned for being nice. This hotel is located within easy reach of the Mississippi River and the Ohio River.
What are the top pet-friendly hotels in Cairo?
For pet-friendly accommodation in Cairo, the Quality Inn Cairo I-57 is a highly recommended option.

The Quality Inn Cairo I-57 permits pets, with a cleaning amount applicable for their stay. It also offers a complimentary full breakfast, which many guests describe as quite good. Reviewers often mention the nice and clean rooms, and the staff are frequently praised for being friendly. This hotel is also conveniently located near the Mississippi River and the Ohio River.
What are the best budget hotels in Cairo?
For a much-loved budget hotel in Cairo, the Quality Inn Cairo I-57 is an excellent option.

This hotel offers convenient amenities such as complimentary WiFi, free toiletries, and free self-parking. Guests particularly appreciate the complimentary full breakfast provided. Reviews frequently mention the nice, clean rooms, the quite good breakfast, and the nice staff.
What are the best hotels in Cairo near Mississippi River?
For a hotel near the Mississippi River in Cairo, consider the Quality Inn Cairo I-57.

This hotel offers convenient amenities for families, including free cots and complimentary full breakfast. Guests frequently praise the nice, clean rooms and the quite good breakfast. The staff also receive positive comments for their helpfulness. You will also benefit from free WiFi, complimentary toiletries, and free self-parking.
When is the best time to go to Cairo?
The best time to visit Cairo, Illinois is during the late spring (April to May) and early autumn (September to October) months.

These periods offer the most pleasant weather for exploring the area. During late spring, temperatures are mild, typically ranging from 15°C to 25°C, and the natural scenery along the rivers is lush. Early autumn brings similar comfortable temperatures, often between 18°C and 28°C, with the added beauty of changing leaves.

For couples looking for a relaxed getaway, these shoulder seasons are ideal. The weather is great for walking along the riverfront, visiting historic sites like the Custom House Museum, or enjoying the quiet charm of the town without the extreme heat of summer. It's a great time for photography as well, capturing the blend of history and nature.

Solo travellers will also appreciate the comfortable conditions for exploring the area's historical significance, particularly its role in the Civil War.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Cairo.
How can I save on a Cairo hotel booking with Expedia?
Members always get our best prices. Find our best Cairo hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a Cairo hotel?
Prices for hotels in Cairo often vary, but you can find a great deal from £45 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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