Beginning of main content

Business Hotel in Buffalo, New York

Search Flights

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Buffalo Hotels

Search Flight + Hotel

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Top Buffalo Neighborhoods for Business Hotel

Featured Buffalo Business Hotel

See all 116 Hotels in Buffalo
Quality Inn Buffalo Airport

Quality Inn Buffalo Airport

4217 Genesee St, Cheektowaga
2.5 out of 5.0
3.3 out of 5 (203 reviews)
Beds are hardThe bed was very hard other than that excellent. Full hot breakfast included.
  18 Apr 2017

£57

£57
Holiday Inn Express & Suites Buffalo Downtown

Holiday Inn Express & Suites Buffalo Downtown

601 Main St, Buffalo
2.5 out of 5.0
4.1 out of 5 (194 reviews)
Convenient Good city access Clean Active night life area in the city
  5 May 2017

£70

£70
Wyndham Garden Buffalo Williamsville

Wyndham Garden Buffalo Williamsville

5195 Main Street, Williamsville
3.5 out of 5.0
4.7 out of 5 (242 reviews)
Updated hotel and very cleanConvenient to coffee shops & restaurants - easy walk. Some room noise being on Main Street.
  10 Jun 2017

£103

£103
Salvatore's Garden Place Hotel, an Ascend Hotel Collection

Salvatore's Garden Place Hotel, an Ascend Hotel Collection

6615 Transit Road, Williamsville
3.0 out of 5.0
4.2 out of 5 (277 reviews)
Nice hotelRoom was quote comfortable. Very close to airport too.
  30 Apr 2017

£93

£93
Adam's Mark Buffalo

Adam's Mark Buffalo

120 Church St, Buffalo
3.0 out of 5.0
3.4 out of 5 (824 reviews)
Way better than expectedNot sure why would someone give bellow 4* for this nice hotel. We had a pleasant stay and there is nothing to complain. The day prior to this we stayed at Renaissance/Philadelphia and I got somewhat a similar room at Adam's Mark for half of that price. Definitely I would recommend Family/Friends ...
  23 May 2017

£68

£68
Country Inn and Suites Buffalo South

Country Inn and Suites Buffalo South

164b Slade Ave, West Seneca
2.5 out of 5.0
4.5 out of 5 (387 reviews)
Nice hotel near zoo and botanical gardens Great hotel with a nice breakfast, Salt water pool, and friendly staff. We had a 2 room suite.
  15 May 2017

£84

£84
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

Two Fountain Plaza, Buffalo
3.5 out of 5.0
4.1 out of 5 (519 reviews)
Good deal!Nice place to stay close to Niagara! Ambience was really good.
  30 May 2017

£102

£102
Hampton Inn & Suites Buffalo Airport

Hampton Inn & Suites Buffalo Airport

133 Buell Avenue, Cheektowaga
2.5 out of 5.0
4.3 out of 5 (138 reviews)
A little noisy, but then, it's next to the airport. All the usual amenities were perfectly acceptable.
  1 May 2017

£96

£96
Embassy Suites Buffalo

Embassy Suites Buffalo

200 Delaware Avenue, Buffalo
3.5 out of 5.0
4.5 out of 5 (458 reviews)
The accommodations were excellent and staff was veLocation was excellent and the stay in Buffalo will make a return visit to your Hotel a definate.
  24 May 2017

£107

£107
Hyatt Place Buffalo/Amherst

Hyatt Place Buffalo/Amherst

5020 Main Street, Amherst
3.0 out of 5.0
4.6 out of 5 (76 reviews)
Nice hotel... Needs better breakfast!Stay was nice. The breakfast could be better. I do not eat pork and they only offer pork choices. Eggs were not that good and French toast was hard.
  2 Jun 2017

£96

£96
Map

Recently booked Buffalo hotels

Wyndham Garden Buffalo Williamsville
3.5 out of 5.0
Last booking: 6 minutes ago
Orchard Park Inn
2.0 out of 5.0
Last booking: 22 minutes ago
Comfort Suites Buffalo Airport
2.5 out of 5.0
Last booking: 26 minutes ago
Red Roof Inn Buffalo - Niagara Airport
2.0 out of 5.0
Last booking: 26 minutes ago
Best Western Plus Galleria Inn & Suites
2.5 out of 5.0
Last booking: 26 minutes ago
Buffalo Marriott Harborcenter
3.5 out of 5.0
Last booking: 30 minutes ago
Red Roof Inn PLUS+ University at Buffalo - Amherst
2.5 out of 5.0
Last booking: 40 minutes ago
Embassy Suites Buffalo
3.5 out of 5.0
Last booking: 44 minutes ago
Hyatt Place Buffalo/Amherst
3.0 out of 5.0
Last booking: 50 minutes ago

Pocket Guide: Business Hotel Hotels in Buffalo

Search for hotels in Buffalo on Expedia.co.uk. You can easily find your hotels in Buffalo using one of the methods below:

  • View our selection of featured hotels in Buffalo
  • Use the map to find hotels in the Buffalo neighborhood you prefer
  • Use the filters to see hotels in a specific area of Buffalo, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Buffalo
  • Enter your travel dates to view the best deals on hotels in Buffalo - while they last